메뉴 건너뛰기




Volumn 12, Issue 2, 2012, Pages 129-137

The non-structural proteins of RSV: Targeting interferon antagonists for vaccine development

Author keywords

Interferon; Live attenuated vaccines; Mutagenesis; Nonstructural proteins; Recombinant virus; Viral replication

Indexed keywords

INTERFERON; NONSTRUCTURAL PROTEIN 1; NONSTRUCTURAL PROTEIN 2; RESPIRATORY SYNCYTIAL VIRUS VACCINE; VACCINE; VIRUS PROTEIN;

EID: 84860271918     PISSN: 18715265     EISSN: 18755852     Source Type: Journal    
DOI: 10.2174/187152612800100170     Document Type: Review
Times cited : (7)

References (101)
  • 1
    • 0022589125 scopus 로고
    • Risk of primary infection and reinfection with respiratory syncytial virus
    • Glezen, W. P.; Taber, L. H.; Frank, A. L.; Kasel, J. A. Risk of primary infection and reinfection with respiratory syncytial virus. Am. J. Dis. Child, 1986, 140(6), 543-546.
    • (1986) Am. J. Dis. Child, , vol.140 , Issue.6 , pp. 543-546
    • Glezen, W.P.1    Taber, L.H.2    Frank, A.L.3    Kasel, J.A.4
  • 2
    • 0025275762 scopus 로고
    • Association between respiratory syncytial virus outbreaks and lower respiratory tract deaths of infants and young children
    • Anderson, L. J.; Parker, R. A.; Strikas, R. L. Association between respiratory syncytial virus outbreaks and lower respiratory tract deaths of infants and young children. J. Infect. Dis., 1990, 161(4), 640-646.
    • (1990) J. Infect. Dis. , vol.161 , Issue.4 , pp. 640-646
    • Anderson, L.J.1    Parker, R.A.2    Strikas, R.L.3
  • 3
    • 2142657849 scopus 로고    scopus 로고
    • Economic impact of respiratory syncytial virus-related illness in the US: An analysis of national databases
    • Paramore, L. C.; Ciuryla, V.; Ciesla, G.; Liu, L. Economic impact of respiratory syncytial virus-related illness in the US: an analysis of national databases. Pharmacoeconomics, 2004, 22(5), 275-284.
    • (2004) Pharmacoeconomics, , vol.22 , Issue.5 , pp. 275-284
    • Paramore, L.C.1    Ciuryla, V.2    Ciesla, G.3    Liu, L.4
  • 4
    • 0032696770 scopus 로고    scopus 로고
    • Bronchiolitis-associated hospitalizations among US children, 1980-1996
    • Shay, D. K.; Holman, R. C.; Newman, R. D.; Liu, L. L.; Stout, J. W.; Anderson, L. J. Bronchiolitis-associated hospitalizations among US children, 1980-1996. JAMA, 1999, 282(15), 1440-1446.
    • (1999) JAMA, , vol.282 , Issue.15 , pp. 1440-1446
    • Shay, D.K.1    Holman, R.C.2    Newman, R.D.3    Liu, L.L.4    Stout, J.W.5    Anderson, L.J.6
  • 5
    • 0035168864 scopus 로고    scopus 로고
    • Bronchiolitis-associated mortality and estimates of respiratory syncytial virus-associated deaths among US children, 1979-1997
    • Shay, D. K.; Holman, R. C.; Roosevelt, G. E.; Clarke, M. J.; Anderson, L. J. Bronchiolitis-associated mortality and estimates of respiratory syncytial virus-associated deaths among US children, 1979-1997. J. Infect. Dis., 2001, 183(1), 16-22.
    • (2001) J. Infect. Dis. , vol.183 , Issue.1 , pp. 16-22
    • Shay, D.K.1    Holman, R.C.2    Roosevelt, G.E.3    Clarke, M.J.4    Anderson, L.J.5
  • 6
    • 0033843988 scopus 로고    scopus 로고
    • Respiratory syncytial virus in patients with congenital heart disease: A contemporary look at epidemiology and success of preoperative screening
    • Altman, C. A.; Englund, J. A.; Demmler, G.; Drescher, K. L.; Alexander, M. A.; Watrin, C.; Feltes, T. F. Respiratory syncytial virus in patients with congenital heart disease: a contemporary look at epidemiology and success of preoperative screening. Pediatr. Cardiol., 2000, 21(5), 433-438.
    • (2000) Pediatr. Cardiol. , vol.21 , Issue.5 , pp. 433-438
    • Altman, C.A.1    Englund, J.A.2    Demmler, G.3    Drescher, K.L.4    Alexander, M.A.5    Watrin, C.6    Feltes, T.F.7
  • 7
    • 0031772653 scopus 로고    scopus 로고
    • Ventricular arrhythymia associated with respiratory syncytial viral infection
    • Huang, M.; Bigos, D.; Levine, M. Ventricular arrhythymia associated with respiratory syncytial viral infection. Pediatr. Cardiol., 1998, 19(6), 498-500.
    • (1998) Pediatr. Cardiol. , vol.19 , Issue.6 , pp. 498-500
    • Huang, M.1    Bigos, D.2    Levine, M.3
  • 8
    • 16644380035 scopus 로고    scopus 로고
    • Economic analysis of palivizumab in infants with congenital heart disease
    • Yount, L. E.; Mahle, W. T. Economic analysis of palivizumab in infants with congenital heart disease. Pediatrics, 2004, 114(6), 1606-11.
    • (2004) Pediatrics, , vol.114 , Issue.6 , pp. 1606-1611
    • Yount, L.E.1    Mahle, W.T.2
  • 9
    • 0035723393 scopus 로고    scopus 로고
    • Risk factors for severe respiratory syncytial virus-associated lower respiratory tract infection in children
    • Kaneko, M.; Watanabe, J.; Ueno, E.; Hida, M.; Sone, T. Risk factors for severe respiratory syncytial virus-associated lower respiratory tract infection in children. Pediatr. Int., 2001, 43(5), 489-492.
    • (2001) Pediatr. Int. , vol.43 , Issue.5 , pp. 489-492
    • Kaneko, M.1    Watanabe, J.2    Ueno, E.3    Hida, M.4    Sone, T.5
  • 10
    • 0000768105 scopus 로고    scopus 로고
    • Respiratory syncytial virus
    • In, Fourth ed.; Knipe, D. M.; Howley, P. M. Eds. Lippincott, Williams and Wilkins: Philadelphia
    • Collins, P. L.; Chanock, R. M.; Murphy, B. R. Respiratory syncytial virus. In: Fields Virology, Fourth ed.; Knipe, D. M.; Howley, P. M. Eds. Lippincott, Williams and Wilkins: Philadelphia, 2001; pp 1443-1485.
