-
1
-
-
20444378183
-
Human respiratory epithelial cell culture for drug delivery applications
-
DOI 10.1016/j.ejpb.2005.02.010, PII S0939641105000731
-
B. Forbes, and C. Ehrhardt Human respiratory epithelial cell culture for drug delivery applications Eur J Pharm Biopharm 60 2005 193 205 (Pubitemid 40804561)
-
(2005)
European Journal of Pharmaceutics and Biopharmaceutics
, vol.60
, Issue.2
, pp. 193-205
-
-
Forbes, B.1
Ehrhardt, C.2
-
2
-
-
0036125277
-
Permeability characteristics of Calu-3 human bronchial epithelial cells: In vitro-in vitro correlation to predict lung absorption in rats
-
DOI 10.1080/10611860290007504
-
N.R. Mathias, J. Timoszyk, P.I. Stetsko, J.R. Megill, R.L. Smith, and D.A. Wall Permeability characteristics of calu-3 human bronchial epithelial cells: in vitro-in vivo correlation to predict lung absorption in rats J Drug Target 10 2002 31 40 (Pubitemid 34223847)
-
(2002)
Journal of Drug Targeting
, vol.10
, Issue.1
, pp. 31-40
-
-
Mathias, N.R.1
Timoszyk, J.2
Stetsko, P.I.3
Megill, J.R.4
Smith, R.L.5
Wall, D.A.6
-
3
-
-
0028307695
-
Calu-3: A human airway epithelial cell line that shows cAMP-dependent Cl-secretion
-
B.Q. Shen, W.E. Finkbeiner, J.J. Wine, R.J. Mrsny, and J.H. Widdicombe Calu-3: a human airway epithelial cell line that shows cAMP-dependent Cl-secretion Am J Physiol 266 1994 L493 L501
-
(1994)
Am J Physiol
, vol.266
-
-
Shen, B.Q.1
Finkbeiner, W.E.2
Wine, J.J.3
Mrsny, R.J.4
Widdicombe, J.H.5
-
4
-
-
33745630072
-
Culture of Calu-3 cells at the air interface provides a representative model of the airway epithelial barrier
-
DOI 10.1007/s11095-006-0255-0
-
C.I. Grainger, L.L. Greenwell, D.J. Lockley, G.P. Martin, and B. Forbes Culture of Calu-3 cells at the air interface provides a representative model of the airway epithelial barrier Pharm Res 23 2006 1482 1490 (Pubitemid 43993811)
-
(2006)
Pharmaceutical Research
, vol.23
, Issue.7
, pp. 1482-1490
-
-
Grainger, C.I.1
Greenwell, L.L.2
Lockley, D.J.3
Martin, G.P.4
Forbes, B.5
-
5
-
-
14644421632
-
Development of a size-dependent aerosol deposition model utilising human airway epithelial cells for evaluating aerosol drug delivery
-
D. Cooney, M. Kazantseva, and A.J. Hickey Development of a size-dependent aerosol deposition model utilising human airway epithelial cells for evaluating aerosol drug delivery Altern Lab Anim 32 2004 581 590 (Pubitemid 40321537)
-
(2004)
ATLA Alternatives to Laboratory Animals
, vol.32
, Issue.6
, pp. 581-590
-
-
Cooney, D.1
Kazantseva, M.2
Hickey, A.J.3
-
6
-
-
0036321111
-
Drug absorption by the respiratory mucosa: Cell culture models and particulate drug carriers
-
C. Ehrhardt, J. Fiegel, S. Fuchs, R. Abu-Dahab, U.F. Schaefer, J. Hanes, and C.M. Lehr Drug absorption by the respiratory mucosa: cell culture models and particulate drug carriers J Aerosol Med 15 2002 131 139 (Pubitemid 34827526)
-
(2002)
Journal of Aerosol Medicine: Deposition, Clearance, and Effects in the Lung
, vol.15
, Issue.2
, pp. 131-139
-
-
Ehrhardt, C.1
Fiegel, J.2
Fuchs, S.3
Abu-Dahab, R.4
