-
1
-
-
0023105114
-
The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor
-
Kang J, Lemaire HG, Unterbeck A, Salbaum JM, Masters CL, Grzeschik KH, Multhaup G, Beyreuther K, Müller-Hill B (1987) The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor. Nature 325:19-25
-
(1987)
Nature
, vol.325
, pp. 19-25
-
-
Kang, J.1
Lemaire, H.G.2
Unterbeck, A.3
Salbaum, J.M.4
Masters, C.L.5
Grzeschik, K.H.6
Multhaup, G.7
Beyreuther, K.8
Müller-Hill, B.9
-
2
-
-
0024477047
-
695 precursor protein of Alzheimer's disease A4 amyloid is encoded by 16 exons
-
Lemaire HG, Salbaum JM, Multhaup G, Kang J, Bayney RM, Unterbeck A, Beyreuther K, Müller-Hill B (1989) The PreA4(695) precursor protein of Alzheimer's disease A4 amyloid is encoded by 16 exons. Nucleic Acids Res 17:517-522 (Pubitemid 19042292)
-
(1989)
Nucleic Acids Research
, vol.17
, Issue.2
, pp. 517-522
-
-
Lemaire, H.G.1
Salbaum, J.M.2
Multhaup, G.3
Kang, J.4
Bayney, R.M.5
Unterbeck, A.6
Beyreuther, K.7
Muller-Hill, B.8
-
3
-
-
0035816661
-
A transcriptivety active complex of APP with Fe65 and histone acetyltransferase Tip60
-
DOI 10.1126/science.1058783
-
Cao X, Südhof TC (2001) A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60. Science 29:115-120 (Pubitemid 32625507)
-
(2001)
Science
, vol.293
, Issue.5527
, pp. 115-120
-
-
Cao, X.1
Sudhof, T.C.2
-
4
-
-
0023872043
-
Novel precursor of Alzheimer's disase amyloid protein shows protease inhibitory activity
-
DOI 10.1038/331530a0
-
Kitaguchi N, Takahashi Y, Tokushima Y, Shiojiri S, Ito H (1988) Novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activity. Nature 331:530-532 (Pubitemid 18064377)
-
(1988)
Nature
, vol.331
, Issue.6156
, pp. 530-532
-
-
Kitaguchi, N.1
Takahashi, Y.2
Tokushima, Y.3
Shiojiri, S.4
Ito, H.5
-
5
-
-
0023850791
-
Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease
-
DOI 10.1038/331528a0
-
Tanzi RE, McClatchey AI, Lamperti ED, Villa-Komaroff L, Gusella JF, Neve RL (1988) Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzhei-mer's disease. Nature 331:528-530 (Pubitemid 18064376)
-
(1988)
Nature
, vol.331
, Issue.6156
, pp. 528-530
-
-
Tanzi, R.E.1
McClatchey, A.I.2
Lamperti, E.D.3
Villa-Komaroff, L.4
Gusella, J.F.5
Neve, R.L.6
-
6
-
-
0026442891
-
Identification of a mouse brain cDNA that encodes a protein related to the Alzheimer disease-associated amyloid beta protein precursor
-
Wasco W, Bupp K, Magendantz M, Gusella JF, Tanzi RE, Sol-omon F (1992) Identification of a mouse brain cDNA that encodes a protein related to the Alzheimer disease-associated amyloid beta protein precursor. Proc Natl Acad Sci USA 89:10758-10762
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 10758-10762
-
-
Wasco, W.1
Bupp, K.2
Magendantz, M.3
Gusella, J.F.4
Tanzi, R.E.5
Sol-Omon, F.6
-
7
-
-
0033972608
-
What the evolution of the amyloid protein precursor supergene family tells us about its function
-
DOI 10.1016/S0197-0186(99)00125-4, PII S0197018699001254
-
Coulson EJ, Paliga K, Beyreuther K, Masters CL (2000) What the evolution of the amyloid protein precursor supergene family tells us about its function. Neurochem Int 36:175-184 (Pubitemid 30047008)
-
(2000)
Neurochemistry International
, vol.36
, Issue.3
