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Volumn 4, Issue 4, 2012, Pages 424-446

Interplay between interferon-mediated innate immunity and porcine reproductive and respiratory syndrome virus

Author keywords

Arterivirus; Interferon; JAK STAT; MDA5; NF B; Non structural proteins; Nsp; Nucleocapsid; PRRS; PRRSV; RIG I

Indexed keywords

2',5' OLIGOADENYLATE SYNTHETASE; ALPHA INTERFERON; BETA INTERFERON; ENHANCEOSOME; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON; INTERFERON BETA PROMOTER STIMULATOR 1; INTERFERON REGULATORY FACTOR 3; JANUS KINASE; NONSTRUCTURAL PROTEIN 1; NONSTRUCTURAL PROTEIN 11; NONSTRUCTURAL PROTEIN 2; NUCLEOCAPSID PROTEIN; PROTEIN INHIBITOR OF ACTIVATED STAT; RETINOIC ACID INDUCIBLE PROTEIN I; STAT1 PROTEIN; STAT2 PROTEIN; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 8; TOLL LIKE RECEPTOR 9; UNCLASSIFIED DRUG; VIRUS PROTEIN;

EID: 84860235854     PISSN: None     EISSN: 19994915     Source Type: Journal    
DOI: 10.3390/v4040424     Document Type: Review
Times cited : (131)

References (103)
  • 3
    • 0033008414 scopus 로고    scopus 로고
    • North American and European porcine reproductive and respiratory syndrome viruses differ in non-structural protein coding regions
    • Allende R.; Lewis, T. L.; Lu, Z.; Rock, D. L.; Kutish, G. F.; Ali, A.; Doster, A. R.; Osorio, F. A. North American and European porcine reproductive and respiratory syndrome viruses differ in non-structural protein coding regions. J. Gen. Virol. 1999, 80, 307-315.
    • (1999) J. Gen. Virol , vol.80 , pp. 307-315
    • Allende, R.1    Lewis, T.L.2    Lu, Z.3    Rock, D.L.4    Kutish, G.F.5    Ali, A.6    Doster, A.R.7    Osorio, F.A.8
  • 4
    • 0032889516 scopus 로고    scopus 로고
    • Porcine reproductive and respiratory syndrome virus comparison: Divergent evolution on two continents
    • Nelsen, C.J.; Murtaugh, M.P.; Faaberg, K.S. Porcine reproductive and respiratory syndrome virus comparison: divergent evolution on two continents. J. Virol. 1999, 73, 270-280.
    • (1999) J. Virol , vol.73 , pp. 270-280
    • Nelsen, C.J.1    Murtaugh, M.P.2    Faaberg, K.S.3
  • 5
    • 77957356729 scopus 로고    scopus 로고
    • Aberrant host immune response induced by highly virulent PRRSV identified by digital gene expression tag profiling
    • Xiao, S.; Mo, D.; Wang, Q.; Jia, J.; Qin, L.; Yu, X.; Niu, Y.; Zhao, X.; Liu, X.; Chen, Y. Aberrant host immune response induced by highly virulent PRRSV identified by digital gene expression tag profiling. BMC Genom. 2010, 11, 544.
    • (2010) BMC Genom , vol.11 , pp. 544
    • Xiao, S.1    Mo, D.2    Wang, Q.3    Jia, J.4    Qin, L.5    Yu, X.6    Niu, Y.7    Zhao, X.8    Liu, X.9    Chen, Y.10
  • 6
    • 0027254342 scopus 로고
    • Molecular characterization of porcine reproductive and respiratory syndrome virus, a member of the arterivirus group
    • Conzelmann, K.K.; Visser, N.; Van Woensel, P.; Thiel, H.J. Molecular characterization of porcine reproductive and respiratory syndrome virus, a member of the arterivirus group. Virology 1993, 193, 329-339.
    • (1993) Virology , vol.193 , pp. 329-339
    • Conzelmann, K.K.1    Visser, N.2    van Woensel, P.3    Thiel, H.J.4
  • 8
    • 0031754151 scopus 로고    scopus 로고
    • The arterivirus replicase. The road from RNA to protein(s), and back again
    • Snijder, E.J. The arterivirus replicase. The road from RNA to protein(s), and back again. Adv. Exp. Med. Biol. 1998, 440, 97-108.
    • (1998) Adv. Exp. Med. Biol , vol.440 , pp. 97-108
    • Snijder, E.J.1
  • 11
    • 79955574664 scopus 로고    scopus 로고
    • Novel structural protein in porcine reproductive and respiratory syndrome virus encoded by an alternative ORF5 present in all arteriviruses
    • Johnson, C.R.; Griggs, T.F.; Gnanandarajah, J.; Murtaugh, M. P. Novel structural protein in porcine reproductive and respiratory syndrome virus encoded by an alternative ORF5 present in all arteriviruses. J. Gen. Virol. 2011, 92, 1107-1116.
    • (2011) J. Gen. Virol , vol.92 , pp. 1107-1116
    • Johnson, C.R.1    Griggs, T.F.2    Gnanandarajah, J.3    Murtaugh, M.P.4
  • 12
    • 0026040484 scopus 로고
    • Equine arteritis virus is not a togavirus but belongs to the coronaviruslike superfamily
    • Boon, J.A.; Snijder, E.J.; Chirnside, E.D.; de Vries, A.A.; Horzinek, M.C.; Spaan, W.J. Equine arteritis virus is not a togavirus but belongs to the coronaviruslike superfamily. J. Virol. 1991, 65, 2910-2920.
    • (1991) J. Virol , vol.65 , pp. 2910-2920
    • Boon, J.A.1    Snijder, E.J.2    Chirnside, E.D.3    de Vries, A.A.4    Horzinek, M.C.5    Spaan, W.J.6
  • 13
    • 0034520364 scopus 로고    scopus 로고
    • Full-length sequence of a Canadian porcine reproductive and respiratory syndrome virus (PRRSV) isolate
    • Wootton, S.; Yoo, D.; Rogan, D. Full-length sequence of a Canadian porcine reproductive and respiratory syndrome virus (PRRSV) isolate. Arch. Virol. 2000, 145, 2297-2323.