Schaefer, U.F.5
Hanes, J.6
Lehr, C.-M.7
-
7
-
-
0242584998
-
Large porous particle impingement on lung epithelial cell monolayers - Toward improved particle characterization in the lung
-
DOI 10.1023/A:1023441804464
-
J. Fiegel, C. Ehrhardt, U.F. Schaefer, C.M. Lehr, and J. Hanes Large porous particle impingement on lung epithelial cell monolayers - toward improved particle characterization in the lung Pharm Res 20 2003 788 796 (Pubitemid 36515312)
-
(2003)
Pharmaceutical Research
, vol.20
, Issue.5
, pp. 788-796
-
-
Fiegel, J.1
Ehrhardt, C.2
Schaefer, U.F.3
Lehr, C.-M.4
Hanes, J.5
-
8
-
-
0037458930
-
Drug transport and metabolism characteristics of the human airway epithelial cell line Calu-3
-
DOI 10.1016/S0168-3659(02)00356-5
-
B.I. Florea, M.L. Cassara, H.E. Junginger, and G. Borchard Drug transport and metabolism characteristics of the human airway epithelial cell line Calu-3 J Control Release 87 2003 131 138 (Pubitemid 36255450)
-
(2003)
Journal of Controlled Release
, vol.87
, Issue.1-3
, pp. 131-138
-
-
Florea, B.I.1
Cassara, M.L.2
Junginger, H.E.3
Borchard, G.4
-
9
-
-
0036844744
-
3-treated calu-3 cell monolayers: Modulation of p-glycoprotein activity
-
DOI 10.1023/A:1020761514471
-
J. Patel, D. Pal, V. Vangal, M. Gandhi, and A.L. Mitra Transport of HIV-protease inhibitors across 1 alpha,25di-hydroxy vitamin D3-treated Calu-3 cell monolayers: modulation of P-glycoprotein activity Pharm Res 19 2002 1696 1703 (Pubitemid 35305522)
-
(2002)
Pharmaceutical Research
, vol.19
, Issue.11
, pp. 1696-1703
-
-
Patel, J.1
Pal, D.2
Vangala, V.3
Gandhi, M.4
Mitra, A.K.5
-
10
-
-
0036282607
-
Insulin aggregation and asymmetric transport across human bronchial epithelial cell monolayers (Calu-3)
-
DOI 10.1002/jps.10114
-
I. Pezron, R. Mitra, D. Pal, and A.K. Mitra Insulin aggregation and asymmetric transport across human bronchial epithelial cell monolayers (Calu-3) J Pharm Sci 91 2002 1135 1146 (Pubitemid 34640938)
-
(2002)
Journal of Pharmaceutical Sciences
, vol.91
, Issue.4
, pp. 1135-1146
-
-
Pezron, I.1
Mitra, R.2
Pal, D.3
Mitra, A.K.4
-
11
-
-
85047683608
-
RT-PCR analysis of ABC, SLC and SLCO drug transporters in human lung epithelial cell models
-
S. Endter, D. Francombe, C. Ehrhardt, and M. Gumbleton RT-PCR analysis of ABC, SLC and SLCO drug transporters in human lung epithelial cell models J Pharm Pharmacol 61 2009 583 591
-
(2009)
J Pharm Pharmacol
, vol.61
, pp. 583-591
-
-
Endter, S.1
Francombe, D.2
Ehrhardt, C.3
Gumbleton, M.4
-
12
-
-
43149086651
-
HPEPT1 is responsible for uptake and transport of Gly-Sar in the human bronchial airway epithelial cell-line Calu-3
-
H.B. Sondergaard, B. Brodin, and C.U. Nielsen hPEPT1 is responsible for uptake and transport of Gly-Sar in the human bronchial airway epithelial cell-line Calu-3 Pflugers Arch 456 2008 611 622
-
(2008)
Pflugers Arch
, vol.456
, pp. 611-622
-
-
Sondergaard, H.B.1
Brodin, B.2
Nielsen, C.U.3
-
13
-
-
77951277135
-
Drug transporters in the lung-do they play a role in the biopharmaceutics of inhaled drugs?