, pp. 175-184
-
-
Coulson, E.J.1
Paliga, K.2
Beyreuther, K.3
Masters, C.L.4
-
8
-
-
0035823495
-
Homo-dimerization of amyloid precursor protein and its implication in the amyloidogenic pathway of Alzheimer's disease
-
Scheuermann S, Hambsch B, Hesse L, Stumm J, Schmidt C, Beher D, Bayer TA, Beyreuther K, Multhaup G (2001) Homo-dimerization of amyloid precursor protein and its implication in the amyloidogenic pathway of Alzheimer's disease. J Biol Chem 276:33923-33929
-
(2001)
J Biol Chem
, vol.276
, pp. 33923-33929
-
-
Scheuermann, S.1
Hambsch, B.2
Hesse, L.3
Stumm, J.4
Schmidt, C.5
Beher, D.6
Bayer, T.A.7
Beyreuther, K.8
Multhaup, G.9
-
9
-
-
27144547977
-
Homo- and heterodimerization of APP family members promotes intercellular adhesion
-
DOI 10.1038/sj.emboj.7600824, PII 7600824
-
Soba P, Eggert S, Wagner K, Zentgraf H, Siehl K, Kreger S, Lower A, Langer A, Merdes G, Paro R, Masters CL, Muller U, Kins S, Beyreuther K (2005) Homo- and heterodimerization of APP family members promotes intercellular adhesion. EMBO J 24:3624-3634 (Pubitemid 41509369)
-
(2005)
EMBO Journal
, vol.24
, Issue.20
, pp. 3624-3634
-
-
Soba, P.1
Eggert, S.2
Wagner, K.3
Zentgraf, H.4
Siehl, K.5
Kreger, S.6
Lower, A.7
Langer, A.8
Merdes, G.9
Paro, R.10
Masters, C.L.11
Muller, U.12
Kins, S.13
Beyreuther, K.14
-
10
-
-
43749112022
-
Homophilic interactions of the amyloid precursor protein (APP) ectodomain are regulated by the loop region and affect beta-secretase cleavage of APP
-
Kaden D, Münter LM, Joshi M, Treiber C, Weise C, Bethge T, Voigt P, Schaefer M, Beyermann M, Reif B, Multhaup G (2008) Homophilic interactions of the amyloid precursor protein (APP) ectodomain are regulated by the loop region and affect beta-secretase cleavage of APP. J Biol Chem 283:7271-7279
-
(2008)
J Biol Chem
, vol.283
, pp. 7271-7279
-
-
Kaden, D.1
Münter, L.M.2
Joshi, M.3
Treiber, C.4
Weise, C.5
Bethge, T.6
Voigt, P.7
Schaefer, M.8
Beyermann, M.9
Reif, B.10
Multhaup, G.11
-
11
-
-
65249143369
-
Subcellular localization and dimerization of APLP1 are strikingly different from APP and APLP2
-
Kaden D, Voigt P, Munter LM, Bobowski KD, Schaefer M, Multhaup G (2009) Subcellular localization and dimerization of APLP1 are strikingly different from APP and APLP2. J Cell Sci 122:368-377
-
(2009)
J Cell Sci
, vol.122
, pp. 368-377
-
-
Kaden, D.1
Voigt, P.2
Munter, L.M.3
Bobowski, K.D.4
Schaefer, M.5
Multhaup, G.6
-
12
-
-
33947597857
-
GxxxG motifs within the amyloid precursor protein transmembrane sequence are critical for the etiology of Aβ42
-
DOI 10.1038/sj.emboj.7601616, PII 7601616
-
Munter LM, Voigt P, Harmeier A, Kaden D, Gottschalk KE, Weise C, Pipkorn R, Schaefer M, Langosch D, Multhaup G (2007) GxxxG motifs within the amyloid precursor protein transmembrane sequence are critical for the etiology of Abeta42. EMBO J 26:1702-1712 (Pubitemid 46480941)
-
(2007)
EMBO Journal
, vol.26
, Issue.6
, pp. 1702-1712
-
-
Munter, L.-M.1
Voigt, P.2
Harmeier, A.3
Kaden, D.4
Gottschalk, K.E.5
Weise, C.6
Pipkorn, R.7
Schaefer, M.8
Langosch, D.9
Multhaup, G.10
-
13
-
-
40549088246
-
Dimerization of the trans-membrane domain of amyloid precursor proteins and familial Alzheimer's disease mutants
-
