Association of Uric Acid With Inflammation, Progressive Renal Allograft Dysfunction and Post-Transplant Cardiovascular Risk

American Journal of Cardiology

Volumn 103, Issue 6, 2009, Pages 867-871

  Bandukwala, Farah ^a   Huang, Michael ^b   Zaltzman, Jeffrey S ^a,b   Nash, Michelle M ^b   Prasad, G V Ramesh ^a,b  

^a UNIVERSITY OF TORONTO   (Canada)

^b ST MICHAEL'S HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOPURINOL; ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT; ANGIOTENSIN RECEPTOR ANTAGONIST; ANTIGOUT AGENT; ANTIHYPERTENSIVE AGENT; ANTILIPEMIC AGENT; AZATHIOPRINE; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; C REACTIVE PROTEIN; CALCIUM CHANNEL BLOCKING AGENT; COLCHICINE; CYCLOSPORIN; DIHYDROPYRIDINE; DIURETIC AGENT; FIBRIC ACID DERIVATIVE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; IMMUNOSUPPRESSIVE AGENT; LOOP DIURETIC AGENT; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PREDNISONE; RAPAMYCIN; TACROLIMUS; THIAZIDE DIURETIC AGENT; TRIACYLGLYCEROL; URIC ACID;

ADULT; ARTICLE; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; DISEASE ASSOCIATION; FEMALE; GLOMERULUS FILTRATION RATE; GRAFT RECIPIENT; HUMAN; HYPERURICEMIA; INFLAMMATION; MAJOR CLINICAL STUDY; MALE; POSTOPERATIVE COMPLICATION; PRIORITY JOURNAL; RENAL GRAFT DYSFUNCTION;

ADULT; C-REACTIVE PROTEIN; CARDIOVASCULAR DISEASES; FEMALE; GLOMERULAR FILTRATION RATE; HUMANS; HYPERURICEMIA; INFLAMMATION; KIDNEY; KIDNEY DISEASES; KIDNEY TRANSPLANTATION; MALE; MIDDLE AGED; RISK FACTORS; TRANSPLANTATION, HOMOLOGOUS; URIC ACID;

EID: 61349127856     PISSN: 00029149     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.amjcard.2008.11.042     Document Type: Article

References (16)

1. Ducloux D., Kazory A., and Chaalopin J.M. Predicting coronary heart disease in renal transplant recipients: a prospective study. Kidney Int 66 (2004) 441-447
2. Winkelmayer W.C., Lorenz M., Kramar R., Fodinger M., Horl W.H., and Sunder-Plassmann G. C-reactive protein and body mass index independently predict mortality in kidney transplant recipients. Am J Transplant 4 (2004) 1148-1154
3. Teppo A.M., Tornroth T., Honkanen E., and Gronhagen-Riska C. Elevated serum C-reactive protein associates with deterioration of renal function in transplant recipients. Clin Nephrol 60 (2003) 248-256
4. Johnson R.J., Kang D.H., Feig D., Kivlighn S., Kanellis J., Watanabe S., Tuttle K.R., Rodriguez-Iturbe B., Herrera-Acosta J., and Mazzali M. Is there a pathogenetic role for uric acid in hypertension and cardiovascular and renal disease?. Hypertension 41 (2003) 1183-1190
5. Armstrong K.A., Johnson D.W., Campbell S.B., Isbel N.M., and Hawley C.M. Does uric acid have a pathogenetic role in graft dysfunction and hypertension in renal transplant recipients?. Transplantation 80 (2005) 1565-1571
6. Pearson T.A., Mensah G.A., Hong Y., and Smith Jr. S.C. CDC/AHA Workshop on Markers of Inflammation and Cardiovascular Disease: Application to Clinical and Public Health Practice: overview. Circulation 110 (2004) e543-e544
7. Akalin E., Ganeshan S.V., Winston J., and Muntner P. Hyperuricemia is associated with the development of the composite outcomes of new cardiovascular events and chronic allograft nephropathy. Transplantation 86 (2008) 652-658
8. Gerhardt U., Grobe H., and Hohage H. Influence of hyperglycemia and hyperuricemia on long-term transplant survival in kidney transplant patients. Clin Transplant 13 (1999) 375-379
9. Akgul A., Bilgic A., Ibis A., Ozdemir F.N., Arat Z., and Haberal M. Is uric acid a predictive factor for graft dysfunction in renal transplant recipients?. Transplant Proc 39 (2007) 1023-1026
10. Sundstrom J., Sullivan L., D'Agostino R.B., Levy D., Kannel W.B., and Vasan R.S. Relations of serum uric acid to longitudinal blood pressure tracking and hypertension incidence. Hypertension 45 (2005) 28-33
11. Feig D.I., and Johnson R.J. Hyperuricemia in childhood primary hypertension. Hypertension 42 (2003) 247-252
12. Brand F., McGee D., Kannel W., Stokes III J., and Castelli W. Hyperuricemia as a risk factor for coronary heart disease: the Framingham study. Am J Epidemiol 121 (1985) 11-18
13. Klein R., Klein B., Cornono J., Maready J., Cassel J., and Tyroler H. Serum uric acid. Its relationship to coronary heart disease risk factors and cardiovascular disease. Arch Int Med 132 (1973) 401-410
14. Fang J., and Alderman M. Serum uric acid and cardiovascular mortality: the NHANES I epidemiologic follow-up study, 1971-1972. JAMA 283 (2000) 2404-2410
15. Niskanen L., Laaksonen D., Nyssonenen K., Alfthan G., Lakka H.-M., Lakka T.A., and Salonen J.T. Uric acid level as a risk factor for cardiovascular and all-cause mortality in middle-aged men. Arch Intern Med 164 (2004) 1546-1551
16. Culleton B.F., Larson M.G., Kannel W.B., and Levy D. Serum uric acid and risk for cardiovascular disease and death: the Framingham Heart Study. Ann Intern Med 131 (1999) 7-13