메뉴 건너뛰기




Volumn 10, Issue 3, 2009, Pages 201-209

Genome-wide association scan yields new insights into the immunopathogenesis of psoriasis

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; GENE PRODUCT; HLA C ANTIGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 12P40; INTERLEUKIN 13; INTERLEUKIN 17; INTERLEUKIN 23 RECEPTOR; INTERLEUKIN 4; MESSENGER RNA; PROTEIN TNFAIP3; PROTEIN TNIP1; UNCLASSIFIED DRUG;

EID: 67349236684     PISSN: 14664879     EISSN: 14765470     Source Type: Journal    
DOI: 10.1038/gene.2009.11     Document Type: Review
Times cited : (127)

References (98)
  • 4
    • 0028340557 scopus 로고
    • Natural history of psoriatic arthritis
    • Gladman DD. Natural history of psoriatic arthritis. Baillieres Clin Rheumatol 1994; 8: 379-394.
    • (1994) Baillieres Clin Rheumatol , vol.8 , pp. 379-394
    • Gladman, D.D.1
  • 5
    • 49349083936 scopus 로고    scopus 로고
    • Psoriasis
    • Wolff K, Goldsmith LA, Katz SI, Gilchrest BA, Paller AM, Leffell DJ eds, McGraw-Hill: New York
    • Gudjonsson JE, Elder JT. Psoriasis. In: Wolff K, Goldsmith LA, Katz SI, Gilchrest BA, Paller AM, Leffell DJ (eds). Fitzpatrick's Dermatology in General Medicine, vol. 1 McGraw-Hill: New York, 2007, pp 169-194.
    • (2007) Fitzpatrick's Dermatology in General Medicine , vol.1 , pp. 169-194
    • Gudjonsson, J.E.1    Elder, J.T.2
  • 9
    • 0021806161 scopus 로고
    • Psoriasis of early and late onset: Characterization of two types of psoriasis vulgaris
    • Henseler T, Christophers E. Psoriasis of early and late onset: characterization of two types of psoriasis vulgaris. J Am Acad Dermatol 1985; 13: 450-456.
    • (1985) J Am Acad Dermatol , vol.13 , pp. 450-456
    • Henseler, T.1    Christophers, E.2
  • 11
    • 47349085957 scopus 로고    scopus 로고
    • Recurrence risk of psoriatic arthritis (PsA) and psoriasis (Ps) in relatives of patients with PsA (abstract)
    • Chandran V, Pellett FJ, Shanmugarajah S, Schentag CT, Brockbank J, Toloza S et al. Recurrence risk of psoriatic arthritis (PsA) and psoriasis (Ps) in relatives of patients with PsA (abstract). Arthritis Rheum 2007; 56(Suppl 9): S798.
    • (2007) Arthritis Rheum , vol.56 , Issue.SUPPL. 9
    • Chandran, V.1    Pellett, F.J.2    Shanmugarajah, S.3    Schentag, C.T.4    Brockbank, J.5    Toloza, S.6
  • 13
    • 7844244332 scopus 로고    scopus 로고
    • HLA class I and II alleles and susceptibility to generalized pustular psoriasis: Significant associations with HLA-Cw1 and HLA-DQB1*0303
    • Ozawa A, Miyahara M, Sugai J, Iizuka M, Kawakubo Y, Matsuo I et al HLA class I and II alleles and susceptibility to generalized pustular psoriasis: Significant associations with HLA-Cw1 and HLA-DQB1*0303. J Dermatol 1998; 25: 573-581.
    • (1998) J Dermatol , vol.25 , pp. 573-581
    • Ozawa, A.1    Miyahara, M.2    Sugai, J.3    Iizuka, M.4    Kawakubo, Y.5    Matsuo, I.6
  • 14
    • 0028219035 scopus 로고
    • Genetic polymorphisms in HLA-A, -B, -C and -DR antigens in Japanese patients with palmoplantar pustulosis
    • Torii H, Nakagawa H, Ishibashi Y, Tokunaga K, Juji T. Genetic polymorphisms in HLA-A, -B, -C and -DR antigens in Japanese patients with palmoplantar pustulosis. Dermatology 1994; 188: 290-292.
    • (1994) Dermatology , vol.188 , pp. 290-292
    • Torii, H.1    Nakagawa, H.2    Ishibashi, Y.3    Tokunaga, K.4    Juji, T.5
  • 16
    • 34948909646 scopus 로고    scopus 로고
    • Human TH17 lymphocytes promote blood-brain barrier disruption and central nervous system inflammation
    • Kebir H, Kreymborg K, Ifergan I, Dodelet-Devillers A, Cayrol R, Bernard M et al. Human TH17 lymphocytes promote blood-brain barrier disruption and central nervous system inflammation. Nat Med 2007; 13: 1173-1175.
    • (2007) Nat Med , vol.13 , pp. 1173-1175
    • Kebir, H.1    Kreymborg, K.2    Ifergan, I.3    Dodelet-Devillers, A.4    Cayrol, R.5    Bernard, M.6
  • 17
    • 33846036986 scopus 로고    scopus 로고
    • IL-23: A master regulator in Crohn disease
    • Neurath MF. IL-23: A master regulator in Crohn disease. Nat Med 2007; 13: 26-28.
    • (2007) Nat Med , vol.13 , pp. 26-28
    • Neurath, M.F.1
  • 18
    • 33846906224 scopus 로고    scopus 로고
    • Interleukin-22, a T(H)17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis
    • Zheng Y, Danilenko DM, Valdez P, Kasman I, Eastham-Anderson J, Wu J et al. Interleukin-22, a T(H)17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis. Nature 2007; 445: 648-651.
