-
1
-
-
0035853405
-
Novel arrhythmogenic mechanism revealed by a long-qt syndrome mutation in the cardiac Na(+) channel
-
Abriel, H., C. Cabo, X. H. Wehrens, I. Rivolta, H. K. Motoike, M. Memmi, C. Napolitano, S. G. Priori, and R. S. Kass. 2001. Novel arrhythmogenic mechanism revealed by a long-qt syndrome mutation in the cardiac Na(+) channel. Circ. Res. 88:740-745.
-
(2001)
Circ. Res.
, vol.88
, pp. 740-745
-
-
Abriel, H.1
Cabo, C.2
Wehrens, X.H.3
Rivolta, I.4
Motoike, H.K.5
Memmi, M.6
Napolitano, C.7
Priori, S.G.8
Kass, R.S.9
-
2
-
-
0035860984
-
Postmortem molecular analysis of SCN5A defects in sudden infant death syndrome
-
Ackerman, M. J., B. L. Siu, W. Q. Sturner, D. J. Tester, C. R. Valdivia, J. C. Makielski, and J. A. Towbin. 2001. Postmortem molecular analysis of SCN5A defects in sudden infant death syndrome. JAMA. 286:2264-2269.
-
(2001)
JAMA
, vol.286
, pp. 2264-2269
-
-
Ackerman, M.J.1
Siu, B.L.2
Sturner, W.Q.3
Tester, D.J.4
Valdivia, C.R.5
Makielski, J.C.6
Towbin, J.A.7
-
3
-
-
0034637507
-
A novel SCN5A mutation associated with idiopathic ventricular fibrillation without typical ECG findings of Brugada syndrome
-
Akai, J., N. Makita, H. Sakurada, N. Shirai, K. Ueda, A. Kitabatake, K. Nakazawa, A. Kimura, and M. Hiraoka. 2000. A novel SCN5A mutation associated with idiopathic ventricular fibrillation without typical ECG findings of Brugada syndrome. FEBS Lett. 479:29-34.
-
(2000)
FEBS Lett.
, vol.479
, pp. 29-34
-
-
Akai, J.1
Makita, N.2
Sakurada, H.3
Shirai, N.4
Ueda, K.5
Kitabatake, A.6
Nakazawa, K.7
Kimura, A.8
Hiraoka, M.9
-
4
-
-
0032572594
-
Novel LQT-3 mutation affects Na+ channel activity through interactions between alpha- and beta1-subunits
-
An, R. H., X. L. Wang, B. Kerem, J. Benhorin, A. Medina, M. Goldmit, and R. S. Kass. 1998. Novel LQT-3 mutation affects Na+ channel activity through interactions between alpha- and beta1-subunits. Circ. Res. 83:141-146.
-
(1998)
Circ. Res.
, vol.83
, pp. 141-146
-
-
An, R.H.1
Wang, X.L.2
Kerem, B.3
Benhorin, J.4
Medina, A.5
Goldmit, M.6
Kass, R.S.7
-
5
-
-
0036087310
-
Inherited sodium channelopathies: Models for acquired arrhythmias?
-
Balser, J. R. 2002. Inherited sodium channelopathies: models for acquired arrhythmias? Am. J. Physiol. Heart Circ. Physiol. 282:H1175-H1180.
-
(2002)
Am. J. Physiol. Heart Circ. Physiol.
, vol.282
-
-
Balser, J.R.1
-
6
-
-
0034731314
-
Biophysical phenotypes of SCN5A mutations causing long QT and Brugada syndromes
-
Baroudi, G., and M. Chahine. 2000. Biophysical phenotypes of SCN5A mutations causing long QT and Brugada syndromes. FEBS Lett. 487:224-228.
-
(2000)
FEBS Lett.
, vol.487
, pp. 224-228
-
-
Baroudi, G.1
Chahine, M.2
-
7
-
-
0029097799
-
Molecular mechanism for an inherited cardiac arrhythmia
-
Bennett, P. B., K. Yazawa, N. Makita, and A. L. George. 1995. Molecular mechanism for an inherited cardiac arrhythmia. Nature (Lond.). 376:683-685.
-
(1995)
Nature (Lond.)