Gorman PM, Kim S, Guo M, Melnyk RA, McLaurin J, Fraser PE, Bowie JU, Chakrabartty A (2008) Dimerization of the trans-membrane domain of amyloid precursor proteins and familial Alzheimer's disease mutants. BMC Neurosci 9:17-27
-
(2008)
BMC Neurosci
, vol.9
, pp. 17-27
-
-
Gorman, P.M.1
Kim, S.2
Guo, M.3
Melnyk, R.A.4
McLaurin, J.5
Fraser, P.E.6
Bowie, J.U.7
Chakrabartty, A.8
-
14
-
-
43149088724
-
Amyloidogenic processing but not amyloid precursor protein (APP) intracellular C-terminal domain pro-duction requires a precisely oriented APP dimer assembled by transmembrane GxxxG motifs
-
Kienlen-Campard P, Tasiaux B, Van Hees J, Li M, Huysseune S, Sato T, Fei JZ, Aimoto S, Courtoy PJ, Smith SO, Constantinescu SN, Octave JN (2008) Amyloidogenic processing but not amyloid precursor protein (APP) intracellular C-terminal domain pro-duction requires a precisely oriented APP dimer assembled by transmembrane GxxxG motifs. J Biol Chem 283:7733-7744
-
(2008)
J Biol Chem
, vol.283
, pp. 7733-7744
-
-
Kienlen-Campard, P.1
Tasiaux, B.2
Van Hees, J.3
Li, M.4
Huysseune, S.5
Sato, T.6
Fei, J.Z.7
Aimoto, S.8
Courtoy, P.J.9
Smith, S.O.10
Constantinescu, S.N.11
Octave, J.N.12
-
15
-
-
77954359268
-
Aberrant amyloid pre-cursor protein (APP) processing in hereditary forms of Alzheimer disease caused by APP familial Alzheimer disease mutations can be rescued by mutations in the APP GxxxG motif
-
Munter LM, Botev A, Richter L, Hildebrand PW, Althoff V, Weise C, Kaden D, Multhaup G (2010) Aberrant amyloid pre-cursor protein (APP) processing in hereditary forms of Alzheimer disease caused by APP familial Alzheimer disease mutations can be rescued by mutations in the APP GxxxG motif. J Biol Chem 285:21636-21643
-
(2010)
J Biol Chem
, vol.285
, pp. 21636-21643
-
-
Munter, L.M.1
Botev, A.2
Richter, L.3
Hildebrand, P.W.4
Althoff, V.5
Weise, C.6
Kaden, D.7
Multhaup, G.8
-
16
-
-
77957096840
-
Amyloid beta 42 peptide (Abeta42)-lowering compounds directly bind to Abeta and interfere with amyloid precursor protein (APP) transmembrane dimerization
-
Richter L, Munter LM, Ness J, Hildebrand PW, Dasari M, Un-terreitmeier S, Bulic B, Beyermann M, Gust R, Reif B, Weggen S, Langosch D, Multhaup G (2010) Amyloid beta 42 peptide (Abeta42)-lowering compounds directly bind to Abeta and interfere with amyloid precursor protein (APP) transmembrane dimerization. Proc Natl Acad Sci USA 107:14597-14602
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 14597-14602
-
-
Richter, L.1
Munter, L.M.2
Ness, J.3
Hildebrand, P.W.4
Dasari, M.5
Un-Terreitmeier, S.6
Bulic, B.7
Beyermann, M.8
Gust, R.9
Reif, B.10
Weggen, S.11
Langosch, D.12
Multhaup, G.13
-
17
-
-
70350350069
-
Induced dimerization of the amyloid precursor protein leads to decreased amyloid-beta protein production
-
Eggert S, Midthune B, Cottrell B, Koo EH (2009) Induced dimerization of the amyloid precursor protein leads to decreased amyloid-beta protein production. J Biol Chem 284:28943-28952
-
(2009)
J Biol Chem
, vol.284
, pp. 28943-28952
-
-
Eggert, S.1
Midthune, B.2
Cottrell, B.3
Koo, E.H.4
-
18
-
-
4143105782
-
The X-ray structure of an antiparallel dimer of the human amyloid precursor protein E2 domain
-
DOI 10.1016/j.molcel.2004.06.037, PII S109727650400379X