    • (2007) Nature , vol.445 , pp. 648-651
    • Zheng, Y.1    Danilenko, D.M.2    Valdez, P.3    Kasman, I.4    Eastham-Anderson, J.5    Wu, J.6
  • 19
    • 38849187386 scopus 로고    scopus 로고
    • IL-22 is required for Th17 cell-mediated pathology in a mouse model of psoriasis-like skin inflammation
    • Ma HL, Liang S, Li J, Napierata L, Brown T, Benoit S et al. IL-22 is required for Th17 cell-mediated pathology in a mouse model of psoriasis-like skin inflammation. J Clin Invest 2008; 118: 597-607.
    • (2008) J Clin Invest , vol.118 , pp. 597-607
    • Ma, H.L.1    Liang, S.2    Li, J.3    Napierata, L.4    Brown, T.5    Benoit, S.6
  • 21
    • 33846940253 scopus 로고    scopus 로고
    • The effects of IL-20 subfamily cytokines on reconstituted human epidermis suggest potential roles in cutaneous innate defense and pathogenic adaptive immunity in psoriasis
    • Sa SM, Valdez PA, Wu J, Jung K, Zhong F, Hall L et al. The effects of IL-20 subfamily cytokines on reconstituted human epidermis suggest potential roles in cutaneous innate defense and pathogenic adaptive immunity in psoriasis. J Immunol 2007; 178: 2229-2240.
    • (2007) J Immunol , vol.178 , pp. 2229-2240
    • Sa, S.M.1    Valdez, P.A.2    Wu, J.3    Jung, K.4    Zhong, F.5    Hall, L.6
  • 22
    • 33646552450 scopus 로고    scopus 로고
    • IL-22 regulates the expression of genes responsible for antimicrobial defense, cellular differentiation, and mobility in keratinocytes: A potential role in psoriasis
    • Wolk K, Witte E, Wallace E, Docke WD, Kunz S, Asadullah K et al. IL-22 regulates the expression of genes responsible for antimicrobial defense, cellular differentiation, and mobility in keratinocytes: A potential role in psoriasis. Eur J Immunol 2006; 36: 1309-1323.
    • (2006) Eur J Immunol , vol.36 , pp. 1309-1323
    • Wolk, K.1    Witte, E.2    Wallace, E.3    Docke, W.D.4    Kunz, S.5    Asadullah, K.6
  • 23
    • 0036604122 scopus 로고    scopus 로고
    • Cutting edge: Immune cells as sources and targets of the IL-10 family members?
    • Wolk K, Kunz S, Asadullah K, Sabat R. Cutting edge: Immune cells as sources and targets of the IL-10 family members? J Immunol 2002; 168: 5397-5402.
    • (2002) J Immunol , vol.168 , pp. 5397-5402
    • Wolk, K.1    Kunz, S.2    Asadullah, K.3    Sabat, R.4
  • 24
    • 58149316658 scopus 로고    scopus 로고
    • Induction of memory IL-17+ T cell trafficking and expansion by IFN-gamma: Mechanism and pathological relevance
    • Kryczek I, Bruce AT, Gudjonsson JE, Johnston A, Vatan L, Szeliga W et al. Induction of memory IL-17+ T cell trafficking and expansion by IFN-gamma: Mechanism and pathological relevance. J Immunol 2008; 181: 4733-4741.
    • (2008) J Immunol , vol.181 , pp. 4733-4741
    • Kryczek, I.1    Bruce, A.T.2    Gudjonsson, J.E.3    Johnston, A.4    Vatan, L.5    Szeliga, W.6
  • 25
    • 34447124969 scopus 로고    scopus 로고
    • Alpha1beta1 integrin is crucial for accumulation of epidermal T cells and the development of psoriasis
    • Conrad C, Boyman O, Tonel G, Tun-Kyi A, Laggner U, de Fougerolles A et al. Alpha1beta1 integrin is crucial for accumulation of epidermal T cells and the development of psoriasis. Nat Med 2007; 13: 836-842.
    • (2007) Nat Med , vol.13 , pp. 836-842
    • Conrad, C.1    Boyman, O.2    Tonel, G.3    Tun-Kyi, A.4    Laggner, U.5    de Fougerolles, A.6
  • 27
    • 34548340684 scopus 로고    scopus 로고
    • New models of collaboration in genome-wide association studies: The Genetic Association Information Network
    • Manolio TA, Rodriguez LL, Brooks L, Abecasis G, Ballinger D, Daly M et al. New models of collaboration in genome-wide association studies: The Genetic Association Information Network. Nat Genet 2007; 39: 1045-1051.
    • (2007) Nat Genet , vol.39 , pp. 1045-1051
    • Manolio, T.A.1    Rodriguez, L.L.2    Brooks, L.3    Abecasis, G.4    Ballinger, D.5    Daly, M.6
  • 28
    • 59149106117 scopus 로고    scopus 로고
    • Genome-wide scan reveals association of psoriasis with IL-23 and NF-kB pathways
    • Nair RP, Callis Duffin K, Helms C, Ding J, Stuart PE, Goldgar D et al Genome-wide scan reveals association of psoriasis with IL-23 and NF-kB pathways. Nat Genet 2009; 41: 199-204.