, vol.376
, pp. 683-685
-
-
Bennett, P.B.1
Yazawa, K.2
Makita, N.3
George, A.L.4
-
8
-
-
0033533990
-
A single Na(+) channel mutation causing both long-QT and Brugada syndromes
-
Bezzina, C., M. W. Veldkamp, M. P. van den Berg, A. V. Postma, M. B. Rook, J. W. Viersma, I. M. van Langen, G. Tan-Sindhunata, M. T. Bink-Boelkens, A. H. van Der Hout, M. M. Mannens, and A. A. Wilde. 1999. A single Na(+) channel mutation causing both long-QT and Brugada syndromes. Circ. Res. 85:1206-1213.
-
(1999)
Circ. Res.
, vol.85
, pp. 1206-1213
-
-
Bezzina, C.1
Veldkamp, M.W.2
Van Den Berg, M.P.3
Postma, A.V.4
Rook, M.B.5
Viersma, J.W.6
Van Langen, I.M.7
Tan-Sindhunata, G.8
Bink-Boelkens, M.T.9
Van Der Hout, A.H.10
Mannens, M.M.11
Wilde, A.A.12
-
9
-
-
0029026638
-
Structure and function of voltage-gated ion channels
-
Catterall, W. A. 1995. Structure and function of voltage-gated ion channels. Annu. Rev. Biochem. 64:493-531.
-
(1995)
Annu. Rev. Biochem.
, vol.64
, pp. 493-531
-
-
Catterall, W.A.1
-
10
-
-
0036801431
-
Defective cardiac ion channels: From mutations to clinical syndromes
-
Clancy, C. E., and R. S. Kass. 2002. Defective cardiac ion channels: from mutations to clinical syndromes. J. Clin. Invest. 110:1075-1077.
-
(2002)
J. Clin. Invest.
, vol.110
, pp. 1075-1077
-
-
Clancy, C.E.1
Kass, R.S.2
-
11
-
-
0036839970
-
Insights into the molecular mechanisms of bradycardia-triggered arrhythmias in long QT-3 syndrome
-
Clancy, C. E., M. Tateyama, and R. S. Kass. 2002. Insights into the molecular mechanisms of bradycardia-triggered arrhythmias in long QT-3 syndrome. J. Clin. Invest. 110:1251-1262.
-
(2002)
J. Clin. Invest.
, vol.110
, pp. 1251-1262
-
-
Clancy, C.E.1
Tateyama, M.2
Kass, R.S.3
-
12
-
-
0037088663
-
Secondary structure of the human cardiac Na+ channel C terminus. Evidence for a role of helical structures in modulation of channel inactivation
-
Cormier, J. W., I. Rivolta, M. Tateyama, A. S. Yang, and R. S. Kass. 2002. Secondary structure of the human cardiac Na+ channel C terminus. Evidence for a role of helical structures in modulation of channel inactivation. J. Biol. Chem. 277:9233-9241.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 9233-9241
-
-
Cormier, J.W.1
Rivolta, I.2
Tateyama, M.3
Yang, A.S.4
Kass, R.S.5
-
13
-
-
0343819791
-
Electrophysiological characterization of SCN5A mutations causing long QT (E1784K) and Brugada (R1512W and R1432G) syndromes
-
Deschenes, I., G. Baroudi, M. Berthet, I. Barde, T. Chalvidan, I. Denjoy, P. Guicheney, and M. Chahine. 2000. Electrophysiological characterization of SCN5A mutations causing long QT (E1784K) and Brugada (R1512W and R1432G) syndromes. Cardiovasc. Res. 46:55-65.
-
(2000)
Cardiovasc. Res.
, vol.46
, pp. 55-65
-
-
Deschenes, I.1
Baroudi, G.2
Berthet, M.3
Barde, I.4
Chalvidan, T.5
Denjoy, I.6
Guicheney, P.7
Chahine, M.8
-
14
-
-
0032144024
-
Human sodium channel gating defects caused by missense mutations in S6 segments associated with myotonia: S804F and V1293I
-
Green, D. S., A. L. George, Jr., and S. C. Cannon. 1998. Human sodium channel gating defects caused by missense mutations in S6 segments associated with myotonia: S804F and V1293I. J. Physiol. 510:685-694.
-
(1998)
J. Physiol.
, vol.510
, pp. 685-694
-
-
Green, D.S.1
George Jr., A.L.2
Cannon, S.C.3
-
15
-
-
0034303612
-
Neuronal KCNQ potassium channels: Physiology and role in disease
-
Jentsch, T. J. 2000. Neuronal KCNQ potassium channels: physiology and role in disease. Nat. Rev. Neurosci. 1:21-30.