    • (2000) Arch. Virol , vol.145 , pp. 2297-2323
    • Wootton, S.1    Yoo, D.2    Rogan, D.3
  • 14
    • 78649322018 scopus 로고    scopus 로고
    • The PRRSV replicase: Exploring the multifunctionality of an intriguing set of nonstructural proteins
    • Fang, Y.; Snijder, E.J. The PRRSV replicase: Exploring the multifunctionality of an intriguing set of nonstructural proteins. Virus Res. 2010, 154, 61-76.
    • (2010) Virus Res , vol.154 , pp. 61-76
    • Fang, Y.1    Snijder, E.J.2
  • 15
    • 0034106003 scopus 로고    scopus 로고
    • Current knowledge on the structural proteins of porcine reproductive and respiratory syndrome (PRRS) virus: Comparison of the North American and European isolates
    • Dea, S.; Gagnon, C.A.; Mardassi, H.; Pirzadeh, B.; Rogan, D. Current knowledge on the structural proteins of porcine reproductive and respiratory syndrome (PRRS) virus: Comparison of the North American and European isolates. Arch. Virol. 2000, 145, 659-688.
    • (2000) Arch. Virol , vol.145 , pp. 659-688
    • Dea, S.1    Gagnon, C.A.2    Mardassi, H.3    Pirzadeh, B.4    Rogan, D.5
  • 16
    • 0028841481 scopus 로고
    • Nucleocapsid protein N of Lelystad virus: Expression by recombinant baculovirus, immunological properties, and suitability for detection of serum antibodies
    • Meulenberg, J.J.; Bende, R.J.; Pol, J.M.; Wensvoort, G.; Moormann, R.J. Nucleocapsid protein N of Lelystad virus: Expression by recombinant baculovirus, immunological properties, and suitability for detection of serum antibodies. Clin. Diagn. Lab. Immunol. 1995, 2, 652-656.
    • (1995) Clin. Diagn. Lab. Immunol , vol.2 , pp. 652-656
    • Meulenberg, J.J.1    Bende, R.J.2    Pol, J.M.3    Wensvoort, G.4    Moormann, R.J.5
  • 17
    • 0030199284 scopus 로고    scopus 로고
    • Intracellular synthesis, processing, and transport of proteins encoded by ORFs 5 to 7 of porcine reproductive and respiratory syndrome virus
    • Mardassi, H.; Massie, B.; Dea, S. Intracellular synthesis, processing, and transport of proteins encoded by ORFs 5 to 7 of porcine reproductive and respiratory syndrome virus. Virology 1996, 221, 98-112.
    • (1996) Virology , vol.221 , pp. 98-112
    • Mardassi, H.1    Massie, B.2    Dea, S.3
  • 18
    • 25144476250 scopus 로고    scopus 로고
    • Envelope protein requirements for the assembly of infectious virions of porcine reproductive and respiratory syndrome virus
    • Wissink, E.H.; Kroese, M.V.; van Wijk, H.A.; Rijsewijk, F.A.; Meulenberg, J.J.; Rottier, P. J. Envelope protein requirements for the assembly of infectious virions of porcine reproductive and respiratory syndrome virus. J. Virol. 2005, 79, 12495-12506.
    • (2005) J. Virol , vol.79 , pp. 12495-12506
    • Wissink, E.H.1    Kroese, M.V.2    van Wijk, H.A.3    Rijsewijk, F.A.4    Meulenberg, J.J.5    Rottier, P.J.6
  • 19
    • 0037383418 scopus 로고    scopus 로고
    • Homo-oligomerization of the porcine reproductive and respiratory syndrome virus nucleocapsid protein and the role of disulfide linkages
    • Wootton, S.K.; Yoo, D. Homo-oligomerization of the porcine reproductive and respiratory syndrome virus nucleocapsid protein and the role of disulfide linkages. J. Virol. 2003, 77, 4546-4557.
    • (2003) J. Virol , vol.77 , pp. 4546-4557
    • Wootton, S.K.1    Yoo, D.2
  • 20
    • 0242363238 scopus 로고    scopus 로고
    • Colocalization and interaction of the porcine arterivirus nucleocapsid protein with the small nucleolar RNA-associated protein fibrillarin
    • Yoo, D.; Wootton, S.K.; Li, G.; Song, C.; Rowland, R. R. Colocalization and interaction of the porcine arterivirus nucleocapsid protein with the small nucleolar RNA-associated protein fibrillarin. J. Virol. 2003, 77, 12173-12183.
    • (2003) J. Virol , vol.77 , pp. 12173-12183
    • Yoo, D.1    Wootton, S.K.2    Li, G.3    Song, C.4    Rowland, R.R.5
  • 21
    • 78649288595 scopus 로고    scopus 로고
    • Modulation of host cell responses and evasion strategies for porcine reproductive and respiratory syndrome virus
    • Yoo, D.; Song, C.; Sun, Y.; Du, Y.; Kim, O.; Liu, H.C. Modulation of host cell responses and evasion strategies for porcine reproductive and respiratory syndrome virus. Virus Res. 2010, 154, 48-60.
    • (2010) Virus Res , vol.154 , pp. 48-60
    • Yoo, D.1    Song, C.2    Sun, Y.3    Du, Y.4    Kim, O.5    Liu, H.C.6
  • 22
    • 36348940608 scopus 로고    scopus 로고
    • Interferons and viruses: An interplay between induction, signalling, antiviral responses and virus countermeasures
    • Randall, R.E.; Goodbourn, S. Interferons and viruses: An interplay between induction, signalling, antiviral responses and virus countermeasures. J. Gen. Virol. 2008, 89, 1-47.
    • (2008) J. Gen. Virol , vol.89 , pp. 1-47
    • Randall, R.E.1    Goodbourn, S.2
  • 23
    • 25444495693 scopus 로고    scopus 로고
    • The yin and yang of type I interferon activity in bacterial infection
    • Decker, T.; Muller, M.; Stockinger, S. The yin and yang of type I interferon activity in bacterial infection. Nat. Rev. Immunol. 2005, 5, 675-687.
    • (2005) Nat. Rev. Immunol , vol.5 , pp. 675-687
    • Decker, T.1    Muller, M.2    Stockinger, S.3
  • 24
    • 33646377870 scopus 로고    scopus 로고
    • Interferon signalling network in innate defence
    • Takaoka, A.; Yanai, H. Interferon signalling network in innate defence. Cell. Microbiol. 2006, 8, 907-922.