-
Wang Y, Ha Y (2004) The X-ray structure of an antiparallel dimer of the human amyloid precursor protein E2 domain. Mol Cell 15:343-353 (Pubitemid 39092751)
-
(2004)
Molecular Cell
, vol.15
, Issue.3
, pp. 343-353
-
-
Wang, Y.1
Ha, Y.2
-
19
-
-
33344458873
-
Solution conformation and heparin-induced dimerization of the full-length extracellular domain of the human amyloid precursor protein
-
DOI 10.1016/j.jmb.2005.12.053, PII S0022283605016293
-
Gralle M, Oliveira CL, Guerreiro LH, McKinstry WJ, Galatis D, Masters CL, Cappai R, Parker MW, Ramos CH, Torriani I, Ferreira ST (2006) Solution conformation and heparin-induced dimerization of the full-length extracellular domain of the human amyloid precursor protein. J Mol Biol 357:493-508 (Pubitemid 43290750)
-
(2006)
Journal of Molecular Biology
, vol.357
, Issue.2
, pp. 493-508
-
-
Gralle, M.1
Oliveira, C.L.P.2
Guerreiro, L.H.3
McKinstry, W.J.4
Galatis, D.5
Masters, C.L.6
Cappai, R.7
Parker, M.W.8
Ramos, C.H.I.9
Torriani, I.10
Ferreira, S.T.11
-
20
-
-
0024427039
-
Control of protein exit from the endoplasmic reticulum
-
Pelham HR (1989) Control of protein exit from the endoplasmic reticulum. Annu Rev Cell Biol 5:1-23 (Pubitemid 19286676)
-
(1989)
Annual Review of Cell Biology
, vol.5
, pp. 1-23
-
-
Pelham, H.R.B.1
-
21
-
-
0029778556
-
Signal-mediated sorting of membrane proteins between the endoplasmic reticulum and the Golgi apparatus
-
DOI 10.1146/annurev.cellbio.12.1.27
-
Teasdale RD, Jackson MR (1996) Signal-mediated sorting of membrane proteins between the endoplasmic reticulum and the Golgi apparatus. Annu Rev Cell Dev Biol 12:27-54 (Pubitemid 26422708)
-
(1996)
Annual Review of Cell and Developmental Biology
, vol.12
, pp. 27-54
-
-
Teasdale, R.D.1
Jackson, M.R.2
-
22
-
-
0033591357
-
Protein targeting to endoplasmic reticulum by dilysine signals involves direct reten-tion in addition to retrieval
-
Andersson H, Kappeler F, Hauri HP (1999) Protein targeting to endoplasmic reticulum by dilysine signals involves direct reten-tion in addition to retrieval. J Biol Chem 274:15080-15084
-
(1999)
J Biol Chem
, vol.274
, pp. 15080-15084
-
-
Andersson, H.1
Kappeler, F.2
Hauri, H.P.3
-
23
-
-
70450219526
-
Alpha-secretase mediated con-version of the amyloid precursor protein derived membrane stub C99 to C83 limits Abeta generation
-
Jager S, Leuchtenberger S, Martin A, Czirr E, Wesselowski J, Dieckmann M, Waldron E, Korth C, Koo EH, Heneka M, Weggen S, Pietrzik CU (2009) Alpha-secretase mediated con-version of the amyloid precursor protein derived membrane stub C99 to C83 limits Abeta generation. J Neurochem 111:1369-1382
-
(2009)
J Neurochem
, vol.111
, pp. 1369-1382
-
-
Jager, S.1
Leuchtenberger, S.2
Martin, A.3
Czirr, E.4
Wesselowski, J.5
Dieckmann, M.6
Waldron, E.7
Korth, C.8
Koo, E.H.9
Heneka, M.10
Weggen, S.11
Pietrzik, C.U.12
-
24
-
-
38749109672
-
GFP Reconstitution Across Synaptic Partners (GRASP) Defines Cell Contacts and Synapses in Living Nervous Systems
-
DOI 10.1016/j.neuron.2007.11.030, PII S0896627307010203
-
Feinberg EH, Vanhoven MK, Bendesky A, Wang G, Fetter RD, Shen K, Bargmann CI (2008) GFP Reconstitution Across Syn-aptic Partners (GRASP) defines cell contacts and synapses in living nervous systems. Neuron 57:353-363 (Pubitemid 351179161)