    • (2001) Fields Virology , pp. 1443-1485
    • Collins, P.L.1    Chanock, R.M.2    Murphy, B.R.3
  • 11
    • 0000089226 scopus 로고    scopus 로고
    • Respiratory syncytial virus and metapneumoviruses
    • thed.; Knipe, D. M.; Howley, P. M.; Griffin, D. E.; Lamb, R. A.; Martin, M. A.; Roizman, B. Straus, S. E. Eds., Lippincott Williams & Wilkins
    • thed.; Knipe, D. M.; Howley, P. M.; Griffin, D. E.; Lamb, R. A.; Martin, M. A.; Roizman, B.; Straus, S. E. Eds., Lippincott Williams & Wilkins: 2007.
    • (2007) Field's Virology
    • Collins, P.L.1    Crowe, J.E.J.2
  • 14
    • 12344307260 scopus 로고    scopus 로고
    • Acute lower respiratory tract infections and respiratory syncytial virus in infants in Guinea-Bissau: A beneficial effect of BCG vaccination for girls community based case-control study
    • Stensballe, L. G.; Nante, E.; Jensen, I. P.; Kofoed, P. E.; Poulsen, A.; Jensen, H.; Newport, M.; Marchant, A.; Aaby, P. Acute lower respiratory tract infections and respiratory syncytial virus in infants in Guinea-Bissau: a beneficial effect of BCG vaccination for girls community based case-control study. Vaccine, 2005, 23(10), 1251-1257.
    • (2005) Vaccine, , vol.23 , Issue.10 , pp. 1251-1257
    • Stensballe, L.G.1    Nante, E.2    Jensen, I.P.3    Kofoed, P.E.4    Poulsen, A.5    Jensen, H.6    Newport, M.7    Marchant, A.8    Aaby, P.9
  • 16
    • 67649400909 scopus 로고    scopus 로고
    • Mucosal immunosenescence: New developments and vaccines to control infectious diseases
    • Fujihashi, K.; Kiyono, H. Mucosal immunosenescence: new developments and vaccines to control infectious diseases. Trends Immunol., 2009, 30(7), 334-343.
    • (2009) Trends Immunol. , vol.30 , Issue.7 , pp. 334-343
    • Fujihashi, K.1    Kiyono, H.2
  • 18
    • 74049116256 scopus 로고    scopus 로고
    • Effects of aging on the adaptive immune response to respiratory virus infections
    • Fulton, R. B.; Varga, S. M. Effects of aging on the adaptive immune response to respiratory virus infections. Aging Health, 2009, 5(6), 775.
    • (2009) Aging Health, , vol.5 , Issue.6 , pp. 775
    • Fulton, R.B.1    Varga, S.M.2
  • 20
    • 61349097791 scopus 로고    scopus 로고
    • B-cell responses to vaccination at the extremes of age
    • Siegrist, C. A.; Aspinall, R. B-cell responses to vaccination at the extremes of age. Nat. Rev. Immunol., 2009, 9(3), 185-194.
    • (2009) Nat. Rev. Immunol. , vol.9 , Issue.3 , pp. 185-194
    • Siegrist, C.A.1    Aspinall, R.2
  • 21
    • 34250866280 scopus 로고    scopus 로고
    • The challenges of vaccine responses in early life: Selected examples
    • Siegrist, C. A. The challenges of vaccine responses in early life: selected examples. J. Comp. Pathol., 2007, 137 (Suppl 1), S4-9.
    • (2007) J. Comp. Pathol. , vol.137 , Issue.SUPPL. 1
    • Siegrist, C.A.1
  • 22
    • 34250883967 scopus 로고    scopus 로고
    • Immune responsiveness in the neonatal period
    • Morein, B.; Blomqvist, G.; Hu, K. Immune responsiveness in the neonatal period. J. Comp. Pathol., 2007, 137 (Suppl 1), S27-31.
    • (2007) J. Comp. Pathol. , vol.137 , Issue.SUPPL. 1
    • Morein, B.1    Blomqvist, G.2    Hu, K.3
  • 23
    • 70450225059 scopus 로고    scopus 로고
    • The human neonatal B cell response to respiratory syncytial virus uses a biased antibody variable gene repertoire that lacks somatic mutations
    • Williams, J. V.; Weitkamp, J. H.; Blum, D. L.; LaFleur, B. J.; Crowe, J. E. Jr. The human neonatal B cell response to respiratory syncytial virus uses a biased antibody variable gene repertoire that lacks somatic mutations. Mol. Immunol., 2009, 47(2-3), 407-414.
    • (2009) Mol. Immunol. , vol.47 , Issue.2-3 , pp. 407-414
    • Williams, J.V.1    Weitkamp, J.H.2    Blum, D.L.3    LaFleur, B.J.4    Crowe Jr., J.E.5
  • 24
    • 0014493282 scopus 로고
    • An epidemiologic study of altered clinical reactivity to respiratory syncytial (RS) virus infection in children previously vaccinated with an inactivated RS virus vaccine
    • Kapikian, A. Z.; Mitchell, R. H.; Chanock, R. M.; Shvedoff, R. A.; Stewart, C. E. An epidemiologic study of altered clinical reactivity to respiratory syncytial (RS) virus infection in children previously vaccinated with an inactivated RS virus vaccine. Am. J. Epidemiol., 1969, 89(4), 405-421.
    • (1969) Am. J. Epidemiol. , vol.89 , Issue.4 , pp. 405-421
    • Kapikian, A.Z.1    Mitchell, R.H.2    Chanock, R.M.3    Shvedoff, R.A.4    Stewart, C.E.5
  • 25
    • 0014495251 scopus 로고
    • Respiratory syncytial virus disease in infants despite prior administration of antigenic inactivated vaccine
    • Kim, H. W.; Canchola, J. G.; Brandt, C. D.; Pyles, G.; Chanock, R. M.; Jensen, K.; Parrott, R. H. Respiratory syncytial virus disease in infants despite prior administration of antigenic inactivated vaccine. Am. J. Epidemiol., 1969, 89(4), 422-434.
    • (1969) Am. J. Epidemiol. , vol.89 , Issue.4 , pp. 422-434
    • Kim, H.W.1    Canchola, J.G.2    Brandt, C.D.3    Pyles, G.4    Chanock, R.M.5    Jensen, K.6    Parrott, R.H.7
  • 26
    • 0015787791 scopus 로고
    • Safety and antigenicity of temperature sensitive (TS) mutant respiratory syncytial virus (RSV) in infants and children
    • Kim, H. W.; Arrobio, J. O.; Brandt, C. D.; Wright, P.; Hodes, D.; Chanock, R. M.; Parrott, R. H. Safety and antigenicity of temperature sensitive (TS) mutant respiratory syncytial virus (RSV) in infants and children. Pediatrics, 1973, 52(1), 56-63.
