-
1
-
-
0038721687
-
Mechanisms of sodium channel inactivation
-
Goldin AL (2003) Mechanisms of sodium channel inactivation. Curr Opin Neurobiol 13:284-290
-
(2003)
Curr Opin Neurobiol
, vol.13
, pp. 284-290
-
-
Goldin, A.L.1
-
2
-
-
25444498065
-
Sodium channel inactivation: Molecular determinants and modulation
-
Ulbricht W (2005) Sodium channel inactivation: molecular determinants and modulation. Physiol Rev 85:1271-1301
-
(2005)
Physiol Rev
, vol.85
, pp. 1271-1301
-
-
Ulbricht, W.1
-
3
-
-
0037264170
-
Overview of the voltage-gated sodium channel family
-
Yu FH, Catterall WA (2003) Overview of the voltage-gated sodium channel family. Genome Biol 4:207
-
(2003)
Genome Biol
, vol.4
, pp. 207
-
-
Yu, F.H.1
Catterall, W.A.2
-
4
-
-
76349097096
-
Molecular determinants of coupling between the domain III voltage sensor and pore of a sodium channel
-
Muroi Y, Arcisio-Miranda M, Chowdhury S, Chanda B (2010) Molecular determinants of coupling between the domain III voltage sensor and pore of a sodium channel. Nat Struct Mol Biol 17:230-237
-
(2010)
Nat Struct Mol Biol
, vol.17
, pp. 230-237
-
-
Muroi, Y.1
Arcisio-Miranda, M.2
Chowdhury, S.3
Chanda, B.4
-
5
-
-
79960621367
-
The crystal structure of a voltage-gated sodium channel
-
Payandeh J, Scheuer T, Zheng N, Catterall WA (2011) The crystal structure of a voltage-gated sodium channel. Nature 475:353-358
-
(2011)
Nature
, vol.475
, pp. 353-358
-
-
Payandeh, J.1
Scheuer, T.2
Zheng, N.3
Catterall, W.A.4
-
6
-
-
22544439334
-
Ion permeation through a voltage-sensitive gating pore in brain sodium channels having voltage sensor mutations
-
Sokolov S, Scheuer T, Catterall WA (2005) Ion permeation through a voltage-sensitive gating pore in brain sodium channels having voltage sensor mutations. Neuron 47:183-189
-
(2005)
Neuron
, vol.47
, pp. 183-189
-
-
Sokolov, S.1
Scheuer, T.2
Catterall, W.A.3
-
7
-
-
0017743723
-
Inactivation of the sodium channel. II. Gating current experiments
-
Armstrong CM, Bezanilla F (1977) Inactivation of the sodium channel. II. Gating current experiments. J Gen Physiol 70:567-590
-
(1977)
J Gen Physiol
, vol.70
, pp. 567-590
-
-
Armstrong, C.M.1
Bezanilla, F.2
-
8
-
-
0015359032
-
Inactivation of the sodium current in Myxicola giant axons. Evidence for coupling to the activation process
-
Goldman L, Schauf CL (1972) Inactivation of the sodium current in Myxicola giant axons. Evidence for coupling to the activation process. J Gen Physiol 59:659-675
-
(1972)
J Gen Physiol
, vol.59
, pp. 659-675
-
-
Goldman, L.1
Schauf, C.L.2
-
9
-
-
0021086246
-
A reinterpretation of mammalian sodium channel gating based on single channel recording
-
Aldrich RW, Corey DP, Stevens CF (1983) A reinterpretation of mammalian sodium channel gating based on single channel recording. Nature 306:436-441
-
(1983)
Nature
, vol.306
, pp. 436-441
-
-
Aldrich, R.W.1
Corey, D.P.2
Stevens, C.F.3
-
10
-
-
0023156585
-
Voltage-dependent gating of single sodium channels from mammalian neuroblastoma cells
-
Aldrich RW, Stevens CF (1987) Voltage-dependent gating of single sodium channels from mammalian neuroblastoma cells. J Neurosci 7:418-431
-
(1987)
J Neurosci
, vol.7
, pp. 418-431
-
-
Aldrich, R.W.1
Stevens, C.F.2
-
11
-
-
0028258554
-
Na+ channels must deactivate to recover from inactivation
-
Kuo CC, Bean BP (1994) Na+ channels must deactivate to recover from inactivation. Neuron 12:819-829
-
(1994)
Neuron
, vol.12
, pp. 819-829
-
-
Kuo, C.C.1
Bean, B.P.2
-
12
-
-
0015902531
-
Destruction of sodium conductance inactivation in squid axons perfused with pronase
-
Armstrong CM, Bezanilla F, Rojas E (1973) Destruction of sodium conductance inactivation in squid axons perfused with pronase. J Gen Physiol 62:375-391
-
(1973)
J Gen Physiol
, vol.62
, pp. 375-391
-
-
Armstrong, C.M.1
Bezanilla, F.2
Rojas, E.3
-
13
-
-
0023784649
-
Identification of an intracellular peptide segment involved in sodium channel inactivation
-
Vassilev P, Scheuer T, Catterall WA (1988) Identification of an intracellular peptide segment involved in sodium channel inactivation. Science 241:1658-1661
-
(1988)
Science
, vol.241
, pp. 1658-1661
-
-
Vassilev, P.1
Scheuer, T.2
Catterall, W.A.3
-
14
-
-
0026483172
-
A cluster of hydrophobic amino acid residues required for fast Na+ channel inactivation
-
West JW, Patton DE, Scheuer T, Wang Y, Goldin AL, Catterall WA (1992) A cluster of hydrophobic amino acid residues required for fast Na+ channel inactivation. Proc Natl Acad Sci USA 89:10905-10909
