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Volumn 53, Issue 1-3, 1998, Pages 195-203

Nasal delivery of peptides: An in vitro cell culture model for the investigation of transport and metabolism in human nasal epithelium

Author keywords

Cell culture model; Human nasal epithelial cells; Nasal metabolism; Nasal transport; Peptides

Indexed keywords

METENKEPHALIN; PROTIRELIN; RECOMBINANT HUMAN INSULIN;

EID: 0032580451     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(97)00253-8     Document Type: Conference Paper
Times cited : (75)

References (39)
  • 1
    • 0000143406 scopus 로고
    • The clinical use of insulin
    • Woodyatt R.T. The clinical use of insulin. J. Metab. Res. 2:1922;793.
    • (1922) J. Metab. Res. , vol.2 , pp. 793
    • Woodyatt, R.T.1
  • 4
    • 0025153296 scopus 로고
    • Absorption of peptides and proteins from the respiratory tract and the potential of development of locally administered vaccine
    • O'Hagan D.T., Illum L. Absorption of peptides and proteins from the respiratory tract and the potential of development of locally administered vaccine. CRC Crit. Rev. Ther. Drug Carrier Syst. 7:1990;35-97.
    • (1990) CRC Crit. Rev. Ther. Drug Carrier Syst. , vol.7 , pp. 35-97
    • O'Hagan, D.T.1    Illum, L.2
  • 6
    • 0029072298 scopus 로고
    • Direct drug transport from rat nasal cavity to the cerebral fluid: The relation to the molecular weight of drugs
    • Sakane T., Akizuki M., Taki Y., Yamashita S., Sezaki H., Nadai T. Direct drug transport from rat nasal cavity to the cerebral fluid: The relation to the molecular weight of drugs. J. Pharm. Pharmacol. 47:1995;379-381.
    • (1995) J. Pharm. Pharmacol. , vol.47 , pp. 379-381
    • Sakane, T.1    Akizuki, M.2    Taki, Y.3    Yamashita, S.4    Sezaki, H.5    Nadai, T.6
  • 7
    • 0000714450 scopus 로고
    • Nasal route of peptide and protein drug delivery
    • in: V.H.L. Lee (Ed.) Marcel Dekker, New York
    • K.S.E. Su, Nasal route of peptide and protein drug delivery, in: V.H.L. Lee (Ed.), Peptide and Protein Drug Delivery, Marcel Dekker, New York, 1991.
    • (1991) Peptide and Protein Drug Delivery
    • Su, K.S.E.1
  • 9
    • 0025076267 scopus 로고
    • The effect of sodium tauro-24,25-dihydrofusidate on the nasal absorption of human growth hormone in three animal models
    • Baldwin P.A., Klingbeil C.K., Grimm C.C., Longenecker J.P. The effect of sodium tauro-24,25-dihydrofusidate on the nasal absorption of human growth hormone in three animal models. Pharm. Res. 7:1990;547-552.
    • (1990) Pharm. Res. , vol.7 , pp. 547-552
    • Baldwin, P.A.1    Klingbeil, C.K.2    Grimm, C.C.3    Longenecker, J.P.4
  • 10
    • 0002146962 scopus 로고
    • Absorption across the nasal mucosa of animal species: Compounds applied and mechanisms involved
    • A.N. Fisher, Absorption across the nasal mucosa of animal species: Compounds applied and mechanisms involved, Prog. Drug. Metab. (1990) 87-145.
    • (1990) Prog. Drug. Metab. , pp. 87-145
    • Fisher, A.N.1
  • 13
    • 0027420166 scopus 로고
    • In vitro nasal transport across ovine mucosa: Effects of ammonium glycyrrhinate on electrical properties and permeability of growth hormone releasing peptide, mannitol and lucifer yellow
    • Reardon P.M., Gochoco C.H., Audus K.L., Wilson G., Smith P.L. In vitro nasal transport across ovine mucosa: Effects of ammonium glycyrrhinate on electrical properties and permeability of growth hormone releasing peptide, mannitol and lucifer yellow. Pharm. Res. 10:1993;553-561.
    • (1993) Pharm. Res. , vol.10 , pp. 553-561
    • Reardon, P.M.1    Gochoco, C.H.2    Audus, K.L.3    Wilson, G.4    Smith, P.L.5
  • 14
    • 0026540109 scopus 로고
    • The viability of isolated rabbit mucosa in the Ussing chamber, and the permeability of insulin across the membrane
