-
1
-
-
0015914854
-
High association of an HLA antigen, W27, with ankylosing spondylitis
-
Schlosstein, L., Terasaki, P. I., Bluestone, R., Pearson, C. M. High association of an HLA antigen, W27, with ankylosing spondylitis. N. Engl. J. Med. 288, 704-706 (1973)
-
(1973)
N. Engl. J. Med.
, Issue.288
, pp. 704-706
-
-
Schlosstein, L.1
Terasaki, P.I.2
Bluestone, R.3
Pearson, C.M.4
-
2
-
-
0018887397
-
Histocompatibility alloantigens in psoriasis and psoriatic arthritis. Evidence for the influence of multiple genes in the major histocompatibility complex
-
Murray, C. et al. Histocompatibility alloantigens in psoriasis and psoriatic arthritis. Evidence for the influence of multiple genes in the major histocompatibility complex. J. Clin. Invest. 66, 670-675 (1980)
-
(1980)
J. Clin. Invest.
, vol.66
, pp. 670-675
-
-
Murray, C.1
-
3
-
-
0035978651
-
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
-
Hugot, J. P. et al. Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease. Nature 411, 599-603 (2001)
-
(2001)
Nature
, vol.411
, pp. 599-603
-
-
Hugot, J.P.1
-
4
-
-
0035978533
-
A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
-
Ogura, Y. et al. A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease. Nature 411, 603-606 (2001)
-
(2001)
Nature
, vol.411
, pp. 603-606
-
-
Ogura, Y.1
-
5
-
-
0030783099
-
Susceptibility to ankylosing spondylitis in twins: The role of genes HLA and the environment
-
Brown, M. A. et al. Susceptibility to ankylosing spondylitis in twins: The role of genes, HLA, and the environment. Arthritis Rheum. 40, 1823-1828 (1997)
-
(1997)
Arthritis Rheum.
, vol.40
, pp. 1823-1828
-
-
Brown, M.A.1
-
6
-
-
0033768546
-
Recurrence risk modeling of the genetic susceptibility to ankylosing spondylitis
-
Brown, M. A., Laval, S. H., Brophy, S. & Calin, A. Recurrence risk modeling of the genetic susceptibility to ankylosing spondylitis. Ann. Rheum. Dis. 59, 883-886 (2000)
-
(2000)
Ann. Rheum. Dis.
, vol.59
, pp. 883-886
-
-
Brown, M.A.1
Laval, S.H.2
Brophy, S.3
Calin, A.4
-
7
-
-
80054966401
-
Progress in the genetics of ankylosing spondylitis
-
Brown, M. A. Progress in the genetics of ankylosing spondylitis. Brief Funct. Genomics 10, 249-257 (2011)
-
(2011)
Brief Funct. Genomics
, vol.10
, pp. 249-257
-
-
Brown, M.A.1
-
8
-
-
0037189545
-
HLA B27 misfolding is associated with aberrant intermolecular disulfide bond formation (dimerization) in the endoplasmic reticulum
-
Dangoria, N. S. et al. HLA B27 misfolding is associated with aberrant intermolecular disulfide bond formation (dimerization) in the endoplasmic reticulum. J. Biol. Chem. 277, 23459-23468 (2002)
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 23459-23468
-
-
Dangoria, N.S.1
-
9
-
-
69449086287
-
HLA B27 misfolding and the unfolded protein response augment interleukin 23 production and are associated with TH17 activation in transgenic rats
-
Delay, M. L. et al. HLA B27 misfolding and the unfolded protein response augment interleukin 23 production and are associated with TH17 activation in transgenic rats. Arthritis Rheum. 60, 2633-2643 (2009)
-
(2009)
Arthritis Rheum.
, vol.60
, pp. 2633-2643
-
-
Delay, M.L.1
-
10
-
-
0036846149
-
Cell-surface expression and immune receptor recognition of HLA B27 homodimers
-
Kollnberger, S. et al. Cell-surface expression and immune receptor recognition of HLA B27 homodimers. Arthritis Rheum. 46, 2972-2982 (2002)
-
(2002)
Arthritis Rheum.
, vol.46
, pp. 2972-2982
-
-
Kollnberger, S.1
-
11
-
-
79957819259
-
Expression of MHC class I dimers and ERAP1 in an ankylosing spondylitis patient cohort
-
Campbell, E. C., Fettke, F., Bhat, S., Morley, K. D. & Powis, S. J. Expression of MHC class I dimers and ERAP1 in an ankylosing spondylitis patient cohort. Immunology 133, 379-385 (2011)
-
(2011)
Immunology
, vol.133
, pp. 379-385
-
-
Campbell, E.C.1
Fettke, F.2
Bhat, S.3
Morley, K.D.4
Powis, S.J.5
-
12
-
-
61549109883
-
The interplay between the geographic distribution of HLA B27 alleles and their role in infectious and autoimmune diseases: A unifying hypothesis
-
Mathieu, A. et al. The interplay between the geographic distribution of HLA B27 alleles and their role in infectious and autoimmune diseases: A unifying hypothesis. Autoimmun. Rev. 8, 420-425 (2009)
-
(2009)
Autoimmun. Rev.
, vol.8
, pp. 420-425
-
-
Mathieu, A.1
-
13
-
-
0142153570
-
Synovial Chlamydia trachomatis in patients with reactive arthritis/Reiter's syndrome are viable but show aberrant gene expression
-
Gerard, H. C., Branigan, P. J., Schumacher, H. R. & Hudson, A. P. Synovial Chlamydia trachomatis in patients with reactive arthritis/Reiter's syndrome are viable but show aberrant gene expression. J. Rheumatol. 25, 734-742 (1998)
-
(1998)
J. Rheumatol.
, vol.25
, pp. 734-742
-
-
Gerard, H.C.1
Branigan, P.J.2
Schumacher, H.R.3
Hudson, A.P.4
-
14
-
-
0021347628
-
The risk of developing ankylosing spondylitis in HLA B27 positive individuals. A comparison of relatives of spondylitis patients with the general population
-
van Der Linden, S. M., Valkenburg, H. A., De Jongh, B. M. & Cats, A. The risk of developing ankylosing spondylitis in HLA B27 positive individuals. A comparison of relatives of spondylitis patients with the general population. Arthritis Rheum. 27, 241-249 (1984)
-
(1984)
Arthritis Rheum.