-
C. Bosquillon Drug transporters in the lung-do they play a role in the biopharmaceutics of inhaled drugs? J Pharm Sci 99 2009 2240 2255
-
(2009)
J Pharm Sci
, vol.99
, pp. 2240-2255
-
-
Bosquillon, C.1
-
14
-
-
0942279631
-
Epidermal growth factor decreases PEPT2 transport capacity and expression in the rat kidney proximal tubule cell line SKPT0193 cl.2
-
S.A. Bravo, C.U. Nielsen, J. Amstrup, S. Frokjaer, and B. Brodin Epidermal growth factor decreases PEPT2 transport capacity and expression in the rat kidney proximal tubule cell line SKPT0193 cl.2 Am J Physiol Renal Physiol 286 2004 F385 F393
-
(2004)
Am J Physiol Renal Physiol
, vol.286
-
-
Bravo, S.A.1
Nielsen, C.U.2
Amstrup, J.3
Frokjaer, S.4
Brodin, B.5
-
15
-
-
70350337094
-
Intestinal gaboxadol absorption via PAT1(SLC36A1): Modified absorption in vivo following co-administration of l-tryptophan
-
M. Larsen, R. Holm, K.G. Jensen, B. Brodin, and C.U. Nielsen Intestinal gaboxadol absorption via PAT1(SLC36A1): modified absorption in vivo following co-administration of l-tryptophan. Br J Pharmacol 157 2009 1380 1389
-
(2009)
Br J Pharmacol
, vol.157
, pp. 1380-1389
-
-
Larsen, M.1
Holm, R.2
Jensen, K.G.3
Brodin, B.4
Nielsen, C.U.5
-
16
-
-
73749084701
-
5-Hydroxy-l-tryptophan alters gaboxadol pharmacokinetics in rats: Involvement of PAT1 and rOat1 in gaboxadol absorption and elimination
-
M. Larsen, R. Holm, K.G. Jensen, C. Sveigaard, B. Brodin, and C.U. Nielsen 5-Hydroxy-l-tryptophan alters gaboxadol pharmacokinetics in rats: Involvement of PAT1 and rOat1 in gaboxadol absorption and elimination Eur J Pharm Sci 39 2010 68 75
-
(2010)
Eur J Pharm Sci
, vol.39
, pp. 68-75
-
-
Larsen, M.1
Holm, R.2
Jensen, K.G.3
Sveigaard, C.4
Brodin, B.5
Nielsen, C.U.6
-
17
-
-
0034605705
-
Characterization of the Calu-3 cell line as a tool to screen pulmonary drug delivery
-
K.A. Foster, M.L. Avery, M. Yazdanian, and K.L. Audus Characterization of the Calu-3 cell line as a tool to screen pulmonary drug delivery Int J Pharm 208 2000 1 11
-
(2000)
Int J Pharm
, vol.208
, pp. 1-11
-
-
Foster, K.A.1
Avery, M.L.2
Yazdanian, M.3
Audus, K.L.4
-
18
-
-
0030940316
-
Vectorial transcytosis of dimeric IgA by the Calu-3 human lung epithelial cell line: Upregulation by IFN-gamma
-
S. Loman, J. Radl, H.M. Jansen, T.A. Out, and R. Lutter Vectorial transcytosis of dimeric IgA by the Calu-3 human lung epithelial cell line: upregulation by IFN-gamma Am J Physiol 272 1997 L951 L958
-
(1997)
Am J Physiol
, vol.272
-
-
Loman, S.1
Radl, J.2
Jansen, H.M.3
Out, T.A.4
Lutter, R.5
-
19
-
-
16444373706
-
Functional characterization of the peptide transporter PEPT2 in primary cultures of human upper airway epithelium
-
DOI 10.1165/rcmb.2004-0322OC
-
P.M. Bahadduri, V.M. D'Souza, J.K. Pinsonneault, W. Sadee, S. Bao, D.L. Knoell, and P.W. Swaan Functional characterization of the peptide transporter PEPT2 in primary cultures of human upper airway epithelium Am J Respir Cell Mol Biol 32 2005 319 325 (Pubitemid 40478307)
-
(2005)
American Journal of Respiratory Cell and Molecular Biology
, vol.32
, Issue.4
, pp. 319-325
-
-
Bahadduri, P.M.1
D'Souza, V.M.2
Pinsonneault, J.K.3
Sadee, W.4
Bao, S.5
Knoell, D.L.6
Swaan, P.W.7
-
20
-
-
0028207584
-