    • (2006) Cell. Microbiol , vol.8 , pp. 907-922
    • Takaoka, A.1    Yanai, H.2
  • 25
    • 77955449024 scopus 로고    scopus 로고
    • Differential expression and activity of the porcine type I interferon family
    • Sang, Y.; Rowland, R.R.; Hesse, R.A.; Blecha, F. Differential expression and activity of the porcine type I interferon family. Physiol. Genom. 2010, 42, 248-258.
    • (2010) Physiol. Genom , vol.42 , pp. 248-258
    • Sang, Y.1    Rowland, R.R.2    Hesse, R.A.3    Blecha, F.4
  • 26
    • 0037505362 scopus 로고    scopus 로고
    • The Toll-IL-1 receptor adaptor family grows to five members
    • O'Neill, L.A.; Fitzgerald, K.A.; Bowie, A.G. The Toll-IL-1 receptor adaptor family grows to five members. Trends Immunol. 2003, 24, 286-290.
    • (2003) Trends Immunol , vol.24 , pp. 286-290
    • O'Neill, L.A.1    Fitzgerald, K.A.2    Bowie, A.G.3
  • 28
    • 34249707811 scopus 로고    scopus 로고
    • TLR-dependent and TLR- independent pathways of type I interferon induction in systemic autoimmunity
    • Baccala, R.; Hoebe, K.; Kono, D.H.; Beutler, B.; Theofilopoulos, A. N. TLR-dependent and TLR- independent pathways of type I interferon induction in systemic autoimmunity. Nat. Med. 2007, 13, 543-551.
    • (2007) Nat. Med , vol.13 , pp. 543-551
    • Baccala, R.1    Hoebe, K.2    Kono, D.H.3    Beutler, B.4    Theofilopoulos, A.N.5
  • 30
    • 1842477469 scopus 로고    scopus 로고
    • A mRNA is an endogenous ligand for Toll-like receptor 3
    • Kariko, K.; Ni, H.; Capodici, J.; Lamphier, M.; Weissman, D. mRNA is an endogenous ligand for Toll-like receptor 3. J. Biol. Chem. 2004, 279, 12542-12550.
    • (2004) J. Biol. Chem , vol.279 , pp. 12542-12550
    • Kariko, K.1    Ni, H.2    Capodici, J.3    Lamphier, M.4    Weissman, D.5
  • 31
    • 26944469056 scopus 로고    scopus 로고
    • Interferon-beta induction through toll-like receptor 3 depends on double-stranded RNA structure
    • Okahira, S.; Nishikawa, F.; Nishikawa, S.; Akazawa, T.; Seya, T.; Matsumoto, M. Interferon-beta induction through toll-like receptor 3 depends on double-stranded RNA structure. DNA Cell Biol. 2005, 24, 614-623.
    • (2005) DNA Cell Biol , vol.24 , pp. 614-623
    • Okahira, S.1    Nishikawa, F.2    Nishikawa, S.3    Akazawa, T.4    Seya, T.5    Matsumoto, M.6
  • 32
    • 38549138306 scopus 로고    scopus 로고
    • Sensing of viral infection and activation of innate immunity by toll-like receptor 3
    • Vercammen, E.; Staal, J.; Beyaert, R. Sensing of viral infection and activation of innate immunity by toll-like receptor 3. Clin. Microbiol. Rev. 2008, 21, 13-25.
    • (2008) Clin. Microbiol. Rev , vol.21 , pp. 13-25
    • Vercammen, E.1    Staal, J.2    Beyaert, R.3
  • 33
    • 37849012459 scopus 로고    scopus 로고
    • The interplay between viruses and innate immune signaling: Recent insights and therapeutic opportunities
    • Unterholzner, L.; Bowie, A.G. The interplay between viruses and innate immune signaling: Recent insights and therapeutic opportunities. Biochem. Pharmacol. 2008, 75, 589-602.
    • (2008) Biochem. Pharmacol , vol.75 , pp. 589-602
    • Unterholzner, L.1    Bowie, A.G.2
  • 34
    • 34548129595 scopus 로고    scopus 로고
    • The response of mammalian cells to double-stranded RNA
    • Gantier, M.P.; Williams, B.R. The response of mammalian cells to double-stranded RNA. Cytokine Growth Factor Rev. 2007, 18, 363-371.
    • (2007) Cytokine Growth Factor Rev , vol.18 , pp. 363-371
    • Gantier, M.P.1    Williams, B.R.2
  • 36
    • 34247566510 scopus 로고    scopus 로고
    • The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling
    • O'Neill, L.A.; Bowie, A.G. The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling. Nat. Rev. Immunol. 2007, 7, 353-364.
    • (2007) Nat. Rev. Immunol , vol.7 , pp. 353-364
    • O'Neill, L.A.1    Bowie, A.G.2
  • 37
    • 32644456874 scopus 로고    scopus 로고
    • Antiviral innate immunity pathways
    • Seth, R.B.; Sun, L.; Chen, Z.J. Antiviral innate immunity pathways. Cell Res. 2006, 16, 141-147.
    • (2006) Cell Res , vol.16 , pp. 141-147
    • Seth, R.B.1    Sun, L.2    Chen, Z.J.3
  • 38
    • 35048827114 scopus 로고    scopus 로고
    • Signalling pathways mediating tsype I interferon gene expression
    • Edwards, M.R.; Slater, L.; Johnston, S.L. Signalling pathways mediating tsype I interferon gene expression. Microb. Infect. 2007, 9, 1245-1251.
    • (2007) Microb. Infect , vol.9 , pp. 1245-1251
    • Edwards, M.R.1    Slater, L.2    Johnston, S.L.3
  • 39
    • 33748475531 scopus 로고    scopus 로고
    • Type I interferon [corrected] gene induction by the interferon regulatory factor family of transcription factors
    • Honda, K.; Takaoka, A.; Taniguchi, T. Type I interferon [corrected] gene induction by the interferon regulatory factor family of transcription factors. Immunity 2006, 25, 349-360.