    • (2009) Nat Genet , vol.41 , pp. 199-204
    • Nair, R.P.1    Callis Duffin, K.2    Helms, C.3    Ding, J.4    Stuart, P.E.5    Goldgar, D.6
  • 30
    • 33645023965 scopus 로고    scopus 로고
    • Distinct clinical differences between HLA-Cw*0602 positive and negative psoriasis patients - an analysis of 1019 HLA-C- and HLA-B-typed patients
    • Gudjonsson JE, Karason A, Runarsdottir EH, Antonsdottir AA, Hauksson VB, Jonsson HH et al. Distinct clinical differences between HLA-Cw*0602 positive and negative psoriasis patients - an analysis of 1019 HLA-C- and HLA-B-typed patients. J Invest Dermatol 2006; 126: 740-745.
    • (2006) J Invest Dermatol , vol.126 , pp. 740-745
    • Gudjonsson, J.E.1    Karason, A.2    Runarsdottir, E.H.3    Antonsdottir, A.A.4    Hauksson, V.B.5    Jonsson, H.H.6
  • 31
    • 12244281852 scopus 로고    scopus 로고
    • Interleukin-12 p40 gene (IL12B) 3′-untranslated region polymorphism is associated with susceptibility to atopic dermatitis and psoriasis vulgaris
    • Tsunemi Y, Saeki H, Nakamura K, Sekiya T, Hirai K, Fujita H et al. Interleukin-12 p40 gene (IL12B) 3′-untranslated region polymorphism is associated with susceptibility to atopic dermatitis and psoriasis vulgaris. J Dermatol Sci 2002; 30: 161-166.
    • (2002) J Dermatol Sci , vol.30 , pp. 161-166
    • Tsunemi, Y.1    Saeki, H.2    Nakamura, K.3    Sekiya, T.4    Hirai, K.5    Fujita, H.6
  • 32
    • 34547774225 scopus 로고    scopus 로고
    • Sequence variants in the genes for the interleukin-23 receptor (IL23R) and its ligand (IL12B) confer protection against psoriasis
    • Capon F, Di Meglio P, Szaub J, Prescott NJ, Dunster C, Baumber L et al. Sequence variants in the genes for the interleukin-23 receptor (IL23R) and its ligand (IL12B) confer protection against psoriasis. Hum Genet 2007; 122: 201-206.
    • (2007) Hum Genet , vol.122 , pp. 201-206
    • Capon, F.1    Di Meglio, P.2    Szaub, J.3    Prescott, N.J.4    Dunster, C.5    Baumber, L.6
  • 33
    • 33846608131 scopus 로고    scopus 로고
    • A large-scale genetic association study confirms IL12B and leads to the identification of IL23R as psoriasis-risk genes
    • Cargill M, Schrodi SJ, Chang M, Garcia VE, Brandon R, Callis KP et al A large-scale genetic association study confirms IL12B and leads to the identification of IL23R as psoriasis-risk genes. Am J Hum Genet 2007; 80: 273-290.
    • (2007) Am J Hum Genet , vol.80 , pp. 273-290
    • Cargill, M.1    Schrodi, S.J.2    Chang, M.3    Garcia, V.E.4    Brandon, R.5    Callis, K.P.6
  • 34
    • 0027032474 scopus 로고
    • A role of tonsillar lymphocyte for focal infection. With special reference to lymphocyte adhesion to vessels in dermis
    • Akagi Y, Kimura T, Kunimoto M, Kuki K, Tabata T. A role of tonsillar lymphocyte for focal infection. With special reference to lymphocyte adhesion to vessels in dermis. Adv Otorhinolaryngol 1992; 47 129-133.
    • (1992) Adv Otorhinolaryngol , vol.47 , pp. 129-133
    • Akagi, Y.1    Kimura, T.2    Kunimoto, M.3    Kuki, K.4    Tabata, T.5
  • 35
    • 33646887838 scopus 로고    scopus 로고
    • Identical TCR beta-chain rearrangements in streptococcal angina and skin lesions of patients with psoriasis vulgaris
    • Diluvio L, Vollmer S, Besgen P, Ellwart JW, Chimenti S, Prinz JC. Identical TCR beta-chain rearrangements in streptococcal angina and skin lesions of patients with psoriasis vulgaris. J Immunol 2006; 176: 7104-7111.
    • (2006) J Immunol , vol.176 , pp. 7104-7111
    • Diluvio, L.1    Vollmer, S.2    Besgen, P.3    Ellwart, J.W.4    Chimenti, S.5    Prinz, J.C.6
  • 37
    • 0032825299 scopus 로고    scopus 로고
    • Selection of conserved TCR VDJ rearrangements in chronic psoriatic plaques indicates a common antigen in psoriasis vulgaris
    • Prinz JC, Vollmer S, Boehncke WH, Menssen A, Laisney I, Trommler P. Selection of conserved TCR VDJ rearrangements in chronic psoriatic plaques indicates a common antigen in psoriasis vulgaris. Eur J Immunol 1999; 29: 3360-3368.
    • (1999) Eur J Immunol , vol.29 , pp. 3360-3368
    • Prinz, J.C.1    Vollmer, S.2    Boehncke, W.H.3    Menssen, A.4    Laisney, I.5    Trommler, P.6
  • 38
    • 0035726290 scopus 로고    scopus 로고
    • Dominant lesional T cell receptor rearrangements persist in relapsing psoriasis but are absent from nonlesional skin: Evidence for a stable antigen-specific pathogenic T cell response in psoriasis vulgaris
    • Vollmer S, Menssen A, Prinz JC. Dominant lesional T cell receptor rearrangements persist in relapsing psoriasis but are absent from nonlesional skin: Evidence for a stable antigen-specific pathogenic T cell response in psoriasis vulgaris. J Invest Dermatol 2001; 117: 1296-1301.