, vol.27
, pp. 241-249
-
-
Van Der Linden, S.M.1
Valkenburg, H.A.2
De Jongh, B.M.3
Cats, A.4
-
15
-
-
0024462320
-
HLA-Bw60 increases susceptibility to ankylosing spondylitis in HLA B27+ patients
-
Robinson, W. P. et al. HLA-Bw60 increases susceptibility to ankylosing spondylitis in HLA B27+ patients. Arthritis Rheum. 32, 1135-1141 (1989)
-
(1989)
Arthritis Rheum.
, vol.32
, pp. 1135-1141
-
-
Robinson, W.P.1
-
16
-
-
0029879899
-
HLA class I associations of ankylosing spondylitis in the white population in the United Kingdom
-
Brown, M. A. et al. HLA class I associations of ankylosing spondylitis in the white population in the United Kingdom. Ann. Rheum. Dis. 55, 268-270 (1996)
-
(1996)
Ann. Rheum. Dis.
, vol.55
, pp. 268-270
-
-
Brown, M.A.1
-
17
-
-
3242890497
-
HLA B60 and B61 are strongly associated with ankylosing spondylitis in HLA B27 negative Taiwan Chinese patients
-
Wei, J. C., Tsai, W. C., Lin, H. S., Tsai, C. Y. & Chou, C. T. HLA B60 and B61 are strongly associated with ankylosing spondylitis in HLA B27 negative Taiwan Chinese patients Rheumatology (Oxford) 43, 839-842 (2004)
-
(2004)
Rheumatology (Oxford)
, Issue.43
, pp. 839-842
-
-
Wei, J.C.1
Tsai, W.C.2
Lin, H.S.3
Tsai, C.Y.4
Chou, C.T.5
-
18
-
-
79953004299
-
The genetic basis of spondyloarthritis
-
Reveille, J. D. The genetic basis of spondyloarthritis. Ann. Rheum. Dis. 70 (Suppl. 1), i44-i50 (2011)
-
(2011)
Ann. Rheum. Dis.
, vol.70
, Issue.SUPPL. 1
-
-
Reveille, J.D.1
-
19
-
-
79960899377
-
Interaction between ERAP1 and HLA B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA B27 in disease susceptibility
-
Evans, D. M. et al. Interaction between ERAP1 and HLA B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA B27 in disease susceptibility. Nat. Genet. 43, 761-767 (2011)
-
(2011)
Nat. Genet.
, vol.43
, pp. 761-767
-
-
Evans, D.M.1
-
20
-
-
35748981184
-
Association scan of 14,500 nsSNPs in four common diseases identifies variants involved in autoimmunity
-
Wellcome Trust Case Control Consortium et al.
-
Wellcome Trust Case Control Consortium et al. Association scan of 14,500 nsSNPs in four common diseases identifies variants involved in autoimmunity. Nat. Genet. 39, 1329-1337 (2007)
-
(2007)
Nat. Genet.
, vol.39
, pp. 1329-1337
-
-
-
21
-
-
75749085686
-
Genomewide association study of ankylosing spondylitis identifies multiple non-MHC susceptibility loci
-
Australo Anglo American Spondyloarthritis Consortium
-
Australo Anglo American Spondyloarthritis Consortium et al. Genomewide association study of ankylosing spondylitis identifies multiple non-MHC susceptibility loci. Nat. Genet. 42, 123-127 (2010)
-
(2010)
Nat. Genet.
, vol.42
, pp. 123-127
-
-
-
22
-
-
66049103503
-
Association of a specific ERAP1/ARTS1 haplotype with disease susceptibility in ankylosing spondylitis
-
Maksymowych, W. P. et al. Association of a specific ERAP1/ARTS1 haplotype with disease susceptibility in ankylosing spondylitis. Arthritis Rheum. 60, 1317-1323 (2009)
-
(2009)
Arthritis Rheum.
, vol.60
, pp. 1317-1323
-
-
Maksymowych, W.P.1
-
23
-
-
77950331522
-
Association of an ERAP1/ ERAP2 haplotype with familial ankylosing spondylitis
-
Tsui, F. W. et al. Association of an ERAP1/ ERAP2 haplotype with familial ankylosing spondylitis. Ann. Rheum. Dis. 69, 733-736 (2010)
-
(2010)
Ann. Rheum. Dis.
, vol.69
, pp. 733-736
-
-
Tsui, F.W.1
-
24
-
-
72949094188
-
Association of IL23R and ERAP1 genes with ankylosing spondylitis in a Portuguese population
-
Pimentel-Santos, F. M. et al. Association of IL23R and ERAP1 genes with ankylosing spondylitis in a Portuguese population. Clin. Exp. Rheumatol. 27, 800-806 (2009)
-
(2009)
Clin. Exp. Rheumatol.
, vol.27
, pp. 800-806
-
-
Pimentel-Santos, F.M.1
-
25
-
-
76649083225
-
Association of ARTS1 gene polymorphisms with ankylosing spondylitis in the Hungarian population: The rs27044 variant is associated with HLA B*2705 subtype in Hungarian patients with ankylosing spondylitis
-
Paźr, B. et al. Association of ARTS1 gene polymorphisms with ankylosing spondylitis in the Hungarian population: The rs27044 variant is associated with HLA B. *2705 subtype in Hungarian patients with ankylosing spondylitis. J. Rheumatol. 37, 379-384 (2010)
-
(2010)
J. Rheumatol.
, vol.37
, pp. 379-384
-
-
Paźr, B.1
-
26
-
-
70350525335
-
Association of ERAP1, but not IL23R, with ankylosing spondylitis in a Han Chinese population
-
Davidson, S. I. et al. Association of ERAP1, but not IL23R, with ankylosing spondylitis in a Han Chinese population. Arthritis Rheum. 60, 3263-3268 (2009)
-
(2009)
Arthritis Rheum.