-
(2008)
Neuron
, vol.57
, Issue.3
, pp. 353-363
-
-
Feinberg, E.H.1
VanHoven, M.K.2
Bendesky, A.3
Wang, G.4
Fetter, R.D.5
Shen, K.6
Bargmann, C.I.7
-
25
-
-
0035128240
-
Expression of auxilin or AP180 inhibits endocytosis by mislocalizing clathrin: Evidence for formation of nascent pits containing AP1 or AP2 but not clathrin
-
Zhao X, Greener T, Al-Hasani H, Cushman SW, Eisenberg E, Greene LE (2001) Expression of auxilin or AP180 inhibits endocytosis by mislocalizing clathrin: evidence for formation of nascent pits containing AP1 or AP2 but not clathrin. J Cell Sci 114:353-365 (Pubitemid 32149577)
-
(2001)
Journal of Cell Science
, vol.114
, Issue.2
, pp. 353-365
-
-
Zhao, X.1
Greener, T.2
Al-Hasani, H.3
Cushman, S.W.4
Eisenberg, E.5
Greene, L.E.6
-
26
-
-
0035135419
-
2 and clathrin by AP180 in the nucleation of clathrin lattices on membranes
-
DOI 10.1126/science.291.5506.1051
-
Ford MG, Pearse BM, Higgins MK, Vallis Y, Owen DJ, Gibson A, Hopkins CR, Evans PR, McMahon HT (2001) Simultaneous binding ofPtdIns(4, 5)P2 and clathrin by AP180 in the nucleation of clathrin lattices on membranes. Science 291:1051-1055 (Pubitemid 32157415)
-
(2001)
Science
, vol.291
, Issue.5506
, pp. 1051-1055
-
-
Ford, M.G.J.1
Pearse, B.M.F.2
Higgins, M.K.3
Vallis, Y.4
Owen, D.J.5
Gibson, A.6
Hopkins, C.R.7
Evans, P.R.8
McMahon, H.T.9
-
27
-
-
0025989238
-
Multiple targets for brefeldin A
-
DOI 10.1016/0092-8674(91)90517-3
-
Pelham HR (1991) Multiple targets for brefeldin A. Cell 67:449-451 (Pubitemid 121001459)
-
(1991)
Cell
, vol.67
, Issue.3
, pp. 449-451
-
-
Pelham, H.R.B.1
-
28
-
-
0024237306
-
Brefeldin A causes disassembly of the Golgi complex and accumulation of secretory proteins in the endoplasmic reticulum
-
Fujiwara T, Oda K, Yokota S, Takatsuki A, Ikehara Y (1988) Brefeldin A causes disassembly of the Golgi complex and accumulation of secretory proteins in the endoplasmic reticulum. J Biol Chem 263:18545-18552 (Pubitemid 19005133)
-
(1988)
Journal of Biological Chemistry
, vol.263
, Issue.34
, pp. 18545-18552
-
-
Fujiwara, T.1
Oda, K.2
Yokota, S.3
Takatsuki, A.4
Ikehara, Y.5
-
29
-
-
0024591235
-
Rapid redistribution of Golgi proteins into the ER in cells treated with brefeldin A: Evidence for membrane cycling from Golgi to ER
-
DOI 10.1016/0092-8674(89)90685-5
-
Lippincott-Schwartz J, Yuan LC, Bonifacino JS, Klausner RD (1989) Rapid redistribution of Golgi proteins into the ER in cells treated with brefeldin A: evidence for membrane cycling from Golgi to ER. Cell 56:801-813 (Pubitemid 19082516)
-
(1989)
Cell
, vol.56
, Issue.5
, pp. 801-813
-
-
Lippincott-Schwartz, J.1
Yuan, L.C.2
Bonifacino, J.S.3
Klausner, R.D.4
-
30
-
-
0026776711
-
Post-Golgi membrane traffic: Brefeldin A inhibits export from distal Golgi compartments to the cell surface but not recycling
-
Miller SG, Carnell L, Moore HH (1992) Post-Golgi membrane traffic: brefeldin A inhibits export from distal Golgi compartments to the cell surface but not recycling. J Cell Biol 118:267-283
-
(1992)
J Cell Biol
, vol.118
, pp. 267-283
-
-
Miller, S.G.1
Carnell, L.2
Moore, H.H.3
-
31
-
-
0035827702