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 10905-10909
-
-
West, J.W.1
Patton, D.E.2
Scheuer, T.3
Wang, Y.4
Goldin, A.L.5
Catterall, W.A.6
-
15
-
-
0035141321
-
Inactivation and recovery of sodium currents in cerebellar Purkinje neurons: Evidence for two mechanisms
-
Raman IM, Bean BP (2001) Inactivation and recovery of sodium currents in cerebellar Purkinje neurons: evidence for two mechanisms. Biophys J 80:729-737
-
(2001)
Biophys J
, vol.80
, pp. 729-737
-
-
Raman, I.M.1
Bean, B.P.2
-
16
-
-
33751108977
-
Impaired inactivation gate stabilization predicts increased persistent current for an epilepsy-associated SCN1A mutation
-
Kahlig KM, Misra SN, George AL Jr (2006) Impaired inactivation gate stabilization predicts increased persistent current for an epilepsy-associated SCN1A mutation. J Neurosci 26:10958-10966
-
(2006)
J Neurosci
, vol.26
, pp. 10958-10966
-
-
Kahlig, K.M.1
Misra, S.N.2
George Jr., A.L.3
-
17
-
-
0028326016
-
Sodium channel mutations in paramyotonia congenita uncouple inactivation from activation
-
Chahine M, George AL Jr, Zhou M, Ji S, Sun W, Barchi RL, Horn R (1994) Sodium channel mutations in paramyotonia congenita uncouple inactivation from activation. Neuron 12:281-294
-
(1994)
Neuron
, vol.12
, pp. 281-294
-
-
Chahine, M.1
George Jr., A.L.2
Zhou, M.3
Ji, S.4
Sun, W.5
Barchi, R.L.6
Horn, R.7
-
18
-
-
0032805568
-
The Na channel voltage sensor associated with inactivation is localized to the external charged residues of domain IV, S4
-
Sheets MF, Kyle JW, Kallen RG, Hanck DA (1999) The Na channel voltage sensor associated with inactivation is localized to the external charged residues of domain IV, S4. Biophys J 77:747-757
-
(1999)
Biophys J
, vol.77
, pp. 747-757
-
-
Sheets, M.F.1
Kyle, J.W.2
Kallen, R.G.3
Hanck, D.A.4
-
19
-
-
0039552118
-
Solution structure of the sodium channel inactivation gate
-
Rohl CA, Boeckman FA, Baker C, Scheuer T, Catterall WA, Klevit RE (1999) Solution structure of the sodium channel inactivation gate. Biochemistry 38:855-861
-
(1999)
Biochemistry
, vol.38
, pp. 855-861
-
-
Rohl, C.A.1
Boeckman, F.A.2
Baker, C.3
Scheuer, T.4
Catterall, W.A.5
Klevit, R.E.6
-
20
-
-
0033831716
-
Structural study of the sodium channel inactivation gate peptide including an isoleucinephenylalanine-methionine motif and its analogous peptide (phenylalanine/glutamine) in trifluoroethanol solutions and SDS micelles
-
Kuroda Y, Miyamoto K, Matsumoto M, Maeda Y, Kanaori K, Otaka A, Fujii N, Nakagawa T (2000) Structural study of the sodium channel inactivation gate peptide including an isoleucinephenylalanine-methionine motif and its analogous peptide (phenylalanine/glutamine) in trifluoroethanol solutions and SDS micelles. J Pept Res 56:172-184
-
(2000)
J Pept Res
, vol.56
, pp. 172-184
-
-
Kuroda, Y.1
Miyamoto, K.2
Matsumoto, M.3
Maeda, Y.4
Kanaori, K.5
Otaka, A.6
Fujii, N.7
Nakagawa, T.8
-
21
-
-
0035888115
-
Solution structure of the cytoplasmic linker between domain III-S6 and domain IV-S1 (III-IV linker) of the rat brain sodium channel in SDS micelles
-
Miyamoto K, Nakagawa T, Kuroda Y (2001) Solution structure of the cytoplasmic linker between domain III-S6 and domain IV-S1 (III-IV linker) of the rat brain sodium channel in SDS micelles. Biopolymers 59:380-393
-
(2001)
Biopolymers
, vol.59
, pp. 380-393
-
-
Miyamoto, K.1
Nakagawa, T.2
Kuroda, Y.3
-
22
-
-
0028363484
-
Restoration of inactivation and block of open sodium channels by an inactivation gate peptide
-
Eaholtz G, Scheuer T, Catterall WA (1994) Restoration of inactivation and block of open sodium channels by an inactivation gate peptide. Neuron 12:1041-1048
-
(1994)
Neuron
, vol.12
, pp. 1041-1048
-
-
Eaholtz, G.1
Scheuer, T.2
Catterall, W.A.3
-
23
-
-
0031931679
-
Kinetic analysis of block of open sodium channels by a peptide containing the isoleucine, phenylalanine, and methionine (IFM) motif from the inactivation gate
-
Eaholtz G, Zagotta WN, Catterall WA (1998) Kinetic analysis of block of open sodium channels by a peptide containing the isoleucine, phenylalanine, and methionine (IFM) motif from the inactivation gate. J Gen Physiol 111:75-82
-
(1998)
J Gen Physiol
, vol.111
, pp. 75-82
-
-
Eaholtz, G.1
Zagotta, W.N.2
Catterall, W.A.3
-
24
-
-
0033166236
-
A human muscle Na+ channel mutation in the voltage sensor IV/S4 affects channel block by the pentapeptide KIFMK
-
