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Volumn 131, Issue 1-2, 2012, Pages 30-36

Progesterone inhibition of neuronal calcium signaling underlies aspects of progesterone-mediated neuroprotection

Author keywords

Brain Injury; Calcium; Excitotoxicity; Ischemia; Neuroprotection; Progesterone

Indexed keywords

2 (4 CHLOROPHENYL) 4 DIETHYLAMINOACETYL 2,3 DIHYDRO 4H 1,4 BENZOTHIAZINE; 4 [2 (4 ISOPROPYLBENZAMIDO)ETHOXY]BENZOIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR ALPHA4; AMLODIPINE; AMYLOID BETA PROTEIN; AZELNIDIPINE; BENIDIPINE; CALCIUM; CALCIUM CHANNEL L TYPE; EMOPAMIL; GLUTAMIC ACID; ION CHANNEL; MEXILETINE; NEUROPROTECTIVE AGENT; NEUROTRANSMITTER RECEPTOR; NIFEDIPINE; PHENYTOIN; PROGESTERONE; RILUZOLE; SODIUM CHANNEL; TETRODOTOXIN; UNCLASSIFIED DRUG; VOLTAGE GATED CALCIUM CHANNEL; VOLTAGE GATED POTASSIUM CHANNEL;

EID: 84861197164     PISSN: 09600760     EISSN: 18791220     Source Type: Journal    
DOI: 10.1016/j.jsbmb.2011.11.002     Document Type: Review
Times cited : (35)

References (97)
  • 1
    • 0025031767 scopus 로고
    • Effect of steroids on edema and sodium uptake of the brain during focal ischemia in rats
    • A.L. Betz, and H.C. Coester Effect of steroids on edema and sodium uptake of the brain during focal ischemia in rats Stroke 21 1990 1199 1204 (Pubitemid 20255417)
    • (1990) Stroke , vol.21 , Issue.8 , pp. 1199-1204
    • Betz, A.L.1    Coester, H.C.2
  • 2
    • 0030607198 scopus 로고    scopus 로고
    • Progesterone is neuroprotective after transient middle cerebral artery occlusion in male rats
    • DOI 10.1016/0006-8993(96)00605-1
    • N. Jiang, M. Chopp, D. Stein, and H. Feit Progesterone is neuroprotective after transient middle cerebral artery occlusion in male rats Brain Res. 735 1996 101 107 (Pubitemid 26336624)
    • (1996) Brain Research , vol.735 , Issue.1 , pp. 101-107
    • Jiang, N.1    Chopp, M.2    Stein, D.3    Feit, H.4
  • 3
    • 0036791875 scopus 로고    scopus 로고
    • Progesterone administration during reperfusion, but not preischemia alone, reduces injury in ovariectomized rats
    • S.J. Murphy, M.T. Littleton-Kearney, and P.D. Hurn Progesterone administration during reperfusion, but not preischemia alone, reduces injury in ovariectomized rats J. Cereb. Blood Flow Metab. 22 2002 1181 1188
    • (2002) J. Cereb. Blood Flow Metab. , vol.22 , pp. 1181-1188
    • Murphy, S.J.1    Littleton-Kearney, M.T.2    Hurn, P.D.3
  • 4
    • 19544385112 scopus 로고    scopus 로고
    • Post-ischemic administration of progesterone in rats exerts neuroprotective effects on the hippocampus
    • DOI 10.1016/j.neulet.2005.03.066, PII S0304394005003241
    • G. Morali, G. Letechipia-Vallejo, E. Lopez-Loeza, P. Montes, L. Hernandez-Morales, and M. Cervantes Post-ischemic administration of progesterone in rats exerts neuroprotective effects on the hippocampus Neurosci. Lett. 382 2005 286 290 (Pubitemid 40733637)
    • (2005) Neuroscience Letters , vol.382 , Issue.3 , pp. 286-290
    • Morali, G.1    Letechipia-Vallejo, G.2    Lopez-Loeza, E.3    Montes, P.4    Hernandez-Morales, L.5    Cervantes, M.6
  • 5
    • 3042773856 scopus 로고    scopus 로고
    • Progesterone enhances functional recovery after middle cerebral artery occlusion in male mice
    • C.L. Gibson, and S.P. Murphy Progesterone enhances functional recovery after middle cerebral artery occlusion in male mice J. Cereb. Blood Flow Metab. 24 2004 805 813 (Pubitemid 38880226)
    • (2004) Journal of Cerebral Blood Flow and Metabolism , vol.24 , Issue.7 , pp. 805-813
    • Gibson, C.L.1    Murphy, S.P.2
  • 6
    • 33645002699 scopus 로고    scopus 로고
    • Allopregnanolone, a progesterone metabolite, is more effective than progesterone in reducing cortical infarct volume after transient middle cerebral artery occlusion
    • I. Sayeed, Q. Guo, S.W. Hoffman, and D.G. Stein Allopregnanolone, a progesterone metabolite, is more effective than progesterone in reducing cortical infarct volume after transient middle cerebral artery occlusion Ann. Emerg. Med. 47 2006 381 389
    • (2006) Ann. Emerg. Med. , vol.47 , pp. 381-389
    • Sayeed, I.1    Guo, Q.2    Hoffman, S.W.3    Stein, D.G.4
  • 7
    • 0032724682 scopus 로고    scopus 로고
    • Neuroprotective effects of progesterone after transient middle cerebral artery occlusion in rat
    • DOI 10.1016/S0022-510X(99)00247-6, PII S0022510X99002476
    • J. Chen, M. Chopp, and Y. Li Neuroprotective effects of progesterone after transient middle cerebral artery occlusion in rat J. Neurol. Sci. 171 1999 24 30 (Pubitemid 29525574)
    • (1999) Journal of the Neurological Sciences , vol.171 , Issue.1 , pp. 24-30
    • Chen, J.1    Chopp, M.2    Li, Y.3
  • 8
    • 0034016139 scopus 로고    scopus 로고
    • Neuroprotective effect of postischemic administration of progesterone in spontaneously hypertensive rats with focal cerebral ischemia
    • Y. Kumon, S.C. Kim, P. Tompkins, A. Stevens, S. Sakaki, and C.M. Loftus Neuroprotective effect of postischemic administration of progesterone in spontaneously hypertensive rats with focal cerebral ischemia J. Neurosurg. 92 2000 848 852 (Pubitemid 30243934)
    • (2000) Journal of Neurosurgery , vol.92 , Issue.5 , pp. 848-852
    • Kumon, Y.1    Kim, S.C.2    Tompkins, P.3    Stevens, A.4    Sakaki, S.5    Loftus, C.M.6
  • 9
    • 77249145948 scopus 로고    scopus 로고
    • Neuroprotective effects of progesterone following stroke in aged rats
    • J. Wang, C. Jiang, C. Liu, X. Li, N. Chen, and Y. Hao Neuroprotective effects of progesterone following stroke in aged rats Behav. Brain Res. 209 2010 119 122
    • (2010) Behav. Brain Res. , vol.209 , pp. 119-122
    • Wang, J.1    Jiang, C.2    Liu, C.3    Li, X.4    Chen, N.5    Hao, Y.6
  • 10
    • 34548089961 scopus 로고    scopus 로고