    • Bechgaard E., Gizurarson S., Joergensen L., Larsen R. The viability of isolated rabbit mucosa in the Ussing chamber, and the permeability of insulin across the membrane. Int. J. Pharm. 87:1992;125-132.
    • (1992) Int. J. Pharm. , vol.87 , pp. 125-132
    • Bechgaard, E.1    Gizurarson, S.2    Joergensen, L.3    Larsen, R.4
  • 16
    • 0025102678 scopus 로고
    • The use of cultured epithelial and endothelial cells for drug transport and metabolism studies
    • Audus K.L., Bartel R.L., Hidalgo I.J., Borchardt R.T. The use of cultured epithelial and endothelial cells for drug transport and metabolism studies. Pharm. Res. 7:1990;435-451.
    • (1990) Pharm. Res. , vol.7 , pp. 435-451
    • Audus, K.L.1    Bartel, R.L.2    Hidalgo, I.J.3    Borchardt, R.T.4
  • 17
    • 0025943217 scopus 로고
    • Aminopeptidases of newborn bovine nasal epithelial cell cultures
    • Audus K.L., Tavakoli-Saberi M.R. Aminopeptidases of newborn bovine nasal epithelial cell cultures. Int. J. Pharm. 76:1991;247-255.
    • (1991) Int. J. Pharm. , vol.76 , pp. 247-255
    • Audus, K.L.1    Tavakoli-Saberi, M.R.2
  • 20
    • 0030222269 scopus 로고    scopus 로고
    • The influence of absorption enhancers on intranasal insulin absorption in normal and diabetic subjects
    • Merkus F.W.H.M., Schipper N.G.M., Verhoef J.C. The influence of absorption enhancers on intranasal insulin absorption in normal and diabetic subjects. J. Control. Release. 41:1996;69-75.
    • (1996) J. Control. Release , vol.41 , pp. 69-75
    • Merkus, F.W.H.M.1    Schipper, N.G.M.2    Verhoef, J.C.3
  • 22
    • 0021234456 scopus 로고
    • Structural and functional aspects of cells in the nasal mucociliary system
    • Petruson B., Hansson H.A., Karlsson G. Structural and functional aspects of cells in the nasal mucociliary system. Arch. Otolaryngol. 110:1984;576-581.
    • (1984) Arch. Otolaryngol. , vol.110 , pp. 576-581
    • Petruson, B.1    Hansson, H.A.2    Karlsson, G.3
  • 24
  • 25
    • 0026586445 scopus 로고
    • Drug metabolism in the nasal mucosa
    • Sarkar M.A. Drug metabolism in the nasal mucosa. Pharm. Res. 9:1992;1-9.
    • (1992) Pharm. Res. , vol.9 , pp. 1-9
    • Sarkar, M.A.1
  • 26
    • 0010689810 scopus 로고
    • Routes of administration for polar compounds of moderate molecular weight with particular reference to analogues of somatostatin
    • in: S.S. Davis, L. Illum, E. Tomlinson (Eds.) Plenum Press, New York
    • C.G. Peters, Routes of administration for polar compounds of moderate molecular weight with particular reference to analogues of somatostatin, in: S.S. Davis, L. Illum, E. Tomlinson (Eds.), Delivery Systems for Peptide Drugs, Plenum Press, New York, 1986, pp. 255-263.
    • (1986) Delivery Systems for Peptide Drugs , pp. 255-263
    • Peters, C.G.1
  • 27
    • 0025851808 scopus 로고
    • The nasal mucociliary clearance: Relevance to nasal drug delivery
    • Schipper N.G.M., Verhoef J.C., Merkus F.W.H.M. The nasal mucociliary clearance: Relevance to nasal drug delivery. Pharm. Res. 8:1991;807-814.
    • (1991) Pharm. Res. , vol.8 , pp. 807-814
    • Schipper, N.G.M.1    Verhoef, J.C.2    Merkus, F.W.H.M.3
  • 28
    • 0026651730 scopus 로고
    • Di-iodo-L-tyrosine-labelled dextrans as molecular size markers of nasal absorption in the rat
    • Fisher A.N., Illum L., Davis S.S., Schacht E.H. Di-iodo-L-tyrosine-labelled dextrans as molecular size markers of nasal absorption in the rat. J. Pharm. Pharmacol. 44:1992;550-554.
    • (1992) J. Pharm. Pharmacol. , vol.44 , pp. 550-554
    • Fisher, A.N.1    Illum, L.2    Davis, S.S.3    Schacht, E.H.4
  • 29
    • 0028922915 scopus 로고
    • Development of a human nasal cell culture model and its suitability for transport and metabolism studies under in vitro conditions