    • (1973) Pediatrics, , vol.52 , Issue.1 , pp. 56-63
    • Kim, H.W.1    Arrobio, J.O.2    Brandt, C.D.3    Wright, P.4    Hodes, D.5    Chanock, R.M.6    Parrott, R.H.7
  • 27
    • 35348828518 scopus 로고    scopus 로고
    • Understanding respiratory syncytial virus (RSV) vaccine-enhanced disease
    • Castilow, E. M.; Olson, M. R.; Varga, S. M. Understanding respiratory syncytial virus (RSV) vaccine-enhanced disease. Immunol. Res., 2007, 39(1-3), 225-239.
    • (2007) Immunol. Res. , vol.39 , Issue.1-3 , pp. 225-239
    • Castilow, E.M.1    Olson, M.R.2    Varga, S.M.3
  • 28
    • 9644301013 scopus 로고    scopus 로고
    • Involvement of antibody, complement and cellular immunity in the pathogenesis of enhanced respiratory syncytial virus disease
    • Delgado, M. F.; Polack, F. P. Involvement of antibody, complement and cellular immunity in the pathogenesis of enhanced respiratory syncytial virus disease. Expert Rev. Vaccines, 2004, 3(6), 693-700.
    • (2004) Expert Rev. Vaccines, , vol.3 , Issue.6 , pp. 693-700
    • Delgado, M.F.1    Polack, F.P.2
  • 31
    • 84886607831 scopus 로고
    • Evaluation of a live, attenuated respiratory syncytial virus vaccine in infants
    • Wright, P. F.; Shinozaki, T.; Fleet, W.; Sell, S. H.; Thompson, J.; Karzon, D. T. Evaluation of a live, attenuated respiratory syncytial virus vaccine in infants. J. Pediatr., 1976, 88(6), 931-936.
    • (1976) J. Pediatr. , vol.88 , Issue.6 , pp. 931-936
    • Wright, P.F.1    Shinozaki, T.2    Fleet, W.3    Sell, S.H.4    Thompson, J.5    Karzon, D.T.6
  • 32
    • 0031457568 scopus 로고    scopus 로고
    • Respiratory syncytial virus (RSV) SH and G proteins are not essential for viral replication in vitro: Clinical evaluation and molecular characterization of a cold-passaged, attenuated RSV subgroup B mutant
    • Karron, R. A.; Buonagurio, D. A.; Georgiu, A. F.; Whitehead, S. S.; Adamus, J. E.; Clements-Mann, M. L.; Harris, D. O.; Randolph, V. B.; Udem, S. A.; Murphy, B. R.; Sidhu, M. S. Respiratory syncytial virus (RSV) SH and G proteins are not essential for viral replication in vitro: clinical evaluation and molecular characterization of a cold-passaged, attenuated RSV subgroup B mutant. Proc. Natl. Acad. Sci. USA, 1997, 94(25), 13961-1396.
    • (1997) Proc. Natl. Acad. Sci. USA, , vol.94 , Issue.25 , pp. 11396-13961
    • Karron, R.A.1    Buonagurio, D.A.2    Georgiu, A.F.3    Whitehead, S.S.4    Adamus, J.E.5    Clements-Mann, M.L.6    Harris, D.O.7    Randolph, V.B.8    Udem, S.A.9    Murphy, B.R.10    Sidhu, M.S.11
  • 34
    • 0030657620 scopus 로고    scopus 로고
    • Evaluation of two live, cold-passaged, temperature-sensitive respiratory syncytial virus vaccines in chimpanzees and in human adults, infants, and children
    • Karron, R. A.; Wright, P. F.; Crowe, J. E., Jr.; Clements-Mann, M. L.; Thompson, J.; Makhene, M.; Casey, R.; Murphy, B. R. Evaluation of two live, cold-passaged, temperature-sensitive respiratory syncytial virus vaccines in chimpanzees and in human adults, infants, and children. J. Infect. Dis., 1997, 176(6), 1428-1436.
    • (1997) J. Infect. Dis. , vol.176 , Issue.6 , pp. 1428-1436
    • Karron, R.A.1    Wright, P.F.2    Crowe Jr., J.E.3    Clements-Mann, M.L.4    Thompson, J.5    Makhene, M.6    Casey, R.7    Murphy, B.R.8
  • 35
    • 0022408938 scopus 로고
    • Comparison of long-term systemic and secretory antibody responses in children given live, attenuated, or inactivated influenza A vaccine
    • Johnson, P. R. Jr.; Feldman, S.; Thompson, J. M.; Mahoney, J. D.; Wright, P. F. Comparison of long-term systemic and secretory antibody responses in children given live, attenuated, or inactivated influenza A vaccine. J. Med. Virol., 1985, 17(4), 325-335.
    • (1985) J. Med. Virol. , vol.17 , Issue.4 , pp. 325-335
    • Johnson Jr., P.R.1    Feldman, S.2    Thompson, J.M.3    Mahoney, J.D.4    Wright, P.F.5
  • 36
    • 0022473254 scopus 로고
    • Immunity to influenza A virus infection in young children: A comparison of natural infection, live cold-adapted vaccine, and inactivated vaccine
    • Johnson, P. R.; Feldman, S.; Thompson, J. M.; Mahoney, J. D.; Wright, P. F. Immunity to influenza A virus infection in young children: a comparison of natural infection, live cold-adapted vaccine, and inactivated vaccine. J. Infect. Dis., 1986, 154(1), 121-127.
    • (1986) J. Infect. Dis. , vol.154 , Issue.1 , pp. 121-127
    • Johnson, P.R.1    Feldman, S.2    Thompson, J.M.3    Mahoney, J.D.4    Wright, P.F.5
  • 37
    • 0015096514 scopus 로고
    • Experimental respiratory syncytial virus infection of adults. Possible mechanisms of resistance to infection and illness
    • Mills, J. t.; Van Kirk, J. E.; Wright, P. F.; Chanock, R. M. Experimental respiratory syncytial virus infection of adults. Possible mechanisms of resistance to infection and illness. J. Immunol., 1971, 107(1), 123-130.