, vol.60
, pp. 3263-3268
-
-
Davidson, S.I.1
-
27
-
-
79551717945
-
Genetic studies of ankylosing spondylitis in Koreans confirm associations with ERAP1 and 2p15 reported in white patients
-
Bang, S. Y. et al. Genetic studies of ankylosing spondylitis in Koreans confirm associations with ERAP1 and 2p15 reported in white patients. J. Rheumatol. 38, 322-324 (2011)
-
(2011)
J. Rheumatol.
, vol.38
, pp. 322-324
-
-
Bang, S.Y.1
-
28
-
-
33645089946
-
In vivo role of ER associated peptidase activity in tailoring peptides for presentation by MHC class Ia and class Ib molecules
-
Yan, J. et al. In vivo role of ER associated peptidase activity in tailoring peptides for presentation by MHC class Ia and class Ib molecules. J. Exp. Med. 203, 647-659 (2006)
-
(2006)
J. Exp. Med.
, vol.203
, pp. 647-659
-
-
Yan, J.1
-
29
-
-
78049347495
-
A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA C and ERAP1
-
Genetic Analysis of Psoriasis Consortium and the Wellcome Trust Case Control Consortium 2
-
Genetic Analysis of Psoriasis Consortium and the Wellcome Trust Case Control Consortium 2. A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA C and ERAP1. Nat. Genet. 42, 985-990 (2010)
-
(2010)
Nat. Genet.
, vol.42
, pp. 985-990
-
-
-
30
-
-
79956348710
-
Crystal structures of the endoplasmic reticulum aminopeptidase 1 (ERAP1) reveal the molecular basis for N terminal peptide trimming
-
Kochan, G. et al. Crystal structures of the endoplasmic reticulum aminopeptidase 1 (ERAP1) reveal the molecular basis for N terminal peptide trimming. Proc. Natl Acad. Sci. USA 108, 7745-7750 (2011)
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 7745-7750
-
-
Kochan, G.1
-
31
-
-
0036679366
-
Identification of ARTS 1 as a novel TNFR1-binding protein that promotes TNFR1 ectodomain shedding
-
Cui, X. et al. Identification of ARTS 1 as a novel TNFR1-binding protein that promotes TNFR1 ectodomain shedding. J. Clin. Invest. 110, 515-526 (2002)
-
(2002)
J. Clin. Invest.
, vol.110
, pp. 515-526
-
-
Cui, X.1
-
32
-
-
77956470985
-
Serum cytokine receptors in ankylosing spondylitis: Relationship to inflammatory markers and endoplasmic reticulum aminopeptidase polymorphisms
-
Haroon, N., Tsui, F. W., Chiu, B., Tsui, H. W. & Inman, R. D. Serum cytokine receptors in ankylosing spondylitis: Relationship to inflammatory markers and endoplasmic reticulum aminopeptidase polymorphisms. J. Rheumatol. 37, 1907-1910 (2010)
-
(2010)
J. Rheumatol.
, Issue.37
, pp. 1907-1910
-
-
Haroon, N.1
Tsui, F.W.2
Chiu, B.3
Tsui, H.W.4
Inman, R.D.5
-
33
-
-
33845340501
-
A genome-wide association study identifies IL23R as an inflammatory bowel disease gene
-
Duerr, R. H. et al. A genome-wide association study identifies IL23R as an inflammatory bowel disease gene. Science 314, 1461-1463 (2006)
-
(2006)
Science
, vol.314
, pp. 1461-1463
-
-
Duerr, R.H.1
-
34
-
-
33846608131
-
A large-scale genetic association study confirms IL12B and leads to the identification of IL23R as psoriasis-risk genes
-
Cargill, M. et al. A large-scale genetic association study confirms IL12B and leads to the identification of IL23R as psoriasis-risk genes. Am. J. Hum. Genet. 80, 273-290 (2007)
-
(2007)
Am. J. Hum. Genet.
, vol.80
, pp. 273-290
-
-
Cargill, M.1
-
35
-
-
63249118198
-
Association between the interleukin 23 receptor and ankylosing spondylitis is confirmed by a new UK case-control study and meta-Analysis of published series
-
Karaderi, T. et al. Association between the interleukin 23 receptor and ankylosing spondylitis is confirmed by a new UK case-control study and meta-Analysis of published series. Rheumatology (Oxford) 48, 386-389 (2009)
-
(2009)
Rheumatology (Oxford)
, vol.48
, pp. 386-389
-
-
Karaderi, T.1
-
36
-
-
42449146934
-
Association of interleukin 23 receptor variants with ankylosing spondylitis
-
Rahman, P. et al. Association of interleukin 23 receptor variants with ankylosing spondylitis. Arthritis Rheum. 58, 1020-1025 (2008)
-
(2008)
Arthritis Rheum.
, vol.58
, pp. 1020-1025
-
-
Rahman, P.1
-
37
-
-
53049097091
-
The IL23R Arg381Gln non-synonymous polymorphism confers susceptibility to ankylosing spondylitis
-
Rueda, B. et al. The IL23R Arg381Gln non-synonymous polymorphism confers susceptibility to ankylosing spondylitis. Ann. Rheum. Dis. 67, 1451-1454 (2008)
-
(2008)
Ann. Rheum. Dis.