Peter W, Mitrovic N, Schiebe M, Lehmann-Horn F, Lerche H (1999) A human muscle Na+ channel mutation in the voltage sensor IV/S4 affects channel block by the pentapeptide KIFMK. J Physiol 518(Pt 1):13-22
-
(1999)
J Physiol
, vol.518
, Issue.PART 1
, pp. 13-22
-
-
Peter, W.1
Mitrovic, N.2
Schiebe, M.3
Lehmann-Horn, F.4
Lerche, H.5
-
25
-
-
14644394306
-
Block of inactivation-deficient cardiac Na(+) channels by acetyl-KIFMK-amide
-
Wang SY, Wang GK (2005) Block of inactivation-deficient cardiac Na(+) channels by acetyl-KIFMK-amide. Biochem Biophys Res Commun 329:780-788
-
(2005)
Biochem Biophys Res Commun
, vol.329
, pp. 780-788
-
-
Wang, S.Y.1
Wang, G.K.2
-
26
-
-
20844446135
-
A novel epilepsy mutation in the sodium channel SCN1A identifies a cytoplasmic domain for beta subunit interaction
-
Spampanato J, Kearney JA, de Haan G, McEwen DP, Escayg A, Aradi I, MacDonald BT, Levin SI, Soltesz I, Benna P, Montalenti E, Isom LL, Goldin AL, Meisler MH (2004) A novel epilepsy mutation in the sodium channel SCN1A identifies a cytoplasmic domain for beta subunit interaction. J Neurosci 24:10022-10034
-
(2004)
J Neurosci
, vol.24
, pp. 10022-10034
-
-
Spampanato, J.1
Kearney, J.A.2
De Haan, G.3
McEwen, D.P.4
Escayg, A.5
Aradi, I.6
MacDonald, B.T.7
Levin, S.I.8
Soltesz, I.9
Benna, P.10
Montalenti, E.11
Isom, L.L.12
Goldin, A.L.13
Meisler, M.H.14
-
27
-
-
29244448307
-
Sodium channel dysfunction in intractable childhood epilepsy with generalized tonic-clonic seizures
-
Rhodes TH, Vanoye CG, Ohmori I, Ogiwara I, Yamakawa K, George AL Jr (2005) Sodium channel dysfunction in intractable childhood epilepsy with generalized tonic-clonic seizures. J Physiol 569:433-445
-
(2005)
J Physiol
, vol.569
, pp. 433-445
-
-
Rhodes, T.H.1
Vanoye, C.G.2
Ohmori, I.3
Ogiwara, I.4
Yamakawa, K.5
George Jr., A.L.6
-
28
-
-
21044459236
-
A C-terminal skeletal muscle sodium channel mutation associated with myotonia disrupts fast inactivation
-
Wu FF, Gordon E, Hoffman EP, Cannon SC (2005) A C-terminal skeletal muscle sodium channel mutation associated with myotonia disrupts fast inactivation. J Physiol 565:371-380
-
(2005)
J Physiol
, vol.565
, pp. 371-380
-
-
Wu, F.F.1
Gordon, E.2
Hoffman, E.P.3
Cannon, S.C.4
-
29
-
-
0032572594
-
Novel LQT-3 mutation affects Na+ channel activity through interactions between alpha-and beta1-subunits
-
An RH, Wang XL, Kerem B, Benhorin J, Medina A, Goldmit M, Kass RS (1998) Novel LQT-3 mutation affects Na+ channel activity through interactions between alpha-and beta1-subunits. Circ Res 83:141-146
-
(1998)
Circ Res
, vol.83
, pp. 141-146
-
-
An, R.H.1
Wang, X.L.2
Kerem, B.3
Benhorin, J.4
Medina, A.5
Goldmit, M.6
Kass, R.S.7
-
30
-
-
1542375174
-
Structural effects of an LQT-3 mutation on heart Na+ channel gating
-
Tateyama M, Liu H, Yang AS, Cormier JW, Kass RS (2004) Structural effects of an LQT-3 mutation on heart Na+ channel gating. Biophys J 86:1843-1851
-
(2004)
Biophys J
, vol.86
, pp. 1843-1851
-
-
Tateyama, M.1
Liu, H.2
Yang, A.S.3
Cormier, J.W.4
Kass, R.S.5
-
31
-
-
0035910013
-
Role of the C-terminal domain in inactivation of brain and cardiac sodium channels
-
Mantegazza M, Yu FH, Catterall WA, Scheuer T (2001) Role of the C-terminal domain in inactivation of brain and cardiac sodium channels. Proc Natl Acad Sci USA 98:15348-15353
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 15348-15353
-
-
Mantegazza, M.1
Yu, F.H.2
Catterall, W.A.3
Scheuer, T.4
-
32
-
-
0842326191
-
The Na+ channel inactivation gate is a molecular complex: A novel role of the COOH-terminal domain
-
Motoike HK, Liu H, Glaaser IW, Yang AS, Tateyama M, Kass RS (2004) The Na+ channel inactivation gate is a molecular complex: a novel role of the COOH-terminal domain. J Gen Physiol 123:155-165
-
(2004)
J Gen Physiol
, vol.123
, pp. 155-165
-
-
Motoike, H.K.1
Liu, H.2
Glaaser, I.W.3
Yang, A.S.4
Tateyama, M.5
Kass, R.S.6
-
33
-
-
0030855929
-
Interaction between the sodium channel inactivation linker and domain III S4-S5
-
Smith MR, Goldin AL (1997) Interaction between the sodium channel inactivation linker and domain III S4-S5. Biophys J 73:1885-1895
-
(1997)
Biophys J
, vol.73
, pp. 1885-1895
-
-
Smith, M.R.1
Goldin, A.L.2
-
34
-
-
0035378502
-
Fibroblast growth factor homologous factor 1B binds to the C terminus of the tetrodotoxin-resistant sodium channel rNav1.9a (NaN)
-
Liu C, Dib-Hajj SD, Waxman SG (2001) Fibroblast growth factor homologous factor 1B binds to the C terminus of the tetrodotoxin-resistant sodium channel rNav1.9a (NaN). J Biol Chem 276:18925-18933
-
(2001)
J Biol Chem
