Progesterone inhibition of voltage-gated calcium channels is a potential neuroprotective mechanism against excitotoxicity

Steroids

Volumn 76, Issue 9, 2011, Pages 845-855

  Luoma, Jessie I ^a   Kelley, Brooke G ^a   Mermelstein, Paul G ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Brain injury; Calcium; Excitotoxicity; Glutamate; Ion channels; Neuroprotection

Indexed keywords

2 AMINO 5 PHOSPHONOVALERIC ACID; 3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; 6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; ANDROSTANOLONE; CALCIUM CHANNEL; CHOLESTEROL; CORTICOSTERONE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; ESTRADIOL; MESSENGER RNA; MIFEPRISTONE; N METHYL DEXTRO ASPARTIC ACID; NIFEDIPINE; PREGNENOLONE; PROGESTERONE; STEROID HORMONE; TRANSCRIPTION FACTOR NFAT; VOLTAGE GATED CALCIUM CHANNEL;

ANIMAL CELL; ARTICLE; BRAIN ELECTROPHYSIOLOGY; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CELL DEATH; CELL FUNCTION; CONTROLLED STUDY; DEPOLARIZATION; DRUG EFFECT; EXCITOTOXICITY; GENE EXPRESSION; IN VIVO STUDY; NERVE CELL; NEUROPROTECTION; NONHUMAN; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION;

6-CYANO-7-NITROQUINOXALINE-2,3-DIONE; ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID; ANIMALS; APOPTOSIS; BRAIN; BRAIN INJURIES; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS, L-TYPE; CALCIUM SIGNALING; CELLS, CULTURED; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; EXCITATORY AMINO ACID AGONISTS; EXCITATORY AMINO ACID ANTAGONISTS; FEMALE; GENE EXPRESSION; GENES, REPORTER; GLUTAMIC ACID; LUCIFERASES; MALE; MEMBRANE POTENTIALS; N-METHYLASPARTATE; NEURONS; NEUROPROTECTIVE AGENTS; NFATC TRANSCRIPTION FACTORS; NIFEDIPINE; POTASSIUM; PROGESTERONE; RATS; RATS, SPRAGUE-DAWLEY;

EID: 79959870181     PISSN: 0039128X     EISSN: 18785867     Source Type: Journal    
DOI: 10.1016/j.steroids.2011.02.013     Document Type: Article

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