, vol.67
, pp. 1451-1454
-
-
Rueda, B.1
-
38
-
-
77749340379
-
Interleukin 23 receptor gene variants in Hungarian systemic lupus erythematosus patients
-
Safrany, E. et al. Interleukin 23 receptor gene variants in Hungarian systemic lupus erythematosus patients. Inflamm. Res. 59, 159-164 (2010)
-
(2010)
Inflamm. Res.
, vol.59
, pp. 159-164
-
-
Safrany, E.1
-
39
-
-
67449105675
-
IL 23R polymorphisms in patients with ankylosing spondylitis in Korea
-
Sung, I. H. et al. IL 23R polymorphisms in patients with ankylosing spondylitis in Korea. J. Rheum. 236, 1003-1005 (2009)
-
(2009)
J. Rheum.
, vol.236
, pp. 1003-1005
-
-
Sung, I.H.1
-
40
-
-
78751706438
-
Association of STAT3 and TNFSF1A with ankylosing spondylitis in Han Chinese
-
Davidson, S. I. et al.Association of STAT3 and TNFSF1A with ankylosing spondylitis in Han Chinese. Ann. Rheum. Dis. 70, 289-292 (2011)
-
(2011)
Ann. Rheum. Dis.
, vol.70
, pp. 289-292
-
-
Davidson, S.I.1
-
41
-
-
52949091918
-
Loci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel disease
-
Kugathasan, S. et al. Loci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel disease. Nat. Genet. 40, 1211-1215 (2008)
-
(2008)
Nat. Genet.
, vol.40
, pp. 1211-1215
-
-
Kugathasan, S.1
-
42
-
-
0035684706
-
A polymorphism within the interleukin 1 receptor antagonist (IL-1Ra) gene is associated with ankylosing spondylitis
-
McGarry, F., Neilly, J., Anderson, N., Sturrock, R. & Field, M. A polymorphism within the interleukin 1 receptor antagonist (IL-1Ra) gene is associated with ankylosing spondylitis. Rheumatology (Oxford) 40, 1359-1364 (2001)
-
(2001)
Rheumatology (Oxford)
, Issue.40
, pp. 1359-1364
-
-
McGarry, F.1
Neilly, J.2
Anderson, N.3
Sturrock, R.4
Field, M.5
-
43
-
-
0036886367
-
Interleukin-1β and interleukin 1 receptor antagonist gene polymorphisms in ankylosing spondylitis
-
van Der Paardt, M. et al. Interleukin-1β and interleukin 1 receptor antagonist gene polymorphisms in ankylosing spondylitis. Rheumatology (Oxford) 41, 1419-1423 (2002)
-
(2002)
Rheumatology (Oxford)
, vol.41
, pp. 1419-1423
-
-
Van Der Paardt, M.1
-
44
-
-
0038342695
-
High-throughput single-nucleotide polymorphism analysis of the IL1RN locus in patients with ankylosing spondylitis by matrix-Assisted laser desorption ionization time of-flight mass spectrometry
-
Maksymowych, W. P. et al. High-throughput single-nucleotide polymorphism analysis of the IL1RN locus in patients with ankylosing spondylitis by matrix-Assisted laser desorption ionization time of-flight mass spectrometry. Arthritis Rheum. 48, 2011-2018 (2003)
-
(2003)
Arthritis Rheum.
, vol.48
, pp. 2011-2018
-
-
Maksymowych, W.P.1
-
45
-
-
33746541039
-
Replication of association of IL 1 gene complex members with ankylosing spondylitis in Taiwanese Chinese
-
Chou, C. T. et al. Replication of association of IL 1 gene complex members with ankylosing spondylitis in Taiwanese Chinese. Ann. Rheum. Dis. 65, 1106-1109 (2006)
-
(2006)
Ann. Rheum. Dis.
, vol.65
, pp. 1106-1109
-
-
Chou, C.T.1
-
46
-
-
4544361392
-
The interleukin 1 gene cluster contains a major susceptibility locus for ankylosing spondylitis
-
Timms, A. E. et al. The interleukin 1 gene cluster contains a major susceptibility locus for ankylosing spondylitis. Am. J. Hum. Genet. 75, 587-595 (2004)
-
(2004)
Am. J. Hum. Genet.
, vol.75
, pp. 587-595
-
-
Timms, A.E.1
-
47
-
-
50249179211
-
Prospective meta-Analysis of interleukin 1 gene complex polymorphisms confirms associations with ankylosing spondylitis
-
Sims, A. M. et al. Prospective meta-Analysis of interleukin 1 gene complex polymorphisms confirms associations with ankylosing spondylitis. Ann. Rheum. Dis. 67, 1305-1309 (2008)
-
(2008)
Ann. Rheum. Dis.
, vol.67
, pp. 1305-1309
-
-
Sims, A.M.1
-
48
-
-
13244279795
-
Open label trial of anakinra in active ankylosing spondylitis over 24 weeks
-
Haibel, H., Rudwaleit, M., Listing, J. & Sieper, J. Open label trial of anakinra in active ankylosing spondylitis over 24 weeks. Ann. Rheum. Dis. 64, 296-298 (2005)
-
(2005)
Ann. Rheum. Dis.
, vol.64
, pp. 296-298
-
-
Haibel, H.1
Rudwaleit, M.2
Listing, J.3
Sieper, J.4
-
49
-
-
0142122899
-
Mutations in capillary morphogenesis gene 2 result in the allelic disorders juvenile hyaline fibromatosis and infantile systemic hyalinosis
-
Dowling, O. et al. Mutations in capillary morphogenesis gene 2 result in the allelic disorders juvenile hyaline fibromatosis and infantile systemic hyalinosis. Am. J. Hum. Genet. 73, 957-966 (2003)
-
(2003)
Am. J. Hum. Genet.
