Ischemic insult to cerebellar Purkinje cells causes diminished GABA A receptor function and allopregnanolone neuroprotection is associated with GABAA receptor stabilization

Journal of Neurochemistry

Volumn 107, Issue 3, 2008, Pages 668-678

  Kelley, Melissa H ^a   Taguchi, Noriko ^a   Ardeshiri, Ardalan ^a   Kuroiwa, Masayuki ^a   Hurn, Patricia D ^a   Traystman, Richard J ^a   Herson, Paco S ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

Allopregnanolone; Cerebellum; Excitotoxicity; GABAA receptor; Ischemia; Neuroprotection

Indexed keywords

3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; 4 AMINOBUTYRIC ACID A RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CEREBELLUM; CONTROLLED STUDY; EMBRYO; EXCITOTOXICITY; IMMUNOCYTOCHEMISTRY; IMMUNOREACTIVITY; IN VITRO STUDY; ISCHEMIA; NEUROPROTECTION; NONHUMAN; POSTSYNAPTIC POTENTIAL; PRIORITY JOURNAL; PURKINJE CELL; RAT;

ANIMALS; BLOTTING, WESTERN; BRAIN ISCHEMIA; IMMUNOHISTOCHEMISTRY; INHIBITORY POSTSYNAPTIC POTENTIALS; MICE; NEUROPROTECTIVE AGENTS; PATCH-CLAMP TECHNIQUES; PREGNANOLONE; PURKINJE CELLS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA-A; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

MUS;

EID: 53749101000     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2008.05617.x     Document Type: Article

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