+ co-transport system in the Caco-2 human colon carcinoma cell line
-
M. Brandsch, Y. Miyamoto, V. Ganapathy, and F.H. Leibach Expression and protein kinase C-dependent regulation of peptide/H+ co- transport system in the Caco-2 human colon carcinoma cell line Biochem J 299 Pt 1 1994 253 260 (Pubitemid 24106317)
-
(1994)
Biochemical Journal
, vol.299
, Issue.1
, pp. 253-260
-
-
Brandsch, M.1
Miyamoto, Y.2
Ganapathy, V.3
Leibach, F.H.4
-
21
-
-
0037495276
-
Epidermal growth factor and insulin short-term increase hPepT1-mediated glycylsarcosine uptake in Caco-2 cells
-
DOI 10.1046/j.1365-201X.2003.01113.x
-
C.U. Nielsen, J. Amstrup, B. Steffansen, S. Frokjaer, and B. Brodin Epidermal growth factor and insulin short-term increase hPepT1-mediated glycylsarcosine uptake in Caco-2 cells Acta Physiol Scand 178 2003 139 148 (Pubitemid 36718165)
-
(2003)
Acta Physiologica Scandinavica
, vol.178
, Issue.2
, pp. 139-148
-
-
Nielsen, C.U.1
Amstrup, J.2
Nielsen, R.3
Steffansen, B.4
Frokjaer, S.5
Brodin, B.6
-
22
-
-
23844467052
-
Characterization of rPEPT2-mediated Gly-Sar transport parameters in the rat kidney proximal tubule cell line SKPT-0193 cl.2 cultured in basic growth media
-
DOI 10.1021/mp049892q
-
S.A. Bravo, C.U. Nielsen, S. Frokjaer, and B. Brodin Characterization of rPEPT2-mediated Gly-Sar transport parameters in the rat kidney proximal tubule cell line SKPT-0193 cl.2 cultured in basic growth media Mol Pharm 2 2005 98 108 (Pubitemid 41295357)
-
(2005)
Molecular Pharmaceutics
, vol.2
, Issue.2
, pp. 98-108
-
-
Bravo, S.A.1
Nielsen, C.U.2
Frokjaer, S.3
Brodin, B.4
-
23
-
-
0033407050
-
Expression of multidrug resistance protein-3 (multispecific organic anion transporter-D) in human embryonic kidney 293 cells confers resistance to anticancer agents
-
H. Zeng, L.J. Bain, M.G. Belinsky, and G.D. Kruh Expression of multidrug resistance protein-3 (multispecific organic anion transporter-D) in human embryonic kidney 293 cells confers resistance to anticancer agents Cancer Res 59 1999 5964 5967 (Pubitemid 30004958)
-
(1999)
Cancer Research
, vol.59
, Issue.23
, pp. 5964-5967
-
-
Zeng, H.1
Bain, L.J.2
Belinsky, M.G.3
Kruh, G.D.4
-
24
-
-
0030858837
-
61 position in predicted transmembrane domain 1 of human MDR1/P-Glycoprotein
-
DOI 10.1021/bi970553v
-
Y. Taguchi, K. Kino, M. Morishima, T. Komano, S.E. Kane, and K. Ueda Alteration of substrate specificity by mutations at the His61 position in predicted transmembrane domain 1 of human MDR1/P-glycoprotein Biochemistry 36 1997 8883 8889 (Pubitemid 27342534)
-
(1997)
Biochemistry
, vol.36
, Issue.29
, pp. 8883-8889
-
-
Taguchi, Y.1
Kino, K.2
Morishima, M.3
Komano, T.4
Kane, S.E.5
Ueda, K.6
-
25
-
-
23244451963
-
MRP2 (ABCC2) transports taxanes and confers paclitaxel resistance and both processes are stimulated by probenecid
-
DOI 10.1002/ijc.21013
-
M.T. Huisman, A.A. Chhatta, T.O. van, J.H. Beijnen, and A.H. Schinkel MRP2 (ABCC2) transports taxanes and confers paclitaxel resistance and both processes are stimulated by probenecid Int J Cancer 116 2005 824 829 (Pubitemid 41099717)
-
(2005)
International Journal of Cancer
, vol.116
, Issue.5
, pp. 824-829
-
-
Huisman, M.T.1
Chhatta, A.A.2
Van Tellingen, O.3
Beijnen, J.H.4
Schinkel, A.H.5