    • Progesterone inhibits ischemic brain injury in a rat model of permanent middle cerebral artery occlusion
    • I. Sayeed, B. Wali, and D.G. Stein Progesterone inhibits ischemic brain injury in a rat model of permanent middle cerebral artery occlusion Restor. Neurol. Neurosci. 25 2007 151 159 (Pubitemid 47290443)
    • (2007) Restorative Neurology and Neuroscience , vol.25 , Issue.2 , pp. 151-159
    • Sayeed, I.1    Wali, B.2    Stein, D.G.3
  • 11
    • 18144409121 scopus 로고    scopus 로고
    • Progesterone suppresses the inflammatory response and nitric oxide synthase-2 expression following cerebral ischemia
    • DOI 10.1016/j.expneurol.2005.01.009
    • C.L. Gibson, D. Constantin, M.J. Prior, P.M. Bath, and S.P. Murphy Progesterone suppresses the inflammatory response and nitric oxide synthase-2 expression following cerebral ischemia Exp. Neurol. 193 2005 522 530 (Pubitemid 40616199)
    • (2005) Experimental Neurology , vol.193 , Issue.2 , pp. 522-530
    • Gibson, C.L.1    Constantin, D.2    Prior, M.J.W.3    Bath, P.M.W.4    Murphy, S.P.5
  • 12
    • 63349089474 scopus 로고    scopus 로고
    • Effects of progesterone administration on infarct volume and functional deficits following permanent focal cerebral ischemia in rats
    • T. Ishrat, I. Sayeed, F. Atif, and D.G. Stein Effects of progesterone administration on infarct volume and functional deficits following permanent focal cerebral ischemia in rats Brain Res. 1257 2009 94 101
    • (2009) Brain Res. , vol.1257 , pp. 94-101
    • Ishrat, T.1    Sayeed, I.2    Atif, F.3    Stein, D.G.4
  • 13
    • 0027522598 scopus 로고
    • Gender influences outcome of brain injury: Progesterone plays a protective role
    • R.L. Roof, R. Duvdevani, and D.G. Stein Gender influences outcome of brain injury: progesterone plays a protective role Brain Res. 607 1993 333 336 (Pubitemid 23104985)
    • (1993) Brain Research , vol.607 , Issue.1-2 , pp. 333-336
    • Roof, R.L.1    Duvdevani, R.2    Stein, D.G.3
  • 14
    • 0029878565 scopus 로고    scopus 로고
    • Progesterone rapidly decreases brain edema: Treatment delayed up to 24 hours is still effective
    • DOI 10.1006/exnr.1996.0063
    • R.L. Roof, R. Duvdevani, J.W. Heyburn, and D.G. Stein Progesterone rapidly decreases brain edema: treatment delayed up to 24 h is still effective Exp. Neurol. 138 1996 246 251 (Pubitemid 26132712)
    • (1996) Experimental Neurology , vol.138 , Issue.2 , pp. 246-251
    • Roof, R.L.1    Duvdevani, R.2    Heyburn, J.W.3    Stein, D.G.4
  • 15
    • 0028072396 scopus 로고
    • Progesterone facilitates cognitive recovery an reduces secondary neuronal loss caused by cortical contusion injury in male rats
    • DOI 10.1006/exnr.1994.1147
    • R.L. Roof, R. Duvdevani, L. Braswell, and D.G. Stein Progesterone facilitates cognitive recovery and reduces secondary neuronal loss caused by cortical contusion injury in male rats Exp. Neurol. 129 1994 64 69 (Pubitemid 24344157)
    • (1994) Experimental Neurology , vol.129 , Issue.1 , pp. 64-69
    • Roof, R.L.1    Duvdevani, R.2    Braswell, L.3    Stein, D.G.4
  • 16
    • 0036444181 scopus 로고    scopus 로고
    • Progesterone protects against necrotic damage and behavioral abnormalities caused by traumatic brain injury
    • DOI 10.1006/exnr.2002.8020
    • D.A. Shear, R. Galani, S.W. Hoffman, and D.G. Stein Progesterone protects against necrotic damage and behavioral abnormalities caused by traumatic brain injury Exp. Neurol. 178 2002 59 67 (Pubitemid 35425609)
    • (2002) Experimental Neurology , vol.178 , Issue.1 , pp. 59-67
    • Shear, D.A.1    Galani, R.2    Hoffman, S.W.3    Stein, D.G.4
  • 17
    • 0347418151 scopus 로고    scopus 로고
    • Allopregnanolone and progesterone decrease cell death and cognitive deficits after a contusion of the rat pre-frontal cortex
    • DOI 10.1016/j.neuroscience.2003.09.023
    • M. Djebaili, S.W. Hoffman, and D.G. Stein Allopregnanolone and progesterone decrease cell death and cognitive deficits after a contusion of the rat pre-frontal cortex Neuroscience 123 2004 349 359 (Pubitemid 38035216)
    • (2004) Neuroscience , vol.123 , Issue.2 , pp. 349-359
    • Djebaili, M.1    Hoffman, S.W.2    Stein, D.G.3
  • 18
    • 34247251994 scopus 로고    scopus 로고
    • Effects of progesterone on neurologic and morphologic outcome following diffuse traumatic brain injury in rats
    • DOI 10.1016/j.expneurol.2007.01.034, PII S0014488607000507
    • C.A. O'Connor, I. Cernak, F. Johnson, and R. Vink Effects of progesterone on neurologic and morphologic outcome following diffuse traumatic brain injury in rats Exp. Neurol. 205 2007 145 153 (Pubitemid 46617501)
    • (2007) Experimental Neurology , vol.205 , Issue.1 , pp. 145-153
    • O'Connor, C.A.1    Cernak, I.2    Johnson, F.3    Vink, R.4
  • 19
    • 12544255204 scopus 로고    scopus 로고
    • The neurosteroids progesterone and allopregnanolone reduce cell death, gliosis, and functional deficits after traumatic brain injury in rats
    • M. Djebaili, Q. Guo, E.H. Pettus, S.W. Hoffman, and D.G. Stein The neurosteroids progesterone and allopregnanolone reduce cell death, gliosis, and functional deficits after traumatic brain injury in rats J. Neurotrauma 22 2005 106 118
    • (2005) J. Neurotrauma , vol.22 , pp. 106-118
    • Djebaili, M.1    Guo, Q.2    Pettus, E.H.3    Hoffman, S.W.4    Stein, D.G.5
  • 20
    • 18444383966 scopus 로고    scopus 로고
    • The neuroprotective effect of progesterone after traumatic brain injury in male mice is independent of both the inflammatory response and growth factor expression
    • DOI 10.1111/j.1460-9568.2005.03995.x
    • N.C. Jones, D. Constantin, M.J. Prior, P.G. Morris, C.A. Marsden, and S. Murphy The neuroprotective effect of progesterone after traumatic brain injury in male mice is independent of both the inflammatory response and growth factor expression Eur. J. Neurosci. 21 2005 1547 1554 (Pubitemid 40646600)
