Allopregnanolone, the active metabolite of progesterone protects against neuronal damage in picrotoxin-induced seizure model in mice

Pharmacology Biochemistry and Behavior

Volumn 94, Issue 3, 2010, Pages 416-422

  Singh, Surjit ^a   Hota, Debasish ^a   Prakash, Ajay ^a   Khanduja, Krishan L ^a   Arora, Sunil K ^a   Chakrabarti, Amitava ^a  

^a POSTGRADUATE INSTITUTE OF MEDICAL EDUCATION AND RESEARCH   (India)

Author keywords

5 reductase; Allopregnanolone picrotoxin; DNA fragmentation; Indomethacin; Progesterone; Seizures

Indexed keywords

3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; 5ALPHA PREGNANE 3,20 DIONE; CATALASE; DNA; FINASTERIDE; GLUTATHIONE PEROXIDASE; INDOMETACIN; LIPID; MALONALDEHYDE; PICROTOXIN; PROGESTERONE; SUPEROXIDE DISMUTASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICONVULSANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DNA FRAGMENTATION; DOSE RESPONSE; DRUG EFFICACY; LIPID BRAIN LEVEL; LIPID PEROXIDATION; MALE; MOUSE; NERVE INJURY; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; TONIC CLONIC SEIZURE;

ANIMALS; CONVULSANTS; DISEASE MODELS, ANIMAL; ELECTROPHORESIS, AGAR GEL; ENZYME INHIBITORS; FINASTERIDE; INDOMETHACIN; MALE; MICE; NEURONS; PICROTOXIN; PREGNANOLONE; SEIZURES;

MUS;

EID: 71849101222     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pbb.2009.10.003     Document Type: Article

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