    • (1971) J. Immunol. , vol.107 , Issue.1 , pp. 123-130
    • Mills, J.t.1    van Kirk, J.E.2    Wright, P.F.3    Chanock, R.M.4
  • 38
    • 0842327819 scopus 로고    scopus 로고
    • The future of respiratory syncytial virus vaccine development
    • Polack, F. P.; Karron, R. A. The future of respiratory syncytial virus vaccine development. Pediatr. Infect. Dis. J., 2004, 23(1 Suppl), S65-73.
    • (2004) Pediatr. Infect. Dis. J. , vol.23 , Issue.SUPPL. 1
    • Polack, F.P.1    Karron, R.A.2
  • 39
    • 0032623340 scopus 로고    scopus 로고
    • Rational design of live-attenuated recombinant vaccine virus for human respiratory syncytial virus by reverse genetics
    • Collins, P. L.; Whitehead, S. S.; Bukreyev, A.; Fearns, R.; Teng, M. N.; Juhasz, K.; Chanock, R. M.; Murphy, B. R. Rational design of live-attenuated recombinant vaccine virus for human respiratory syncytial virus by reverse genetics. Adv. Virus Res., 1999, 54, 423-451.
    • (1999) Adv. Virus Res. , vol.54 , pp. 423-451
    • Collins, P.L.1    Whitehead, S.S.2    Bukreyev, A.3    Fearns, R.4    Teng, M.N.5    Juhasz, K.6    Chanock, R.M.7    Murphy, B.R.8
  • 40
    • 0027340418 scopus 로고
    • Immunogenicity and pathogenicity of a triple temperature-sensitive modified respiratory syncytial virus in adult volunteers
    • Pringle, C. R.; Filipiuk, A. H.; Robinson, B. S.; Watt, P. J.; Higgins, P.; Tyrrell, D. A. Immunogenicity and pathogenicity of a triple temperature-sensitive modified respiratory syncytial virus in adult volunteers. Vaccine, 1993, 11(4), 473-478.
    • (1993) Vaccine, , vol.11 , Issue.4 , pp. 473-478
    • Pringle, C.R.1    Filipiuk, A.H.2    Robinson, B.S.3    Watt, P.J.4    Higgins, P.5    Tyrrell, D.A.6
  • 41
    • 0015149518 scopus 로고
    • Evaluation of a temperature-sensitive mutant of respiratory syncytial virus in adults
    • Wright, P. F.; Mills, J.; Chanock, R. M. Evaluation of a temperature-sensitive mutant of respiratory syncytial virus in adults. J. Infect. Dis., 1971, 124(5), 505-511.
    • (1971) J. Infect. Dis. , vol.124 , Issue.5 , pp. 505-511
    • Wright, P.F.1    Mills, J.2    Chanock, R.M.3
  • 42
    • 0019974042 scopus 로고
    • Administration of a highly attenuated, live respiratory syncytial virus vaccine to adults and children
    • Wright, P. F.; Belshe, R. B.; Kim, H. W.; Van Voris, L. P.; Chanock, R. M. Administration of a highly attenuated, live respiratory syncytial virus vaccine to adults and children. Infect. Immun., 1982, 37(1), 397-400.
    • (1982) Infect. Immun. , vol.37 , Issue.1 , pp. 397-400
    • Wright, P.F.1    Belshe, R.B.2    Kim, H.W.3    van Voris, L.P.4    Chanock, R.M.5
  • 43
    • 34748850172 scopus 로고    scopus 로고
    • The absence of enhanced disease with wild type respiratory syncytial virus infection occurring after receipt of live, attenuated, respiratory syncytial virus vaccines
    • Wright, P. F.; Karron, R. A.; Belshe, R. B.; Shi, J. R.; Randolph, V. B.; Collins, P. L.; O'Shea, A. F.; Gruber, W. C.; Murphy, B. R. The absence of enhanced disease with wild type respiratory syncytial virus infection occurring after receipt of live, attenuated, respiratory syncytial virus vaccines. Vaccine, 2007, 25(42), 7372-7378.
    • (2007) Vaccine, , vol.25 , Issue.42 , pp. 7372-7378
    • Wright, P.F.1    Karron, R.A.2    Belshe, R.B.3    Shi, J.R.4    Randolph, V.B.5    Collins, P.L.6    O'Shea, A.F.7    Gruber, W.C.8    Murphy, B.R.9
  • 44
    • 0032932708 scopus 로고    scopus 로고
    • Addition of a missense mutation present in the L gene of respiratory syncytial virus (RSV) cpts530/1030 to RSV vaccine candidate cpts248/404 increases its attenuation and temperature sensitivity
    • Whitehead, S. S.; Firestone, C. Y.; Karron, R. A.; Crowe, J. E. Jr.; Elkins, W. R.; Collins, P. L.; Murphy, B. R. Addition of a missense mutation present in the L gene of respiratory syncytial virus (RSV) cpts530/1030 to RSV vaccine candidate cpts248/404 increases its attenuation and temperature sensitivity. J. Virol., 1999, 73(2), 871-877.
    • (1999) J. Virol. , vol.73 , Issue.2 , pp. 871-877
    • Whitehead, S.S.1    Firestone, C.Y.2    Karron, R.A.3    Crowe Jr., J.E.4    Elkins, W.R.5    Collins, P.L.6    Murphy, B.R.7
  • 45
    • 70349231214 scopus 로고    scopus 로고
    • The regulation of type I interferon production by paramyxoviruses
    • Goodbourn, S.; Randall, R. E. The regulation of type I interferon production by paramyxoviruses. J. Interferon. Cytokine Res., 2009, 29(9), 539-547.
    • (2009) J. Interferon. Cytokine Res. , vol.29 , Issue.9 , pp. 539-547
    • Goodbourn, S.1    Randall, R.E.2
  • 48
    • 33744539798 scopus 로고    scopus 로고
    • Toll-like receptors and RNA helicases: Two parallel ways to trigger antiviral responses
    • Meylan, E.; Tschopp, J. Toll-like receptors and RNA helicases: two parallel ways to trigger antiviral responses. Mol. Cell, 2006, 22(5), 561-569.
    • (2006) Mol. Cell, , vol.22 , Issue.5 , pp. 561-569
    • Meylan, E.1    Tschopp, J.2
  • 51
    • 0141923690 scopus 로고    scopus 로고
    • Toll/IL-1 receptor domain-containing adaptor inducing IFN-beta (TRIF) associates with TNF receptor-associated factor 6 and TANK-binding kinase 1, and activates two distinct transcription factors, NF-kappa B and IFN-regulatory factor-3, in the Toll-like receptor signaling
    • Sato, S.; Sugiyama, M.; Yamamoto, M.; Watanabe, Y.; Kawai, T.; Takeda, K.; Akira, S. Toll/IL-1 receptor domain-containing adaptor inducing IFN-beta (TRIF) associates with TNF receptor-associated factor 6 and TANK-binding kinase 1, and activates two distinct transcription factors, NF-kappa B and IFN-regulatory factor-3, in the Toll-like receptor signaling. J. Immunol., 2003, 171(8), 4304-4310.