-
(2000)
Nat. Rev. Neurosci.
, vol.1
, pp. 21-30
-
-
Jentsch, T.J.1
-
16
-
-
0033898774
-
Pathophysiology of KCNQ channels: Neonatal epilepsy and progressive deafness
-
Jentsch, T. J., B. C. Schroeder, C. Kubisch, T. Friedrich, and V. Stein. 2000. Pathophysiology of KCNQ channels: neonatal epilepsy and progressive deafness. Epilepsia. 41:1068-1069.
-
(2000)
Epilepsia
, vol.41
, pp. 1068-1069
-
-
Jentsch, T.J.1
Schroeder, B.C.2
Kubisch, C.3
Friedrich, T.4
Stein, V.5
-
17
-
-
0035376721
-
Human muscle voltage-gated ion channels and hereditary disease
-
Jurkat-Rott, K., and F. Lehmann-Horn. 2001. Human muscle voltage-gated ion channels and hereditary disease. Curr. Opin. Pharmacol. 1:280-287.
-
(2001)
Curr. Opin. Pharmacol.
, vol.1
, pp. 280-287
-
-
Jurkat-Rott, K.1
Lehmann-Horn, F.2
-
18
-
-
0035936798
-
Molecular and cellular mechanisms of cardiac arrhythmias
-
Keating, M. T., and M. C. Sanguinetti. 2001. Molecular and cellular mechanisms of cardiac arrhythmias. Cell. 104:569-580.
-
(2001)
Cell
, vol.104
, pp. 569-580
-
-
Keating, M.T.1
Sanguinetti, M.C.2
-
19
-
-
0036260284
-
The neuronal channelopathies
-
Kullmann, D. M. 2002. The neuronal channelopathies. Brain. 125:1177-1195.
-
(2002)
Brain
, vol.125
, pp. 1177-1195
-
-
Kullmann, D.M.1
-
21
-
-
0036020181
-
Channel openings are necessary but not sufficient for use-dependent block of cardiac Na(+) channels by flecainide: Evidence from the analysis of disease-linked mutations
-
Liu, H., M. Tateyama, C. E. Clancy, H. Abriel, and R. S. Kass. 2002. Channel openings are necessary but not sufficient for use-dependent block of cardiac Na(+) channels by flecainide: evidence from the analysis of disease-linked mutations. J. Gen. Physiol. 120:39-51.
-
(2002)
J. Gen. Physiol.
, vol.120
, pp. 39-51
-
-
Liu, H.1
Tateyama, M.2
Clancy, C.E.3
Abriel, H.4
Kass, R.S.5
-
22
-
-
0037071896
-
Molecular basis of an inherited epilepsy
-
Lossin, C., D. W. Wang, T. H. Rhodes, C. G. Vanoye, and A. L. George, Jr. 2002. Molecular basis of an inherited epilepsy. Neuron. 34:877-884.
-
(2002)
Neuron
, vol.34
, pp. 877-884
-
-
Lossin, C.1
Wang, D.W.2
Rhodes, T.H.3
Vanoye, C.G.4
George Jr., A.L.5
-
23
-
-
0037049999
-
Cardiac channelopathies
-
Marban, E. 2002. Cardiac channelopathies. Nature. 415:213-218.
-
(2002)
Nature
, vol.415
, pp. 213-218
-
-
Marban, E.1
-
24
-
-
0034068087
-
Ion channel surprises: Prokaryotes do it again!
-
Miller, C. 2000a. Ion channel surprises: prokaryotes do it again! Neuron. 25:7-9.
-
(2000)
Neuron
, vol.25
, pp. 7-9
-
-
Miller, C.1
-
25
-
-
0034111512
-
Ion channels: Doing hard chemistry with hard ions
-
Miller, C. 2000b. Ion channels: doing hard chemistry with hard ions. Curr. Opin. Chem. Biol. 4:148-151.
-
(2000)
Curr. Opin. Chem. Biol.
