RPMI 2650 epithelial model and three-dimensional reconstructed human nasal mucosa as in vitro models for nasal permeation studies

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 74, Issue 2, 2010, Pages 290-297

  Wengst, Annette ^a   Reichl, Stephan ^a  

^a TECHNICAL UNIVERSITY OF BRAUNSCHWEIG   (Germany)

Author keywords

Air liquid interface; Coculture; Drug permeation; Human nasal fibroblasts; Nasal mucosa; Paracellular permeation; RPMI 2650; Transcellular permeation; Transepithelial electrical resistance

Indexed keywords

COLLAGEN; FLUORESCEIN ISOTHIOCYANATE DEXTRAN; FLUORESCEIN SODIUM; PROPRANOLOL;

ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; CULTURE MEDIUM; DRUG PENETRATION; ELECTRIC RESISTANCE; EPITHELIUM CELL; FIBROBLAST; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; MICROSCOPY; NONHUMAN; NORMAL HUMAN; NOSE MUCOSA; PASSIVE TRANSPORT; PERMEABILITY BARRIER; RAT; RPMI 2650 CELL;

CELL LINE, TUMOR; CELL MEMBRANE PERMEABILITY; COCULTURE TECHNIQUES; DEXTRANS; ELECTRIC IMPEDANCE; FIBROBLASTS; FLUORESCEIN; FLUORESCEIN-5-ISOTHIOCYANATE; HUMANS; MODELS, ANATOMIC; MODELS, BIOLOGICAL; NASAL MUCOSA; PROPRANOLOL;

EID: 75449084946     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2009.08.008     Document Type: Article

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