    • (2001) J Invest Dermatol , vol.117 , pp. 1296-1301
    • Vollmer, S.1    Menssen, A.2    Prinz, J.C.3
  • 41
    • 4644291450 scopus 로고    scopus 로고
    • Peripheral blood T cell responses to keratin peptides that share sequences with streptococcal M proteins are largely restricted to skin-homing CD8(+) T cells
    • Johnston A, Gudjonsson JE, Sigmundsdottir H, Love TJ, Valdimarsson H. Peripheral blood T cell responses to keratin peptides that share sequences with streptococcal M proteins are largely restricted to skin-homing CD8(+) T cells. Clin Exp Immunol 2004; 138: 83-93.
    • (2004) Clin Exp Immunol , vol.138 , pp. 83-93
    • Johnston, A.1    Gudjonsson, J.E.2    Sigmundsdottir, H.3    Love, T.J.4    Valdimarsson, H.5
  • 43
    • 33750844031 scopus 로고    scopus 로고
    • Peptidoglycan: A major aetiological factor for psoriasis?
    • Baker BS, Powles A, Fry L. Peptidoglycan: A major aetiological factor for psoriasis? Trends Immunol 2006; 27: 545-551.
    • (2006) Trends Immunol , vol.27 , pp. 545-551
    • Baker, B.S.1    Powles, A.2    Fry, L.3
  • 44
    • 23844450075 scopus 로고    scopus 로고
    • Activating killer cell immunoglobulin-like receptor gene KIR2DS1 is associated with psoriatic arthritis
    • Williams F, Meenagh A, Sleator C, Cook D, Fernandez-Vina M, Bowcock AM et al. Activating killer cell immunoglobulin-like receptor gene KIR2DS1 is associated with psoriatic arthritis. Hum Immunol 2005; 66: 836-841.
    • (2005) Hum Immunol , vol.66 , pp. 836-841
    • Williams, F.1    Meenagh, A.2    Sleator, C.3    Cook, D.4    Fernandez-Vina, M.5    Bowcock, A.M.6
  • 45
    • 4644229910 scopus 로고    scopus 로고
    • Cutting edge: Heterozygote advantage in Hutoimmune disease: hierarchy of protection/susceptibility conferred by HLA and killer Ig-like receptor combinations in psoriatic arthritis
    • Nelson GW, Martin MP, Gladman D, Wade J, Trowsdale J, Carrington M. Cutting edge: Heterozygote advantage in Hutoimmune disease: hierarchy of protection/susceptibility conferred by HLA and killer Ig-like receptor combinations in psoriatic arthritis. J Immunol 2004; 173: 4273-4276.
    • (2004) J Immunol , vol.173 , pp. 4273-4276
    • Nelson, G.W.1    Martin, M.P.2    Gladman, D.3    Wade, J.4    Trowsdale, J.5    Carrington, M.6
  • 46
    • 0034118122 scopus 로고    scopus 로고
    • HLA class I recognition by killer cell Ig-like receptors
    • Long EO, Rajagopalan S. HLA class I recognition by killer cell Ig-like receptors. Semin Immunol 2000; 12: 101-108.
    • (2000) Semin Immunol , vol.12 , pp. 101-108
    • Long, E.O.1    Rajagopalan, S.2
  • 47
    • 0347285359 scopus 로고    scopus 로고
    • Increased expression of interleukin 23 p19 and p40 in lesional skin of patients with psoriasis vulgaris
    • Lee E, Trepicchio WL, Oestreicher JL, Pittman D, Wang F, Chamian F et al. Increased expression of interleukin 23 p19 and p40 in lesional skin of patients with psoriasis vulgaris. J Exp Med 2004; 199 125-130.
    • (2004) J Exp Med , vol.199 , pp. 125-130
    • Lee, E.1    Trepicchio, W.L.2    Oestreicher, J.L.3    Pittman, D.4    Wang, F.5    Chamian, F.6
  • 48
    • 34248572345 scopus 로고    scopus 로고
    • T(H)-17 cells in the circle of immunity and autoimmunity
    • Bettelli E, Oukka M, Kuchroo VK. T(H)-17 cells in the circle of immunity and autoimmunity. Nat Immunol 2007; 8: 345-350.
    • (2007) Nat Immunol , vol.8 , pp. 345-350
    • Bettelli, E.1    Oukka, M.2    Kuchroo, V.K.3
  • 49
    • 33845340501 scopus 로고    scopus 로고
    • A genome-wide association study identifies IL23R as an inflammatory bowel disease gene
    • Duerr RH, Taylor KD, Brant SR, Rioux JD, Silverberg MS, Daly MJ et al A genome-wide association study identifies IL23R as an inflammatory bowel disease gene. Science 2006; 314: 1461-1463.
    • (2006) Science , vol.314 , pp. 1461-1463
    • Duerr, R.H.1    Taylor, K.D.2    Brant, S.R.3    Rioux, J.D.4    Silverberg, M.S.5    Daly, M.J.6
  • 50
    • 0038793719 scopus 로고    scopus 로고
    • Connections between psoriasis and Crohn's disease
    • quiz 822-804
    • Najarian DJ, Gottlieb AB. Connections between psoriasis and Crohn's disease. J Am Acad Dermatol 2003; 48: 805-821; quiz 822-804.
    • (2003) J Am Acad Dermatol , vol.48 , pp. 805-821
    • Najarian, D.J.1    Gottlieb, A.B.2
  • 51
    • 33745856562 scopus 로고    scopus 로고
    • ABIN-1 binds to NEMO/IKKgamma and co-operates with A20 in inhibiting NF-kappaB
    • Mauro C, Pacifico F, Lavorgna A, Mellone S, Iannetti A, Acquaviva R et al. ABIN-1 binds to NEMO/IKKgamma and co-operates with A20 in inhibiting NF-kappaB. J Biol Chem 2006; 281: 18482-18488.