-
Retention of the Alzheimer's amyloid precursor fragment C99 in the endoplasmic reticulum prevents formation of amyloid beta-peptide
-
Maltese WA, Wilson S, Tan Y, Suomensaari S, Sinha S, Barbour R, McConlogue L (2001) Retention of the Alzheimer's amyloid precursor fragment C99 in the endoplasmic reticulum prevents formation of amyloid beta-peptide. J Biol Chem 276:20267-20279
-
(2001)
J Biol Chem
, vol.276
, pp. 20267-20279
-
-
Maltese, W.A.1
Wilson, S.2
Tan, Y.3
Suomensaari, S.4
Sinha, S.5
Barbour, R.6
McConlogue, L.7
-
32
-
-
0035921427
-
The discrepancy between presenilin subcellular localization and γ-secretase processing of amyloid precursor protein
-
DOI 10.1083/jcb.200104045
-
Cupers P, Bentahir M, Craessaerts K, Orlans I, Vanderstichele H, Saftig P, De Strooper B, Annaert W (2001) The discrepancy between presenilin subcellular localization and gamma-secretase processing of amyloid precursor protein. J Cell Biol 154:731-740 (Pubitemid 34292955)
-
(2001)
Journal of Cell Biology
, vol.154
, Issue.4
, pp. 731-740
-
-
Cupers, P.1
Bentahir, M.2
Craessaerts, K.3
Orlans, I.4
Vanderstichele, H.5
Saftig, P.6
De Strooper, B.7
Annaert, W.8
-
33
-
-
0027520440
-
Mis-assembly of clathrin lattices on endosomes reveals a regulatory switch for coated pit formation
-
DOI 10.1083/jcb.123.5.1107
-
Wang LH, Rothberg KG, Anderson RG (1993) Mis-assembly of clathrin lattices on endosomes reveals a regulatory switch for coated pit formation. J Cell Biol 123:1107-1117 (Pubitemid 23352421)
-
(1993)
Journal of Cell Biology
, vol.123
, Issue.5
, pp. 1107-1117
-
-
Wang, L.-H.1
Rothberg, K.G.2
Anderson, R.G.W.3
-
34
-
-
67650383731
-
Amyloid precursor protein and its homologues: A family ofproteolysis-dependent receptors
-
Jacobsen KT, Iverfeldt K (2009) Amyloid precursor protein and its homologues: a family ofproteolysis-dependent receptors. Cell Mol Life Sci 66:2299-2318
-
(2009)
Cell Mol Life Sci
, vol.66
, pp. 2299-2318
-
-
Jacobsen, K.T.1
Iverfeldt, K.2
-
35
-
-
2442498577
-
FE65 constitutes the functional link between the low-density lipoprotein receptor-related protein and the amyloid precursor protein
-
Pietrzik CU, Yoon IS, Jaeger S, Busse T, Weggen S, Koo EH (2004) FE65 constitutes the functional link between the low-density lipoprotein receptor-related protein and the amyloid precursor protein. J Neurosci 24:4259-4266
-
(2004)
J Neurosci
, vol.24
, pp. 4259-4266
-
-
Pietrzik, C.U.1
Yoon, I.S.2
Jaeger, S.3
Busse, T.4
Weggen, S.5
Koo, E.H.6
-
36
-
-
0035955693
-
The intracellular domain of the beta-amyloid precursor protein is stabilized by Fe65 and translocates to the nucleus in a notch-like manner
-
Kimberly WT, Zheng JB, Guénette SY, Selkoe DJ (2001) The intracellular domain of the beta-amyloid precursor protein is stabilized by Fe65 and translocates to the nucleus in a notch-like manner. J Biol Chem 276:40288-40292
-
(2001)
J Biol Chem
, vol.276
, pp. 40288-40292
-
-
Kimberly, W.T.1
Zheng, J.B.2
Guénette, S.Y.3
Selkoe, D.J.4
-
37
-
-
33646584550
-
The X11 proteins, Abeta production and Alzheimer's disease
-
Review
-
Miller CC, McLoughlin DM, Lau KF, Tennant ME, Rogelj B (2006) The X11 proteins, Abeta production and Alzheimer's disease. Trends Neurosci 5:280-285 Review
