Effects of Cyclic Lipodepsipeptide Structural Modulation on Stability, Antibacterial Activity, and Human Cell Toxicity

ChemMedChem

Volumn 7, Issue 5, 2012, Pages 871-882

  Bionda, Nina ^a,b   Stawikowski, Maciej ^a   Stawikowska, Roma ^a   Cudic, Maré ^a   López Vallejo, Fabian ^a   Treitl, Daniela ^b   Medina Franco, José ^a   Cudic, Predrag ^a  

^a TORREY PINES INSTITUTE FOR MOLECULAR STUDIES   (United States)

^b FLORIDA ATLANTIC UNIVERSITY   (United States)

Author keywords

Antibiotics; Drug resistance; Ester to amide substitution; Peptides; Structure activity relationships

Indexed keywords

ANTIINFECTIVE AGENT; FUSARICIDIN A; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; CYTOTOXICITY; DRUG EFFICACY; DRUG STABILITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; HYDROPHOBICITY; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; SOLID PHASE SYNTHESIS; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS EPIDERMIDIS; STREPTOCOCCUS PYOGENES; STRUCTURE ACTIVITY RELATION;

AMIDES; ANTI-BACTERIAL AGENTS; BACTERIA; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CIRCULAR DICHROISM; DEPSIPEPTIDES; DRUG DESIGN; DRUG RESISTANCE, BACTERIAL; DRUG STABILITY; HUMANS; MICROBIAL SENSITIVITY TESTS; MOLECULAR CONFORMATION; MOLECULAR STRUCTURE; PEPTIDES, CYCLIC;

EID: 84860341300     PISSN: 18607179     EISSN: 18607187     Source Type: Journal    
DOI: 10.1002/cmdc.201200016     Document Type: Article

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