    • (2006) J Biol Chem , vol.281 , pp. 18482-18488
    • Mauro, C.1    Pacifico, F.2    Lavorgna, A.3    Mellone, S.4    Iannetti, A.5    Acquaviva, R.6
  • 52
    • 33751546237 scopus 로고    scopus 로고
    • IL-23 stimulates epidermal hyperplasia via TNF and IL-20R2-dependent mechanisms with implications for psoriasis pathogenesis
    • Chan JR, Blumenschein W, Murphy E, Diveu C, Wiekowski M, Abbondanzo S et al. IL-23 stimulates epidermal hyperplasia via TNF and IL-20R2-dependent mechanisms with implications for psoriasis pathogenesis. J Exp Med 2006; 203: 2577-2587.
    • (2006) J Exp Med , vol.203 , pp. 2577-2587
    • Chan, J.R.1    Blumenschein, W.2    Murphy, E.3    Diveu, C.4    Wiekowski, M.5    Abbondanzo, S.6
  • 53
    • 45949098797 scopus 로고    scopus 로고
    • A 9-centimorgan interval of chromosome 10 controls the T cell-dependent psoriasiform skin disease and arthritis in a murine psoriasis model
    • Wang H, Kess D, Lindqvist AK, Peters T, Sindrilaru A, Wlaschek M et al. A 9-centimorgan interval of chromosome 10 controls the T cell-dependent psoriasiform skin disease and arthritis in a murine psoriasis model. J Immunol 2008; 180: 5520-5529.
    • (2008) J Immunol , vol.180 , pp. 5520-5529
    • Wang, H.1    Kess, D.2    Lindqvist, A.K.3    Peters, T.4    Sindrilaru, A.5    Wlaschek, M.6
  • 54
    • 0345060875 scopus 로고    scopus 로고
    • A20, a regulator of NFkappaB, maps to an atherosclerosis locus and differs between parental sensitive C57BL/6J and resistant FVB/N strains
    • Idel S, Dansky HM, Breslow JL. A20, a regulator of NFkappaB, maps to an atherosclerosis locus and differs between parental sensitive C57BL/6J and resistant FVB/N strains. Proc Natl Acad Sci USA 2003; 100 14235-14240.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 14235-14240
    • Idel, S.1    Dansky, H.M.2    Breslow, J.L.3
  • 56
    • 50449111452 scopus 로고    scopus 로고
    • Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus
    • Graham RR, Cotsapas C, Davies L, Hackett R, Lessard CJ, Leon JM et al Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus. Nat Genet 2008; 40: 1059-1061.
    • (2008) Nat Genet , vol.40 , pp. 1059-1061
    • Graham, R.R.1    Cotsapas, C.2    Davies, L.3    Hackett, R.4    Lessard, C.J.5    Leon, J.M.6
  • 57
    • 50449103533 scopus 로고    scopus 로고
    • Multiple polymorphisms in the TNFAIP3 region are independently associated with systemic lupus erythematosus
    • Musone SL, Taylor KE, Lu TT, Nititham J, Ferreira RC, Ortmann W et al Multiple polymorphisms in the TNFAIP3 region are independently associated with systemic lupus erythematosus. Nat Genet 2008; 40: 1062-1064.
    • (2008) Nat Genet , vol.40 , pp. 1062-1064
    • Musone, S.L.1    Taylor, K.E.2    Lu, T.T.3    Nititham, J.4    Ferreira, R.C.5    Ortmann, W.6
  • 60
    • 34447539622 scopus 로고    scopus 로고
    • Pathogenesis and clinical features of psoriasis
    • Griffiths CE, Barker JN. Pathogenesis and clinical features of psoriasis. Lancet 2007; 370: 263-271.
    • (2007) Lancet , vol.370 , pp. 263-271
    • Griffiths, C.E.1    Barker, J.N.2
  • 61
    • 0037234390 scopus 로고    scopus 로고
    • Interleukin-4 therapy of psoriasis induces Th2 responses and improves human autoimmune disease
    • Ghoreschi K, Thomas P, Breit S, Dugas M, Mailhammer R, van Eden W et al. Interleukin-4 therapy of psoriasis induces Th2 responses and improves human autoimmune disease. Nat Med 2003; 9: 40-46.
    • (2003) Nat Med , vol.9 , pp. 40-46
    • Ghoreschi, K.1    Thomas, P.2    Breit, S.3    Dugas, M.4    Mailhammer, R.5    van Eden, W.6
  • 62
    • 0037963472 scopus 로고    scopus 로고
    • Regulation of the Th2 cytokine locus by a locus control region
    • Lee GR, Fields PE, Griffin TJ, Flavell RA. Regulation of the Th2 cytokine locus by a locus control region. Immunity 2003; 19: 145-153.
    • (2003) Immunity , vol.19 , pp. 145-153
    • Lee, G.R.1    Fields, P.E.2    Griffin, T.J.3    Flavell, R.A.4
  • 63
    • 0018236825 scopus 로고
    • Alterations of clinically normal skin in early eruptive guttate psoriasis
    • Brody I. Alterations of clinically normal skin in early eruptive guttate psoriasis. J Cutan Pathol 1978; 5: 219-233.