, vol.276
, pp. 18925-18933
-
-
Liu, C.1
Dib-Hajj, S.D.2
Waxman, S.G.3
-
35
-
-
0037428518
-
Modulation of the cardiac sodium channel Nav1.5 by fibroblast growth factor homologous factor 1B
-
Liu CJ, Dib-Hajj SD, Renganathan M, Cummins TR, Waxman SG (2003) Modulation of the cardiac sodium channel Nav1.5 by fibroblast growth factor homologous factor 1B. J Biol Chem 278:1029-1036
-
(2003)
J Biol Chem
, vol.278
, pp. 1029-1036
-
-
Liu, C.J.1
Dib-Hajj, S.D.2
Renganathan, M.3
Cummins, T.R.4
Waxman, S.G.5
-
36
-
-
0035107612
-
The intracellular segment of the sodium channel beta 1 subunit is required for its efficient association with the channel alpha subunit
-
Meadows L, Malhotra JD, Stetzer A, Isom LL, Ragsdale DS (2001) The intracellular segment of the sodium channel beta 1 subunit is required for its efficient association with the channel alpha subunit. J Neurochem 76:1871-1878
-
(2001)
J Neurochem
, vol.76
, pp. 1871-1878
-
-
Meadows, L.1
Malhotra, J.D.2
Stetzer, A.3
Isom, L.L.4
Ragsdale, D.S.5
-
37
-
-
0027764469
-
Modulation of the skeletal muscle sodium channel alpha-subunit by the beta 1-subunit
-
Wallner M, Weigl L, Meera P, Lotan I (1993) Modulation of the skeletal muscle sodium channel alpha-subunit by the beta 1-subunit. FEBS Lett 336:535-539
-
(1993)
FEBS Lett
, vol.336
, pp. 535-539
-
-
Wallner, M.1
Weigl, L.2
Meera, P.3
Lotan, I.4
-
38
-
-
0035887890
-
Gating properties of Na(v)1.7 and Na(v)1.8 peripheral nerve sodium channels
-
Vijayaragavan K, OLeary ME, Chahine M (2001) Gating properties of Na(v)1.7 and Na(v)1.8 peripheral nerve sodium channels. J Neurosci 21:7909-7918
-
(2001)
J Neurosci
, vol.21
, pp. 7909-7918
-
-
Vijayaragavan, K.1
Oleary, M.E.2
Chahine, M.3
-
39
-
-
80051488896
-
Regulation of Nav1.6 and Nav1.8 peripheral nerve sodium channels by auxiliary {beta} subunits
-
Zhao J, OLeary ME, Chahine M (2011) Regulation of Nav1.6 and Nav1.8 peripheral nerve sodium channels by auxiliary {beta} subunits. J Neurophysiol
-
J Neurophysiol
, vol.2011
-
-
Zhao, J.1
Oleary, M.E.2
Chahine, M.3
-
40
-
-
3342991643
-
Fibroblast growth factor homologous factor 2B: Association with Nav1.6 and selective colocalization at nodes of Ranvier of dorsal root axons
-
Wittmack E, Rush AM, Craner MJ, Goldfarb M, Waxman SG, Dib-Hajj SD (2004) Fibroblast growth factor homologous factor 2B: association with Nav1.6 and selective colocalization at nodes of Ranvier of dorsal root axons. J Neurosci 24:6765-6775
-
(2004)
J Neurosci
, vol.24
, pp. 6765-6775
-
-
Wittmack, E.1
Rush, A.M.2
Craner, M.J.3
Goldfarb, M.4
Waxman, S.G.5
Dib-Hajj, S.D.6
-
41
-
-
28244494121
-
Fibroblast growth factor 14 is an intracellular modulator of voltage-gated sodium channels
-
Lou JY, Laezza F, Gerber BR, Xiao M, Yamada KA, Hartmann H, Craig AM, Nerbonne JM, Ornitz DM (2005) Fibroblast growth factor 14 is an intracellular modulator of voltage-gated sodium channels. J Physiol 569:179-193
-
(2005)
J Physiol
, vol.569
, pp. 179-193
-
-
Lou, J.Y.1
Laezza, F.2
Gerber, B.R.3
Xiao, M.4
Yamada, K.A.5
Hartmann, H.6
Craig, A.M.7
Nerbonne, J.M.8
Ornitz, D.M.9
-
42
-
-
33744501520
-
Differential modulation of sodium channel Na(v)1.6 by two members of the fibroblast growth factor homologous factor 2 subfamily
-
Rush AM, Wittmack EK, Tyrrell L, Black JA, Dib-Hajj SD, Waxman SG (2006) Differential modulation of sodium channel Na(v)1.6 by two members of the fibroblast growth factor homologous factor 2 subfamily. Eur J Neurosci 23:2551-2562
-
(2006)
Eur J Neurosci
, vol.23
, pp. 2551-2562
-
-
Rush, A.M.1
Wittmack, E.K.2
Tyrrell, L.3
Black, J.A.4
Dib-Hajj, S.D.5
Waxman, S.G.6
-
43
-
-
34547192748
-
Fibroblast growth factor homologous factors control neuronal excitability through modulation of voltage-gated sodium channels
-
Goldfarb M, Schoorlemmer J, Williams A, Diwakar S, Wang Q, Huang X, Giza J, Tchetchik D, Kelley K, Vega A, Matthews G, Rossi P, Ornitz DM, DAngelo E (2007) Fibroblast growth factor homologous factors control neuronal excitability through modulation of voltage-gated sodium channels. Neuron 55:449-463
-
(2007)
Neuron
, vol.55
, pp. 449-463
-
-
Goldfarb, M.1
Schoorlemmer, J.2
Williams, A.3
Diwakar, S.4
Wang, Q.5
Huang, X.6
Giza, J.7
Tchetchik, D.8
Kelley, K.9
Vega, A.10
Matthews, G.11
Rossi, P.12
Ornitz, D.M.13
Dangelo, E.14
-
44
-
-
68349095136
-
FGF14N-terminal splice variants differentially modulate Nav1.2 and Nav1.6-encoded sodium channels
-