-
(2006)
Trends Neurosci
, vol.5
, pp. 280-285
-
-
Miller, C.C.1
McLoughlin, D.M.2
Lau, K.F.3
Tennant, M.E.4
Rogelj, B.5
-
38
-
-
0028213567
-
A heparin-binding domain in the amyloid protein precursor of Alzheimer's disease is involved in the regulation of neurite outgrowth
-
Small DH, Nurcombe V, Reed G, Clarris H, Moir R, Beyreuther K, Masters CL (1994) A heparin-binding domain in the amyloid protein precursor of Alzheimer's disease is involved in the reg-ulation of neurite outgrowth. J Neurosci 14:2117-2127 (Pubitemid 24108121)
-
(1994)
Journal of Neuroscience
, vol.14
, Issue.4
, pp. 2117-2127
-
-
Small, D.H.1
Nurcombe, V.2
Reed, G.3
Clarris, H.4
Moir, R.5
Beyreuther, K.6
Masters, C.L.7
-
39
-
-
0032945805
-
Crystal structure of the N-terminal, growth factor-like domain of Alzheimer amyloid precursor protein
-
Rossjohn J, Cappai R, Feil SC, Henry A, McKinstry WJ, Hesse L, Multhaup G, Beyreuther K, Masters CL, Parker MW (1999) Crystal structure of the N-terminal, growth factor-like domain of Alzheimer amyloid precursor protein. Nat Struct Biol 6:327-333
-
(1999)
Nat Struct Biol
, vol.6
, pp. 327-333
-
-
Rossjohn, J.1
Cappai, R.2
Feil, S.C.3
Henry, A.4
McKinstry, W.J.5
Hesse, L.6
Multhaup, G.7
Beyreuther, K.8
Masters, C.L.9
Parker, M.W.10
-
40
-
-
0032792982
-
A novel substrate for analyzing Alzheimer's disease γ-secretase
-
DOI 10.1016/S0014-5793(99)00730-9, PII S0014579399007309
-
Lichtenthaler SF, Multhaup G, Masters CL, Beyreuther K (1999) A novel substrate for analyzing Alzheimer's disease gamma-secretase. FEBS Lett 453:288-292 (Pubitemid 29326665)
-
(1999)
FEBS Letters
, vol.453
, Issue.3
, pp. 288-292
-
-
Lichtenthaler, S.F.1
Multhaup, G.2
Masters, C.L.3
Beyreuther, K.4
-
41
-
-
0024426526
-
The secreted form of the Alzheimer's amyloid precursor protein with the Kunitz domain is protease nexin-II
-
DOI 10.1038/341144a0
-
Oltersdorf T, Fritz LC, Schenk DB, Lieberburg I, Johnson-Wood KL, Beattie EC, Ward PJ, Blacher RW, Dovey HF, Sinha S (1989) The secreted form of the Alzheimer's amyloid precursor protein with the Kunitz domain is protease nexin-II. Nature 341:144-147 (Pubitemid 19222774)
-
(1989)
Nature
, vol.341
, Issue.6238
, pp. 144-147
-
-
Oltersdorf, T.1
Fritz, L.C.2
Schenk, D.B.3
Lieberburg, I.4
Johnson-Wood, K.L.5
Beattie, E.C.6
Ward, P.J.7
Blacher, R.W.8
Dovey, H.F.9
Sinha, S.10
-
42
-
-
0027959156
-
Protein disulphide isomerase: Building bridges in protein folding
-
DOI 10.1016/0968-0004(94)90072-8
-
Freedman RB, Hirst TR, Tuite MF (1994) Protein disulphide isomerase: building bridges in protein folding. Trends Biochem Sci 19:331-336 (Pubitemid 24259985)
-
(1994)
Trends in Biochemical Sciences
, vol.19
, Issue.8
, pp. 331-336
-
-
Freedman, R.B.1
Hirst, T.R.2
Tuite, M.F.3
-
43
-
-
0036836665
-
Proteins of the PDI family: Unpredicted non-ER locations and functions
-
Turano C, Coppari S, Altieri F, Ferraro A (2002) Proteins of the PDI family: unpredicted non-ER locations and functions. J Cell Physiol 193:154-163
-
(2002)
J Cell Physiol
, vol.193
, pp. 154-163
-
-
Turano, C.1
Coppari, S.2
Altieri, F.3
Ferraro, A.4
-
44
-
-
77953582321
-
What is the role of amyloid precursor protein dimerization?