    • (2005) European Journal of Neuroscience , vol.21 , Issue.6 , pp. 1547-1554
    • Jones, N.C.1    Constantin, D.2    Prior, M.J.W.3    Morris, P.G.4    Marsden, C.A.5    Murphy, S.6
  • 21
    • 0142195893 scopus 로고    scopus 로고
    • Behavioral effects and anatomic correlates after brain injury: A progesterone dose-response study
    • DOI 10.1016/j.pbb.2003.07.003
    • C.W. Goss, S.W. Hoffman, and D.G. Stein Behavioral effects and anatomic correlates after brain injury: a progesterone dose-response study Pharmacol. Biochem. Behav. 76 2003 231 242 (Pubitemid 37329844)
    • (2003) Pharmacology Biochemistry and Behavior , vol.76 , Issue.2 , pp. 231-242
    • Goss, C.W.1    Hoffman, S.W.2    Stein, D.G.3
  • 22
    • 0033570133 scopus 로고    scopus 로고
    • Progesterone is neuroprotective after acute experimental spinal cord trauma in rats
    • DOI 10.1097/00007632-199910150-00013
    • A.J. Thomas, R.P. Nockels, H.Q. Pan, C.I. Shaffrey, and M. Chopp Progesterone is neuroprotective after acute experimental spinal cord trauma in rats Spine 24 1999 2134 2138 (Phila Pa 1976) (Pubitemid 29489429)
    • (1999) Spine , vol.24 , Issue.20 , pp. 2134-2138
    • Thomas, A.J.1    Nockels, R.P.2    Pan, H.Q.3    Shaffrey, C.I.4    Chopp, M.5
  • 23
    • 70149092981 scopus 로고    scopus 로고
    • Progesterone with vitamin D affords better neuroprotection against excitotoxicity in cultured cortical neurons than progesterone alone
    • F. Atif, I. Sayeed, T. Ishrat, and D.G. Stein Progesterone with vitamin D affords better neuroprotection against excitotoxicity in cultured cortical neurons than progesterone alone J. Mol. Med. 15 2009 328 336
    • (2009) J. Mol. Med. , vol.15 , pp. 328-336
    • Atif, F.1    Sayeed, I.2    Ishrat, T.3    Stein, D.G.4
  • 24
    • 0027249424 scopus 로고
    • Steroid hormones protect spinal cord neurons from glutamate toxicity
    • DOI 10.1016/0306-4522(93)90513-F
    • T. Ogata, Y. Nakamura, K. Tsuji, T. Shibata, and K. Kataoka Steroid hormones protect spinal cord neurons from glutamate toxicity Neuroscience 55 1993 445 449 (Pubitemid 23211356)
    • (1993) Neuroscience , vol.55 , Issue.2 , pp. 445-449
    • Ogata, T.1    Nakamura, Y.2    Tsui, K.3    Shibata, T.4    Kataoka, K.5
  • 25
    • 0029924284 scopus 로고    scopus 로고
    • Estrogens attenuate and corticosterone exacerbates excitotoxicity, oxidative injury, and amyloid β-peptide toxicity in hippocampal neurons
    • Y. Goodman, A.J. Bruce, B. Cheng, and M.P. Mattson Estrogens attenuate and corticosterone exacerbates excitotoxicity, oxidative injury, and amyloid beta-peptide toxicity in hippocampal neurons J. Neurochem. 66 1996 1836 1844 (Pubitemid 26118770)
    • (1996) Journal of Neurochemistry , vol.66 , Issue.5 , pp. 1836-1844
    • Goodman, Y.1    Bruce, A.J.2    Cheng, B.3    Mattson, M.P.4
  • 26
    • 0042337371 scopus 로고    scopus 로고
    • Divergent impact of progesterone and medroxyprogesterone acetate (Provera) on nuclear mitogen-activated protein kinase signaling
    • DOI 10.1073/pnas.1334098100
    • J. Nilsen, and R.D. Brinton Divergent impact of progesterone and medroxyprogesterone acetate (Provera) on nuclear mitogen-activated protein kinase signaling Proc. Natl. Acad. Sci. U.S.A. 100 2003 10506 10511 (Pubitemid 37071908)
    • (2003) Proceedings of the National Academy of Sciences of the United States of America , vol.100 , Issue.18 , pp. 10506-10511
    • Nilsen, J.1    Brinton, R.D.2
  • 27
    • 67349281933 scopus 로고    scopus 로고
    • Oestrogen and progestins differently prevent glutamate toxicity in cortical neurons depending on prior hormonal exposure via the induction of neural nitric oxide synthase
    • P. Mannella, A.M. Sanchez, M.S. Giretti, A.R. Genazzani, and T. Simoncini Oestrogen and progestins differently prevent glutamate toxicity in cortical neurons depending on prior hormonal exposure via the induction of neural nitric oxide synthase Steroids 74 2009 650 656
    • (2009) Steroids , vol.74 , pp. 650-656
    • Mannella, P.1    Sanchez, A.M.2    Giretti, M.S.3    Genazzani, A.R.4    Simoncini, T.5
  • 28
    • 79959870181 scopus 로고    scopus 로고
    • Progesterone inhibition of voltage-gated calcium channels is a potential neuroprotective mechanism against excitotoxicity
    • J.I. Luoma, B.G. Kelley, and P.G. Mermelstein Progesterone inhibition of voltage-gated calcium channels is a potential neuroprotective mechanism against excitotoxicity Steroids 2011
    • (2011) Steroids
    • Luoma, J.I.1    Kelley, B.G.2    Mermelstein, P.G.3
  • 29
    • 67649664596 scopus 로고    scopus 로고
    • The differences in neuroprotective efficacy of progesterone and medroxyprogesterone acetate correlate with their effects on brain-derived neurotrophic factor expression
    • P.K. Jodhka, P. Kaur, W. Underwood, J.P. Lydon, and M. Singh The differences in neuroprotective efficacy of progesterone and medroxyprogesterone acetate correlate with their effects on brain-derived neurotrophic factor expression Endocrinology 150 2009 3162 3168
    • (2009) Endocrinology , vol.150 , pp. 3162-3168
    • Jodhka, P.K.1    Kaur, P.2    Underwood, W.3    Lydon, J.P.4    Singh, M.5
  • 30
    • 34547622839 scopus 로고    scopus 로고
    • Progesterone increases brain-derived neurotrophic factor expression and protects against glutamate toxicity in a mitogen-activated protein kinase- and phosphoinositide-3 kinase-dependent manner in cerebral cortical explants
    • DOI 10.1002/jnr.21370
    • P. Kaur, P.K. Jodhka, W.A. Underwood, C.A. Bowles, N.C. de Fiebre, C.M. de Fiebre, and M. Singh Progesterone increases brain-derived neuroptrophic factor expression and protects against glutamate toxicity in a mitogen-activated protein kinase- and phosphoinositide-3 kinase-dependent manner in cerebral cortical explants J. Neurosci. Res. 85 2007 2441 2449 (Pubitemid 47204758)