Laezza F, Lampert A, Kozel MA, Gerber BR, Rush AM, Nerbonne JM, Waxman SG, Dib-Hajj SD, Ornitz DM (2009) FGF14N-terminal splice variants differentially modulate Nav1.2 and Nav1.6-encoded sodium channels. Mol Cell Neurosci 42:90-101
-
(2009)
Mol Cell Neurosci
, vol.42
, pp. 90-101
-
-
Laezza, F.1
Lampert, A.2
Kozel, M.A.3
Gerber, B.R.4
Rush, A.M.5
Nerbonne, J.M.6
Waxman, S.G.7
Dib-Hajj, S.D.8
Ornitz, D.M.9
-
45
-
-
77957263704
-
Long-term inactivation particle for voltage-gated sodium channels
-
Dover K, Solinas S, DAngelo E, Goldfarb M (2010) Long-term inactivation particle for voltage-gated sodium channels. J Physiol 588:3695-3711
-
(2010)
J Physiol
, vol.588
, pp. 3695-3711
-
-
Dover, K.1
Solinas, S.2
Dangelo, E.3
Goldfarb, M.4
-
46
-
-
18144380347
-
Fibroblast growth factor homologous factors: Evolution, structure, and function
-
Goldfarb M (2005) Fibroblast growth factor homologous factors: evolution, structure, and function. Cytokine Growth Factor Rev 16:215-220
-
(2005)
Cytokine Growth Factor Rev
, vol.16
, pp. 215-220
-
-
Goldfarb, M.1
-
47
-
-
79251501315
-
Fibroblast growth factors: From molecular evolution to roles in development, metabolism and disease
-
Itoh N, Ornitz DM (2011) Fibroblast growth factors: from molecular evolution to roles in development, metabolism and disease. J Biochem 149:121-130
-
(2011)
J Biochem
, vol.149
, pp. 121-130
-
-
Itoh, N.1
Ornitz, D.M.2
-
48
-
-
67650533766
-
Crystal structure of a fibroblast growth factor homologous factor (FHF) defines a conserved surface on FHFs for binding and modulation of voltage-gated sodium channels
-
Goetz R, Dover K, Laezza F, Shtraizent N, Tchetchik D, Huang X, Eliseenkova AV, Xu C, Neubert TA, Ornitz DM, Goldfarb M, Mohammadi M (2009) Crystal structure of a fibroblast growth factor homologous factor (FHF) defines a conserved surface on FHFs for binding and modulation of voltage-gated sodium channels. J Biol Chem 284:17883-17896
-
(2009)
J Biol Chem
, vol.284
, pp. 17883-17896
-
-
Goetz, R.1
Dover, K.2
Laezza, F.3
Shtraizent, N.4
Tchetchik, D.5
Huang, X.6
Eliseenkova, A.V.7
Xu, C.8
Neubert, T.A.9
Ornitz, D.M.10
Goldfarb, M.11
Mohammadi, M.12
-
49
-
-
11244253209
-
Interactions of local anesthetics with voltage-gated Na+ channels
-
Nau C, Wang GK (2004) Interactions of local anesthetics with voltage-gated Na+ channels. J Membr Biol 201:1-8
-
(2004)
J Membr Biol
, vol.201
, pp. 1-8
-
-
Nau, C.1
Wang, G.K.2
-
50
-
-
27844589940
-
Molecular modeling of local anesthetic drug binding by voltage-gated sodium channels
-
Lipkind GM, Fozzard HA (2005) Molecular modeling of local anesthetic drug binding by voltage-gated sodium channels. Mol Pharmacol 68:1611-1622
-
(2005)
Mol Pharmacol
, vol.68
, pp. 1611-1622
-
-
Lipkind, G.M.1
Fozzard, H.A.2
-
51
-
-
34249674070
-
Charge at the lidocaine binding site residue Phe-1759 affects permeation in human cardiac voltage-gated sodium channels
-
McNulty MM, Edgerton GB, Shah RD, Hanck DA, Fozzard HA, Lipkind GM (2007) Charge at the lidocaine binding site residue Phe-1759 affects permeation in human cardiac voltage-gated sodium channels. J Physiol 581:741-755
-
(2007)
J Physiol
, vol.581
, pp. 741-755
-
-
McNulty, M.M.1
Edgerton, G.B.2
Shah, R.D.3
Hanck, D.A.4
Fozzard, H.A.5
Lipkind, G.M.6
-
52
-
-
0025827588
-
Frequency and voltage-dependent inhibition of type IIA Na+ channels, expressed in a mammalian cell line, by local anesthetic, antiarrhythmic, and anticonvulsant drugs
-
Ragsdale DS, Scheuer T, Catterall WA (1991) Frequency and voltage-dependent inhibition of type IIA Na+ channels, expressed in a mammalian cell line, by local anesthetic, antiarrhythmic, and anticonvulsant drugs. Mol Pharmacol 40:756-765
-
(1991)
Mol Pharmacol
, vol.40
, pp. 756-765
-
-
Ragsdale, D.S.1
Scheuer, T.2
Catterall, W.A.3
-
53
-
-
0027944683
-
Molecular determinants of state-dependent block of Na+ channels by local anesthetics
-
Ragsdale DS, McPhee JC, Scheuer T, Catterall WA (1994) Molecular determinants of state-dependent block of Na+ channels by local anesthetics. Science 265:1724-1728
-
(1994)
Science
, vol.265
, pp. 1724-1728
-
-
Ragsdale, D.S.1
McPhee, J.C.2
Scheuer, T.3
Catterall, W.A.4
-
54
-
-
0029787945
-
Common molecular determinants of local anesthetic, antiarrhythmic, and anticonvulsant block of voltage-gated Na+ channels
-
Ragsdale DS, McPhee JC, Scheuer T, Catterall WA (1996) Common molecular determinants of local anesthetic, antiarrhythmic, and anticonvulsant block of voltage-gated Na+ channels. Proc Natl Acad Sci USA 93:9270-9275