    • (2006) Immunity , vol.25 , pp. 349-360
    • Honda, K.1    Takaoka, A.2    Taniguchi, T.3
  • 40
    • 56749133272 scopus 로고    scopus 로고
    • Viral evasion and subversion of pattern-recognition receptor signalling
    • Bowie, A.G.; Unterholzner, L. Viral evasion and subversion of pattern-recognition receptor signalling. Nat. Rev. Immunol. 2008, 8, 911-922.
    • (2008) Nat. Rev. Immunol , vol.8 , pp. 911-922
    • Bowie, A.G.1    Unterholzner, L.2
  • 42
    • 33845431988 scopus 로고    scopus 로고
    • RNA- and virus-independent inhibition of antiviral signaling by RNA helicase LGP2
    • Komuro, A.; Horvath, C. M. RNA- and virus-independent inhibition of antiviral signaling by RNA helicase LGP2. J. Virol. 2006, 80, 12332-12342.
    • (2006) J. Virol , vol.80 , pp. 12332-12342
    • Komuro, A.1    Horvath, C.M.2
  • 44
    • 24144461689 scopus 로고    scopus 로고
    • Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3
    • Seth, R.B.; Sun, L.; Ea, C.K.; Chen, Z.J. Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3. Cell 2005, 122, 669-682.
    • (2005) Cell , vol.122 , pp. 669-682
    • Seth, R.B.1    Sun, L.2    Ea, C.K.3    Chen, Z.J.4
  • 49
    • 0029069145 scopus 로고
    • Transcriptional responses to polypeptide ligands: The JAK-STAT pathway
    • Schindler, C.; Darnell, J.E., Jr. Transcriptional responses to polypeptide ligands: The JAK-STAT pathway. Annu. Rev. Biochem. 1995, 64, 621-651.
    • (1995) Annu. Rev. Biochem , vol.64 , pp. 621-651
    • Schindler, C.1    Darnell Jr., J.E.2
  • 50
    • 0034801684 scopus 로고    scopus 로고
    • SOCS proteins: Negative regulators of cytokine signaling
    • Krebs, D.L.; Hilton, D.J. SOCS proteins: Negative regulators of cytokine signaling. Stem Cell. 2001, 19, 378-387.
    • (2001) Stem Cell , vol.19 , pp. 378-387
    • Krebs, D.L.1    Hilton, D.J.2
  • 51
    • 23444461182 scopus 로고    scopus 로고
    • Regulation of gene-activation pathways by PIAS proteins in the immune system
    • Shuai, K.; Liu, B. Regulation of gene-activation pathways by PIAS proteins in the immune system. Nat. Rev. Immunol. 2005, 5, 593-605.
    • (2005) Nat. Rev. Immunol , vol.5 , pp. 593-605
    • Shuai, K.1    Liu, B.2
  • 52
    • 77952566949 scopus 로고    scopus 로고
    • Mechanisms, regulation and consequences of protein SUMOylation
    • Wilkinson, K.A.; Henley, J. M. Mechanisms, regulation and consequences of protein SUMOylation. Biochem. J. 2010, 428, 133-145.
    • (2010) Biochem. J , vol.428 , pp. 133-145
    • Wilkinson, K.A.1    Henley, J.M.2
  • 53
    • 46249115827 scopus 로고    scopus 로고
    • Interferon-inducible antiviral effectors
    • Sadler, A.J.; Williams, B.R. Interferon-inducible antiviral effectors. Nat. Rev. Immunol. 2008, 8, 559-568.
    • (2008) Nat. Rev. Immunol , vol.8 , pp. 559-568
    • Sadler, A.J.1    Williams, B.R.2
  • 54
    • 0022981641 scopus 로고
    • Molecular characterization of the interferon-induced 15-kDa protein. Molecular cloning and nucleotide and amino acid sequence
    • Blomstrom, D.C.; Fahey, D.; Kutny, R.; Korant, B.D.; Knight, E., Jr. Molecular characterization of the interferon-induced 15-kDa protein. Molecular cloning and nucleotide and amino acid sequence. J. Biol. Chem. 1986, 261, 8811-8816.
    • (1986) J. Biol. Chem , vol.261 , pp. 8811-8816
    • Blomstrom, D.C.1    Fahey, D.2    Kutny, R.3    Korant, B.D.4    Knight Jr., E.5
  • 55
    • 0030042942 scopus 로고    scopus 로고
    • Conjugation of the 15-kDa interferon-induced ubiquitin homolog is distinct from that of ubiquitin
    • Narasimhan, J.; Potter, J.L.; Haas, A.L. Conjugation of the 15-kDa interferon-induced ubiquitin homolog is distinct from that of ubiquitin. J. Biol. Chem. 1996, 271, 324-330.
    • (1996) J. Biol. Chem , vol.271 , pp. 324-330
    • Narasimhan, J.1    Potter, J.L.2    Haas, A.L.3
  • 57
    • 0030292679 scopus 로고    scopus 로고
    • In vitro and in vivo secretion of human ISG15, an IFN-induced immunomodulatory cytokine
    • D'Cunha, J.; Ramanujam, S.; Wagner, R.J.; Witt, P.L.; Knight, E., Jr.; Borden, E.C. In vitro and in vivo secretion of human ISG15, an IFN-induced immunomodulatory cytokine. J. Immunol. 1996, 157, 4100-4108.
    • (1996) J. Immunol , vol.157 , pp. 4100-4108
    • D'cunha, J.1    Ramanujam, S.2    Wagner, R.J.3    Witt, P.L.4    Knight Jr., E.5    Borden, E.C.6
  • 58
    • 0018869587 scopus 로고
    • Host gene influences sensitivity to interferon action selectively for influenza virus
    • Haller, O.; Arnheiter, H.; Lindenmann, J.; Gresser, I. Host gene influences sensitivity to interferon action selectively for influenza virus. Nature 1980, 283, 660-662.
    • (1980) Nature , vol.283 , pp. 660-662
    • Haller, O.1    Arnheiter, H.2    Lindenmann, J.3    Gresser, I.4
  • 59
    • 0028944742 scopus 로고
    • Tick-borne thogoto virus infection in mice is inhibited by the orthomyxovirus resistance gene product Mx1
    • Haller, O.; Frese, M.; Rost, D.; Nuttall, P.A.; Kochs, G. Tick-borne thogoto virus infection in mice is inhibited by the orthomyxovirus resistance gene product Mx1. J. Virol. 1995, 69, 2596-2601.