, vol.4
, pp. 148-151
-
-
Miller, C.1
-
27
-
-
0142105837
-
Apolipoprotein[a] secretion from hepatoma cells is regulated in a size-dependent mannor by alterations in disulfide bond formation
-
Nassir, F., Y. Xie, and N. O. Davidson. 2003. Apolipoprotein[a] secretion from hepatoma cells is regulated in a size-dependent mannor by alterations in disulfide bond formation. J. Lipid Res. 44:816-827.
-
(2003)
J. Lipid Res.
, vol.44
, pp. 816-827
-
-
Nassir, F.1
Xie, Y.2
Davidson, N.O.3
-
28
-
-
0031047595
-
Subconductance states of a mutant NMDA receptor channel kinetics, calcium, and voltage dependence
-
Premkumar, L. S., F. Qin, and A. Auerbach. 1997. Subconductance states of a mutant NMDA receptor channel kinetics, calcium, and voltage dependence. J. Gen. Physiol. 109:181-189.
-
(1997)
J. Gen. Physiol.
, vol.109
, pp. 181-189
-
-
Premkumar, L.S.1
Qin, F.2
Auerbach, A.3
-
29
-
-
0030061670
-
Estimating single-channel kinetic parameters from idealized patch-clamp data containing missed events
-
Qin, F., A. Auerbach, and F. Sachs. 1996. Estimating single-channel kinetic parameters from idealized patch-clamp data containing missed events. Biophys. J. 70:264-280.
-
(1996)
Biophys. J.
, vol.70
, pp. 264-280
-
-
Qin, F.1
Auerbach, A.2
Sachs, F.3
-
30
-
-
0035903135
-
Inherited Brugada and long QT-3 syndrome mutations of a single residue of the cardiac sodium channel confer distinct channel and clinical phenotypes
-
Rivolta, I., H. Abriel, M. Tateyama, H. Liu, M. Memmi, P. Vardas, C. Napolitano, S. G. Priori, and R. S. Kass. 2001. Inherited Brugada and long QT-3 syndrome mutations of a single residue of the cardiac sodium channel confer distinct channel and clinical phenotypes. J. Biol. Chem. 276:30623-30630.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 30623-30630
-
-
Rivolta, I.1
Abriel, H.2
Tateyama, M.3
Liu, H.4
Memmi, M.5
Vardas, P.6
Napolitano, C.7
Priori, S.G.8
Kass, R.S.9
-
31
-
-
0037015190
-
A novel SCN5A mutation associated with long QT-3: Altered inactivation kinetics and channel dysfunction
-
Rivolta, I., C. E. Clancy, M. Tateyama, H. Liu, S. G. Priori, and R. S. Kass. 2002. A novel SCN5A mutation associated with long QT-3: altered inactivation kinetics and channel dysfunction. Physiol. Genomics. 10:191-197.
-
(2002)
Physiol. Genomics
, vol.10
, pp. 191-197
-
-
Rivolta, I.1
Clancy, C.E.2
Tateyama, M.3
Liu, H.4
Priori, S.G.5
Kass, R.S.6
-
32
-
-
0035853854
-
An internalization signal in ClC-5, an endosomal Cl-channel mutated in dent's disease
-
Schwake, M., T. Friedrich, and T. J. Jentsch. 2001. An internalization signal in ClC-5, an endosomal Cl-channel mutated in dent's disease. J. Biol. Chem. 276:12049-12054.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 12049-12054
-
-
Schwake, M.1
Friedrich, T.2
Jentsch, T.J.3
-
34
-
-
0024368695
-
Structural parts involved in activation and inactivation of the sodium channel
-
Stuhmer, W., F. Conti, H. Suzuki, X. Wang, M. Noda, N. Yahagi, H. Kubo, and S. Numa. 1989. Structural parts involved in activation and inactivation of the sodium channel. Nature (Lond.). 339:597-603.
-
(1989)
Nature (Lond.)
, vol.339
, pp. 597-603
-
-
Stuhmer, W.1
Conti, F.2
Suzuki, H.3
Wang, X.4
Noda, M.5
Yahagi, N.6
Kubo, H.7
Numa, S.8
-
35
-
-
0023784649
-
Identification of an intracellular peptide segment involved in sodium channel inactivation
-
Vassilev, P. M., T. Scheuer, and W. A. Catterall. 1988. Identification of an intracellular peptide segment involved in sodium channel inactivation. Science. 241:1658-1661.