    • (2003) J. Immunol. , vol.171 , Issue.8 , pp. 4304-4310
    • Sato, S.1    Sugiyama, M.2    Yamamoto, M.3    Watanabe, Y.4    Kawai, T.5    Takeda, K.6    Akira, S.7
  • 53
    • 77951708374 scopus 로고    scopus 로고
    • Reconstitution of the RIG-I pathway reveals a signaling role of unanchored polyubiquitin chains in innate immunity
    • Zeng, W.; Sun, L.; Jiang, X.; Chen, X.; Hou, F.; Adhikari, A.; Xu, M.; Chen, Z. J. Reconstitution of the RIG-I pathway reveals a signaling role of unanchored polyubiquitin chains in innate immunity. Cell, 2010, 141(2), 315-330.
    • (2010) Cell, , vol.141 , Issue.2 , pp. 315-330
    • Zeng, W.1    Sun, L.2    Jiang, X.3    Chen, X.4    Hou, F.5    Adhikari, A.6    Xu, M.7    Chen, Z.J.8
  • 54
    • 1342284289 scopus 로고    scopus 로고
    • Convergence of the NF-kappaB and interferon signaling pathways in the regulation of antiviral defense and apoptosis
    • Hiscott, J.; Grandvaux, N.; Sharma, S.; Tenoever, B. R.; Servant, M. J.; Lin, R. Convergence of the NF-kappaB and interferon signaling pathways in the regulation of antiviral defense and apoptosis. Ann. N. Y. Acad. Sci., 2003, 1010, 237-248.
    • (2003) Ann. N. Y. Acad. Sci. , vol.1010 , pp. 237-248
    • Hiscott, J.1    Grandvaux, N.2    Sharma, S.3    Tenoever, B.R.4    Servant, M.J.5    Lin, R.6
  • 55
    • 33846554134 scopus 로고    scopus 로고
    • Retinoic acid-inducible gene I mediates early antiviral response and Toll-like receptor 3 expression in respiratory syncytial virus-infected airway epithelial cells
    • Liu, P.; Jamaluddin, M.; Li, K.; Garofalo, R. P.; Casola, A.; Brasier, A. R. Retinoic acid-inducible gene I mediates early antiviral response and Toll-like receptor 3 expression in respiratory syncytial virus-infected airway epithelial cells. J. Virol., 2007, 81(3), 1401-1411.
    • (2007) J. Virol. , vol.81 , Issue.3 , pp. 1401-1411
    • Liu, P.1    Jamaluddin, M.2    Li, K.3    Garofalo, R.P.4    Casola, A.5    Brasier, A.R.6
  • 56
    • 0025359420 scopus 로고
    • The efficacy of intranasal interferon alpha-2a in respiratory syncytial virus infection in volunteers
    • Higgins, P. G.; Barrow, G. I.; Tyrrell, D. A.; Isaacs, D.; Gauci, C. L. The efficacy of intranasal interferon alpha-2a in respiratory syncytial virus infection in volunteers. Antiviral Res., 1990, 14(1), 3-10.
    • (1990) Antiviral Res. , vol.14 , Issue.1 , pp. 3-10
    • Higgins, P.G.1    Barrow, G.I.2    Tyrrell, D.A.3    Isaacs, D.4    Gauci, C.L.5
  • 57
    • 0034608232 scopus 로고    scopus 로고
    • Role of type I IFNs in the in vitro attenuation of live, temperature-sensitive vaccine strains of human respiratory syncytial virus
    • Loveys, D. A.; Kulkarni, S.; Atreya, P. L. Role of type I IFNs in the in vitro attenuation of live, temperature-sensitive vaccine strains of human respiratory syncytial virus. Virology, 2000, 271(2), 390-400.
    • (2000) Virology, , vol.271 , Issue.2 , pp. 390-400
    • Loveys, D.A.1    Kulkarni, S.2    Atreya, P.L.3
  • 58
    • 0344500647 scopus 로고    scopus 로고
    • Respiratory syncytial virus strain A2 is resistant to the antiviral effects of type I interferons and human MxA
    • Atreya, P. L.; Kulkarni, S. Respiratory syncytial virus strain A2 is resistant to the antiviral effects of type I interferons and human MxA. Virology, 1999, 261(2), 227-241.
    • (1999) Virology, , vol.261 , Issue.2 , pp. 227-241
    • Atreya, P.L.1    Kulkarni, S.2
  • 59
    • 0027214362 scopus 로고
    • Alpha-2A-interferon for treatment of bronchiolitis caused by respiratory syncytial virus
    • Chipps, B. E.; Sullivan, W. F.; Portnoy, J. M. Alpha-2A-interferon for treatment of bronchiolitis caused by respiratory syncytial virus. Pediatr. Infect. Dis. J., 1993, 12(8), 653-658.
    • (1993) Pediatr. Infect. Dis. J. , vol.12 , Issue.8 , pp. 653-658
    • Chipps, B.E.1    Sullivan, W.F.2    Portnoy, J.M.3
  • 60
    • 0037204953 scopus 로고    scopus 로고
    • A road map for those who don't know JAK-STAT
    • Aaronson, D. S.; Horvath, C. M. A road map for those who don't know JAK-STAT. Science, 2002, 296(5573), 1653-1655.
    • (2002) Science, , vol.296 , Issue.5573 , pp. 1653-1655
    • Aaronson, D.S.1    Horvath, C.M.2
  • 61
    • 0034948808 scopus 로고    scopus 로고
    • The virus battles: IFN induction of the antiviral state and mechanisms of viral evasion
    • Levy, D. E.; Garcia-Sastre, A. The virus battles: IFN induction of the antiviral state and mechanisms of viral evasion. Cytokine Growth Factor Rev., 2001, 12(2-3), 143-156.
    • (2001) Cytokine Growth Factor Rev. , vol.12 , Issue.2-3 , pp. 143-156
    • Levy, D.E.1    Garcia-Sastre, A.2
  • 62
    • 0036668242 scopus 로고    scopus 로고
    • Links between innate and adaptive immunity via type I interferon
    • Le Bon, A.; Tough, D. F. Links between innate and adaptive immunity via type I interferon. Curr. Opin. Immunol., 2002, 14(4), 432-436.
