The arterivirus replicase: The road from RNA to protein(s), and back again

Advances in Experimental Medicine and Biology

Volumn 440, Issue , 1998, Pages 97-108

  Snijder, Eric J ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

RNA DIRECTED RNA POLYMERASE;

AMINO ACID SEQUENCE; ARTERIVIRUS; ARTICLE; ENZYME ACTIVATION; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN PROCESSING; VIRUS CHARACTERIZATION; VIRUS GENOME; VIRUS REPLICATION; VIRUS TRANSCRIPTION;

ARTERIVIRUS;

EID: 0031754151     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4615-5331-1_13     Document Type: Article

References (55)

1. Baker, S. C., Yokomori, K., Dong, S., Carlisle, R., Gorbalenya, A. E., Koonin, E. V., and Lai, M. M., 1993, Identification of the catalytic sites of a papain-like cysteine proteinase of murine coronavirus, J. Virol. 67:6056-6063.
2. Bazan, J. F., and Fletterick, R. J., 1988, Viral cysteine proteases are homologous to the trypsin-like family of serine proteases: structural and functional implications, Proc. Natl. Acad. Sci. USA 85:7872-7876.
3. Bazan, J. F., and Fletterick, R. J., 1990, Structural and catalytic models of trypsin-like viral proteases, Semin. Virol. 1:311-322.
4. Bonilla, P. J., Gorbalenya, A. E., and Weiss, S. R., 1994, Mouse hepatitis virus strain A59 RNA polymerase gene ORF 1a: heterogeneity among MHV strains, Virology 198:736-740.
5. Bonilla, P. J., Hughes, S. A., Pinon, J. D., and Weiss, S. R., 1995, Characterization of the leader papain-like proteinase of MHV A-59: identification of a new in vitro cleavage site, Virology 209:489-497.
6. Bordier, C., 1981, Phase separation of integral membrane proteins in Triton X-114 solution, J. Biol. Chem. 256:1604-1607.
7. Boyer, J. C. and Haenni, A. L., 1994, Infectious transcripts and cDNA clones of RNA viruses, Virology 198:415-426.
8. Bredenbeek, P. J., and Rice, C. M., 1992, Animal RNA virus expression systems, Semin. Virol. 3:297-310.
9. Breese, S. S., Jr. and McCollum, W. H., 1970, Proceedings of the 2nd International Conference on Equine Infectious Diseases (Bryans, J. T. and Gerber, H. Eds.) S. Karger, Basel. pp.133-139.
10. Brierley, I., 1995, Ribosomal frameshifting on viral RNAs, J. Gen. Virol. 76:1885-1892.
11. Brown, T. D. K., and Brierley, I., 1995, The Coronaviridae (Siddell, S. G. Ed.) Plenum Press, New York. pp. 191-217.
12. Cavanagh, D., 1997, Nidovirales: a new order comprising Coronaviridae and Arteriviridae, Arch. Virol. 142:629-633.
13. Cavanagh, D., Brian, D. A., Brinton, M. A., Enjuanes, L., Holmes, K. V., Horzinek, M. C., Lai, M. M. C., Laude, H., Plagemann, P. G. W., Siddell, S. G., Spaan, W. J. M., Taguchi, F., and Talbot, P. J., 1993, The coronaviridae now comprises two genera, coronavirus and torovirus: report of the coronaviridae study group, Adv. Exp. Med. Biol. 342:255-257.
14. Cavanagh, D., Brian, D. A., Brinton, M. A., Enjuanes, L., Holmes, K. V., Horzinek, M. C., Lai, M. M. C., Laude, H., Plagemann, P. G. W., Siddell, S. G., Spaan, W. J. M., Taguchi, F., and Talbot, P. J., 1994, Revision of the taxonomy of the Coronavirus, Torovirus, and Arterivirus genera, Arch. Virol. 135:227-237.
15. de Groot, R. J., Hardy, W. R., Shirako, Y., and Strauss, J. H., 1990, Cleavage-site preferences of Sindbis virus polyproteins containing the non-structural proteinase. Evidence for temporal regulation of polyprotein processing in vivo, EMBO J. 9:2631-2638.
16. de Vries, A. A. F., Horzinek, M. C., Rottier, P. J. M., and de Groot, R. J., 1997, The genome organization of the Nidovirales: similarities and differences between arteri-, toro-, and coronaviruses, Semin. Virol., in press.
17. den Boon, J. A., Snijder, E. J., Chirnside, E. D., de Vries, A. A. F., Horzinek, M. C., and Spaan, W. J. M., 1991, Equine arteritis virus is not a togavirus but belongs to the coronaviruslike superfamily, J. Virol. 65:2910-2920.
18. den Boon, J. A., Faaberg, K. S., Meulenberg, J. J. M., Wassenaar, A. L. M., Plagemann, P. G. W., Gorbalenya, A. E., and Snijder, E. J., 1995a, Processing and evolution of the N-terminal region of the arterivirus replicase ORF1a protein: identification of two papainlike cysteine proteases, J. Virol. 69:4500-4505.