-
26
-
-
0041344702
-
Functional complementation between a novel mammalian polygenic transport complex and an evolutionarily ancient organic solute transporter, OSTα-OSTβ
-
DOI 10.1074/jbc.M301106200
-
D.J. Seward, A.S. Koh, J.L. Boyer, and N. Ballatori Functional complementation between a novel mammalian polygenic transport complex and an evolutionarily ancient organic solute transporter, OSTalpha-OSTbeta J Biol Chem 278 2003 27473 27482 (Pubitemid 36899930)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.30
, pp. 27473-27482
-
-
Seward, D.J.1
Koh, A.S.2
Boyer, J.L.3
Ballatori, N.4
-
27
-
-
48749087514
-
Bile acid transporters in health and disease
-
A. Kosters, and S.J. Karpen Bile acid transporters in health and disease Xenobiotica 38 2008 1043 1071
-
(2008)
Xenobiotica
, vol.38
, pp. 1043-1071
-
-
Kosters, A.1
Karpen, S.J.2
-
28
-
-
38349170961
-
Amino acid transport across mammalian intestinal and renal epithelia
-
S. Broer Amino acid transport across mammalian intestinal and renal epithelia Physiol Rev 88 2008 249 286
-
(2008)
Physiol Rev
, vol.88
, pp. 249-286
-
-
Broer, S.1
-
29
-
-
67349227126
-
Impact of carriers in oral absorption: Permeation across Caco-2 cells for the organic anions estrone-3-sulfate and glipizide
-
L.K. Gram, G.M. Rist, H. Lennernas, and B. Steffansen Impact of carriers in oral absorption: permeation across Caco-2 cells for the organic anions estrone-3-sulfate and glipizide Eur J Pharm Sci 37 2009 378 386
-
(2009)
Eur J Pharm Sci
, vol.37
, pp. 378-386
-
-
Gram, L.K.1
Rist, G.M.2
Lennernas, H.3
Steffansen, B.4
-
30
-
-
0042856460
-
Breast cancer resistance protein exports sulfated estrogens but not free estrogens
-
DOI 10.1124/mol.64.3.610
-
Y. Imai, S. Asada, S. Tsukahara, E. Ishikawa, T. Tsuruo, and Y. Sugimoto Breast cancer resistance protein exports sulfated estrogens but not free estrogens Mol Pharmacol 64 2003 610 618 (Pubitemid 37048564)
-
(2003)
Molecular Pharmacology
, vol.64
, Issue.3
, pp. 610-618
-
-
Imai, Y.1
Asada, S.2
Tsukahara, S.3
Ishikawa, E.4
Tsuruo, T.5
Sugimoto, Y.6
-
31
-
-
0038265441
-
ABCG2 transports sulfated conjugates of steroids and xenobiotics
-
DOI 10.1074/jbc.M212399200
-
M. Suzuki, H. Suzuki, Y. Sugimoto, and Y. Sugiyama ABCG2 transports sulfated conjugates of steroids and xenobiotics J Biol Chem 278 2003 22644 22649 (Pubitemid 36830322)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.25
, pp. 22644-22649
-
-
Suzuki, M.1
Suzuki, H.2
Sugimoto, Y.3
Sugiyama, Y.4
-
32
-
-
33746048844
-
Predominant contribution of organic anion transporting polypeptide OATP-B (OATP2B1) to apical uptake of estrone-3-sulfate by human intestinal Caco-2 cells
-
DOI 10.1124/dmd.106.009530
-
Y. Sai, Y. Kaneko, S. Ito, K. Mitsuoka, Y. Kato, I. Tamai, P. Artursson, and A. Tsuji Predominant contribution of organic anion transporting polypeptide OATP-B (OATP2B1) to apical uptake of estrone-3-sulfate by human intestinal Caco-2 cells Drug Metab Dispos 34 2006 1423 1431 (Pubitemid 44079886)
-
(2006)
Drug Metabolism and Disposition
, vol.34
, Issue.8
, pp. 1423-1431
-
-
Sai, Y.1
Kaneko, Y.2
Ito, S.3
Mitsuoka, K.4
Kato, Y.5
Tamai, I.6
Artursson, P.7
Tsuji, A.8
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