    • (2002) Curr. Opin. Immunol. , vol.14 , Issue.4 , pp. 432-436
    • Le Bon, A.1    Tough, D.F.2
  • 64
    • 0032731094 scopus 로고    scopus 로고
    • The V protein of simian virus 5 inhibits interferon signalling by targeting STAT1 for proteasome-mediated degradation
    • Didcock, L.; Young, D. F.; Goodbourn, S.; Randall, R. E. The V protein of simian virus 5 inhibits interferon signalling by targeting STAT1 for proteasome-mediated degradation. J. Virol., 1999, 73(12), 9928-9933.
    • (1999) J. Virol. , vol.73 , Issue.12 , pp. 9928-9933
    • Didcock, L.1    Young, D.F.2    Goodbourn, S.3    Randall, R.E.4
  • 65
    • 70349239030 scopus 로고    scopus 로고
    • Paramyxovirus disruption of interferon signal transduction: STATus report
    • Ramachandran, A.; Horvath, C. M. Paramyxovirus disruption of interferon signal transduction: STATus report. J. Interferon. Cytokine Res., 2009, 29(9), 531-537.
    • (2009) J. Interferon. Cytokine Res. , vol.29 , Issue.9 , pp. 531-537
    • Ramachandran, A.1    Horvath, C.M.2
  • 68
    • 33846061693 scopus 로고    scopus 로고
    • Inhibition of retinoic acidinducible gene I-mediated induction of beta interferon by the NS1 protein of influenza A virus
    • Mibayashi, M.; Martinez-Sobrido, L.; Loo, Y. M.; Cardenas, W. B.; Gale, M. Jr.; Garcia-Sastre, A. Inhibition of retinoic acidinducible gene I-mediated induction of beta interferon by the NS1 protein of influenza A virus. J. Virol., 2007, 81(2), 514-524.
    • (2007) J. Virol. , vol.81 , Issue.2 , pp. 514-524
    • Mibayashi, M.1    Martinez-Sobrido, L.2    Loo, Y.M.3    Cardenas, W.B.4    Gale Jr., M.5    Garcia-Sastre, A.6
  • 70
    • 44949111358 scopus 로고    scopus 로고
    • Human metapneumovirus glycoprotein G inhibits innate immune responses
    • Bao, X.; Liu, T.; Shan, Y.; Li, K.; Garofalo, R. P.; Casola, A. Human metapneumovirus glycoprotein G inhibits innate immune responses. PLoS Pathog., 2008, 4(5), e1000077.
    • (2008) PLoS Pathog. , vol.4 , Issue.5
    • Bao, X.1    Liu, T.2    Shan, Y.3    Li, K.4    Garofalo, R.P.5    Casola, A.6
  • 71
    • 37349033589 scopus 로고    scopus 로고
    • Purification and characterization of recombinant human respiratory syncytial virus nonstructural protein NS1
    • Ling, Z.; Tran, K. C.; Arnold, J. J.; Teng, M. N. Purification and characterization of recombinant human respiratory syncytial virus nonstructural protein NS1. Protein Expr. Purif., 2008, 57(2), 261-70.
    • (2008) Protein Expr. Purif. , vol.57 , Issue.2 , pp. 261-270
    • Ling, Z.1    Tran, K.C.2    Arnold, J.J.3    Teng, M.N.4
  • 72
    • 0030220830 scopus 로고    scopus 로고
    • Expression and characterisation of the NS1 and NS2 proteins of respiratory syncytial virus
    • Evans, J. E.; Cane, P. A.; Pringle, C. R. Expression and characterisation of the NS1 and NS2 proteins of respiratory syncytial virus. Virus Res., 1996, 43(2), 155-161.
    • (1996) Virus Res. , vol.43 , Issue.2 , pp. 155-161
    • Evans, J.E.1    Cane, P.A.2    Pringle, C.R.3
  • 73
    • 0033911196 scopus 로고    scopus 로고
    • Domains of human respiratory syncytial virus P protein essential for homodimerization and for binding to N and NS1 protein
    • Hengst, U.; Kiefer, P. Domains of human respiratory syncytial virus P protein essential for homodimerization and for binding to N and NS1 protein. Virus Genes, 2000, 20(3), 221-225.
    • (2000) Virus Genes, , vol.20 , Issue.3 , pp. 221-225
    • Hengst, U.1    Kiefer, P.2
  • 74
    • 0031907721 scopus 로고    scopus 로고
    • The NS1 protein of human respiratory syncytial virus is a potent inhibitor of minigenome transcription and RNA replication
    • Atreya, P. L.; Peeples, M. E.; Collins, P. L. The NS1 protein of human respiratory syncytial virus is a potent inhibitor of minigenome transcription and RNA replication. J. Virol., 1998, 72(2), 1452-1461.
    • (1998) J. Virol. , vol.72 , Issue.2 , pp. 1452-1461
    • Atreya, P.L.1    Peeples, M.E.2    Collins, P.L.3
  • 75
    • 17444379364 scopus 로고    scopus 로고
    • Effects of nonstructural proteins NS1 and NS2 of human respiratory syncytial virus on interferon regulatory factor 3, NF-kappaB, and proinflammatory cytokines
    • Spann, K. M.; Tran, K. C.; Collins, P. L. Effects of nonstructural proteins NS1 and NS2 of human respiratory syncytial virus on interferon regulatory factor 3, NF-kappaB, and proinflammatory cytokines. J. Virol., 2005, 79(9), 5353-5362.
    • (2005) J. Virol. , vol.79 , Issue.9 , pp. 5353-5362
    • Spann, K.M.1    Tran, K.C.2    Collins, P.L.3
  • 76
    • 33846815515 scopus 로고    scopus 로고
    • Nonstructural proteins of respiratory syncytial virus suppress premature apoptosis by an NFkappaB-dependent, interferon-independent mechanism and facilitate virus growth
    • Bitko, V.; Shulyayeva, O.; Mazumder, B.; Musiyenko, A.; Ramaswamy, M.; Look, D. C.; Barik, S. Nonstructural proteins of respiratory syncytial virus suppress premature apoptosis by an NFkappaB-dependent, interferon-independent mechanism and facilitate virus growth. J. Virol., 2007, 81(4), 1786-1795.
    • (2007) J. Virol. , vol.81 , Issue.4 , pp. 1786-1795
    • Bitko, V.1    Shulyayeva, O.2    Mazumder, B.3    Musiyenko, A.4    Ramaswamy, M.5    Look, D.C.6    Barik, S.7
  • 77
    • 0036229487 scopus 로고    scopus 로고
    • Respiratory syncytial virus (RSV) nonstructural (NS) proteins as host range determinants: A chimeric bovine RSV with NS genes from human RSV is attenuated in interferon-competent bovine cells
    • Bossert, B.; Conzelmann, K. K. Respiratory syncytial virus (RSV) nonstructural (NS) proteins as host range determinants: a chimeric bovine RSV with NS genes from human RSV is attenuated in interferon-competent bovine cells. J. Virol., 2002, 76(9), 4287-4293.