    • (2007) Journal of Neuroscience Research , vol.85 , Issue.11 , pp. 2441-2449
    • Kaur, P.1    Jodhka, P.K.2    Underwood, W.A.3    Bowles, C.A.4    De Fiebre, N.C.5    De Fiebre, C.M.6    Singh, M.7
  • 31
    • 70350452763 scopus 로고    scopus 로고
    • Progesterone BDNF and neuroprotection in the injured CNS
    • T. Coughlan, C. Gibson, S. Murphy, and Progesterone BDNF and neuroprotection in the injured CNS Int. J. Neurosci. 119 2009 1718 1740
    • (2009) Int. J. Neurosci. , vol.119 , pp. 1718-1740
    • Coughlan, T.1    Gibson, C.2    Murphy, S.3
  • 32
    • 0034743548 scopus 로고    scopus 로고
    • Neuroprotective properties of 17beta-estradiol, progesterone, and raloxifene in MPTP C57Bl/6 mice
    • S. Callier, M. Morissette, M. Grandbois, D. Pelaprat, and T. Di Paolo Neuroprotective properties of 17beta-estradiol, progesterone, and raloxifene in MPTP C57Bl/6 mice Synapse 41 2001 131 138
    • (2001) Synapse , vol.41 , pp. 131-138
    • Callier, S.1    Morissette, M.2    Grandbois, M.3    Pelaprat, D.4    Di Paolo, T.5
  • 35
    • 43249131666 scopus 로고    scopus 로고
    • Improved outcomes from the administration of progesterone for patients with acute severe traumatic brain injury: A randomized controlled trial
    • G. Xiao, J. Wei, W. Yan, W. Wang, and Z. Lu Improved outcomes from the administration of progesterone for patients with acute severe traumatic brain injury: a randomized controlled trial Crit. Care 12 2008 R61
    • (2008) Crit. Care , vol.12 , pp. 61
    • Xiao, G.1    Wei, J.2    Yan, W.3    Wang, W.4    Lu, Z.5
  • 36
    • 0031720131 scopus 로고    scopus 로고
    • Female TBI patients recover better than males
    • DOI 10.1080/026990598122197
    • Z. Groswasser, M. Cohen, and O. Keren Female TBI patients recover better than males Brain Injury 12 1998 805 808 (Pubitemid 28425306)
    • (1998) Brain Injury , vol.12 , Issue.9 , pp. 805-808
    • Groswasser, Z.1    Cohen, M.2    Keren, O.3
  • 37
    • 0026690043 scopus 로고
    • Progesterone treatment attenuates brain edema following contusion injury in male and female rats
    • R.L. Roof, R. Duvdevani, and D. Stein Progesterone treatment attenuates brain edema following contusion injury in male and female rats Restorative neurology and neuroscience 4 1992 425 427 (Pubitemid 23001029)
    • (1992) Restorative Neurology and Neuroscience , vol.4 , Issue.6 , pp. 425-427
    • Roof, R.L.1    Duvdevani, R.2    Stein, D.G.3
  • 38
    • 20544436716 scopus 로고    scopus 로고
    • Lack of a gender difference in post-traumatic neurodegeneration in the mouse controlled cortical impact injury model
    • DOI 10.1089/neu.2005.22.669
    • E.D. Hall, T.R. Gibson, and K.M. Pavel Lack of a gender difference in post-traumatic neurodegeneration in the mouse controlled cortical impact injury model J. Neurotrauma 22 2005 669 679 (Pubitemid 40840382)
    • (2005) Journal of Neurotrauma , vol.22 , Issue.6 , pp. 669-679
    • Hall, E.D.1    Gibson, T.R.2    Pavel, K.M.3
  • 40
    • 0024414966 scopus 로고
    • Neurosteroids: Biosynthesis of pregnenolone and progesterone in primary cultures of rat glial cells
    • I. Jung-Testas, Z.Y. Hu, E.E. Baulieu, and P. Robel Neurosteroids: biosynthesis of pregnenolone and progesterone in primary cultures of rat glial cells Endocrinology 125 1989 2083 2091 (Pubitemid 19258646)
    • (1989) Endocrinology , vol.125 , Issue.4 , pp. 2083-2091
    • Jung-Testas, L.1    Hu, Z.Y.2    Baulieu, E.E.3    Robel, P.4
  • 41
    • 70349976010 scopus 로고    scopus 로고
    • Combined 17beta-oestradiol and progesterone treatment prevents neuronal cell injury in cortical but not midbrain neurones or neuroblastoma cells
    • L. Lorenz, J. Dang, M. Misiak, A. Tameh Abolfazl, C. Beyer, and M. Kipp Combined 17beta-oestradiol and progesterone treatment prevents neuronal cell injury in cortical but not midbrain neurones or neuroblastoma cells J. Neuroendocrinol. 21 2009 841 849
    • (2009) J. Neuroendocrinol. , vol.21 , pp. 841-849
    • Lorenz, L.1    Dang, J.2    Misiak, M.3    Tameh Abolfazl, A.4    Beyer, C.5    Kipp, M.6
  • 42
    • 79952313963 scopus 로고    scopus 로고
    • Estrogen protection against mitochondrial toxin-induced cell death in hippocampal neurons: Antagonism by progesterone
    • J. Yao, S. Chen, E. Cadenas, and R.D. Brinton Estrogen protection against mitochondrial toxin-induced cell death in hippocampal neurons: antagonism by progesterone Brain Res. 1379 2011 2 10
    • (2011) Brain Res. , vol.1379 , pp. 2-10
    • Yao, J.1    Chen, S.2    Cadenas, E.3    Brinton, R.D.4
  • 43
    • 78149265595 scopus 로고    scopus 로고
    • Progesterone inhibits estrogen-mediated neuroprotection against excitotoxicity by down-regulating estrogen receptor-beta
    • C. Aguirre, A. Jayaraman, C. Pike, and M. Baudry Progesterone inhibits estrogen-mediated neuroprotection against excitotoxicity by down-regulating estrogen receptor-beta J. Neurochem. 115 2010 1277 1287
    • (2010) J. Neurochem. , vol.115 , pp. 1277-1287
    • Aguirre, C.1    Jayaraman, A.2    Pike, C.3    Baudry, M.4
  • 45
    • 55749111967 scopus 로고    scopus 로고
    • The combined effect of calcium channel blocker Lercanidipine and antioxidants on low-grade systemic inflammation parameters in essential hypertension patients
    • R. Farah, and R. Shurtz-Swirski The combined effect of calcium channel blocker Lercanidipine and antioxidants on low-grade systemic inflammation parameters in essential hypertension patients Minerva Cardioangiol. 56 2008 467 476
    • (2008) Minerva Cardioangiol. , vol.56 , pp. 467-476
    • Farah, R.1    Shurtz-Swirski, R.2
  • 46
    • 0026520595 scopus 로고
    • Effects of calcium channel blockers on formalin-induced nociception and inflammation in rats