19. den Boon, J. A., Spaan, W. J. M., and Snijder, E. J., 1995b, Equine arteritis virus subgenomic RNA transcription: UV inactivation and translation inhibition studies, Virology 213:364-372.
20. den Boon, J. A., Kleijnen, M. F., Spaan, W. J. M., and Snijder, E. J, 1996, Equine arteritis virus subgenomic mRNA synthesis: analysis of leader-body junctions and replicative-form RNAs, J. Virol. 70:4291-4298.
21. Dougherty, W. G., and Semler, B. L., 1993, Expression of virus-encoded proteinases: functional and structural similarities with cellular enzymes, Microbiol. Rev. 57:781-822.
22. Fujiki, Y., Hubbard, A. L., Fowler, S., and Lazarow, P. B., 1982, Isolation of intracellular membranes by means of sodium carbonate treatment: application to endoplasmic reticulum, J. Cell Biol. 93:97-102.
23. Gao, H. Q., Schiller, J. J., and Baker, S. C., 1996, Identification of the polymerase polyprotein products p72 and p65 of the murine coronavirus MHV JHM, Virus Res. 45:101-109.
24. Godeny, E. K., Chen, L., Kumar, S. N., Methven, S. L., Koonin, E. V., and Brinton, M. A., 1993, Complete genomic sequence and phylogenetic analysis of the lactate dehydrogenase-elevating virus (LDV), Virology 194:585-596.
25. Gorbalenya, A. E., and Snijder, E. J., 1996, Viral cysteine proteases, Perspect. Drug Discov. Design 6:64-86.
26. Gorbalenya, A. E., Donchenko, A. P., Blinov, V. M., and Koonin, E. V., 1989a, Cysteine proteases of positive strand RNA viruses and chymotrypsin-like serine proteases. A distinct protein superfamily with a common structural fold, FEBS Lett. 243:103-114.
27. Gorbalenya, A. E., Koonin, E. V., Donchenko, A. P., and Blinov, V. M., 1989b, Coronavirus genome: prediction of putative functional domains in the non-structural polyprotein by comparative amino acid sequence analysis, Nucleic Acids Res. 17:4847-4861.
28. Gorbalenya, A. E., Koonin, E. V., and Lai, M. M., 1991, Putative papain-related thiol proteases of positive-strand RNA viruses. Identification of rubi- and aphthovirus proteases and delineation of a novel conserved domain associated with proteases of rubi-, alpha- and coronaviruses, FEBS Lett. 288:201-205.
29. Jacks, T., Madhani, H. D., Masiarz, F. R., and Varmus, H. E., 1988, Signals for ribosomal frameshifting in the Rous sarcoma virus gagpol region, Cell 55:447-458.
30. Jore, J., De Geus, B., Jackson, R. J., Pouwels, P. H., and Enger Valk, B. E., 1988, Poliovirus protein 3CD is the active protease for processing of the precursor protein P1 in vitro, J. Gen. Virol. 69:1627-1636.
31. Lee, H. J., Shieh, C. K., Gorbalenya, A. E., Koonin, E. V., La Monica, N., Tuler, J., Bagdzhadzhyan, A., and Lai, M. M. C., 1991, The complete sequence (22 kilobases) of murine coronavirus gene 1 encoding the putative proteases and RNA polymerase, Virology 180: 567-582.
32. Lemm, J. A., and Rice, C. M., 1993a, Roles of nonstructural polyproteins and cleavage products in regulating Sindbis virus RNA replication and transcription, J. Virol. 67: 1916-1926.
33. Lemm, J. A., and Rice, C. M., 1993b, Assembly of functional Sindbis virus RNA replication complexes: requirement for coexpression of p123 and p34, J. Virol. 67:1905-1915.
34. Lemm, J. A., Rumenapf, T., Strauss, E. G., Strauss, J. H., and Rice, C. M., 1994, Polypeptide requirements for assembly of functional Sindbis virus replication complexes: a model for the temporal regulation of minus-and plus-strand RNA synthesis, EMBO J. 13:2925-2934.
35. Liu, D. X. and Brown, T. D. K., 1995, Characterisation and mutational analysis of an ORF 1a-encoding proteinase domain responsible for proteolytic processing of the infectious bronchitis virus 1a/1b polyprotein, Virology 209:420-427.
36. Lu, Y., Lu, X., and Denison, M. R., 1995, Identification and characterization of a serine-like proteinase of the murine coronavirus MHV-A59, J. Virol. 69:3554-3559.
37. Meulenberg, J. J. M., Hulst, M. M., de Meijer, E. J., Moonen, P. L., den Besten, A., de Kluyver, E. P., Wensvoort, G., and Moormann, R. J. M., 1993, Lelystad virus, the causative agent of porcine epidemic abortion and respiratory syndrome (PEARS), is related to LDV and EAV, Virology 192:62-72.