    • (2002) J. Virol. , vol.76 , Issue.9 , pp. 4287-4293
    • Bossert, B.1    Conzelmann, K.K.2
  • 78
    • 0033866102 scopus 로고    scopus 로고
    • Bovine respiratory syncytial virus nonstructural proteins NS1 and NS2 cooperatively antagonize alpha/beta interferon-induced antiviral response
    • Schlender, J.; Bossert, B.; Buchholz, U.; Conzelmann, K. K. Bovine respiratory syncytial virus nonstructural proteins NS1 and NS2 cooperatively antagonize alpha/beta interferon-induced antiviral response. J. Virol., 2000, 74(18), 8234-8242.
    • (2000) J. Virol. , vol.74 , Issue.18 , pp. 8234-8242
    • Schlender, J.1    Bossert, B.2    Buchholz, U.3    Conzelmann, K.K.4
  • 79
    • 0043210589 scopus 로고    scopus 로고
    • Nonstructural proteins NS1 and NS2 of bovine respiratory syncytial virus block activation of interferon regulatory factor 3
    • Bossert, B.; Marozin, S.; Conzelmann, K. K. Nonstructural proteins NS1 and NS2 of bovine respiratory syncytial virus block activation of interferon regulatory factor 3. J. Virol., 2003, 77(16), 8661-8668.
    • (2003) J. Virol. , vol.77 , Issue.16 , pp. 8661-8668
    • Bossert, B.1    Marozin, S.2    Conzelmann, K.K.3
  • 80
    • 1842483896 scopus 로고    scopus 로고
    • Suppression of the induction of alpha, beta, and lambda interferons by the NS1 and NS2 proteins of human respiratory syncytial virus in human epithelial cells and macrophages [corrected]
    • Spann, K. M.; Tran, K. C.; Chi, B.; Rabin, R. L.; Collins, P. L. Suppression of the induction of alpha, beta, and lambda interferons by the NS1 and NS2 proteins of human respiratory syncytial virus in human epithelial cells and macrophages [corrected]. J. Virol., 2004, 78(8), 4363-4369.
    • (2004) J. Virol. , vol.78 , Issue.8 , pp. 4363-4369
    • Spann, K.M.1    Tran, K.C.2    Chi, B.3    Rabin, R.L.4    Collins, P.L.5
  • 81
    • 64049090424 scopus 로고    scopus 로고
    • Human respiratory syncytial virus nonstructural protein NS2 antagonizes the activation of beta interferon transcription by interacting with RIG-I
    • Ling, Z.; Tran, K. C.; Teng, M. N. Human respiratory syncytial virus nonstructural protein NS2 antagonizes the activation of beta interferon transcription by interacting with RIG-I. J. Virol., 2009, 83(8), 3734-3742.
    • (2009) J. Virol. , vol.83 , Issue.8 , pp. 3734-3742
    • Ling, Z.1    Tran, K.C.2    Teng, M.N.3
  • 82
    • 70349275249 scopus 로고    scopus 로고
    • Respiratory syncytial virus nonstructural proteins decrease levels of multiple members of the cellular interferon pathways
    • Swedan, S.; Musiyenko, A.; Barik, S. Respiratory syncytial virus nonstructural proteins decrease levels of multiple members of the cellular interferon pathways. J. Virol., 2009, 83(19), 9682-9693.
    • (2009) J. Virol. , vol.83 , Issue.19 , pp. 9682-9693
    • Swedan, S.1    Musiyenko, A.2    Barik, S.3
  • 83
    • 1642431694 scopus 로고    scopus 로고
    • Specific inhibition of type I interferon signal transduction by respiratory syncytial virus
    • Ramaswamy, M.; Shi, L.; Monick, M. M.; Hunninghake, G. W.; Look, D. C. Specific inhibition of type I interferon signal transduction by respiratory syncytial virus. Am. J. Respir. Cell Mol. Biol., 2004, 30(6), 893-900.
    • (2004) Am. J. Respir. Cell Mol. Biol. , vol.30 , Issue.6 , pp. 893-900
    • Ramaswamy, M.1    Shi, L.2    Monick, M.M.3    Hunninghake, G.W.4    Look, D.C.5
  • 84
    • 30044431891 scopus 로고    scopus 로고
    • Respiratory syncytial virus nonstructural protein 2 specifically inhibits type I interferon signal transduction
    • Ramaswamy, M.; Shi, L.; Varga, S. M.; Barik, S.; Behlke, M. A.; Look, D. C. Respiratory syncytial virus nonstructural protein 2 specifically inhibits type I interferon signal transduction. Virology, 2006, 344(2), 328-339.
    • (2006) Virology, , vol.344 , Issue.2 , pp. 328-339
    • Ramaswamy, M.1    Shi, L.2    Varga, S.M.3    Barik, S.4    Behlke, M.A.5    Look, D.C.6
  • 85
    • 20044387307 scopus 로고    scopus 로고
    • Respiratory syncytial virus nonstructural proteins NS1 and NS2 mediate inhibition of Stat2 expression and alpha/beta interferon responsiveness
    • Lo, M. S.; Brazas, R. M.; Holtzman, M. J. Respiratory syncytial virus nonstructural proteins NS1 and NS2 mediate inhibition of Stat2 expression and alpha/beta interferon responsiveness. J. Virol., 2005, 79(14), 9315-9319.
    • (2005) J. Virol. , vol.79 , Issue.14 , pp. 9315-9319
    • Lo, M.S.1    Brazas, R.M.2    Holtzman, M.J.3
  • 87
    • 55849145545 scopus 로고    scopus 로고
    • Respiratory syncytial virus (RSV) attachment and nonstructural proteins modify the type I interferon response associated with suppressor of cytokine signaling (SOCS) proteins and IFN-stimulated gene-15 (ISG15)
    • Moore, E. C.; Barber, J.; Tripp, R. A. Respiratory syncytial virus (RSV) attachment and nonstructural proteins modify the type I interferon response associated with suppressor of cytokine signaling (SOCS) proteins and IFN-stimulated gene-15 (ISG15). Virol. J., 2008, 5, 116.
