A Sonic hedgehog (Shh) response deficit in trisomic cells may be a common denominator for multiple features of Down syndrome

Progress in Brain Research

Volumn 197, Issue , 2012, Pages 223-236

  Currier, Duane G ^a   Polk, Renita C ^a   Reeves, Roger H ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Brain development; Cerebellum; Common denominators of Down syndrome; Down syndrome; Neural crest; SHH signaling

Indexed keywords

SONIC HEDGEHOG PROTEIN;

ARTICLE; BRAIN DEVELOPMENT; CRANIOFACIAL DEVELOPMENT; DOWN SYNDROME; GENE; GENE OVEREXPRESSION; GENETIC TRANSCRIPTION; HEART DEVELOPMENT; HSA21 GENE; HUMAN; HYPOTHESIS; MUTANT; NERVOUS SYSTEM; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TRISOMY;

EID: 84860337278     PISSN: 00796123     EISSN: 18757855     Source Type: Book Series    
DOI: 10.1016/B978-0-444-54299-1.00011-X     Document Type: Chapter

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