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 9270-9275
-
-
Ragsdale, D.S.1
McPhee, J.C.2
Scheuer, T.3
Catterall, W.A.4
-
55
-
-
0031725974
-
Lysine point mutations in Na+ channel D4-S6 reduce inactivated channel block by local anesthetics
-
Wright SN, Wang SY, Wang GK (1998) Lysine point mutations in Na+ channel D4-S6 reduce inactivated channel block by local anesthetics. Mol Pharmacol 54:733-739
-
(1998)
Mol Pharmacol
, vol.54
, pp. 733-739
-
-
Wright, S.N.1
Wang, S.Y.2
Wang, G.K.3
-
56
-
-
10644228691
-
Accessibility of mid-segment domain IV S6 residues of the voltage-gated Na+ channel to methanethiosulfonate reagents
-
Sunami A, Tracey A, Glaaser IW, Lipkind GM, Hanck DA, Fozzard HA (2004) Accessibility of mid-segment domain IV S6 residues of the voltage-gated Na+ channel to methanethiosulfonate reagents. J Physiol 561:403-413
-
(2004)
J Physiol
, vol.561
, pp. 403-413
-
-
Sunami, A.1
Tracey, A.2
Glaaser, I.W.3
Lipkind, G.M.4
Hanck, D.A.5
Fozzard, H.A.6
-
57
-
-
0029133965
-
On the molecular nature of the lidocaine receptor of cardiac Na+ channels. Modification of block by alterations in the alpha-subunit III-IV interdomain
-
Bennett PB, Valenzuela C, Chen LQ, Kallen RG (1995) On the molecular nature of the lidocaine receptor of cardiac Na+ channels. Modification of block by alterations in the alpha-subunit III-IV interdomain. Circ Res 77:584-592
-
(1995)
Circ Res
, vol.77
, pp. 584-592
-
-
Bennett, P.B.1
Valenzuela, C.2
Chen, L.Q.3
Kallen, R.G.4
-
58
-
-
0033635318
-
Block of wild-type and inactivation-deficient cardiac sodium channels IFM/QQQ stably expressed in mammalian cells
-
Grant AO, Chandra R, Keller C, Carboni M, Starmer CF (2000) Block of wild-type and inactivation-deficient cardiac sodium channels IFM/QQQ stably expressed in mammalian cells. Biophys J 79:3019-3035
-
(2000)
Biophys J
, vol.79
, pp. 3019-3035
-
-
Grant, A.O.1
Chandra, R.2
Keller, C.3
Carboni, M.4
Starmer, C.F.5
-
59
-
-
34347216385
-
Outward stabilization of the S4 segments in domains III and IV enhances lidocaine block of sodium channels
-
Sheets MF, Hanck DA (2007) Outward stabilization of the S4 segments in domains III and IV enhances lidocaine block of sodium channels. J Physiol 582:317-334
-
(2007)
J Physiol
, vol.582
, pp. 317-334
-
-
Sheets, M.F.1
Hanck, D.A.2
-
60
-
-
0032922295
-
Block of brain sodium channels by peptide mimetics of the isoleucine, phenylalanine, and methionine (IFM) motif from the inactivation gate
-
Eaholtz G, Colvin A, Leonard D, Taylor C, Catterall WA (1999) Block of brain sodium channels by peptide mimetics of the isoleucine, phenylalanine, and methionine (IFM) motif from the inactivation gate. J Gen Physiol 113:279-294
-
(1999)
J Gen Physiol
, vol.113
, pp. 279-294
-
-
Eaholtz, G.1
Colvin, A.2
Leonard, D.3
Taylor, C.4
Catterall, W.A.5
-
61
-
-
0031010957
-
Resurgent sodium current and action potential formation in dissociated cerebellar Purkinje neurons
-
Raman IM, Bean BP (1997) Resurgent sodium current and action potential formation in dissociated cerebellar Purkinje neurons. J Neurosci 17:4517-4526
-
(1997)
J Neurosci
, vol.17
, pp. 4517-4526
-
-
Raman, I.M.1
Bean, B.P.2
-
62
-
-
33646342482
-
Kinetic and functional analysis of transient, persistent and resurgent sodium currents in rat cerebellar granule cells in situ: An electrophysiological and modelling study
-
Magistretti J, Castelli L, Forti L, DAngelo E (2006) Kinetic and functional analysis of transient, persistent and resurgent sodium currents in rat cerebellar granule cells in situ: an electrophysiological and modelling study. J Physiol 573:83-106
-
(2006)
J Physiol
, vol.573
, pp. 83-106
-
-
Magistretti, J.1
Castelli, L.2
Forti, L.3
Dangelo, E.4
-
63
-
-
34547106281
-
Resurgent Na+ current in pyramidal neurones of rat perirhinal cortex: Axonal location of channels and contribution to depolarizing drive during repetitive firing
-
Castelli L, Biella G, Toselli M, Magistretti J (2007) Resurgent Na+ current in pyramidal neurones of rat perirhinal cortex: axonal location of channels and contribution to depolarizing drive during repetitive firing. J Physiol 582:1179-1193
-
(2007)
J Physiol
, vol.582
, pp. 1179-1193
-
-
Castelli, L.1
Biella, G.2
Toselli, M.3
Magistretti, J.4
-
64
-
-
0038236735
-
The contribution of resurgent sodium current to high-frequency firing in Purkinje neurons: An experimental and modeling study
-
Khaliq ZM, Gouwens NW, Raman IM (2003) The contribution of resurgent sodium current to high-frequency firing in Purkinje neurons: an experimental and modeling study. J Neurosci 23:4899-4912