    • H. Gurdal, Y. Sara, and F.C. Tulunay Effects of calcium channel blockers on formalin-induced nociception and inflammation in rats Pharmacology 44 1992 290 296
    • (1992) Pharmacology , vol.44 , pp. 290-296
    • Gurdal, H.1    Sara, Y.2    Tulunay, F.C.3
  • 47
    • 0026784244 scopus 로고
    • Protective effect of benidipine against the development of glomerular sclerosis in experimental nephrotic syndrome
    • S. Shirakura, J. Sano, A. Karasawa, and K. Kubo Protective effect of benidipine against the development of glomerular sclerosis in experimental nephrotic syndrome Jpn. J. Pharmacol. 59 1992 461 467
    • (1992) Jpn. J. Pharmacol. , vol.59 , pp. 461-467
    • Shirakura, S.1    Sano, J.2    Karasawa, A.3    Kubo, K.4
  • 48
    • 35148844253 scopus 로고    scopus 로고
    • Prevention of neuronal damage by calcium channel blockers with antioxidative effects after transient focal ischemia in rats
    • DOI 10.1016/j.brainres.2007.07.038, PII S0006899307016514
    • V. Lukic-Panin, T. Kamiya, H. Zhang, T. Hayashi, A. Tsuchiya, Y. Sehara, K. Deguchi, T. Yamashita, and K. Abe Prevention of neuronal damage by calcium channel blockers with antioxidative effects after transient focal ischemia in rats Brain Res. 1176 2007 143 150 (Pubitemid 47553120)
    • (2007) Brain Research , vol.1176 , Issue.1 , pp. 143-150
    • Lukic-Panin, V.1    Kamiya, T.2    Zhang, H.3    Hayashi, T.4    Tsuchiya, A.5    Sehara, Y.6    Deguchi, K.7    Yamashita, T.8    Abe, K.9
  • 49
    • 0035951623 scopus 로고    scopus 로고
    • 2+ channel blocker NS-7. I. Effect on the cerebral infarction and edema at the acute stage of permanent middle cerebral artery occlusion in rats
    • DOI 10.1016/S0006-8993(00)03167-X, PII S000689930003167X
    • Y. Aoki, M. Tamura, Y. Itoh, and Y. Ukai Cerebroprotective action of a Na+/Ca2+ channel blocker NS-7. I. Effect on the cerebral infarction and edema at the acute stage of permanent middle cerebral artery occlusion in rats Brain Res. 890 2001 162 169 (Pubitemid 32119535)
    • (2001) Brain Research , vol.890 , Issue.1 , pp. 162-169
    • Aoki, Y.1    Tamura, M.2    Itoh, Y.3    Ukai, Y.4
  • 50
    • 0032586016 scopus 로고    scopus 로고
    • 2+ channel blocker, T-477, prevents brain edema following microsphere-induced permanent occlusion of cerebral arterioles in rats
    • DOI 10.1254/jjp.81.170
    • K. Okuyama, S. Kiuchi, M. Okamoto, H. Narita, and Y. Kudo A novel Na+ and Ca2+ channel blocker, T-477, prevents brain edema following microsphere-induced permanent occlusion of cerebral arterioles in rats Jpn. J. Pharmacol. 81 1999 170 175 (Pubitemid 29532975)
    • (1999) Japanese Journal of Pharmacology , vol.81 , Issue.2 , pp. 170-175
    • Okuyama, K.1    Kiuchi, S.2    Okamoto, M.3    Narita, H.4    Kudo, Y.5
  • 51
    • 0026785258 scopus 로고
    • Evaluation of a novel calcium channel blocker, (S)-emopamil, on regional cerebral edema and neurobehavioral function after experimental brain injury
    • K. Okiyama, D.H. Smith, M.J. Thomas, and T.K. McIntosh Evaluation of a novel calcium channel blocker, (S)-emopamil, on regional cerebral edema and neurobehavioral function after experimental brain injury J. Neurosurg. 77 1992 607 615
    • (1992) J. Neurosurg. , vol.77 , pp. 607-615
    • Okiyama, K.1    Smith, D.H.2    Thomas, M.J.3    McIntosh, T.K.4
  • 52
    • 33846338047 scopus 로고    scopus 로고
    • Effect of progesterone on cerebral cortex edema in rats exposed to focal ischemia/reperfusion
    • D.L. Li, H.G. Zhao, D.X. Wang, and Y.F. Ding Effect of progesterone on cerebral cortex edema in rats exposed to focal ischemia/reperfusion Zhongguo Ying Yong Sheng Li Xue Za Zhi 17 2001 327 329
    • (2001) Zhongguo Ying Yong Sheng Li Xue Za Zhi , vol.17 , pp. 327-329
    • Li, D.L.1    Zhao, H.G.2    Wang, D.X.3    Ding, Y.F.4
  • 53
    • 33645747664 scopus 로고    scopus 로고
    • Progesterone administration modulates AQP4 expression and edema after traumatic brain injury in male rats
    • Q. Guo, I. Sayeed, L.M. Baronne, S.W. Hoffman, R. Guennoun, and D.G. Stein Progesterone administration modulates AQP4 expression and edema after traumatic brain injury in male rats Exp. Neurol. 198 2006 469 478
    • (2006) Exp. Neurol. , vol.198 , pp. 469-478
    • Guo, Q.1    Sayeed, I.2    Baronne, L.M.3    Hoffman, S.W.4    Guennoun, R.5    Stein, D.G.6
  • 54
    • 27744442689 scopus 로고    scopus 로고
    • Both estrogen and progesterone attenuate edema formation following diffuse traumatic brain injury in rats
    • DOI 10.1016/j.brainres.2005.09.011, PII S000689930501320X
    • C.A. O'Connor, I. Cernak, and R. Vink Both estrogen and progesterone attenuate edema formation following diffuse traumatic brain injury in rats Brain Res. 1062 2005 171 174 (Pubitemid 41613879)
    • (2005) Brain Research , vol.1062 , Issue.1-2 , pp. 171-174
    • O'Connor, C.A.1    Cernak, I.2    Vink, R.3
  • 55
    • 0034850817 scopus 로고    scopus 로고
    • Serum progesterone levels correlate with decreased cerebral edema after traumatic brain injury in male rats
    • D.W. Wright, M.E. Bauer, S.W. Hoffman, and D.G. Stein Serum progesterone levels correlate with decreased cerebral edema after traumatic brain injury in male rats J. Neurotrauma 18 2001 901 909 (Pubitemid 32852891)
    • (2001) Journal of Neurotrauma , vol.18 , Issue.9 , pp. 901-909
    • Wright, D.W.1    Bauer, M.E.2    Hoffman, S.W.3    Stein, D.G.4
  • 56
    • 4544282704 scopus 로고    scopus 로고
    • Progesterone and allopregnanolone reduce inflammatory cytokines after traumatic brain injury
    • DOI 10.1016/j.expneurol.2004.06.008, PII S0014488604002390
    • J. He, C.O. Evans, S.W. Hoffman, N.M. Oyesiku, and D.G. Stein Progesterone and allopregnanolone reduce inflammatory cytokines after traumatic brain injury Exp. Neurol. 189 2004 404 412 (Pubitemid 39221832)