    • (1978) J Cutan Pathol , vol.5 , pp. 219-233
    • Brody, I.1
  • 64
    • 0018552517 scopus 로고
    • Evolution, maturation, and regression of lesions of psoriasis. New observations and correlation of clinical and histologic findings
    • Ragaz A, Ackerman AB. Evolution, maturation, and regression of lesions of psoriasis. New observations and correlation of clinical and histologic findings. Am J Dermatopathol 1979; 1: 199-214.
    • (1979) Am J Dermatopathol , vol.1 , pp. 199-214
    • Ragaz, A.1    Ackerman, A.B.2
  • 65
    • 0021795853 scopus 로고
    • Mast cells and macrophages in early relapsing psoriasis
    • Schubert C, Christophers E. Mast cells and macrophages in early relapsing psoriasis. Arch Dermatol Res 1985; 277: 352-358.
    • (1985) Arch Dermatol Res , vol.277 , pp. 352-358
    • Schubert, C.1    Christophers, E.2
  • 66
    • 0017599305 scopus 로고
    • The dermal inflammatory reaction in initial psoriatic lesions
    • Braun-Falco O, Schmoeckel C. The dermal inflammatory reaction in initial psoriatic lesions. Arch Dermatol Res 1977; 258: 9-16.
    • (1977) Arch Dermatol Res , vol.258 , pp. 9-16
    • Braun-Falco, O.1    Schmoeckel, C.2
  • 67
    • 18744409038 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells: A new cutaneous dendritic cell subset with distinct role in inflammatory skin diseases
    • Wollenberg A, Wagner M, Gunther S, Towarowski A, Tuma E, Moderer M et al. Plasmacytoid dendritic cells: A new cutaneous dendritic cell subset with distinct role in inflammatory skin diseases. J Invest Dermatol 2002; 119: 1096-1102.
    • (2002) J Invest Dermatol , vol.119 , pp. 1096-1102
    • Wollenberg, A.1    Wagner, M.2    Gunther, S.3    Towarowski, A.4    Tuma, E.5    Moderer, M.6
  • 68
    • 22344438901 scopus 로고    scopus 로고
    • Plasmacytoid predendritic cells initiate psoriasis through interferon-{alpha} production
    • Nestle FO, Conrad C, Tun-Kyi A, Homey B, Gombert M, Boyman O et al Plasmacytoid predendritic cells initiate psoriasis through interferon-{alpha} production. J Exp Med 2005; 202: 135-143.
    • (2005) J Exp Med , vol.202 , pp. 135-143
    • Nestle, F.O.1    Conrad, C.2    Tun-Kyi, A.3    Homey, B.4    Gombert, M.5    Boyman, O.6
  • 69
    • 67349219906 scopus 로고    scopus 로고
    • Braun-Falco O. Dynamics of growth and regression in psoriatic lesions: alterations in the skin from normal into a psoriatic lesion, and during regression of psoriatic lesions. In: Farber EM, Cox AJ (eds). Psoriasis: Proceedings of the International Symposium, Stanford University, 1971. Stanford University Press: Stanford, CA, 1971, pp 215-237.
    • Braun-Falco O. Dynamics of growth and regression in psoriatic lesions: alterations in the skin from normal into a psoriatic lesion, and during regression of psoriatic lesions. In: Farber EM, Cox AJ (eds). Psoriasis: Proceedings of the International Symposium, Stanford University, 1971. Stanford University Press: Stanford, CA, 1971, pp 215-237.
  • 70
    • 0028916476 scopus 로고
    • A subset of macrophages located along the basement membrane ('lining cells') is a characteristic histopathological feature of psoriasis
    • Boehncke WH, Wortmann S, Kaufmann R, Mielke V, Sterry W. A subset of macrophages located along the basement membrane ('lining cells') is a characteristic histopathological feature of psoriasis. Am J Dermatopathol 1995; 17: 139-144.
    • (1995) Am J Dermatopathol , vol.17 , pp. 139-144
    • Boehncke, W.H.1    Wortmann, S.2    Kaufmann, R.3    Mielke, V.4    Sterry, W.5
  • 72
    • 0032037673 scopus 로고    scopus 로고
    • Fibronectin and alpha5 integrin regulate keratinocyte cell cycling. A mechanism for increased fibronectin potentiation of T cell lymphokine-driven keratinocyte hyperproliferation in psoriasis
    • Bata-Csorgo Z, Cooper KD, Ting KM, Voorhees JJ, Hammerberg C. Fibronectin and alpha5 integrin regulate keratinocyte cell cycling. A mechanism for increased fibronectin potentiation of T cell lymphokine-driven keratinocyte hyperproliferation in psoriasis. J Clin Invest 1998; 101: 1509-1518.
    • (1998) J Clin Invest , vol.101 , pp. 1509-1518
    • Bata-Csorgo, Z.1    Cooper, K.D.2    Ting, K.M.3    Voorhees, J.J.4    Hammerberg, C.5
  • 73
    • 0021268032 scopus 로고
    • Mast cell degranulation in the evolution of acute eruptive guttate psoriasis vulgaris
    • Brody I. Mast cell degranulation in the evolution of acute eruptive guttate psoriasis vulgaris. J Invest Dermatol 1984; 82: 460-464.
    • (1984) J Invest Dermatol , vol.82 , pp. 460-464
    • Brody, I.1
  • 74
    • 0023683885 scopus 로고
    • Use of monospecific antisera and cRNA probes to localize the major changes in keratin expression during normal and abnormal epidermal differentiation
    • Stoler A, Kopan R, Duvic M, Fuchs E. Use of monospecific antisera and cRNA probes to localize the major changes in keratin expression during normal and abnormal epidermal differentiation. J Cell Biol 1988; 107: 427-446.
