Molecular model of a lattice of signalling proteins involved in bacterial chemotaxis

Nature Cell Biology

Volumn 2, Issue 11, 2000, Pages 792-796

  Shimizu, Thomas S ^a   Le Novère, Nicolas ^a   Levin, Matthew D ^a   Beavil, Andrew J ^b   Sutton, Brian J ^b   Bray, Dennis ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CHEMORECEPTOR; CHEMOTAXIS; ENZYME PHOSPHORYLATION; ESCHERICHIA COLI; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION; STOICHIOMETRY;

BACTERIAL PROTEINS; CHEMOTAXIS; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; MEMBRANE PROTEINS; MODELS, MOLECULAR; PROTEIN STRUCTURE, QUATERNARY; RECEPTORS, CELL SURFACE; SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP; THERMOTOGA MARITIMA;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 0033778277     PISSN: 14657392     EISSN: None     Source Type: Journal    
DOI: 10.1038/35041030     Document Type: Article

References (42)

1. Evaluation of the CASP2 docking section
2. The application of stereolithography to the fabrication of accurate molecular models
3. The use of solid physical models for the study of macromolecular assembly
4. Polar location of the chemoreceptor complex in the Eseherichia coli cell
5. Control of bacterial chemotaxis
6. The two-component signaling pathway of bacterial chemotaxis: A molecular view of signal transduction by receptors, kinases, and adaptation enzymes
7. Bacterial tactic responses
8. Structure of CheA, a signal-transducing histidine kinase
9. Two binding modes reveal flexibility in kinase/response regulator interactions in the bacterial chemotaxis pathway
10. Liberation of an interaction domain from the phosphotransfer region of CheA, a signaling kinase of Escherichia coli
11. The carboxy-terminal portion of the CheA kinase mediates regulation of autophosphorylation by transducer and CheW
12. A fragment liberated from the Escherichia coli CheA kinase that blocks stimulatory, but not inhibitory, chemoreceptor signaling
13. Genetic evidence for interaction between Chew and Tsr proteins during chemoreceptor signaling by Escherichia coli
14. The interpretation of protein structures: Estimation of static accessibility
15. Four-helical-bundle structure of the cytoplasmic domain of a serine chemotaxis receptor
16. MOLMOL: A program for display and analysis of macromolecular structures
17. Signaling domain of the aspartate receptor is a helical hairpin with a localized kinase docking surface: Cysteine and disulfide scanning studies
18. Jr Molecular evolution of the C-terminal cytoplasmic domain of a supeffamily of bacterial receptors involved in taxis
19. Assembly of an MCP receptor, CheW, and kinase CheA complex in the bacterial chemotaxis signal transduction pathway
20. CheZ has no effect on flagellar motors activated by CheY(13DK106YW)
21. Molecular cloning of chemotaxis genes and overproduction of gene products in the bacterial sensing system
22. Sensory transduction in bacterial chemotaxis
23. Covalent modification regulates ligand binding to receptor complexes in the chemosensory system of Escherichia coli
24. Computer analysis of the binding reactions leading to a transmembrane receptor-linked multiprotein complex involved in bacterial chemotaxis
25. Receptor-mediated protein kinase activation and the mechanism of transmembrane signaling in bacterial chemotaxis
26. Attenuation of sensory receptor signaling by covalent modification
27. Adaptational 'crosstalk' and the crucial role of methylation in chemotactic migration by Escherichia coli
28. Photolabeling of CheR methyltransferase with S-adenosyl-L-methionine (AdoMet). Studies on the AdoMet binding site
29. The receptor binding site for the methyltransferase of bacterial chemotaxis is distinct from the sites of methylation
30. Efficient adaptational demethylation of chemoreceptors requires the same enzyme-docking site as efficient methylatinn
31. The response regulators CheB and CheY exhibit competitive binding to the kinase CheA
32. Signal processing times in bacterial chemotaxis
33. Bacterial chemoreceptor signaling probed by flash photoralease of a caged serine
34. Receptor clustering as a cellular mechanism to control sensitivity
35. Heightened sensitivity of a lattice of membrane receptors
36. Parallel pathways for transduction of chemotactic signals in Eseheriehia coli
37. High- and low-abundance chemoreceptors in Escherichia coli: Differential activities associated with closely related cytoplasmic domains
38. Chimeric chemoreceptors in Escherichia coli: Signaling properties of Tar-Tap and Tap-Tar Hybrids
39. V.M.D.-Visual molecular dynamics
40. RasMol: Biomolecular graphics for all
41. SWISS-MODEL and the Swiss-PdbViewer: An environment for comparative protein modeling
42. Raster3D: Photorealistic molecular graphics