Differential expression of organic cation transporters in normal and polyps human nasal epithelium: Implications for in vitro drug delivery studies

International Journal of Pharmaceutics

Volumn 406, Issue 1-2, 2011, Pages 49-54

  Agu, Remigius ^a   MacDonald, Chris ^a   Cowley, Elizabeth ^a   Shao, Di ^a   Renton, Ken ^b   Clarke, David B ^a   Massoud, Emad ^a  

^a DALHOUSIE UNIVERSITY   (Canada)

^b DALHOUSIE UNIVERSITY   (Canada)

Author keywords

Drug delivery; Drug transport; Drug uptake; Nasal epithelium; Organic cation transporters; Polyps; Tissue culture

Indexed keywords

4 DIMETHYLAMINOSTYRYL N METHYLPYRIDINIUM; CATION; ORGANIC CATION CARNITINE TRANSPORTER 1 PROTEIN; ORGANIC CATION CARNITINE TRANSPORTER 2 PROTEIN; ORGANIC CATION TRANSPORTER; ORGANIC CATION TRANSPORTER 1; ORGANIC CATION TRANSPORTER 2; ORGANIC CATION TRANSPORTER 3; RNA; UNCLASSIFIED DRUG;

ARTICLE; CELL CULTURE; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG TRANSPORT; DRUG UPTAKE; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; KRUSKAL WALLIS TEST; NOSE MUCOSA; PH; POLYMERASE CHAIN REACTION; POLYP; PRIORITY JOURNAL; PROTEIN EXPRESSION; TEMPERATURE;

CELL CULTURE TECHNIQUES; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DELIVERY SYSTEMS; FLUORESCENT DYES; GENE EXPRESSION; HUMANS; NASAL MUCOSA; NASAL POLYPS; ORGANIC CATION TRANSPORT PROTEINS; POLYMERASE CHAIN REACTION; PYRIDINIUM COMPOUNDS;

EID: 79951575881     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2010.12.037     Document Type: Article

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