    • (2004) Experimental Neurology , vol.189 , Issue.2 , pp. 404-412
    • He, J.1    Evans, C.-O.2    Hoffman, S.W.3    Oyesiku, N.M.4    Stein, D.G.5
  • 57
    • 20444477493 scopus 로고    scopus 로고
    • Progesterone treatment inhibits the inflammatory agents that accompany traumatic brain injury
    • DOI 10.1016/j.brainres.2005.05.004, PII S0006899305007158
    • E.H. Pettus, D.W. Wright, D.G. Stein, and S.W. Hoffman Progesterone treatment inhibits the inflammatory agents that accompany traumatic brain injury Brain Res. 1049 2005 112 119 (Pubitemid 40814581)
    • (2005) Brain Research , vol.1049 , Issue.1 , pp. 112-119
    • Pettus, E.H.1    Wright, D.W.2    Stein, D.G.3    Hoffman, S.W.4
  • 58
    • 37049023663 scopus 로고    scopus 로고
    • Inhibitory effect of progesterone on inflammatory factors after experimental traumatic brain injury
    • D.S. Pan, W.G. Liu, X.F. Yang, and F. Cao Inhibitory effect of progesterone on inflammatory factors after experimental traumatic brain injury Biomed. Environ. Sci. 20 2007 432 438 (Pubitemid 350247979)
    • (2007) Biomedical and Environmental Sciences , vol.20 , Issue.5 , pp. 432-438
    • Pan, D.-S.1    Liu, W.-G.2    Yang, X.-F.3    Cao, F.4
  • 59
    • 68449084536 scopus 로고    scopus 로고
    • Progesterone exerts neuroprotective effects by inhibiting inflammatory response after stroke
    • C. Jiang, J. Wang, X. Li, C. Liu, N. Chen, and Y. Hao Progesterone exerts neuroprotective effects by inhibiting inflammatory response after stroke Inflamm. Res. 58 2009 619 624
    • (2009) Inflamm. Res. , vol.58 , pp. 619-624
    • Jiang, C.1    Wang, J.2    Li, X.3    Liu, C.4    Chen, N.5    Hao, Y.6
  • 60
    • 33644912082 scopus 로고    scopus 로고
    • Progesterone increases the expression of myelin basic protein and the number of cells showing NG2 immunostaining in the lesioned spinal cord
    • F. Labombarda, S. Gonzalez, M.C. Gonzalez Deniselle, L. Garay, R. Guennoun, M. Schumacher, and A.F. De Nicola Progesterone increases the expression of myelin basic protein and the number of cells showing NG2 immunostaining in the lesioned spinal cord J. Neurotrauma 23 2006 181 192
    • (2006) J. Neurotrauma , vol.23 , pp. 181-192
    • Labombarda, F.1    Gonzalez, S.2    Gonzalez Deniselle, M.C.3    Garay, L.4    Guennoun, R.5    Schumacher, M.6    De Nicola, A.F.7
  • 63
    • 67649982189 scopus 로고    scopus 로고
    • Effects of progesterone on oligodendrocyte progenitors, oligodendrocyte transcription factors, and myelin proteins following spinal cord injury
    • F. Labombarda, S.L. Gonzalez, A. Lima, P. Roig, R. Guennoun, M. Schumacher, and A.F. de Nicola Effects of progesterone on oligodendrocyte progenitors, oligodendrocyte transcription factors, and myelin proteins following spinal cord injury Glia 57 2009 884 897
    • (2009) Glia , vol.57 , pp. 884-897
    • Labombarda, F.1    Gonzalez, S.L.2    Lima, A.3    Roig, P.4    Guennoun, R.5    Schumacher, M.6    De Nicola, A.F.7
  • 64
    • 3543068828 scopus 로고    scopus 로고
    • Calcium channel blockers ameliorate disease in a mouse model of multiple sclerosis
    • DOI 10.1016/j.expneurol.2004.05.023, PII S0014488604001980
    • E. Brand-Schieber, and P. Werner Calcium channel blockers ameliorate disease in a mouse model of multiple sclerosis Exp. Neurol. 189 2004 5 9 (Pubitemid 39024449)
    • (2004) Experimental Neurology , vol.189 , Issue.1 , pp. 5-9
    • Brand-Schieber, E.1    Werner, P.2
  • 65
    • 1442303796 scopus 로고    scopus 로고
    • An L-type calcium channel blocker, nimodipine influences trauma induced spinal cord conduction and axonal injury in the rat
    • T. Winkler, H.S. Sharma, E. Stalberg, R.D. Badgaiyan, T. Gordh, and J. Westman An L-type calcium channel blocker, nimodipine influences trauma induced spinal cord conduction and axonal injury in the rat Acta Neurochirurgica. Supplementum 86 2003 425 432
    • (2003) Acta Neurochirurgica. Supplementum , vol.86 , pp. 425-432
    • Winkler, T.1    Sharma, H.S.2    Stalberg, E.3    Badgaiyan, R.D.4    Gordh, T.5    Westman, J.6
  • 66
    • 1842558602 scopus 로고    scopus 로고
    • Molecular mechanisms of glutamate-dependent neurodegeneration in ischemia and traumatic brain injury
    • DOI 10.1007/s00018-003-3319-x
    • M. Arundine, and M. Tymianski Molecular mechanisms of glutamate-dependent neurodegeneration in ischemia and traumatic brain injury Cell. Mol. Life Sci. 61 2004 657 668 (Pubitemid 38446410)
    • (2004) Cellular and Molecular Life Sciences , vol.61 , Issue.6 , pp. 657-668
    • Arundine, M.1    Tymianski, M.2
  • 67
    • 0029130550 scopus 로고
    • Glutamate release and free radical production following brain injury: Effects of posttraumatic hypothermia
    • M.Y. Globus, O. Alonso, W.D. Dietrich, R. Busto, and M.D. Ginsberg Glutamate release and free radical production following brain injury: effects of posttraumatic hypothermia J. Neurochem. 65 1995 1704 1711
    • (1995) J. Neurochem. , vol.65 , pp. 1704-1711
    • Globus, M.Y.1    Alonso, O.2    Dietrich, W.D.3    Busto, R.4    Ginsberg, M.D.5
  • 68
    • 79959916506 scopus 로고    scopus 로고
    • Involvement of AMPA/kainate-excitotoxicity in MK801-induced neuronal death in the retrosplenial cortex
    • C. Bender, M. Rassetto, J.S. Olmos, S.D. Olmos, and A. Lorenzo Involvement of AMPA/kainate-excitotoxicity in MK801-induced neuronal death in the retrosplenial cortex Neuroscience 2009
    • (2009) Neuroscience
    • Bender, C.1    Rassetto, M.2    Olmos, J.S.3    Olmos, S.D.4    Lorenzo, A.5
  • 69
    • 0021961417 scopus 로고
    • Glutamate neurotoxicity in cortical cell culture is calcium dependent
    • DOI 10.1016/0304-3940(85)90069-2
    • D.W. Choi Glutamate neurotoxicity in cortical cell culture is calcium dependent Neurosci. Lett. 58 1985 293 297 (Pubitemid 15230671)
    • (1985) Neuroscience Letters , vol.58 , Issue.3 , pp. 293-297