, vol.73
, pp. 957-966
-
-
Dowling, O.1
-
50
-
-
76949084912
-
Signaling by intrathymic cytokines, not T cell antigen receptors, specifies CD8 lineage choice and promotes the differentiation of cytotoxic-lineage T cells
-
Park, J. H. et al. Signaling by intrathymic cytokines, not T cell antigen receptors, specifies CD8 lineage choice and promotes the differentiation of cytotoxic-lineage T cells. Nat. Immunol. 11, 257-264 (2010)
-
(2010)
Nat. Immunol.
, vol.11
, pp. 257-264
-
-
Park, J.H.1
-
51
-
-
60249084148
-
Ustekinumab, a human interleukin 12/23 monoclonal antibody, for psoriatic arthritis: Randomised, double-blind, placebo-controlled, crossover trial
-
Gottlieb, A. et al. Ustekinumab, a human interleukin 12/23 monoclonal antibody, for psoriatic arthritis: Randomised, double-blind, placebo-controlled, crossover trial. Lancet 373, 633-640 (2009)
-
(2009)
Lancet
, vol.373
, pp. 633-640
-
-
Gottlieb, A.1
-
52
-
-
78650711124
-
Association of variants at 1q32 and STAT3 with ankylosing spondylitis suggests genetic overlap with Crohn's disease
-
Danoy, P. et al. Association of variants at 1q32 and STAT3 with ankylosing spondylitis suggests genetic overlap with Crohn's disease. PLoS Genet. 6, e1001195 (2010)
-
(2010)
PLoS Genet.
, vol.6
-
-
Danoy, P.1
-
53
-
-
39549089300
-
Mesenchymal cell targeting by TNF as a common pathogenic principle in chronic inflammatory joint and intestinal diseases
-
Armaka, M. et al. Mesenchymal cell targeting by TNF as a common pathogenic principle in chronic inflammatory joint and intestinal diseases. J. Exp. Med. 205, 331-337 (2008)
-
(2008)
J. Exp. Med.
, vol.205
, pp. 331-337
-
-
Armaka, M.1
-
54
-
-
12144289400
-
A physical and functional map of the human TNF-A/NF ? B signal transduction pathway
-
Bouwmeester, T. et al. A physical and functional map of the human TNF-A/NF ? B signal transduction pathway. Nat. Cell Biol. 6, 97-105 (2004)
-
(2004)
Nat. Cell Biol.
, vol.6
, pp. 97-105
-
-
Bouwmeester, T.1
-
55
-
-
77953702946
-
The chromosome 16q region associated with ankylosing spondylitis includes the candidate gene tumour necrosis factor receptor type 1-Associated death domain (TRADD)
-
Pointon, J. J. et al.The chromosome 16q region associated with ankylosing spondylitis includes the candidate gene tumour necrosis factor receptor type 1-Associated death domain (TRADD). Ann. Rheum. Dis. 69, 1243-1246 (2010)
-
(2010)
Ann. Rheum. Dis.
, vol.69
, pp. 1243-1246
-
-
Pointon, J.J.1
-
56
-
-
77956344915
-
Elucidating the chromosome 9 association with AS; CARD9 is a candidate gene
-
Pointon, J. J. et al. Elucidating the chromosome 9 association with AS; CARD9 is a candidate gene. Genes Immun. 11, 490-496 (2010)
-
(2010)
Genes Immun.
, vol.11
, pp. 490-496
-
-
Pointon, J.J.1
-
57
-
-
56549104117
-
CARD9 signaling in the innate immune response
-
Ruland, J. CARD9 signaling in the innate immune response. Ann. NY Acad. Sci. 1143, 35-44 (2008)
-
(2008)
Ann. N. Y. Acad. Sci.
, vol.1143
, pp. 35-44
-
-
Ruland, J.1
-
58
-
-
34249026701
-
Syk-And CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17
-
LeibundGut-Landmann, S. et al. Syk-And CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17. Nat. Immunol. 8, 630-638 (2007)
-
(2007)
Nat. Immunol.
, vol.8
, pp. 630-638
-
-
LeibundGut-Landmann, S.1
-
59
-
-
78649575937
-
Endogenous PGE2 promotes the induction of human TH17 responses by fungal β glucan
-
Gagliardi, M. C. et al. Endogenous PGE2 promotes the induction of human TH17 responses by fungal β glucan. J. Leukoc. Biol. 88, 947-954 (2010)
-
(2010)
J. Leukoc. Biol.
, vol.88
, pp. 947-954
-
-
Gagliardi, M.C.1
-
60
-
-
0025646974
-
Follow-up study of ankylosing spondylitis over a period of 12 years 1977-1989)
-
Dekker-Saeys, AJ, Keat, A. Follow-up study of ankylosing spondylitis over a period of 12 years (1977-1989). Scand. J. Rheumatol. 87 (Suppl.), 120-121(1990)
-
(1990)
Scand. J. Rheumatol.
, vol.87
, pp. 120-121
-
-
Dekker-Saeys, A.J.1
Keat, A.2
-
61
-
-
0036181642
-
HLA Cw6 positive and HLA Cw6 negative patients with psoriasis vulgaris have distinct clinical features
-
Gudjónsson J, E, et al. HLA Cw6 positive and HLA Cw6 negative patients with psoriasis vulgaris have distinct clinical features. J. Invest. Dermatol. 118, 362-365 (2002)
-
(2002)
J. Invest. Dermatol.
, vol.118
, pp. 362-365
-
-
Gudjónsson, J.E.1
-
62
-
-
0033927713
-
Localization of psoriasis-susceptibility locus PSORS1 to a 60 kb interval telomeric to HLA C
-
Nair, R. P. et al. Localization of psoriasis-susceptibility locus PSORS1 to a 60 kb interval telomeric to HLA C. Am. J. Hum. Genet. 66, 1833-1844 (2000)
-
(2000)
Am. J. Hum. Genet.