    • (1995) J. Virol , vol.69 , pp. 2596-2601
    • Haller, O.1    Frese, M.2    Rost, D.3    Nuttall, P.A.4    Kochs, G.5
  • 60
    • 0033514947 scopus 로고    scopus 로고
    • Interferon-induced human MxA GTPase blocks nuclear import of Thogoto virus nucleocapsids
    • Kochs, G.; Haller, O. Interferon-induced human MxA GTPase blocks nuclear import of Thogoto virus nucleocapsids. Proc. Natl. Acad. Sci. U. S. A. 1999, 96, 2082-2086.
    • (1999) Proc. Natl. Acad. Sci. U. S. A , vol.96 , pp. 2082-2086
    • Kochs, G.1    Haller, O.2
  • 61
    • 34347206680 scopus 로고    scopus 로고
    • The human 2'-5'oligoadenylate synthetase family: Unique interferon-inducible enzymes catalyzing 2'-5' instead of 3'-5' phosphodiester bond formation
    • Hovanessian, A.G.; Justesen, J. The human 2'-5'oligoadenylate synthetase family: Unique interferon-inducible enzymes catalyzing 2'-5' instead of 3'-5' phosphodiester bond formation. Biochimie 2007, 89, 779-788.
    • (2007) Biochimie , vol.89 , pp. 779-788
    • Hovanessian, A.G.1    Justesen, J.2
  • 62
    • 0017176867 scopus 로고
    • Interferon-mediated protein kinase and low-molecular-weight inhibitor of protein synthesis
    • Roberts, W.K.; Hovanessian, A.; Brown, R.E.; Clemens, M.J.; Kerr, I.M. Interferon-mediated protein kinase and low-molecular-weight inhibitor of protein synthesis. Nature 1976, 264, 477-480.
    • (1976) Nature , vol.264 , pp. 477-480
    • Roberts, W.K.1    Hovanessian, A.2    Brown, R.E.3    Clemens, M.J.4    Kerr, I.M.5
  • 64
    • 0032530310 scopus 로고    scopus 로고
    • Structure of the double-stranded RNA-binding domain of the protein kinase PKR reveals the molecular basis of its dsRNA- mediated activation
    • Nanduri, S.; Carpick, B.W.; Yang, Y.; Williams, B.R.; Qin, J. Structure of the double-stranded RNA-binding domain of the protein kinase PKR reveals the molecular basis of its dsRNA- mediated activation. EMBO J. 1998, 17, 5458-5465.
    • (1998) EMBO J , vol.17 , pp. 5458-5465
    • Nanduri, S.1    Carpick, B.W.2    Yang, Y.3    Williams, B.R.4    Qin, J.5
  • 66
    • 0033999869 scopus 로고    scopus 로고
    • Porcine reproductive and respiratory syndrome virus (PRRSV): Kinetics of infection in lymphatic organs and lung
    • Beyer, J.; Fichtner, D.; Schirrmeier, H.; Polster, U.; Weiland, E.; Wege, H. Porcine reproductive and respiratory syndrome virus (PRRSV): Kinetics of infection in lymphatic organs and lung. J. Vet. Med. B 2000, 47, 9-25.
    • (2000) J. Vet. Med. B , vol.47 , pp. 9-25
    • Beyer, J.1    Fichtner, D.2    Schirrmeier, H.3    Polster, U.4    Weiland, E.5    Wege, H.6
  • 67
    • 1542502616 scopus 로고    scopus 로고
    • Lymphoid tissue tropism of porcine reproductive and respiratory syndrome virus replication during persistent infection of pigs originally exposed to virus in utero
    • Rowland, R.R.; Lawson, S.; Rossow, K.; Benfield, D.A. Lymphoid tissue tropism of porcine reproductive and respiratory syndrome virus replication during persistent infection of pigs originally exposed to virus in utero. Vet. Microbiol. 2003, 96, 219-235.
    • (2003) Vet. Microbiol , vol.96 , pp. 219-235
    • Rowland, R.R.1    Lawson, S.2    Rossow, K.3    Benfield, D.A.4
  • 69
    • 0032536578 scopus 로고    scopus 로고
    • Immune responses in pigs infected with porcine reproductive and respiratory syndrome virus (PRRSV)
    • Albina, E.; Piriou, L.; Hutet, E.; Cariolet, R.; L'Hospitalier, R. Immune responses in pigs infected with porcine reproductive and respiratory syndrome virus (PRRSV). Vet. Immunol. Immunopathol. 1998, 61, 49-66.
    • (1998) Vet. Immunol. Immunopathol , vol.61 , pp. 49-66
    • Albina, E.1    Piriou, L.2    Hutet, E.3    Cariolet, R.4    L'hospitalier, R.5
  • 70
    • 0033175579 scopus 로고    scopus 로고
    • Differential production of proinflammatory cytokines in the pig lung during different respiratory virus infections: Correlations with pathogenicity
    • Van Reeth, K.; Labarque, G.; Nauwynck, H.; Pensaert, M. Differential production of proinflammatory cytokines in the pig lung during different respiratory virus infections: Correlations with pathogenicity. Res. Vet. Sci. 1999, 67, 47-52.
    • (1999) Res. Vet. Sci , vol.67 , pp. 47-52
    • van Reeth, K.1    Labarque, G.2    Nauwynck, H.3    Pensaert, M.4
  • 71
    • 0031751351 scopus 로고    scopus 로고
    • In vivo and in vitro interferon (IFN) studies with the porcine reproductive and respiratory syndrome virus (PRRSV)
    • Buddaert, W.; Van Reeth, K.; Pensaert, M. In vivo and in vitro interferon (IFN) studies with the porcine reproductive and respiratory syndrome virus (PRRSV). Adv. Exp. Med. Biol. 1998, 440, 461-467.
    • (1998) Adv. Exp. Med. Biol , vol.440 , pp. 461-467
    • Buddaert, W.1    van Reeth, K.2    Pensaert, M.3
  • 72
    • 7044286680 scopus 로고    scopus 로고
    • Interferon type I response in porcine reproductive and respiratory syndrome virus-infected MARC-145 cells
    • Miller, L.C.; Laegreid, W.W.; Bono, J.L.; Chitko-McKown, C.G.; Fox, J.M. Interferon type I response in porcine reproductive and respiratory syndrome virus-infected MARC-145 cells. Arch. Virol. 2004, 149, 2453-2463.