    • Choi, D.W.1
  • 70
    • 0030015166 scopus 로고    scopus 로고
    • Normal and abnormal calcium homeostasis in neurons: A basis for the pathophysiology of traumatic and ischemic central nervous system injury
    • DOI 10.1097/00006123-199606000-00028
    • M. Tymianski, and C.H. Tator Normal and abnormal calcium homeostasis in neurons: a basis for the pathophysiology of traumatic and ischemic central nervous system injury Neurosurgery 38 1996 1176 1195 (Pubitemid 26162765)
    • (1996) Neurosurgery , vol.38 , Issue.6 , pp. 1176-1195
    • Tymianski, M.1    Tator, C.H.2
  • 72
    • 77549083577 scopus 로고    scopus 로고
    • Calcium, ischemia and excitotoxicity
    • K. Szydlowska, and M. Tymianski Calcium, ischemia and excitotoxicity Cell Calcium 47 2010 122 129
    • (2010) Cell Calcium , vol.47 , pp. 122-129
    • Szydlowska, K.1    Tymianski, M.2
  • 73
    • 77449136751 scopus 로고    scopus 로고
    • The effects of 17beta estradiol, 17alpha estradiol and progesterone on oxidative stress biomarkers in ovariectomized female rat brain subjected to global cerebral ischemia
    • V.H. Ozacmak, and H. Sayan The effects of 17beta estradiol, 17alpha estradiol and progesterone on oxidative stress biomarkers in ovariectomized female rat brain subjected to global cerebral ischemia Physiol. Res. 58 2009 909 912
    • (2009) Physiol. Res. , vol.58 , pp. 909-912
    • Ozacmak, V.H.1    Sayan, H.2
  • 74
    • 0033613884 scopus 로고    scopus 로고
    • Neuroprotective effects of a dihydropyridine derivative, 1,4-dihydro- 2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid methyl 6-(5- phenyl-3-pyrazolyloxy)hexyl ester (CV-159), on rat ischemic brain injury
    • DOI 10.1016/S0024-3205(99)00011-9, PII S0024320599000119
    • H. Miyazaki, S. Tanaka, Y. Fujii, K. Shimizu, K. Nagashima, M. Kamibayashi, T. Uehara, Y. Okuma, and Y. Nomura Neuroprotective effects of a dihydropyridine derivative, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5- pyridinedicarbox ylic acid methyl 6-(5-phenyl-3-pyrazolyloxy)hexyl ester (CV-159), on rat ischemic brain injury Life Sci. 64 1999 869 878 (Pubitemid 29100054)
    • (1999) Life Sciences , vol.64 , Issue.10 , pp. 869-878
    • Miyazaki, H.1    Tanaka, S.2    Fujii, Y.3    Shimizu, K.4    Nagashima, K.5    Kamibayashi, M.6    Uehara, T.7    Okuma, Y.8    Nomura, Y.9
  • 75
    • 67349144251 scopus 로고    scopus 로고
    • Estrogen attenuates glutamate-induced cell death by inhibiting Ca2+ influx through L-type voltage-gated Ca2+ channels
    • E.A. Sribnick, A.M. Del Re, S.K. Ray, J.J. Woodward, and N.L. Banik Estrogen attenuates glutamate-induced cell death by inhibiting Ca2+ influx through L-type voltage-gated Ca2+ channels Brain Res. 1276 2009 159 170
    • (2009) Brain Res. , vol.1276 , pp. 159-170
    • Sribnick, E.A.1    Del Re, A.M.2    Ray, S.K.3    Woodward, J.J.4    Banik, N.L.5
  • 76
    • 30344448016 scopus 로고    scopus 로고
    • Diltiazem-induced neuroprotection in glutamate excitotoxicity and ischemic insult of retinal neurons
    • DOI 10.1007/s10633-005-7341-1
    • G. Vallazza-Deschamps, C. Fuchs, D. Cia, L.H. Tessier, J.A. Sahel, H. Dreyfus, and S. Picaud Diltiazem-induced neuroprotection in glutamate excitotoxicity and ischemic insult of retinal neurons Doc. Ophthalmol. 110 2005 25 35 (Pubitemid 43064670)
    • (2005) Documenta Ophthalmologica , vol.110 , Issue.1 , pp. 25-35
    • Vallazza-Deschamps, G.1    Fuchs, C.2    Cia, D.3    Tessier, L.-H.4    Sahel, J.A.5    Dreyfus, H.6    Picaud, S.7
  • 77
    • 0023895160 scopus 로고
    • Characterization of R5020 and RU486 binding to progesterone receptor from calf uterus
    • C. Hurd, and V.K. Moudgil Characterization of R5020 and RU486 binding to progesterone receptor from calf uterus Biochemistry 27 1988 3618 3623
    • (1988) Biochemistry , vol.27 , pp. 3618-3623
    • Hurd, C.1    Moudgil, V.K.2
  • 78
    • 57449115128 scopus 로고    scopus 로고
    • Pregnenolone protects the PC-12 cell line against amyloid beta peptide toxicity but its sulfate ester does not
    • P. Akan, S. Kizildag, M. Ormen, S. Genc, M.A. Oktem, and M. Fadiloglu Pregnenolone protects the PC-12 cell line against amyloid beta peptide toxicity but its sulfate ester does not Chem. Biol. Interact. 177 2009 65 70
    • (2009) Chem. Biol. Interact. , vol.177 , pp. 65-70
    • Akan, P.1    Kizildag, S.2    Ormen, M.3    Genc, S.4    Oktem, M.A.5    Fadiloglu, M.6
  • 79
    • 20444446379 scopus 로고    scopus 로고
    • Pregnenolone sulphate attenuates AMPA cytotoxicity on rat cortical neurons
    • DOI 10.1111/j.1460-9568.2005.04079.x
    • H. Shirakawa, H. Katsuki, T. Kume, S. Kaneko, and A. Akaike Pregnenolone sulphate attenuates AMPA cytotoxicity on rat cortical neurons Eur. J. Neurosci. 21 2005 2329 2335 (Pubitemid 40813916)
    • (2005) European Journal of Neuroscience , vol.21 , Issue.9 , pp. 2329-2335
    • Shirakawa, H.1    Katsuki, H.2    Kume, T.3    Kaneko, S.4    Akaike, A.5
  • 80
    • 0032534523 scopus 로고    scopus 로고
    • Pregnenolone sulfate modulates NMDA receptors, inducing and potentiating acute excitotoxicity in isolated retina
    • DOI 10.1002/(SICI)1097-4547(19981215)54:6<787::AID-JNR6>3.0.CO;2-#
    • P. Guarneri, D. Russo, C. Cascio, G. De Leo, T. Piccoli, V. Sciuto, F. Piccoli, and R. Guarneri Pregnenolone sulfate modulates NMDA receptors, inducing and potentiating acute excitotoxicity in isolated retina J. Neurosci. Res. 54 1998 787 797 (Pubitemid 28544379)
    • (1998) Journal of Neuroscience Research , vol.54 , Issue.6 , pp. 787-797
    • Guarneri, P.1    Russo, D.2    Cascio, C.3    De Leo, G.4    Piccoli, T.5    Sciuto, V.6    Piccoli, F.7    Guarneri, R.8
  • 82
    • 71849101222 scopus 로고    scopus 로고
    • Allopregnanolone, the active metabolite of progesterone protects against neuronal damage in picrotoxin-induced seizure model in mice