, vol.66
, pp. 1833-1844
-
-
Nair, R.P.1
-
63
-
-
33646049742
-
Sequence and haplotype analysis supports HLA C as the psoriasis susceptibility 1 gene
-
Nair, R. P. et al. Sequence and haplotype analysis supports HLA C as the psoriasis susceptibility 1 gene. Am. J. Hum. Genet. 78, 827-851 (2006)
-
(2006)
Am. J. Hum. Genet.
, vol.78
, pp. 827-851
-
-
Nair, R.P.1
-
64
-
-
70149090668
-
Multiple loci within the major histocompatibility complex confer risk of psoriasis
-
Feng, B. J. et al. Multiple loci within the major histocompatibility complex confer risk of psoriasis. PLoS Genet. 5, e1000606 (2009)
-
(2009)
PLoS Genet.
, vol.5
-
-
Feng, B.J.1
-
65
-
-
0033618504
-
Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA
-
Bauer, S. et al. Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA. Science 285, 727-729 (1999)
-
(1999)
Science
, vol.285
, pp. 727-729
-
-
Bauer, S.1
-
66
-
-
33845783691
-
Increased expression of Wnt5a in psoriatic plaques
-
Reischl, J. et al. Increased expression of Wnt5a in psoriatic plaques. J. Invest. Dermatol. 127, 163-169 (2007)
-
(2007)
J. Invest. Dermatol.
, vol.127
, pp. 163-169
-
-
Reischl, J.1
-
67
-
-
67349236684
-
Genome-wide association scan yields new insights into the immuno-pathogenesis of psoriasis
-
Elder, J. T. Genome-wide association scan yields new insights into the immuno-pathogenesis of psoriasis. Genes Immun. 10, 201-209 (2009)
-
(2009)
Genes Immun.
, vol.10
, pp. 201-209
-
-
Elder, J.T.1
-
68
-
-
42149140747
-
Polymorphisms of the IL12B and IL23R genes are associated with psoriasis
-
Nair RP. et al. Polymorphisms of the IL12B and IL23R genes are associated with psoriasis. J. Invest. Dermatol. 128, 1653-1661 (2008).
-
(2008)
J. Invest. Dermatol.
, vol.128
, pp. 1653-1661
-
-
Nair, R.P.1
-
69
-
-
40449098551
-
ADAM33, a new candidate for psoriasis susceptibility
-
Lesueur, F. et al. ADAM33, a new candidate for psoriasis susceptibility. PLoS ONE 2, e906 (2007)
-
(2007)
Plos One
, vol.2
-
-
Lesueur, F.1
-
70
-
-
43249083380
-
A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci
-
Liu, Y. et al. A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci. PLoS Genet. 4, e1000041 (2008)
-
(2008)
Plos Genet.
, vol.4
-
-
Liu, Y.1
-
71
-
-
59149106117
-
Genome-wide scan reveals association of psoriasis with IL 23 and NF ?B pathways
-
Nair, R. P. et al. Genome-wide scan reveals association of psoriasis with IL 23 and NF ?B pathways. Nat. Genet. 41, 199-204(2009)
-
(2009)
Nat. Genet.
, vol.41
, pp. 199-204
-
-
Nair, R.P.1
-
72
-
-
78049323656
-
Genome-wide association analysis identifies three psoriasis susceptibility loci
-
Stuart, P. E. et al. Genome-wide association analysis identifies three psoriasis susceptibility loci. Nat. Genet. 42, 1000-1004 (2010)
-
(2010)
Nat. Genet.
, vol.42
, pp. 1000-1004
-
-
Stuart, P.E.1
-
73
-
-
59949092668
-
Further genetic evidence for three psoriasis-risk genes: ADAM33 CDKAL1 and PTPN22
-
Li, Y. et al. Further genetic evidence for three psoriasis-risk genes: ADAM33, CDKAL1, and PTPN22. J. Invest Dermatol. 129, 629-634 (2009)
-
(2009)
J. Invest Dermatol.
, vol.129
, pp. 629-634
-
-
Li, Y.1
-
74
-
-
78049329814
-
Association analyses identify six new psoriasis susceptibility loci in the Chinese population
-
Sun, L. D. et al. Association analyses identify six new psoriasis susceptibility loci in the Chinese population. Nat. Genet. 42, 1005-1009 (2010)
-
(2010)
Nat. Genet.
, vol.42
, pp. 1005-1009
-
-
Sun, L.D.1
-
75
-
-
78049343768
-
Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2
-
Ellinghaus, E. et al. Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2. Nat. Genet. 242, 991-995 (2010)
-
(2010)
Nat. Genet.
, vol.242
, pp. 991-995
-
-
Ellinghaus, E.1
-
76
-
-
78049350350
-
Common variants at TRAF3IP2 are associated with susceptibility to psoriatic arthritis and psoriasis
-
Hüffmeier, U. et al. Common variants at TRAF3IP2 are associated with susceptibility to psoriatic arthritis and psoriasis. Nat. Genet. 42, 996-999 (2010)
-
(2010)
Nat. Genet.
, vol.42
, pp. 996-999
-
-
Hüffmeier, U.1
-
77
-
-
34247873196
-
The adaptor Act1 is required for interleukin 17-dependent signaling associated with autoimmune and inflammatory disease
-
Qian, Y. et al. The adaptor Act1 is required for interleukin 17-dependent signaling associated with autoimmune and inflammatory disease. Nat. Immunol. 8, 247-256 (2007)
-
(2007)
Nat. Immunol.
, vol.8
, pp. 247-256
-
-
Qian, Y.1
-
78
-
-
59149096149
-
Psoriasis genome-wide association study identifies susceptibility variants within LCE gene cluster at 1q21
-
Zhang, X. J. et al. Psoriasis genome-wide association study identifies susceptibility variants within LCE gene cluster at 1q21. Nat. Genet. 41, 205-210 (2009)
-
(2009)
Nat. Genet.
