Dermal penetration and metabolism of p-aminophenol and p-phenylenediamine: Application of the EpiDerm™ human reconstructed epidermis model

Toxicology Letters

Volumn 188, Issue 2, 2009, Pages 119-129

  Hu, Ting ^a   Bailey, Ruth E ^a   Morrall, Stephen W ^a   Aardema, Marilyn J ^a   Stanley, Lesley A ^b   Skare, Julie A ^a  

^a PROCTER AND GAMBLE COMPANY   (United States)

^b Consultant in Investigative Toxicology ^*  (United Kingdom)

Author keywords

Biotransformation; Cytotoxicity; N acetyltransferase 1; p Aminophenol; p Phenylenediamine; Reconstructed epidermis model

Indexed keywords

4 AMINOPHENOL; HAIR DYE; PARACETAMOL; PHENYLENEDIAMINE;

ACETYLATION; ARTICLE; BIOTRANSFORMATION; CULTURE MEDIUM; DRUG METABOLISM; EPIDERMIS; GENOTOXICITY; MODEL; PRIORITY JOURNAL; REPRODUCIBILITY; SKIN PENETRATION; TOXICITY TESTING;

AMINOPHENOLS; BIOTRANSFORMATION; CALIBRATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CONSUMER PRODUCT SAFETY; EPIDERMIS; HAIR DYES; HUMANS; MASS SPECTROMETRY; MODELS, BIOLOGICAL; ORGAN CULTURE TECHNIQUES; PHENYLENEDIAMINES; SKIN ABSORPTION; SOLUTIONS;

EID: 67349233540     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2009.03.019     Document Type: Article

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