    • (2004) Arch. Virol , vol.149 , pp. 2453-2463
    • Miller, L.C.1    Laegreid, W.W.2    Bono, J.L.3    Chitko-McKown, C.G.4    Fox, J.M.5
  • 73
    • 41849125938 scopus 로고    scopus 로고
    • Porcine reproductive and respiratory syndrome virus (PRRSV) suppresses interferon-beta production by interfering with the RIG-I signaling pathway
    • Luo, R.; Xiao, S.; Jiang, Y.; Jin, H.; Wang, D.; Liu, M.; Chen, H.; Fang, L. Porcine reproductive and respiratory syndrome virus (PRRSV) suppresses interferon-beta production by interfering with the RIG-I signaling pathway. Mol. Immunol. 2008, 45, 2839-2846.
    • (2008) Mol. Immunol , vol.45 , pp. 2839-2846
    • Luo, R.1    Xiao, S.2    Jiang, Y.3    Jin, H.4    Wang, D.5    Liu, M.6    Chen, H.7    Fang, L.8
  • 74
    • 79959741244 scopus 로고    scopus 로고
    • Host inhibits replication of European porcine reproductive and respiratory syndrome virus in macrophages by altering differential regulation of type-I interferon transcriptional response
    • Ait-Ali, T.; Wilson, A.D.; Carre, W.; Westcott, D.G.; Frossard, J.P.; Mellencamp, M.A.; Mouzaki, D.; Matika, O.; Waddington, D.; Drew, T. W.; et al. Host inhibits replication of European porcine reproductive and respiratory syndrome virus in macrophages by altering differential regulation of type-I interferon transcriptional response. Immunogenetics 2011, 63, 437-448.
    • (2011) Immunogenetics , vol.63 , pp. 437-448
    • Ait-Ali, T.1    Wilson, A.D.2    Carre, W.3    Westcott, D.G.4    Frossard, J.P.5    Mellencamp, M.A.6    Mouzaki, D.7    Matika, O.8    Waddington, D.9    Drew, T.W.10
  • 75
    • 33845363285 scopus 로고    scopus 로고
    • Toll-like receptor 2 and 9 are expressed and functional in gut-associated lymphoid tissues of presuckling newborn swine
    • Tohno, M.; Shimosato, T.; Moue, M.; Aso, H.; Watanabe, K.; Kawai, Y.; Yamaguchi, T.; Saito, T.; Kitazawa, H. Toll-like receptor 2 and 9 are expressed and functional in gut-associated lymphoid tissues of presuckling newborn swine. Vet. Res. 2006, 37, 791-812.
    • (2006) Vet. Res , vol.37 , pp. 791-812
    • Tohno, M.1    Shimosato, T.2    Moue, M.3    Aso, H.4    Watanabe, K.5    Kawai, Y.6    Yamaguchi, T.7    Saito, T.8    Kitazawa, H.9
  • 76
    • 51849157938 scopus 로고    scopus 로고
    • Toll-like receptor 3 activation decreases porcine arterivirus infection
    • Sang, Y.; Ross, C.R.; Rowland, R.R.; Blecha, F. Toll-like receptor 3 activation decreases porcine arterivirus infection. Viral. Immunol. 2008, 21, 303-313.
    • (2008) Viral. Immunol , vol.21 , pp. 303-313
    • Sang, Y.1    Ross, C.R.2    Rowland, R.R.3    Blecha, F.4
  • 77
    • 49049084418 scopus 로고    scopus 로고
    • Molecular identification and functional expression of porcine Toll-like receptor (TLR) 3 and TLR7
    • Sang, Y.; Yang, J.; Ross, C.R.; Rowland, R.R.; Blecha, F. Molecular identification and functional expression of porcine Toll-like receptor (TLR) 3 and TLR7. Vet. Immunol. Immunopathol. 2008, 125, 162-167.
    • (2008) Vet. Immunol. Immunopathol , vol.125 , pp. 162-167
    • Sang, Y.1    Yang, J.2    Ross, C.R.3    Rowland, R.R.4    Blecha, F.5
  • 78
    • 77951024349 scopus 로고    scopus 로고
    • Toll-Like Receptor expressions in porcine alveolar macrophages and Dendritic Cells in responding to poly IC stimulation and porcine reproductive and respiratory syndrome virus (PRRSV) infection
    • Chaung, H.C.; Chen, C.W.; Hsieh, B.L.; Chung, W.B. Toll-Like Receptor expressions in porcine alveolar macrophages and Dendritic Cells in responding to poly IC stimulation and porcine reproductive and respiratory syndrome virus (PRRSV) infection. Comp. Immunol. Microbiol. Infect. Dis. 2010, 33, 197-213.
    • (2010) Comp. Immunol. Microbiol. Infect. Dis , vol.33 , pp. 197-213
    • Chaung, H.C.1    Chen, C.W.2    Hsieh, B.L.3    Chung, W.B.4
  • 79
    • 61949292361 scopus 로고    scopus 로고
    • Role of Toll-like receptors in activation of porcine alveolar macrophages by porcine reproductive and respiratory syndrome virus
    • Miller, L.C.; Lager, K.M.; Kehrli, M. E., Jr. Role of Toll-like receptors in activation of porcine alveolar macrophages by porcine reproductive and respiratory syndrome virus. Clin. Vaccine Immunol. 2009, 16, 360-365.
    • (2009) Clin. Vaccine Immunol , vol.16 , pp. 360-365
    • Miller, L.C.1    Lager, K.M.2    Kehrli Jr., M.E.3
  • 80
    • 77953028825 scopus 로고    scopus 로고
    • Modulation of type I interferon induction by porcine reproductive and respiratory syndrome virus and degradation of CREB-binding protein by non-structural protein 1 in MARC-145 and HeLa cells
    • Kim, O.; Sun, Y.; Lai, F.W.; Song, C.; Yoo, D. Modulation of type I interferon induction by porcine reproductive and respiratory syndrome virus and degradation of CREB-binding protein by non-structural protein 1 in MARC-145 and HeLa cells. Virology 2010, 402, 315-326.
