The γ-secretase blocker DAPT impairs recovery from lipopolysaccharide-induced inflammation in rat brain

Neuroscience

Volumn 210, Issue , 2012, Pages 99-109

  Nasoohi, S ^a,b   Hemmati, A A ^a   Moradi, F ^b   Ahmadiani, A ^b  

^a AHVAZ JUNDISHAPUR UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

secretase; Acute neuroinflammation; Alzheimer disease; Notch receptor

Indexed keywords

CASPASE 3; CYCLOOXYGENASE 2; GAMMA SECRETASE; GAMMA SECRETASE INHIBITOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; N [N (3,5 DIFLUOROPHENACETYL)ALANYL]PHENYLGLYCINE TERT BUTYL ESTER; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ACUTE PHASE RESPONSE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; ENCEPHALITIS; ENZYME ACTIVITY; ENZYME INHIBITION; FLUOROMETRY; HYPERACTIVITY; IMMUNOREGULATION; MALE; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; RAT; SINGLE DRUG DOSE;

AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; BLOTTING, WESTERN; BRAIN; CYCLOOXYGENASE 2; ENZYME INHIBITORS; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; INFLAMMATION; LIPOPOLYSACCHARIDES; MALE; NF-KAPPA B; RATS; RATS, WISTAR; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84861200837     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2012.02.051     Document Type: Article

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