, vol.41
, pp. 205-210
-
-
Zhang, X.J.1
-
79
-
-
59149098800
-
Deletion of the late cornified envelope LCE3B and LCE3C genes as a susceptibility factor for psoriasis
-
De Cid, R. et al. Deletion of the late cornified envelope LCE3B and LCE3C genes as a susceptibility factor for psoriasis. Nat. Genet. 41, 211-215 (2009)
-
(2009)
Nat. Genet.
, vol.41
, pp. 211-215
-
-
De Cid, R.1
-
80
-
-
79956131426
-
Differential major histocompatibility complex class I chain-related A allele associations with skin and joint manifestations of psoriatic disease
-
Pollock, R. et al. Differential major histocompatibility complex class I chain-related A allele associations with skin and joint manifestations of psoriatic disease. Tissue Antigens 77, 554-561(2011)
-
(2011)
Tissue Antigens
, vol.77
, pp. 554-561
-
-
Pollock, R.1
-
81
-
-
79952363588
-
High resolution mapping in the major histocompatibility complex region identifies multiple independent novel loci for psoriatic arthritis
-
Rahman, P. et al. High resolution mapping in the major histocompatibility complex region identifies multiple independent novel loci for psoriatic arthritis. Ann. Rheum. Dis. 70, 690-694 (2011)
-
(2011)
Ann. Rheum. Dis.
, vol.70
, pp. 690-694
-
-
Rahman, P.1
-
82
-
-
33745926540
-
Association between the interleukin 1 family gene cluster and psoriatic arthritis
-
Rahman, P. et al. Association between the interleukin 1 family gene cluster and psoriatic arthritis. Arthritis Rheum. 54, 2321-2325 (2006)
-
(2006)
Arthritis Rheum.
, vol.54
, pp. 2321-2325
-
-
Rahman, P.1
-
83
-
-
0347724078
-
Interleukin 1a, interleukin 1β and interleukin 1 receptor gene polymorphisms in psoriatic arthritis
-
Ravindran, J. S. et al. Interleukin 1a, interleukin 1β and interleukin 1 receptor gene polymorphisms in psoriatic arthritis. Rheumatology (Oxford) 43, 22-26 (2004)
-
(2004)
Rheumatology (Oxford)
, vol.43
, pp. 22-26
-
-
Ravindran, J.S.1
-
84
-
-
80051474642
-
Confirmation of TNIP1 and IL23A as susceptibility loci for psoriatic arthritis
-
Bowes, J. et al. Confirmation of TNIP1 and IL23A as susceptibility loci for psoriatic arthritis. Ann. Rheum. Dis. 70, 1641-1644 (2011)
-
(2011)
Ann. Rheum. Dis.
, vol.70
, pp. 1641-1644
-
-
Bowes, J.1
-
85
-
-
79958169705
-
Association between IL13 polymorphisms and psoriatic arthritis is modified by smoking
-
Duffin, K. C. et al. Association between IL13 polymorphisms and psoriatic arthritis is modified by smoking. J. Invest. Dermatol. 129, 2777-2783 (2009)
-
(2009)
J. Invest. Dermatol.
, vol.129
, pp. 2777-2783
-
-
Duffin, K.C.1
-
86
-
-
79955846991
-
Evidence to support IL 13 as a risk locus for psoriatic arthritis but not psoriasis vulgaris
-
Bowes, J. et al. Evidence to support IL 13 as a risk locus for psoriatic arthritis but not psoriasis vulgaris. Ann. Rheum. Dis. 70, 1016-1019 (2011)
-
(2011)
Ann. Rheum. Dis.
, vol.70
, pp. 1016-1019
-
-
Bowes, J.1
-
87
-
-
78649750839
-
Variants in linkage disequilibrium with the late cornified envelope gene cluster deletion are associated with susceptibility to psoriatic arthritis
-
Bowes, J. et al. Variants in linkage disequilibrium with the late cornified envelope gene cluster deletion are associated with susceptibility to psoriatic arthritis. Ann. Rheum. Dis. 69, 2199-2203 (2010)
-
(2010)
Ann. Rheum. Dis.
, vol.69
, pp. 2199-2203
-
-
Bowes, J.1
-
88
-
-
77951542374
-
Deletion of LCE3C and LCE3B genes at PSORS4 does not contribute to susceptibility to psoriatic arthritis in German patients
-
Huffmeier, U. et al. Deletion of LCE3C and LCE3B genes at PSORS4 does not contribute to susceptibility to psoriatic arthritis in German patients. Ann. Rheum. Dis. 69, 876-878 (2010)
-
(2010)
Ann. Rheum. Dis.
, vol.69
, pp. 876-878
-
-
Huffmeier, U.1
-
89
-
-
0026327181
-
Gut inflammation in the spondyloarthropathies: Clinical, radiologic, biologic and genetic features in relation to the type of histology. A prospective study
-
Mielants, H. et al. Gut inflammation in the spondyloarthropathies: Clinical, radiologic, biologic and genetic features in relation to the type of histology. A prospective study. J. Rheumatol. 18, 1542-1551 (1991)
-
(1991)
J. Rheumatol.
, vol.18
, pp. 1542-1551
-
-
Mielants, H.1
-
90
-
-
73849151394
-
A NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation
-
Cooney, R. et al. A. NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation. Nat. Med. 16, 90-97, (2010)
-
(2010)
Nat. Med.
, vol.16
, pp. 90-97
-
-
Cooney, R.1
-
91
-
-
34247554965
-
Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis
-
Rioux, J. D. et al. Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis. Nat. Genet. 39, 596-604 (2007)
-
(2007)
Nat. Genet.
, vol.39
, pp. 596-604
-
-
Rioux, J.D.1
-
92
-
-
33846627302
-
A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1
-
Hampe, J. et al. A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1. Nat. Genet. 39, 207-211 (2007)
-
(2007)
Nat. Genet.
