Integrin-linked kinase controls Notch1 signaling by down-regulation of protein stability through Fbw7 ubiquitin ligase

Molecular and Cellular Biology

Volumn 27, Issue 15, 2007, Pages 5565-5574

  Jung Soon, Mo ^a   Mi Yeon, Kim ^a   Seung Ok, Han ^a   In Sook, Kim ^a   Eun Jung, Ann ^a   Kyu, Shik Lee ^a   Mi Sun, Seo ^a   Jin Young, Kim ^a   Hee Sae, Lee ^a   Jeen Woo, Park ^b   Eui Ju, Choi ^c   Jae, Young Seong ^d   Cheol, Joe O ^e   Reinhard, Faessler ^f   Hee Sea, Park ^a  

^a Chonnam National University   (South Korea)

^b Kyungpook National University   (South Korea)

^c Korea University   (South Korea)

^d Korea University College of Medicine   (South Korea)

^e Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

^f MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

INTEGRIN LINKED KINASE; NOTCH1 RECEPTOR; PROTEASOME; PROTEIN KINASE; UBIQUITIN; UBIQUITIN LIGASE FBW7; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BASAL CELL CARCINOMA; CELL FUNCTION; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; HUMAN TISSUE; MELANOMA; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; SIGNAL TRANSDUCTION; SQUAMOUS CELL CARCINOMA; UPREGULATION; WILD TYPE;

ANIMALS; CARCINOMA, BASAL CELL; CARCINOMA, SQUAMOUS CELL; CELL NUCLEUS; DOWN-REGULATION; HUMANS; MELANOMA; MICE; NIH 3T3 CELLS; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN-SERINE-THREONINE KINASES; RECEPTOR, NOTCH1; SERINE; SIGNAL TRANSDUCTION; SKIN NEOPLASMS; SKP CULLIN F-BOX PROTEIN LIGASES; THERMODYNAMICS; TRANSCRIPTION, GENETIC; UP-REGULATION;

EID: 34547164997     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.02372-06     Document Type: Article

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