    • (2008) Virol. J. , vol.5 , pp. 116
    • Moore, E.C.1    Barber, J.2    Tripp, R.A.3
  • 89
    • 0032889254 scopus 로고    scopus 로고
    • Altered growth characteristics of recombinant respiratory syncytial viruses which do not produce NS2 protein
    • Teng, M. N.; Collins, P. L. Altered growth characteristics of recombinant respiratory syncytial viruses which do not produce NS2 protein. J. Virol., 1999, 73(1), 466-473.
    • (1999) J. Virol. , vol.73 , Issue.1 , pp. 466-473
    • Teng, M.N.1    Collins, P.L.2
  • 90
    • 0034691566 scopus 로고    scopus 로고
    • Recombinant respiratory syncytial viruses with deletions in the NS1, NS2, SH, and M2-2 genes are attenuated in vitro and in vivo
    • Jin, H.; Zhou, H.; Cheng, X.; Tang, R.; Munoz, M.; Nguyen, N. Recombinant respiratory syncytial viruses with deletions in the NS1, NS2, SH, and M2-2 genes are attenuated in vitro and in vivo. Virology, 2000, 273(1), 210-218.
    • (2000) Virology, , vol.273 , Issue.1 , pp. 210-218
    • Jin, H.1    Zhou, H.2    Cheng, X.3    Tang, R.4    Munoz, M.5    Nguyen, N.6
  • 91
    • 33744903380 scopus 로고    scopus 로고
    • The NS2 protein of human respiratory syncytial virus suppresses the cytotoxic T-cell response as a consequence of suppressing the type I interferon response
    • Kotelkin, A.; Belyakov, I. M.; Yang, L.; Berzofsky, J. A.; Collins, P. L.; Bukreyev, A. The NS2 protein of human respiratory syncytial virus suppresses the cytotoxic T-cell response as a consequence of suppressing the type I interferon response. J. Virol., 2006, 80(12), 5958-5967.
    • (2006) J. Virol. , vol.80 , Issue.12 , pp. 5958-5967
    • Kotelkin, A.1    Belyakov, I.M.2    Yang, L.3    Berzofsky, J.A.4    Collins, P.L.5    Bukreyev, A.6
  • 92
    • 0242286016 scopus 로고    scopus 로고
    • Evaluation of recombinant respiratory syncytial virus gene deletion mutants in African green monkeys for their potential as live attenuated vaccine candidates
    • Jin, H.; Cheng, X.; Traina-Dorge, V. L.; Park, H. J.; Zhou, H.; Soike, K.; Kemble, G. Evaluation of recombinant respiratory syncytial virus gene deletion mutants in African green monkeys for their potential as live attenuated vaccine candidates. Vaccine, 2003, 21(25-26), 3647-3652.
    • (2003) Vaccine , vol.21 , Issue.25-26 , pp. 3647-3652
    • Jin, H.1    Cheng, X.2    Traina-Dorge, V.L.3    Park, H.J.4    Zhou, H.5    Soike, K.6    Kemble, G.7
  • 93
    • 0033803734 scopus 로고    scopus 로고
    • Recombinant respiratory syncytial virus that does not express the NS1 or M2-2 protein is highly attenuated and immunogenic in chimpanzees
    • Teng, M. N.; Whitehead, S. S.; Bermingham, A.; St Claire, M.; Elkins, W. R.; Murphy, B. R.; Collins, P. L. Recombinant respiratory syncytial virus that does not express the NS1 or M2-2 protein is highly attenuated and immunogenic in chimpanzees. J. Virol., 2000, 74(19), 9317-9321.
    • (2000) J. Virol. , vol.74 , Issue.19 , pp. 9317-9321
    • Teng, M.N.1    Whitehead, S.S.2    Bermingham, A.3    St Claire, M.4    Elkins, W.R.5    Murphy, B.R.6    Collins, P.L.7
  • 94
    • 0032978732 scopus 로고    scopus 로고
    • Recombinant respiratory syncytial virus bearing a deletion of either the NS2 or SH gene is attenuated in chimpanzees
    • Whitehead, S. S.; Bukreyev, A.; Teng, M. N.; Firestone, C. Y.; St Claire, M.; Elkins, W. R.; Collins, P. L.; Murphy, B. R. Recombinant respiratory syncytial virus bearing a deletion of either the NS2 or SH gene is attenuated in chimpanzees. J. Virol., 1999, 73(4), 3438-3442.
    • (1999) J. Virol. , vol.73 , Issue.4 , pp. 3438-3442
    • Whitehead, S.S.1    Bukreyev, A.2    Teng, M.N.3    Firestone, C.Y.4    St Claire, M.5    Elkins, W.R.6    Collins, P.L.7    Murphy, B.R.8
  • 96
    • 50149097541 scopus 로고    scopus 로고
    • Nonstructural proteins 1 and 2 of respiratory syncytial virus suppress maturation of human dendritic cells
    • Munir, S.; Le Nouen, C.; Luongo, C.; Buchholz, U. J.; Collins, P. L.; Bukreyev, A. Nonstructural proteins 1 and 2 of respiratory syncytial virus suppress maturation of human dendritic cells. J. Virol., 2008, 82(17), 8780-8796.
    • (2008) J. Virol. , vol.82 , Issue.17 , pp. 8780-8796
    • Munir, S.1    Le Nouen, C.2    Luongo, C.3    Buchholz, U.J.4    Collins, P.L.5    Bukreyev, A.6
  • 97
  • 100
    • 0141565113 scopus 로고    scopus 로고
    • Genetic recombination during coinfection of two mutants of human respiratory syncytial virus
    • Spann, K. M.; Collins, P. L.; Teng, M. N. Genetic recombination during coinfection of two mutants of human respiratory syncytial virus. J. Virol., 2003, 77(20), 11201-11211.
    • (2003) J. Virol. , vol.77 , Issue.20 , pp. 11201-11211
    • Spann, K.M.1    Collins, P.L.2    Teng, M.N.3
  • 101
    • 68949194431 scopus 로고    scopus 로고
    • Codon stabilization analysis of the "248" temperature sensitive mutation for increased phenotypic stability of respiratory syncytial virus vaccine candidates
    • Luongo, C.; Yang, L.; Winter, C. C.; Spann, K. M.; Murphy, B. R.; Collins, P. L.; Buchholz, U. J. Codon stabilization analysis of the "248" temperature sensitive mutation for increased phenotypic stability of respiratory syncytial virus vaccine candidates. Vaccine, 2009, 27(41), 5667-5676.
    • (2009) Vaccine, , vol.27 , Issue.41 , pp. 5667-5676
    • Luongo, C.1    Yang, L.2    Winter, C.C.3    Spann, K.M.4    Murphy, B.R.5    Collins, P.L.6    Buchholz, U.J.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.