-
(2003)
J Neurosci
, vol.23
, pp. 4899-4912
-
-
Khaliq, Z.M.1
Gouwens, N.W.2
Raman, I.M.3
-
65
-
-
77955463322
-
Control of transient, resurgent, and persistent current by open-channel block by Na channel beta4 in cultured cerebellar granule neurons
-
Bant JS, Raman IM (2010) Control of transient, resurgent, and persistent current by open-channel block by Na channel beta4 in cultured cerebellar granule neurons. Proc Natl Acad Sci USA 107:12357-12362
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 12357-12362
-
-
Bant, J.S.1
Raman, I.M.2
-
66
-
-
0037092416
-
A role for phosphorylation in the maintenance of resurgent sodium current in cerebellar Purkinje neurons
-
Grieco TM, Afshari FS, Raman IM (2002) A role for phosphorylation in the maintenance of resurgent sodium current in cerebellar Purkinje neurons. J Neurosci 22:3100-3107
-
(2002)
J Neurosci
, vol.22
, pp. 3100-3107
-
-
Grieco, T.M.1
Afshari, F.S.2
Raman, I.M.3
-
67
-
-
12344303542
-
Open-channel block by the cytoplasmic tail of sodium channel beta4 as a mechanism for resurgent sodium current
-
Grieco TM, Malhotra JD, Chen C, Isom LL, Raman IM (2005) Open-channel block by the cytoplasmic tail of sodium channel beta4 as a mechanism for resurgent sodium current. Neuron 45:233-244
-
(2005)
Neuron
, vol.45
, pp. 233-244
-
-
Grieco, T.M.1
Malhotra, J.D.2
Chen, C.3
Isom, L.L.4
Raman, I.M.5
-
68
-
-
77951573989
-
Inwardly permeating Na ions generate the voltage dependence of resurgent Na current in cerebellar Purkinje neurons
-
Aman TK, Raman IM (2010) Inwardly permeating Na ions generate the voltage dependence of resurgent Na current in cerebellar Purkinje neurons. J Neurosci 30:5629-5634
-
(2010)
J Neurosci
, vol.30
, pp. 5629-5634
-
-
Aman, T.K.1
Raman, I.M.2
-
69
-
-
33644603393
-
Time-dependent block and resurgent tail currents induced by mouse beta4(154-167) peptide in cardiac Na+ channels
-
Wang GK, Edrich T, Wang SY (2006) Time-dependent block and resurgent tail currents induced by mouse beta4(154-167) peptide in cardiac Na+ channels. J Gen Physiol 127:277-289
-
(2006)
J Gen Physiol
, vol.127
, pp. 277-289
-
-
Wang, G.K.1
Edrich, T.2
Wang, S.Y.3
-
70
-
-
3142695482
-
Sodium currents in subthalamic nucleus neurons from Nav1.6-null mice
-
Do MT, Bean BP (2004) Sodium currents in subthalamic nucleus neurons from Nav1.6-null mice. J Neurophysiol 92:726-733
-
(2004)
J Neurophysiol
, vol.92
, pp. 726-733
-
-
Do, M.T.1
Bean, B.P.2
-
71
-
-
37149019607
-
Nav1.6 sodium channels are critical to pacemaking and fast spiking in globus pallidus neurons
-
Mercer JN, Chan CS, Tkatch T, Held J, Surmeier DJ (2007) Nav1.6 sodium channels are critical to pacemaking and fast spiking in globus pallidus neurons. J Neurosci 27:13552-13566
-
(2007)
J Neurosci
, vol.27
, pp. 13552-13566
-
-
Mercer, J.N.1
Chan, C.S.2
Tkatch, T.3
Held, J.4
Surmeier, D.J.5
-
72
-
-
35348904490
-
Reduced sodium current in Purkinje neurons from Nav1.1 mutant mice: Implications for ataxia in severe myoclonic epilepsy in infancy
-
Kalume F, Yu FH, Westenbroek RE, Scheuer T, Catterall WA (2007) Reduced sodium current in Purkinje neurons from Nav1.1 mutant mice: implications for ataxia in severe myoclonic epilepsy in infancy. J Neurosci 27:11065-11074
-
(2007)
J Neurosci
, vol.27
, pp. 11065-11074
-
-
Kalume, F.1
Yu, F.H.2
Westenbroek, R.E.3
Scheuer, T.4
Catterall, W.A.5
-
73
-
-
77949494524
-
Persistent Nav1.6 current at axon initial segments tunes spike timing of cerebellar granule cells
-
Osorio N, Cathala L, Meisler MH, Crest M, Magistretti J, Delmas P (2010) Persistent Nav1.6 current at axon initial segments tunes spike timing of cerebellar granule cells. J Physiol 588:651-670
-
(2010)
J Physiol
, vol.588
, pp. 651-670
-
-
Osorio, N.1
Cathala, L.2
Meisler, M.H.3
Crest, M.4
Magistretti, J.5
Delmas, P.6
-
74
-
-
79251569257
-
Nav1.7 mutations associated with paroxysmal extreme pain disorder, but not erythromelalgia, enhance Navbeta4 peptidemediated resurgent sodium currents
-
Theile JW, Jarecki BW, Piekarz AD, Cummins TR (2011) Nav1.7 mutations associated with paroxysmal extreme pain disorder, but not erythromelalgia, enhance Navbeta4 peptidemediated resurgent sodium currents. J Physiol 589:597-608
-
(2011)
J Physiol
, vol.589
, pp. 597-608
-
-
Theile, J.W.1
Jarecki, B.W.2
Piekarz, A.D.3
Cummins, T.R.4
-
75
-
-
0842344423
-