    • Werner U., Kissel T. Development of a human nasal cell culture model and its suitability for transport and metabolism studies under in vitro conditions. Pharm. Res. 12:1995;565-571.
    • (1995) Pharm. Res. , vol.12 , pp. 565-571
    • Werner, U.1    Kissel, T.2
  • 30
    • 0029759583 scopus 로고    scopus 로고
    • In-vitro cell culture models of the nasal epithelium: A comparative histochemical investigation of their suitability for drug transport studies
    • Werner U., Kissel T. In-vitro cell culture models of the nasal epithelium: A comparative histochemical investigation of their suitability for drug transport studies. Pharm. Res. 13:1996;978-988.
    • (1996) Pharm. Res. , vol.13 , pp. 978-988
    • Werner, U.1    Kissel, T.2
  • 32
    • 0010646352 scopus 로고
    • Metabolic differences in subclones of a human intestinal cell line (Caco-2): Presystemic cleavage of leu- And met-enkephalin
    • Walter E., Kissel T. Metabolic differences in subclones of a human intestinal cell line (Caco-2): presystemic cleavage of leu- and met-enkephalin. Pharm. Pharmacol. Lett. 3:1994;221-224.
    • (1994) Pharm. Pharmacol. Lett. , vol.3 , pp. 221-224
    • Walter, E.1    Kissel, T.2
  • 33
    • 0028240448 scopus 로고
    • Intranasal permeation of thyrotropin-releasing hormone: In vitro study of permeation and enzymatic degradation
    • Jorgensen L., Beechgaard E. Intranasal permeation of thyrotropin-releasing hormone: in vitro study of permeation and enzymatic degradation. Int. J. Pharm. 107:1994;231-237.
    • (1994) Int. J. Pharm. , vol.107 , pp. 231-237
    • Jorgensen, L.1    Beechgaard, E.2
  • 35
    • 0025040246 scopus 로고
    • Kinetics and pattern of degradation of thyrotropin-releasing hormone in human plasma
    • Moss J., Bundgaard H. Kinetics and pattern of degradation of thyrotropin-releasing hormone in human plasma. Pharm. Res. 7:1990;751-755.
    • (1990) Pharm. Res. , vol.7 , pp. 751-755
    • Moss, J.1    Bundgaard, H.2
  • 36
    • 0025647697 scopus 로고
    • Prodrugs of peptides. 8. In vitro study of intestinal metabolism and penetration of thyrotropin-releasing hormone (TRH) and its prodrugs
    • Moss J., Buur A., Bundgaard H. Prodrugs of peptides. 8. In vitro study of intestinal metabolism and penetration of thyrotropin-releasing hormone (TRH) and its prodrugs. Int. J. Pharm. 66:1990;183-191.
    • (1990) Int. J. Pharm. , vol.66 , pp. 183-191
    • Moss, J.1    Buur, A.2    Bundgaard, H.3
  • 37
    • 0026803221 scopus 로고
    • Nasal absorption of leucine enkephalin in rats and the effects of aminopeptidase inhibition, as determined from percentage of dose unabsorbed
    • Hussain M.A., Aungst B.J. Nasal absorption of leucine enkephalin in rats and the effects of aminopeptidase inhibition, as determined from percentage of dose unabsorbed. Pharm. Res. 9:1992;1362-1364.
    • (1992) Pharm. Res. , vol.9 , pp. 1362-1364
    • Hussain, M.A.1    Aungst, B.J.2
  • 38
    • 0022592643 scopus 로고
    • Aminopeptidase activity in homogenates of various absorptive mucosae in the albino rabbit: Implications in peptide delivery
    • Stratford R.E., Lee V.H.L. Aminopeptidase activity in homogenates of various absorptive mucosae in the albino rabbit: implications in peptide delivery. Int. J. Pharm. 30:1986;73-82.
    • (1986) Int. J. Pharm. , vol.30 , pp. 73-82
    • Stratford, R.E.1    Lee, V.H.L.2
  • 39
    • 0026540109 scopus 로고
    • The viability of isolated rabbit mucosa in the Ussing chamber, and the permeability of insulin across the membrane
    • Bechgaard E., Gizurarson S., Jorgensen L., Larsen R. The viability of isolated rabbit mucosa in the Ussing chamber, and the permeability of insulin across the membrane. Int. J. Pharm. 87:1992;125-132.
    • (1992) Int. J. Pharm. , vol.87 , pp. 125-132
    • Bechgaard, E.1    Gizurarson, S.2    Jorgensen, L.3    Larsen, R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.