Amide-to-ester substitution in coiled coils: The effect of removing hydrogen bonds on protein structure

Angewandte Chemie - International Edition

Volumn 46, Issue 41, 2007, Pages 7766-7769

  Scheike, Jessica A ^a   Baldauf, Carsten ^b   Spengler, Jan ^c   Albericio, Fernando ^c   Pisabarro, M Teresa ^b   Koksch, Beate ^a  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

^b DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^c UNIVERSITY OF BARCELONA   (Spain)

Author keywords

Depsipeptides; Hydrogen bonds; Molecular dynamics; Protein folding; Superhelices

Indexed keywords

AMIDES; CHEMICAL STABILITY; COMPUTER SIMULATION; ESTERS; HYDROGEN BONDS; HYDROPHOBICITY; MOLECULAR DYNAMICS; PROTEIN FOLDING;

DEPSIPEPTIDES; HYDROPHOBIC INTERACTIONS; PROTEIN STRUCTURES; SOLVENT EXPOSED REGIONS; SUPERHELICES;

PEPTIDES;

AMIDE; ESTER; GUANIDINE; PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; CHEMISTRY; CIRCULAR DICHROISM; COMPUTER SIMULATION; HYDROGEN BOND; PROTEIN DENATURATION; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; THERMODYNAMICS;

AMIDES; AMINO ACID SEQUENCE; CIRCULAR DICHROISM; COMPUTER SIMULATION; ESTERS; GUANIDINE; HYDROGEN BONDING; PROTEIN DENATURATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; PROTEINS; THERMODYNAMICS;

EID: 35349013121     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200702218     Document Type: Article

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