-
Khalifa NB, Van Hees J, Tasiaux B, Huysseune S, Smith SO, Constantinescu SN, Octave JN, Kienlen-Campard P (2010) What is the role of amyloid precursor protein dimerization? Cell Adh Migr 4:268-272
-
(2010)
Cell Adh Migr
, vol.4
, pp. 268-272
-
-
Khalifa, N.B.1
Van Hees, J.2
Tasiaux, B.3
Huysseune, S.4
Smith, S.O.5
Constantinescu, S.N.6
Octave, J.N.7
Kienlen-Campard, P.8
-
47
-
-
70249091154
-
Trans-membrane structures of amyloid precursor protein dimer predicted by replica-exchange molecular dynamics simulations
-
Miyashita N, Straub JE, Thirumalai D, Sugita Y (2009) Trans-membrane structures of amyloid precursor protein dimer predicted by replica-exchange molecular dynamics simulations. J Am Chem Soc 131:3438-3439
-
(2009)
J Am Chem Soc
, vol.131
, pp. 3438-3439
-
-
Miyashita, N.1
Straub, J.E.2
Thirumalai, D.3
Sugita, Y.4
-
48
-
-
67649366042
-
Neuroprotective secreted amyloid precursor protein acts by disrupting amyloid precursor protein dimers
-
Gralle M, Botelho MG, Wouters FS (2009) Neuroprotective secreted amyloid precursor protein acts by disrupting amyloid precursor protein dimers. J Biol Chem 284:15016-15025
-
(2009)
J Biol Chem
, vol.284
, pp. 15016-15025
-
-
Gralle, M.1
Botelho, M.G.2
Wouters, F.S.3
-
49
-
-
34248172449
-
Structure and functions of the human amyloid precursor protein: The whole is more than the sum of its parts
-
DOI 10.1016/j.pneurobio.2007.02.001, PII S0301008207000160
-
Gralle M, Ferreira ST (2007) Structure and functions of the human amyloid precursor protein: the whole is more than the sum of its parts. Prog Neurobiol 82:11-32 (Pubitemid 46719589)
-
(2007)
Progress in Neurobiology
, vol.82
, Issue.1
, pp. 11-32
-
-
Gralle, M.1
Ferreira, S.T.2
-
50
-
-
33646439410
-
APP processing and the APP-KPI domain involvement in the amyloid cascade
-
Menendez Gonzalez M, Pérez-Pinera P, Martínez-Rivera M, Calatayud MT, Blázquez Menes B (2005) APP processing and the APP-KPI domain involvement in the amyloid cascade. Neu-rodegener Dis 2:277-283
-
(2005)
Neu-rodegener Dis
, vol.2
, pp. 277-283
-
-
Menendez Gonzalez, M.1
Pérez-Pinera, P.2
Martínez-Rivera, M.3
Calatayud, M.T.4
Blázquez Menes, B.5
-
51
-
-
0036836665
-
Proteins of the PDI family: Unpredicted non-ER locations and functions
-
Turano C, Coppari S, Altieri F, Ferraro A (2002) Proteins of the PDI family: Unpredicted non-ER locations and functions. J Cell Physiol 193:154-163
-
(2002)
J Cell Physiol
, vol.193
, pp. 154-163
-
-
Turano, C.1
Coppari, S.2
Altieri, F.3
Ferraro, A.4
-
52
-
-
0037145061
-
Ligand-induced, receptor-mediated dimerization and activation of EGF receptor
-
DOI 10.1016/S0092-8674(02)00966-2
-
Schlessinger J (2002) Ligand-induced, receptor-mediated dimer-ization and activation of EGF receptor. Cell 110:669-672 Review (Pubitemid 35283957)
-
(2002)
Cell
, vol.110
, Issue.6
, pp. 669-672
-
-
Schlessinger, J.1
-
53
-
-
0030030005
-
Regulation of amyloid protein precursor (APP) binding to collagen and mapping of the binding sites on APP and collagen type I
-
DOI 10.1074/jbc.271.3.1613
-
Beher D, Hesse L, Masters CL, Multhaup G (1996) Regulation of amyloid protein precursor (APP) binding to collagen and map-ping of the binding sites on APP and collagen type I. J Biol Chem 271:1613-1620 (Pubitemid 26028652)
-
(1996)
Journal of Biological Chemistry
, vol.271
, Issue.3
, pp. 1613-1620
-
-
Beher, D.1
Hesse, L.2
Masters, C.L.3
Multhaup, G.4
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