The chromosome 16q region associated with ankylosing spondylitis includes the candidate gene tumour necrosis factor receptor type 1-associated death domain (TRADD)

Annals of the Rheumatic Diseases

Volumn 69, Issue 6, 2010, Pages 1243-1246

  Pointon, Jennifer J ^a   Harvey, David ^a   Karaderi, Tugce ^a   Appleton, Louise H ^a   Farrar, Claire ^a   Stone, Millicent A ^b   Sturrock, Roger D ^c   Reveille, John D ^d   Weisman, Michael H ^e   Ward, Michael M ^f   Brown, Matthew A ^a,g   Wordsworth, B Paul ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b ROYAL NATIONAL HOSPITAL FOR RHEUMATIC DISEASES   (United Kingdom)

^c UNIVERSITY OF GLASGOW   (United Kingdom)

^d UNIVERSITY OF TEXAS   (United States)

^e CEDARS SINAI MEDICAL CENTER   (United States)

^f NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES   (United States)

^g UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED DEATH DOMAIN PROTEIN;

ANKYLOSING SPONDYLITIS; ARTICLE; CHROMOSOME 16Q; CONFIDENCE INTERVAL; CONTROLLED STUDY; GENE FREQUENCY; GENE IDENTIFICATION; GENETIC ASSOCIATION; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM;

CASE-CONTROL STUDIES; CHROMOSOMES, HUMAN, PAIR 16; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; HUMANS; POLYMORPHISM, SINGLE NUCLEOTIDE; SPONDYLITIS, ANKYLOSING; TNF RECEPTOR-ASSOCIATED DEATH DOMAIN PROTEIN;

EID: 77953702946     PISSN: 00034967     EISSN: 14682060     Source Type: Journal    
DOI: 10.1136/ard.2009.115147     Document Type: Article

References (18)

1. Brown MA, Laval SH, Brophy S, et al. Recurrence risk modelling of the genetic susceptibility to ankylosing spondylitis. Ann Rheum Dis 2000;59:883-6.
2. Carter KW, Pluzhnikov A, Timms AE, et al. Combined analysis of three whole genome linkage scans for Ankylosing Spondylitis. Rheumatology (Oxford) 2007;46:763-71.
3. Wellcome Trust Case Control Consortium and The Australo-Anglo-American Spondylitis Consortium. Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants. Nat Genet 2007;39:1329-37.
4. Rahman P, Inman RD, Gladman DD, et al. Association of interleukin-23 receptor variants with ankylosing spondylitis. Arthritis Rheum 2008;58:1020-5.
5. Rueda B, Orozco G, Raya E, et al. The IL23R Arg381Gln non-synonymous polymorphism confers susceptibility to ankylosing spondylitis. Ann Rheum Dis 2008;67:1451-4.
6. Karaderi T, Harvey D, Farrar C, et al. Association between the interleukin 23 receptor and ankylosing spondylitis is confirmed by a new UK case-control study and metaanalysis of published series. Rheumatology (Oxford) 2009;48:386-9.
7. Matsuzaka Y, Okamoto K, Mabuchi T, et al. Identification, expression analysis and polymorphism of a novel RLTPR gene encoding a RGD motif, tropomodulin domain and proline/leucine-rich regions. Gene 2004;343:291-304.
8. Reveille JD, Sims A-M, Maksymowych WP, et al. Genomewide association study in ankylosing spondylitis identifies major non-MHC genetic determinants of disease susceptibility. Clin Exp Rheumatol Suppl 2008;26:723.
9. Hsu H, Xiong J, Goeddel DV. The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation. Cell 1995;81:495-504.
10. Majumder P, Gomez JA, Chadwick BP, et al. The insulator factor CTCF controls MHC class II gene expression and is required for the formation of long-distance chromatin interactions. J Exp Med 2008;205:785-98.
11. Boyle LH, Goodall JC, Opat SS, et al. The recognition of HLA-B27 by human CD4(+) T lymphocytes. J Immunol 2001;167:2619-24.
12. Gauderman WJ. Sample size requirements for matched case-control studies of gene-environment interaction. Stat Med 2002;21:35-50. (Pubitemid 34065703)
13. Abecasis GR, Cookson WO. GOLD - graphical overview of linkage disequilibrium. Bioinformatics 2000;16:182-3.
14. Barrett JC, Fry B, Maller J, et al. Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 2005;21:263-5. (Pubitemid 40202029)
15. Laval SH, Timms A, Edwards S, et al. Whole-genome screening in ankylosing spondylitis: evidence of non-MHC genetic-susceptibility loci. Am J Hum Genet 2001;68:918-26.
16. The International HapMap Consortium. The International HapMap Project. Nature 2003;426:789-96.
17. Ermolaeva MA, Michallet MC, Papadopoulou N, et al. Function of TRADD in tumor necrosis factor receptor 1 signaling and in TRIF-dependent inflammatory responses. Nat Immunol 2008;9:1037-46.
18. Pobezinskaya YL, Kim YS, Choksi S, et al. The function of TRADD in signaling through tumor necrosis factor receptor 1 and TRIF-dependent Toll-like receptors. Nat Immunol 2008;9:1047-54.