    • (1988) J Cell Biol , vol.107 , pp. 427-446
    • Stoler, A.1    Kopan, R.2    Duvic, M.3    Fuchs, E.4
  • 75
    • 0028793640 scopus 로고
    • Keratins (K16 and K17) as markers of keratinocyte hyperproliferation in psoriasis in vivo and in vitro
    • Leigh IM, Navsaria H, Purkis PE, McKay IA, Bowden PE, Riddle PN. Keratins (K16 and K17) as markers of keratinocyte hyperproliferation in psoriasis in vivo and in vitro. Br J Dermatol 1995; 133 501-511.
    • (1995) Br J Dermatol , vol.133 , pp. 501-511
    • Leigh, I.M.1    Navsaria, H.2    Purkis, P.E.3    McKay, I.A.4    Bowden, P.E.5    Riddle, P.N.6
  • 76
    • 0037453146 scopus 로고    scopus 로고
    • Novel mechanisms of T-cell and dendritic cell activation revealed by profiling of psoriasis on the 63 100-element oligonucleotide array
    • Zhou X, Krueger JG, Kao MC, Lee E, Du F, Menter A et al. Novel mechanisms of T-cell and dendritic cell activation revealed by profiling of psoriasis on the 63 100-element oligonucleotide array. Physiol Genomics 2003; 13: 69-78.
    • (2003) Physiol Genomics , vol.13 , pp. 69-78
    • Zhou, X.1    Krueger, J.G.2    Kao, M.C.3    Lee, E.4    Du, F.5    Menter, A.6
  • 77
    • 79959361260 scopus 로고    scopus 로고
    • Global gene expression analysis reveals evidence for decreased lipid biosynthesis and increased innate immunity in uninvolved psoriatic skin
    • submitted
    • Gudjonsson JE, Ding J, Li X, Nair RP, Stuart PE, Tejasvi T et al. Global gene expression analysis reveals evidence for decreased lipid biosynthesis and increased innate immunity in uninvolved psoriatic skin. J Invest Dermatol 2009 (submitted).
    • (2009) J Invest Dermatol
    • Gudjonsson, J.E.1    Ding, J.2    Li, X.3    Nair, R.P.4    Stuart, P.E.5    Tejasvi, T.6
  • 78
    • 0032900956 scopus 로고    scopus 로고
    • Searching for psoriasis susceptibility genes in Italy: Genome scan and evidence for a new locus on chromosome 1
    • Capon F, Novelli G, Semprini S, Clementi M, Nudo M, Vultaggio P et al Searching for psoriasis susceptibility genes in Italy: Genome scan and evidence for a new locus on chromosome 1. J Invest Dermatol 1999; 112: 32-35.
    • (1999) J Invest Dermatol , vol.112 , pp. 32-35
    • Capon, F.1    Novelli, G.2    Semprini, S.3    Clementi, M.4    Nudo, M.5    Vultaggio, P.6
  • 81
    • 0031708739 scopus 로고    scopus 로고
    • The genetics of psoriasis: A complex disorder of the skin and immune system
    • Bhalerao J, Bowcock AM. The genetics of psoriasis: A complex disorder of the skin and immune system. Hum Mol Genet 1998; 7: 1537-1545.
    • (1998) Hum Mol Genet , vol.7 , pp. 1537-1545
    • Bhalerao, J.1    Bowcock, A.M.2
  • 82
    • 59149098800 scopus 로고    scopus 로고
    • Deletion of the late cornified envelope (LCE) 3C and 3B genes as a susceptibility factor for psoriasis
    • de Cid R, Riveira-Munoz E, Zeeuwen PLJM, Robarge J, Liao W, Dannhauser E et al. Deletion of the late cornified envelope (LCE) 3C and 3B genes as a susceptibility factor for psoriasis. Nat Genet 2009; 41: 211-215.
    • (2009) Nat Genet , vol.41 , pp. 211-215
    • de Cid, R.1    Riveira-Munoz, E.2    Zeeuwen, P.L.J.M.3    Robarge, J.4    Liao, W.5    Dannhauser, E.6
  • 84
    • 0035076443 scopus 로고    scopus 로고
    • Potential role of the chemokine receptors CXCR3, CCR4, and the integrin alphaEbeta7 in the pathogenesis of psoriasis vulgaris
    • Rottman JB, Smith TL, Ganley KG, Kikuchi T, Krueger JG. Potential role of the chemokine receptors CXCR3, CCR4, and the integrin alphaEbeta7 in the pathogenesis of psoriasis vulgaris. Lab Invest 2001; 81: 335-347.
    • (2001) Lab Invest , vol.81 , pp. 335-347
    • Rottman, J.B.1    Smith, T.L.2    Ganley, K.G.3    Kikuchi, T.4    Krueger, J.G.5
  • 85
    • 33746760161 scopus 로고    scopus 로고
    • Pathogenic role for skin macrophages in a mouse model of keratinocyte-induced psoriasis-like skin inflammation
    • Stratis A, Pasparakis M, Rupec RA, Markur D, Hartmann K, Scharffetter-Kochanek K et al. Pathogenic role for skin macrophages in a mouse model of keratinocyte-induced psoriasis-like skin inflammation. J Clin Invest 2006; 116: 2094-2104.