    • (2010) Virology , vol.402 , pp. 315-326
    • Kim, O.1    Sun, Y.2    Lai, F.W.3    Song, C.4    Yoo, D.5
  • 81
    • 78650053747 scopus 로고    scopus 로고
    • The cysteine protease domain of porcine reproductive and respiratory syndrome virus non-structural protein 2 antagonizes interferon regulatory factor 3 activation
    • Li, H.; Zheng, Z.; Zhou, P.; Zhang, B.; Shi, Z.; Hu, Q.; Wang, H. The cysteine protease domain of porcine reproductive and respiratory syndrome virus non-structural protein 2 antagonizes interferon regulatory factor 3 activation. J. Gen. Virol. 2010, 91, 2947-2958.
    • (2010) J. Gen. Virol , vol.91 , pp. 2947-2958
    • Li, H.1    Zheng, Z.2    Zhou, P.3    Zhang, B.4    Shi, Z.5    Hu, Q.6    Wang, H.7
  • 82
    • 66149091584 scopus 로고    scopus 로고
    • Biochemical characterization of arterivirus nonstructural protein 11 reveals the nidovirus-wide conservation of a replicative endoribonuclease
    • Nedialkova, D.D.; Ulferts, R.; van den Born, E.; Lauber, C.; Gorbalenya, A.E.; Ziebuhr, J.; Snijder, E.J. Biochemical characterization of arterivirus nonstructural protein 11 reveals the nidovirus-wide conservation of a replicative endoribonuclease. J. Virol. 2009, 83, 5671-5682.
    • (2009) J. Virol , vol.83 , pp. 5671-5682
    • Nedialkova, D.D.1    Ulferts, R.2    van den Born, E.3    Lauber, C.4    Gorbalenya, A.E.5    Ziebuhr, J.6    Snijder, E.J.7
  • 83
    • 27444448127 scopus 로고    scopus 로고
    • Porcine arterivirus activates the NF-kappaB pathway through IkappaB degradation
    • Lee, S.M.; Kleiboeker, S.B. Porcine arterivirus activates the NF-kappaB pathway through IkappaB degradation. Virology 2005, 342, 47-59.
    • (2005) Virology , vol.342 , pp. 47-59
    • Lee, S.M.1    Kleiboeker, S.B.2
  • 84
    • 79952435739 scopus 로고    scopus 로고
    • North American porcine reproductive and respiratory syndrome viruses inhibit type I interferon production by plasmacytoid dendritic cells
    • Calzada-Nova, G.; Schnitzlein, W.M.; Husmann, R.J.; Zuckermann, F. A. North American porcine reproductive and respiratory syndrome viruses inhibit type I interferon production by plasmacytoid dendritic cells. J. Virol. 2011, 85, 2703-2713.
    • (2011) J. Virol , vol.85 , pp. 2703-2713
    • Calzada-Nova, G.1    Schnitzlein, W.M.2    Husmann, R.J.3    Zuckermann, F.A.4
  • 85
    • 77957674435 scopus 로고    scopus 로고
    • Nonstructural protein 1alpha subunit-based inhibition of NF-kappaB activation and suppression of interferon-beta production by porcine reproductive and respiratory syndrome virus
    • Song, C.; Krell, P.; Yoo, D. Nonstructural protein 1alpha subunit-based inhibition of NF-kappaB activation and suppression of interferon-beta production by porcine reproductive and respiratory syndrome virus. Virology 2010, 407, 268-280.
    • (2010) Virology , vol.407 , pp. 268-280
    • Song, C.1    Krell, P.2    Yoo, D.3
  • 88
    • 77954461006 scopus 로고    scopus 로고
    • The cysteine protease domain of porcine reproductive and respiratory syndrome virus nonstructural protein 2 possesses deubiquitinating and interferon antagonism functions
    • Sun, Z.; Chen, Z.; Lawson, S.R.; Fang, Y. The cysteine protease domain of porcine reproductive and respiratory syndrome virus nonstructural protein 2 possesses deubiquitinating and interferon antagonism functions. J. Virol. 2010, 84, 7832-7846.
    • (2010) J. Virol , vol.84 , pp. 7832-7846
    • Sun, Z.1    Chen, Z.2    Lawson, S.R.3    Fang, Y.4
  • 89
    • 77957931265 scopus 로고    scopus 로고
    • Porcine reproductive and respiratory syndrome virus inhibits type I interferon signaling by blocking STAT1/STAT2 nuclear translocation
    • Patel, D.; Nan, Y.; Shen, M.; Ritthipichai, K.; Zhu, X.; Zhang, Y.J. Porcine reproductive and respiratory syndrome virus inhibits type I interferon signaling by blocking STAT1/STAT2 nuclear translocation. J. Virol. 2010, 84, 11045-11055.
    • (2010) J. Virol , vol.84 , pp. 11045-11055
    • Patel, D.1    Nan, Y.2    Shen, M.3    Ritthipichai, K.4    Zhu, X.5    Zhang, Y.J.6
  • 90
    • 75849149994 scopus 로고    scopus 로고
    • Identification of two auto-cleavage products of nonstructural protein 1 (nsp1) in porcine reproductive and respiratory syndrome virus infected cells: Nsp1 function as interferon antagonist
    • Chen, Z.; Lawson, S.; Sun, Z.; Zhou, X.; Guan, X.; Christopher-Hennings, J.; Nelson, E.A.; Fang, Y. Identification of two auto-cleavage products of nonstructural protein 1 (nsp1) in porcine reproductive and respiratory syndrome virus infected cells: nsp1 function as interferon antagonist. Virology 2010, 398, 87-97.
    • (2010) Virology , vol.398 , pp. 87-97
    • Chen, Z.1    Lawson, S.2    Sun, Z.3    Zhou, X.4    Guan, X.5    Christopher-Hennings, J.6    Nelson, E.A.7    Fang, Y.8
  • 92
    • 0035096556 scopus 로고    scopus 로고
    • Inhibition of porcine reproductive and respiratory syndrome virus by interferon-gamma and recovery of virus replication with 2-aminopurine
    • Rowland, R.R.; Robinson, B.; Stefanick, J.; Kim, T.S.; Guanghua, L.; Lawson, S.R.; Benfield, D.A. Inhibition of porcine reproductive and respiratory syndrome virus by interferon-gamma and recovery of virus replication with 2-aminopurine. Arch. Virol. 2001, 146, 539-555.