    • S. Singh, D. Hota, A. Prakash, K.L. Khanduja, S.K. Arora, and A. Chakrabarti Allopregnanolone, the active metabolite of progesterone protects against neuronal damage in picrotoxin-induced seizure model in mice Pharmacol. Biochem. Behav. 94 2010 416 422
    • (2010) Pharmacol. Biochem. Behav. , vol.94 , pp. 416-422
    • Singh, S.1    Hota, D.2    Prakash, A.3    Khanduja, K.L.4    Arora, S.K.5    Chakrabarti, A.6
  • 83
    • 53749101000 scopus 로고    scopus 로고
    • Ischemic insult to cerebellar Purkinje cells causes diminished GABAA receptor function and allopregnanolone neuroprotection is associated with GABAA receptor stabilization
    • M.H. Kelley, N. Taguchi, A. Ardeshiri, M. Kuroiwa, P.D. Hurn, R.J. Traystman, and P.S. Herson Ischemic insult to cerebellar Purkinje cells causes diminished GABAA receptor function and allopregnanolone neuroprotection is associated with GABAA receptor stabilization J. Neurochem. 107 2008 668 678
    • (2008) J. Neurochem. , vol.107 , pp. 668-678
    • Kelley, M.H.1    Taguchi, N.2    Ardeshiri, A.3    Kuroiwa, M.4    Hurn, P.D.5    Traystman, R.J.6    Herson, P.S.7
  • 84
    • 80052378777 scopus 로고    scopus 로고
    • Progesterone blocks multiple routes of ion flux
    • B.G. Kelley, and P.G. Mermelstein Progesterone blocks multiple routes of ion flux Mol. Cell. Neurosci. 48 2011 137 141
    • (2011) Mol. Cell. Neurosci. , vol.48 , pp. 137-141
    • Kelley, B.G.1    Mermelstein, P.G.2
  • 85
    • 37049195180 scopus 로고
    • Additional steroids with luteoid activity
    • H. Selye, and G. Masson Additional steroids with luteoid activity Science 96 1942 358
    • (1942) Science , vol.96 , pp. 358
    • Selye, H.1    Masson, G.2
  • 87
    • 0028340051 scopus 로고
    • Effects of the sodium channel blocker tetrodotoxin (TTX) on cellular ion homeostasis in rat brain subjected to complete ischemia
    • DOI 10.1016/0006-8993(94)90230-5
    • Y. Xie, K. Dengler, E. Zacharias, B. Wilffert, and F. Tegtmeier Effects of the sodium channel blocker tetrodotoxin (TTX) on cellular ion homeostasis in rat brain subjected to complete ischemia Brain Res. 652 1994 216 224 (Pubitemid 24227275)
    • (1994) Brain Research , vol.652 , Issue.2 , pp. 216-224
    • Xie, Y.1    Dengler, K.2    Zacharias, E.3    Wilffert, B.4    Tegtmeier, F.5
  • 89
    • 0034665235 scopus 로고    scopus 로고
    • Broad-spectrum cation channel inhibition by LOE 908 MS reduces infarct volume in vivo and postmortem in focal cerebral ischemia in the rat
    • T. Tatlisumak, R.A. Carano, K. Takano, M.R. Meiler, F. Li, C.H. Sotak, D. Arndts, U. Pschorn, and M. Fisher Broad-spectrum cation channel inhibition by LOE 908 MS reduces infarct volume in vivo and postmortem in focal cerebral ischemia in the rat J. Neurol. Sci. 178 2000 107 113
    • (2000) J. Neurol. Sci. , vol.178 , pp. 107-113
    • Tatlisumak, T.1    Carano, R.A.2    Takano, K.3    Meiler, M.R.4    Li, F.5    Sotak, C.H.6    Arndts, D.7    Pschorn, U.8    Fisher, M.9
  • 91
    • 67349189879 scopus 로고    scopus 로고
    • Dihydropyridine block of voltage-dependent K+ currents in rat dorsal root ganglion neurons
    • X.L. Zhang, and M.S. Gold Dihydropyridine block of voltage-dependent K+ currents in rat dorsal root ganglion neurons Neuroscience 161 2009 184 194
    • (2009) Neuroscience , vol.161 , pp. 184-194
    • Zhang, X.L.1    Gold, M.S.2
  • 92
    • 0021930558 scopus 로고
    • The calcium channel blocker nitrendipine blocks sodium channels in neonatal rat cardiac myocytes
    • A. Yatani, and A.M. Brown The calcium channel blocker nitrendipine blocks sodium channels in neonatal rat cardiac myocytes Circ. Res. 56 1985 868 875 (Pubitemid 15231510)
    • (1985) Circulation Research , vol.56 , Issue.6 , pp. 868-875
    • Yatani, A.1    Brown, A.M.2
  • 94
    • 0030700570 scopus 로고    scopus 로고
    • Attenuation of brain injury and reduction of neuron-specific enolase by nicardipine in systemic circulation following focal ischemia and reperfusion in a rat model
    • M. Kittaka, S.L. Giannotta, V. Zelman, J.D. Correale, C.M. DeGiorgio, M.H. Weiss, and B.V. Zlokovic Attenuation of brain injury and reduction of neuron-specific enolase by nicardipine in systemic circulation following focal ischemia and reperfusion in a rat model J. Neurosurg. 87 1997 731 737 (Pubitemid 27454592)
    • (1997) Journal of Neurosurgery , vol.87 , Issue.5 , pp. 731-737
    • Kittaka, M.1    Giannotta, S.L.2    Zelman, V.3    Correale, J.D.4    DeGiorgio, C.M.5    Weiss, M.H.6    Zlokovic, B.V.7
  • 95
    • 48849089052 scopus 로고    scopus 로고
    • Neuroprotection for ischemic stroke: Past, present and future
    • M.D. Ginsberg Neuroprotection for ischemic stroke: past, present and future Neuropharmacology 55 2008 363 389
    • (2008) Neuropharmacology , vol.55 , pp. 363-389
    • Ginsberg, M.D.1
  • 96
    • 0028605632 scopus 로고
    • Dihydropyridine calcium antagonists and the trough: Peak ratio: Focus on adverse effects
    • (discussion S76-7)
    • M.G. Myers Dihydropyridine calcium antagonists and the trough: peak ratio: focus on adverse effects J. Hypertens. Suppl. 12 1994 S73 S76 (discussion S76-7)
    • (1994) J. Hypertens. Suppl. , vol.12
    • Myers, M.G.1
  • 97
    • 0034947146 scopus 로고    scopus 로고
    • Calcium channel blockers, postural vasoconstriction and dependent oedema in essential hypertension
    • DOI 10.1038/sj.jhh.1001201
    • R. Pedrinelli, G. Dell'Omo, and M. Mariani Calcium channel blockers, postural vasoconstriction and dependent oedema in essential hypertension J. Hum. Hypertens. 15 2001 455 461 (Pubitemid 32640260)
    • (2001) Journal of Human Hypertension , vol.15 , Issue.7 , pp. 455-461
    • Pedrinelli, R.1    Dell'Omo, G.2    Mariani, M.3


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