Production of resurgent current in NaV1.6-null Purkinje neurons by slowing sodium channel inactivation with beta-pompilidotoxin
-
Grieco TM, Raman IM (2004) Production of resurgent current in NaV1.6-null Purkinje neurons by slowing sodium channel inactivation with beta-pompilidotoxin. J Neurosci 24:35-42
-
(2004)
J Neurosci
, vol.24
, pp. 35-42
-
-
Grieco, T.M.1
Raman, I.M.2
-
76
-
-
0142250836
-
Altered neuronal excitability in cerebellar granule cells of mice lacking calretinin
-
Gall D, Roussel C, Susa I, DAngelo E, Rossi P, Bearzatto B, Galas MC, Blum D, Schurmans S, Schiffmann SN (2003) Altered neuronal excitability in cerebellar granule cells of mice lacking calretinin. J Neurosci 23:9320-9327
-
(2003)
J Neurosci
, vol.23
, pp. 9320-9327
-
-
Gall, D.1
Roussel, C.2
Susa, I.3
Dangelo, E.4
Rossi, P.5
Bearzatto, B.6
Galas, M.C.7
Blum, D.8
Schurmans, S.9
Schiffmann, S.N.10
-
77
-
-
33845567864
-
Polarized distribution of ion channels within microdomains of the axon initial segment
-
Van Wart A, Trimmer JS, Matthews G (2007) Polarized distribution of ion channels within microdomains of the axon initial segment. J Comp Neurol 500:339-352
-
(2007)
J Comp Neurol
, vol.500
, pp. 339-352
-
-
Van Wart, A.1
Trimmer, J.S.2
Matthews, G.3
-
78
-
-
58149393984
-
Cell-type-dependent molecular composition of the axon initial segment
-
Lorincz A, Nusser Z (2008) Cell-type-dependent molecular composition of the axon initial segment. J Neurosci 28:14329-14340
-
(2008)
J Neurosci
, vol.28
, pp. 14329-14340
-
-
Lorincz, A.1
Nusser, Z.2
-
79
-
-
52049087810
-
Nav1.1 is predominantly expressed in nodes of Ranvier and axon initial segments
-
Duflocq A, Le Bras B, Bullier E, Couraud F, Davenne M (2008) Nav1.1 is predominantly expressed in nodes of Ranvier and axon initial segments. Mol Cell Neurosci 39:180-192
-
(2008)
Mol Cell Neurosci
, vol.39
, pp. 180-192
-
-
Duflocq, A.1
Le Bras, B.2
Bullier, E.3
Couraud, F.4
Davenne, M.5
-
80
-
-
57449109506
-
FGF14 regulates the intrinsic excitability of cerebellar Purkinje neurons
-
Shakkottai VG, Xiao M, Xu L, Wong M, Nerbonne JM, Ornitz DM, Yamada KA (2009) FGF14 regulates the intrinsic excitability of cerebellar Purkinje neurons. Neurobiol Dis 33:81-88
-
(2009)
Neurobiol Dis
, vol.33
, pp. 81-88
-
-
Shakkottai, V.G.1
Xiao, M.2
Xu, L.3
Wong, M.4
Nerbonne, J.M.5
Ornitz, D.M.6
Yamada, K.A.7
-
81
-
-
78449246774
-
Presynaptic resurgent Na+ currents sculpt the action potential waveform and increase firing reliability at a CNS nerve terminal
-
Kim JH, Kushmerick C, von Gersdorff H (2010) Presynaptic resurgent Na+ currents sculpt the action potential waveform and increase firing reliability at a CNS nerve terminal. J Neurosci 30:15479-15490
-
(2010)
J Neurosci
, vol.30
, pp. 15479-15490
-
-
Kim, J.H.1
Kushmerick, C.2
Von Gersdorff, H.3
-
83
-
-
0028903712
-
Activitydependent action potential invasion and calcium influx into hippocampal CA1 dendrites
-
Spruston N, Schiller Y, Stuart G, Sakmann B (1995) Activitydependent action potential invasion and calcium influx into hippocampal CA1 dendrites. Science 268:297-300
-
(1995)
Science
, vol.268
, pp. 297-300
-
-
Spruston, N.1
Schiller, Y.2
Stuart, G.3
Sakmann, B.4
-
84
-
-
0028818821
-
Frequency-dependent propagation of sodium action potentials in dendrites of hippocampal CA1 pyramidal neurons
-
Callaway JC, Ross WN (1995) Frequency-dependent propagation of sodium action potentials in dendrites of hippocampal CA1 pyramidal neurons. J Neurophysiol 74:1395-1403
-
(1995)
J Neurophysiol
, vol.74
, pp. 1395-1403
-
-
Callaway, J.C.1
Ross, W.N.2
-
85
-
-
0030848004
-
Prolonged sodium channel inactivation contributes to dendritic action potential attenuation in hippocampal pyramidal neurons
-
Jung HY, Mickus T, Spruston N (1997) Prolonged sodium channel inactivation contributes to dendritic action potential attenuation in hippocampal pyramidal neurons. J Neurosci 17:6639-6646
-
(1997)
J Neurosci
, vol.17
, pp. 6639-6646
-
-
Jung, H.Y.1
Mickus, T.2
Spruston, N.3
-
86
-
-
0030873774
-
Slow recovery from inactivation of Na + channels underlies the activity-dependent attenuation of dendritic action potentials in hippocampal CA1 pyramidal neurons
-
Colbert CM, Magee JC, Hoffman DA, Johnston D (1997) Slow recovery from inactivation of Na + channels underlies the activity-dependent attenuation of dendritic action potentials in hippocampal CA1 pyramidal neurons. J Neurosci 17:6512-6521
-
(1997)
J Neurosci
, vol.17
, pp. 6512-6521
-
-
Colbert, C.M.1
Magee, J.C.2
Hoffman, D.A.3
Johnston, D.4
|