, vol.39
, pp. 207-211
-
-
Hampe, J.1
-
93
-
-
61549115034
-
Diverse genome-wide association studies associate the IL12/IL23 pathway with Crohn disease
-
Wang, K. et al., Diverse genome-wide association studies associate the IL12/IL23 pathway with Crohn disease. Am. J. Hum. Genet. 84, 399-405 (2009)
-
(2009)
Am. J. Hum. Genet.
, vol.84
, pp. 399-405
-
-
Wang, K.1
-
94
-
-
48349136889
-
Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease
-
Barrett, J. C. et al. Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease. Nat. Genet. 40, 955-962 (2008)
-
(2008)
Nat. Genet.
, vol.40
, pp. 955-962
-
-
Barrett, J.C.1
-
95
-
-
44349136821
-
Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease
-
Fisher, S. A. et al. Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease. Nat. Genet. 40, 710-712 (2008)
-
(2008)
Nat. Genet.
, vol.40
, pp. 710-712
-
-
Fisher, S.A.1
-
96
-
-
78649489009
-
Genome-wide meta-Analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
-
Franke, A. et al. Genome-wide meta-Analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. Nat. Genet. 42, 1118-1125 (2010)
-
(2010)
Nat. Genet.
, vol.42
, pp. 1118-1125
-
-
Franke, A.1
-
97
-
-
77950298959
-
Genome-wide association identifies multiple ulcerative colitis susceptibility loci
-
McGovern, D. P. B. et al. Genome-wide association identifies multiple ulcerative colitis susceptibility loci. Nat. Genet. 42, 332-337 (2010)
-
(2010)
Nat. Genet.
, vol.42
, pp. 332-337
-
-
McGovern, D.P.B.1
-
98
-
-
79952195585
-
Meta-Analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47
-
Anderson, C. A. et al. Meta-Analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47. Nat. Genet. 43, 246-252 (2011)
-
(2011)
Nat. Genet.
, vol.43
, pp. 246-252
-
-
Anderson, C.A.1
-
99
-
-
79851490741
-
A meta-Analysis of genome-wide association scans identifies IL18RAP, PTPN2, TAGAP, and PUS10 as shared risk loci for Crohn's disease and celiac disease
-
Festen, E. A. et al. A meta-Analysis of genome-wide association scans identifies IL18RAP, PTPN2, TAGAP, and PUS10 as shared risk loci for Crohn's disease and celiac disease. PLoS Genet. 7, e1001283 (2011)
-
(2011)
Plos Genet.
, vol.7
-
-
Festen, E.A.1
-
100
-
-
79952134938
-
A synonymous variant in IRGM alters a binding site for miR 196 and causes deregulation of IRGM-dependent xenophagy in Crohn's disease
-
Brest, P.et al. A synonymous variant in IRGM alters a binding site for miR 196 and causes deregulation of IRGM-dependent xenophagy in Crohn's disease. Nat. Genet. 43, 242-245 (2011)
-
(2011)
Nat. Genet.
, vol.43
, pp. 242-245
-
-
Brest, P.1
-
101
-
-
50449091647
-
Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease
-
McCarroll, S. A. et al. Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease. Nat. Genet. 40, 1107-1112 (2008)
-
(2008)
Nat. Genet.
, vol.40
, pp. 1107-1112
-
-
McCarroll, S.A.1
-
102
-
-
80051483002
-
Distinct and overlapping genetic loci in Crohn's disease and ulcerative colitis: Correlations with pathogenesis
-
Waterman, M. et al. Distinct and overlapping genetic loci in Crohn's disease and ulcerative colitis: Correlations with pathogenesis. Inflamm. Bowel Dis. 17, 1936-1942 (2010)
-
(2010)
Inflamm. Bowel Dis.
, vol.17
, pp. 1936-1942
-
-
Waterman, M.1
-
103
-
-
78249242440
-
Evidence for significant overlap between common risk variants for Crohn's disease and ankylosing spondylitis
-
Laukens, D. et al. Evidence for significant overlap between common risk variants for Crohn's disease and ankylosing spondylitis. PLoS ONE 5, e13795 (2010)
-
(2010)
Plos One
, vol.5
-
-
Laukens, D.1
-
104
-
-
78651225855
-
Resequencing of positional candidates identifies low frequency IL23R coding variants protecting against inflammatory bowel disease
-
Momozawa, Y. et al. Resequencing of positional candidates identifies low frequency IL23R coding variants protecting against inflammatory bowel disease. Nat. Genet. 43, 43-47 (2011)
-
(2011)
Nat. Genet.
, vol.43
, pp. 43-47
-
-
Momozawa, Y.1
-
105
-
-
33748558056
-
A chromosome 8 gene-cluster polymorphism with low human beta-defensin 2 gene copy number predisposes to Crohn disease of the colon
-
Fellermann, K. et al. A chromosome 8 gene-cluster polymorphism with low human beta-defensin 2 gene copy number predisposes to Crohn disease of the colon. Am. J. Hum. Genet. 79, 439-448 (2006)
-
(2006)
Am. J. Hum. Genet.
, vol.79
, pp. 439-448
-
-
Fellermann, K.1
-
106
-
-
37549033125
-
Psoriasis is associated with increased β-defensin genomic copy number
-
Hollox, E. J. et al. Psoriasis is associated with increased β-defensin genomic copy number. Nat. Genet. 40, 23-25 (2008)
-
(2008)
Nat. Genet.
, vol.40
, pp. 23-25
-
-
Hollox, E.J.1
-
107
-
-
79957471451
-
The niddk ibd genetics consortium. Improved risk prediction for Crohn's disease with a multi-locus approach
-
Kang, J. et al. The NIDDK IBD Genetics Consortium. Improved risk prediction for Crohn's disease with a multi-locus approach. Hum. Mol. Genet. 20, 2435-2442 (2011)
-
(2011)
Hum. Mol. Genet.
, vol.20
, pp. 2435-2442
-
-
Kang, J.1
|