    • (2001) Arch. Virol , vol.146 , pp. 539-555
    • Rowland, R.R.1    Robinson, B.2    Stefanick, J.3    Kim, T.S.4    Guanghua, L.5    Lawson, S.R.6    Benfield, D.A.7
  • 93
    • 0029937848 scopus 로고    scopus 로고
    • Open reading frame 5 of porcine reproductive and respiratory syndrome virus as a cause of virusinduced apoptosis
    • Suarez, P.; Diaz-Guerra, M.; Prieto, C.; Esteban, M.; Castro, J.M.; Nieto, A.; Ortin, J. Open reading frame 5 of porcine reproductive and respiratory syndrome virus as a cause of virusinduced apoptosis. J. Virol. 1996, 70, 2876-2882.
    • (1996) J. Virol , vol.70 , pp. 2876-2882
    • Suarez, P.1    Diaz-Guerra, M.2    Prieto, C.3    Esteban, M.4    Castro, J.M.5    Nieto, A.6    Ortin, J.7
  • 94
    • 0032408195 scopus 로고    scopus 로고
    • A pneumo-virulent United States isolate of porcine reproductive and respiratory syndrome virus induces apoptosis in bystander cells both in vitro and in vivo
    • Sirinarumitr, T.; Zhang, Y.; Kluge, J.P.; Halbur, P.G.; Paul, P.S. A pneumo-virulent United States isolate of porcine reproductive and respiratory syndrome virus induces apoptosis in bystander cells both in vitro and in vivo. J. Gen. Virol. 1998, 79, 2989-2995.
    • (1998) J. Gen. Virol , vol.79 , pp. 2989-2995
    • Sirinarumitr, T.1    Zhang, Y.2    Kluge, J.P.3    Halbur, P.G.4    Paul, P.S.5
  • 95
    • 0032199236 scopus 로고    scopus 로고
    • Apoptosis induced in vivo during acute infection by porcine reproductive and respiratory syndrome virus
    • Sur, J.H.; Doster, A.R.; Osorio, F.A. Apoptosis induced in vivo during acute infection by porcine reproductive and respiratory syndrome virus. Vet. Pathol. 1998, 35, 506-514.
    • (1998) Vet. Pathol , vol.35 , pp. 506-514
    • Sur, J.H.1    Doster, A.R.2    Osorio, F.A.3
  • 96
    • 0037176728 scopus 로고    scopus 로고
    • Characterization of regions in the GP5 protein of porcine reproductive and respiratory syndrome virus required to induce apoptotic cell death
    • Fernandez, A.; Suarez, P.; Castro, J.M.; Tabares, E.; Diaz-Guerra, M. Characterization of regions in the GP5 protein of porcine reproductive and respiratory syndrome virus required to induce apoptotic cell death. Virus Res. 2002, 83, 103-118.
    • (2002) Virus Res , vol.83 , pp. 103-118
    • Fernandez, A.1    Suarez, P.2    Castro, J.M.3    Tabares, E.4    Diaz-Guerra, M.5
  • 97
    • 7044264364 scopus 로고    scopus 로고
    • Apoptosis and porcine reproductive and respiratory syndrome virus
    • Miller, L.C.; Fox, J.M. Apoptosis and porcine reproductive and respiratory syndrome virus. Vet. Immunol. Immunopathol. 2004, 102, 131-142.
    • (2004) Vet. Immunol. Immunopathol , vol.102 , pp. 131-142
    • Miller, L.C.1    Fox, J.M.2
  • 98
    • 47549094091 scopus 로고    scopus 로고
    • Porcine reproductive and respiratory syndrome virus modulates apoptosis during replication in alveolar macrophages
    • Costers, S.; Lefebvre, D.J.; Delputte, P.L.; Nauwynck, H.J. Porcine reproductive and respiratory syndrome virus modulates apoptosis during replication in alveolar macrophages. Arch. Virol. 2008, 153, 1453-1465.
    • (2008) Arch. Virol , vol.153 , pp. 1453-1465
    • Costers, S.1    Lefebvre, D.J.2    Delputte, P.L.3    Nauwynck, H.J.4
  • 99
    • 33846414395 scopus 로고    scopus 로고
    • Porcine reproductive and respiratory syndrome virus productively infects monocyte-derived dendritic cells and compromises their antigen-presenting ability
    • Wang, X.; Eaton, M.; Mayer, M.; Li, H.; He, D.; Nelson, E.; Christopher-Hennings, J. Porcine reproductive and respiratory syndrome virus productively infects monocyte-derived dendritic cells and compromises their antigen-presenting ability. Arch. Virol. 2007, 152, 289-303.
    • (2007) Arch. Virol , vol.152 , pp. 289-303
    • Wang, X.1    Eaton, M.2    Mayer, M.3    Li, H.4    He, D.5    Nelson, E.6    Christopher-Hennings, J.7
  • 101
    • 7044249190 scopus 로고    scopus 로고
    • Porcine reproductive and respiratory syndrome virus field isolates differ in in vitro interferon phenotypes
    • Lee, S.M.; Schommer, S.K.; Kleiboeker, S. B. Porcine reproductive and respiratory syndrome virus field isolates differ in in vitro interferon phenotypes. Vet. Immunol. Immunopathol. 2004, 102, 217-231.
    • (2004) Vet. Immunol. Immunopathol , vol.102 , pp. 217-231
    • Lee, S.M.1    Schommer, S.K.2    Kleiboeker, S.B.3
  • 102
    • 78650179663 scopus 로고    scopus 로고
    • Marked differences between MARC-145 cells and swine alveolar macrophages in IFNbeta-induced activation of antiviral state against PRRSV
    • He, D.; Overend, C.; Ambrogio, J.; Maganti, R.J.; Grubman, M.J.; Garmendia, A.E. Marked differences between MARC-145 cells and swine alveolar macrophages in IFNbeta-induced activation of antiviral state against PRRSV. Vet. Immunol. Immunopathol. 2011, 139, 57-60.
    • (2011) Vet. Immunol. Immunopathol , vol.139 , pp. 57-60
    • He, D.1    Overend, C.2    Ambrogio, J.3    Maganti, R.J.4    Grubman, M.J.5    Garmendia, A.E.6


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