-
(1988)
Science
, vol.241
, pp. 1658-1661
-
-
Vassilev, P.M.1
Scheuer, T.2
Catterall, W.A.3
-
36
-
-
0008453646
-
Inhibition of inactivation of single sodium channels by a site-directed antibody
-
Vassilev, P., T. Scheuer, and W. A. Catterall. 1989. Inhibition of inactivation of single sodium channels by a site-directed antibody. Proc. Natl. Acad. Sci. USA. 86:8147-8151.
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 8147-8151
-
-
Vassilev, P.1
Scheuer, T.2
Catterall, W.A.3
-
37
-
-
0034640093
-
Two distinct congenital arrhythmias evoked by a multidysfunctional Na(+) channel
-
Veldkamp, M. W., P. C. Viswanathan, C. Bezzina, A. Baartscheer, A. A. Wilde, and J. R. Balser. 2000. Two distinct congenital arrhythmias evoked by a multidysfunctional Na(+) channel. Circ. Res. 86:E91-E97.
-
(2000)
Circ. Res.
, vol.86
-
-
Veldkamp, M.W.1
Viswanathan, P.C.2
Bezzina, C.3
Baartscheer, A.4
Wilde, A.A.5
Balser, J.R.6
-
38
-
-
0034255466
-
Arrhythmogenic mechanism of an LQT-3 mutation of the human heart Na(+) channel alpha-subunit: A computational analysis
-
Wehrens, X. H., H. Abriel, C. Cabo, J. Benhorin, and R. S. Kass. 2000. Arrhythmogenic mechanism of an LQT-3 mutation of the human heart Na(+) channel alpha-subunit: a computational analysis. Circulation. 102:584-590.
-
(2000)
Circulation
, vol.102
, pp. 584-590
-
-
Wehrens, X.H.1
Abriel, H.2
Cabo, C.3
Benhorin, J.4
Kass, R.S.5
-
39
-
-
0033594970
-
Congenital long-QT syndrome caused by a novel mutation in a conserved acidic domain of the cardiac Na+ channel
-
Wei, J., D. W. Wang, M. Alings, F. Fish, M. Wathen, D. M. Roden, and A. L. George, Jr. 1999. Congenital long-QT syndrome caused by a novel mutation in a conserved acidic domain of the cardiac Na+ channel. Circulation. 99:3165-3171.
-
(1999)
Circulation
, vol.99
, pp. 3165-3171
-
-
Wei, J.1
Wang, D.W.2
Alings, M.3
Fish, F.4
Wathen, M.5
Roden, D.M.6
George Jr., A.L.7
-
40
-
-
0026483172
-
A cluster of hydrophobic amino acid residues required for fast Na(+)-channel inactivation
-
West, J. W., D. E. Patton, T. Scheuer, Y. Wang, A. L. Goldin, and W. A. Catterall. 1992. A cluster of hydrophobic amino acid residues required for fast Na(+)-channel inactivation. Proc. Natl. Acad. Sci. USA. 89:10910-10914.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 10910-10914
-
-
West, J.W.1
Patton, D.E.2
Scheuer, T.3
Wang, Y.4
Goldin, A.L.5
Catterall, W.A.6
-
41
-
-
0036948143
-
Structure-dependent sequence alignment for remotely related proteins
-
Yang, A. S. 2002. Structure-dependent sequence alignment for remotely related proteins. Bioinformatics. 18:1658-1665.
-
(2002)
Bioinformatics
, vol.18
, pp. 1658-1665
-
-
Yang, A.S.1
-
42
-
-
0034682881
-
An integrated approach to the analysis and modeling of protein sequences and structures. I. Protein structural alignment and a quantitative measure for protein structural distance
-
Yang, A. S., and B. Honig. 2000. An integrated approach to the analysis and modeling of protein sequences and structures. I. Protein structural alignment and a quantitative measure for protein structural distance. J. Mol. Biol. 301:665-678.
-
(2000)
J. Mol. Biol.
, vol.301
, pp. 665-678
-
-
Yang, A.S.1
Honig, B.2
-
43
-
-
0036952917
-
Local structure-based sequence profile database for local and global protein structure predictions
-
Yang, A. S., and L. Y. Wang. 2002. Local structure-based sequence profile database for local and global protein structure predictions. Bioinformatics. 18:1650-1657.
-
(2002)
Bioinformatics
, vol.18
, pp. 1650-1657
-
-
Yang, A.S.1
Wang, L.Y.2
|