38. Meulenberg, J. J. M., Bos-de Ruijter, J. N. A., Wensvoort, G., and Moormann, R. J. M., 1997, Infectious transcripts from cloned genome-length cDNA of porcine reproductive respiratory syndrome virus, J. Virol., submitted.
39. Pol, J. M., Wagenaar, F., and Reus, J. E. G., 1997, Comparative morphogenesis of three PRRS virus strains, Vet. Microbiol. 55:203-208.
40. Shirako, Y., and Strauss, J. H., 1994, Regulation of Sindbis virus RNA replication: uncleaved P123 and nsP4 function in minus-strand RNA synthesis, whereas cleaved products from P123 are required for efficient plus-strand RNA synthesis, J. Virol. 68:1874-1885.
41. Snijder, E. J., and Meulenberg, J. J. M., 1998, The molecular biology of arteriviruses, J. Gen. Virol., submitted.
42. Snijder, E. J., and Spaan, W. J. M., 1995, The Coronaviridae (Siddell, S. G. Ed.) Plenum Press, New York. pp. 239-255.
43. Snijder, E. J., den Boon, J. A., Bredenbeek, P. J., Horzinek, M. C., Rijnbrand, R., and Spaan, W. J., 1990, The carboxyl-terminal part of the putative Berne virus polymerase is expressed by ribosomal frameshifting and contains sequence motifs which indicate that toro- and coronaviruses are evolutionarily related, Nucleic Acids Res 18:4535-4542.
44. Snijder, E. J., Wassenaar, A. L. M., and Spaan, W. J. M., 1992, The 5' end of the equine arteritis virus replicase gene encodes a papainlike cysteine protease, J. Virol. 66:7040-7048.
45. Snijder, E. J., Wassenaar, A. L. M., and Spaan, W. J. M., 1994, Proteolytic processing of the replicase ORF1a protein of equine arteritis virus, J. Virol. 68:5755-5764.
46. Snijder, E. J., Wassenaar, A. L. M., Spaan, W. J. M., and Gorbalenya, A. E., 1995, The arterivirus nsp2 protease. an unusual cysteine protease with primary structure similarities to both papain-like and chymotrypsin-like proteases, J. Biol. Chem. 270:16671-16676.
47. Snijder, E. J., Wassenaar, A. L. M., van Dinten, L. C., Spaan, W. J. M., and Gorbalenya, A. E. 1996. The arterivirus nsp4 protease is the prototype of a novel group of chymotrypsin-like enzymes, the 3C-like serine proteases, J. Biol. Chem. 271:4864-4871.
48. Snijder, E. J. and Horzinek, M. C, 1993, Toroviruses: replication, evolution and comparison with other members of the coronavirus-like superfamily, J. Gen. Virol. 74:2305-2316.
49. Stueckemann, J. A., Holth, M., Swart, W. J., Kowalchyk, K., Smith, M. S., Wolstenholme, A. J., Cafruny, W. A., and Plagemann, P. G. W., 1982, Replication of lactate dehydrogenase-elevating virus in macrophages. 2. mechanism of persistent infection in mice and cell culture, J. Gen. Virol. 59:263-272.
50. van Dinten, L. C., Wassenaar, A. L. M., Gorbalenya, A. E., Spaan, W. J. M., and Snijder, E. J., 1996, Processing of the equine arteritis virus replicase ORF1b protein: identification of cleavage products containing the putative viral polymerase and helicase domains, J. Virol. 70:6625-6633.
51. van Dinten, L. C., den Boon, J. A., Wassenaar, A. L. M., Spaan, W. J. M., and Snijder, E. J., 1997, An infectious arterivirus cDNA clone: identification of a replicase point mutation which abolishes discontinuous mRNA transcription, Proc. Natl. Acad. Sci. USA 94:991-996.
52. Wassenaar, A. L. M., Spaan, W. J. M., Gorbalenya, A. E., and Snijder, E. J., 1997, Alternative proteolytic processing of the arterivirus ORF1a polyprotein: evidence that nsp2 acts as a cofactor for the nsp4 serine protease, J. Virol., submitted.
53. Wood, O., Tauraso, N. M., and Liebhaber, H. 1970. Electron microscopic study of tissue cultures infected with simian haemorrhagic fever virus, J. Gen. Virol. 7:129-136.
54. Ypma-Wong, M. F., Dewalt, P. G., Johnson, V. H., Lamb, J. G., and Semler, B. L,. 1988, Protein 3CD is the major poliovirus proteinase responsible for cleavage of the P1 capsid precursor, Virology 166:265-270.
55. Ziebuhr, J., Herold, J., and Siddell, S. G., 1995, Characterization of a human coronavirus (strain 229E) 3C-like proteinase activity, J. Virol. 69:4331-4338.