    • (2006) J Clin Invest , vol.116 , pp. 2094-2104
    • Stratis, A.1    Pasparakis, M.2    Rupec, R.A.3    Markur, D.4    Hartmann, K.5    Scharffetter-Kochanek, K.6
  • 86
    • 33746766314 scopus 로고    scopus 로고
    • Activated macrophages are essential in a murine model for T cell-mediated chronic psoriasiform skin inflammation
    • Wang H, Peters T, Kess D, Sindrilaru A, Oreshkova T, Van Rooijen N et al. Activated macrophages are essential in a murine model for T cell-mediated chronic psoriasiform skin inflammation. J Clin Invest 2006; 116: 2105-2114.
    • (2006) J Clin Invest , vol.116 , pp. 2105-2114
    • Wang, H.1    Peters, T.2    Kess, D.3    Sindrilaru, A.4    Oreshkova, T.5    Van Rooijen, N.6
  • 87
    • 0028842377 scopus 로고
    • Kinetics and regulation of human keratinocyte stem cell growth in short-term primary ex vivo culture. Cooperative growth factors from psoriatic lesional T lymphocytes stimulate proliferation among psoriatic uninvolved, but not normal, stem keratinocytes
    • Bata-Csorgo Z, Hammerberg C, Voorhees JJ, Cooper KD. Kinetics and regulation of human keratinocyte stem cell growth in short-term primary ex vivo culture. Cooperative growth factors from psoriatic lesional T lymphocytes stimulate proliferation among psoriatic uninvolved, but not normal, stem keratinocytes. J Clin Invest 1995; 95: 317-327.
    • (1995) J Clin Invest , vol.95 , pp. 317-327
    • Bata-Csorgo, Z.1    Hammerberg, C.2    Voorhees, J.J.3    Cooper, K.D.4
  • 88
    • 22144446792 scopus 로고    scopus 로고
    • Cell death-induced activation of epidermal growth factor receptor in keratinocytes: Implications for restricting epidermal damage in dermatitis
    • Iordanov MS, Sundholm AJ, Simpson EL, Hanifin JM, Ryabinina OP, Choi RJ et al. Cell death-induced activation of epidermal growth factor receptor in keratinocytes: Implications for restricting epidermal damage in dermatitis. J Invest Dermatol 2005; 125: 134-142.
    • (2005) J Invest Dermatol , vol.125 , pp. 134-142
    • Iordanov, M.S.1    Sundholm, A.J.2    Simpson, E.L.3    Hanifin, J.M.4    Ryabinina, O.P.5    Choi, R.J.6
  • 89
    • 34249888775 scopus 로고    scopus 로고
    • Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels
    • Saxena R, Voight BF, Lyssenko V, Burtt NP, de Bakker PI, Chen H et al Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. Science 2007; 316: 1331-1336.
    • (2007) Science , vol.316 , pp. 1331-1336
    • Saxena, R.1    Voight, B.F.2    Lyssenko, V.3    Burtt, N.P.4    de Bakker, P.I.5    Chen, H.6
  • 90
    • 38649125868 scopus 로고    scopus 로고
    • Newly identified loci that influence lipid concentrations and risk of coronary artery disease
    • Willer CJ, Sanna S, Jackson AU, Scuteri A, Bonnycastle LL, Clarke R et al. Newly identified loci that influence lipid concentrations and risk of coronary artery disease. Nat Genet 2008; 40: 161-169.
    • (2008) Nat Genet , vol.40 , pp. 161-169
    • Willer, C.J.1    Sanna, S.2    Jackson, A.U.3    Scuteri, A.4    Bonnycastle, L.L.5    Clarke, R.6
  • 91
    • 38649132270 scopus 로고    scopus 로고
    • Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans
    • Kathiresan S, Melander O, Guiducci C, Surti A, Burtt NP, Rieder MJ et al. Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans. Nat Genet 2008; 40: 189-197.
    • (2008) Nat Genet , vol.40 , pp. 189-197
    • Kathiresan, S.1    Melander, O.2    Guiducci, C.3    Surti, A.4    Burtt, N.P.5    Rieder, M.J.6
  • 92
    • 34748830310 scopus 로고    scopus 로고
    • A common variant of HMGA2 is associated with adult and childhood height in the general population
    • Weedon MN, Lettre G, Freathy RM, Lindgren CM, Voight BF, Perry JR et al. A common variant of HMGA2 is associated with adult and childhood height in the general population. Nat Genet 2007; 39: 1245-1250.
    • (2007) Nat Genet , vol.39 , pp. 1245-1250
    • Weedon, M.N.1    Lettre, G.2    Freathy, R.M.3    Lindgren, C.M.4    Voight, B.F.5    Perry, J.R.6
  • 94
  • 95
    • 48349136889 scopus 로고    scopus 로고
    • Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease
    • Barrett JC, Hansoul S, Nicolae DL, Cho JH, Duerr RH, Rioux JD et al Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease. Nat Genet 2008; 40: 955-962.
    • (2008) Nat Genet , vol.40 , pp. 955-962
    • Barrett, J.C.1    Hansoul, S.2    Nicolae, D.L.3    Cho, J.H.4    Duerr, R.H.5    Rioux, J.D.6
  • 96
    • 0035832515 scopus 로고    scopus 로고
    • Efficacy and safety of infliximab monotherapy for plaque-type psoriasis: A randomised trial
    • Chaudhari U, Romano P, Mulcahy LD, Dooley LT, Baker DG, Gottlieb AB. Efficacy and safety of infliximab monotherapy for plaque-type psoriasis: a randomised trial. Lancet 2001; 357: 1842-1847.
    • (2001) Lancet , vol.357 , pp. 1842-1847
    • Chaudhari, U.1    Romano, P.2    Mulcahy, L.D.3    Dooley, L.T.4    Baker, D.G.5    Gottlieb, A.B.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.