Altered Neuronal Excitability in Cerebellar Granule Cells of Mice Lacking Calretinin

Journal of Neuroscience

Volumn 23, Issue 28, 2003, Pages 9320-9327

  Gall, David ^a   Roussel, Céline ^a   Susa, Isabella ^a   D'Angelo, Egidio ^b,c   Rossi, Paola ^b   Bearzatto, Bertrand ^a   Galas, Marie Christine ^a   Blum, David ^a   Schurmans, Stéphane ^a   Schiffmann, Serge N ^a  

^a UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^b UNIVERSITY OF PAVIA   (Italy)

^c UNIVERSITY OF PARMA   (Italy)

Author keywords

Calcium; Calcium binding protein; Calretinin; Cerebellar granule cell; Excitability; Mathematical model

Indexed keywords

CALCIUM; CALCIUM BINDING PROTEIN; CALRETININ; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID;

ACTION POTENTIAL; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; FEMALE; GENE MUTATION; GRANULE CELL; INFORMATION PROCESSING; MALE; MOTOR COORDINATION; MOUSE; NERVE CONDUCTION; NERVE EXCITABILITY; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PURKINJE CELL;

EID: 0142250836     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.23-28-09320.2003     Document Type: Article

References (39)

1. Aizenman CD, Linden D (2000) Rapid, synaptically driven increase in the intrinsic excitability of cerebellar deep nuclear neurons. Nat Neurosci 3:109-111.
2. Armano S, Rossi P, Taglietti V, D'Angelo E (2000) Long-term potentiation of intrinsic excitability at the mossy fiber-granule cell synapse of rat cerebellum. J Neurosci 20:5208-5216.
3. Baimbridge KG, Celio M, Rogers J (1992) Calcium-binding proteins in the nervous system. Trends Neurosci 15:303-308.
4. Chay TR, Keizer J (1983) Minimal model for membrane oscillations in the pancreatic β-cell. Biophys J 42:181-190.
5. Cheung WY (1980) Calmodulin plays a pivotal role in cellular regulation. Science 207:19-27.
6. D'Angelo E, Rossi P, Taglietti V (1993) Different proportions of N-methyl-D-aspartate and non-N-methyl-D-aspartate receptor currents at the mossy fibre-granule cell synapse of developing rat cerebellum. Neuroscience 53:121-130.
7. D'Angelo E, Filippi GD, Rossi P, Taglietti V (1995) Synaptic excitation of individual rat cerebellar granule cells in situ: evidence for the role of NMDA receptors. J Physiol (Lond) 484:397-413.
8. 2+ action potentials in immature rat cerebellar granule cells in situ. J Neurophysiol 78:1631-1642.
9. D'Angelo E, Filippi GD, Rossi P, Taglietti V (1998) Ionic mechanism of electroresponsiveness in cerebellar granule cells implicates the action of a persistent sodium current. J Neurophysiol 80:493-503.
10. +-dependent mechanism. J Neurosci 21:759-770.
11. Diño MR, Nunzi M, Anelli R, Mugnaini E (2000) Unipolar brush cells of the vestibulo-cerebellum: afferents and targets. In: Cerebellar modules, molecules, morphology and function (Gerrits N, Ruisgrok T, Zeeuw CJD, eds), pp 123-137. Amsterdam: Elsevier.
12. Dieudonné S, Dumoulin A (2000) Serotonin-driven long-range inhibitory connections in the cerebellar cortex. J Neurosci 20:1837-1848.
13. Edmonds B, Reyes R, Schwaller B, Roberts W (2000) Calretinin modifies presynaptic calcium signaling in frog saccular hair cells. Nat Neurosci 80:2521-2537.
14. Fierro L, Llano I (1996) High endogenous calcium buffering in Purkinje cells from rat cerebellar slices. J Physiol (Lond) 496:617-625.
15. Gabbiani F, Mitgaard J, Knoepfel T (1994) Synaptic integration in a model of cerebellar granule cells. J Neurophysiol 72:999-1009.
16. Galas M-C, Chasserot-Golaz S, Dirrig-Grosch W, Bader M (2000) Presence of dynamin syntaxin complexes associated with secretory granules in adrenal chromaffin cells. J Neurochem 75:1511-1519.
17. i in models for bursting in pancreatic β-cells. Biophys J 77:45-53.
18. 2+-buffering and electrical activity in mouse pancreatic β-cells. Biophys J 76:2018-2028.
19. Hack NJ, Wride M, Charters K, Kater S, Parks T (2000) Developmental changes in the subcellular localization of calretinin. J Neurosci 20:RC67.
20. 2+ signaling in dendrites of pyramidal neurons. Biophys J 70:1069-1081.
21. Hodgkin AL, Huxley A (1952) A quantitative description of membrane current and its application to conduction and excitation in nerve. J Physiol (Lond) 117:500-544.
22. Horn R, Marty A (1988) Muscarinic activation of ionic currents measured by a new whole-cell recording method. J Gen Physiol 92:145-159.
23. Ito M (1984) Granule cells. In: The cerebellum and neuronal control, pp 74-93. New York: Raven.
24. Lancaster B, Nicoll R (1987) Properties of two calcium activated hyperpolarizations in rat hippocampal neurones. J Physiol (Lond) 389:187-203.
25. Maex R, Schutter ED (1998) Synchronization of Golgi and granule cell firing in a detailed network of the cerebellar granule cell layer. J Neurophysiol 80:2521-2537.
26. Marini AM, Strauss K, Jacobowitz D (1997) Calretinin containing neurons in rat cerebellar granule cell cultures. Brain Res Bull 42:279-288.
27. Persechini A, Moncrief N, Kretsinger R (1989) The EF-hand family of calcium-modulated proteins. Trends Neurosci 12:462-467.
28. 2+-dependent inactivation of L-type calcium channels. Neuron 22:549-558.
29. 2+ channel depends on calmodulin. Proc Natl Acad Sci USA 96:2435-2438.
30. Résibois A, Rogers J (1992) Calretinin in rat brain: an immunohistological study. Neuroscience 46:101-134.
31. Roberts WM (1993) Spatial calcium buffering in frog saccular hair cells. Nature 363:74-76.
32. Schiffmann S, Cheron G, Lohof A, D'Alcantara P, Meyer M, Parmentier M, Schurmans S (1999) Impaired motor coordination and Purkinje cell excitability in mice lacking calretinin. Proc Natl Acad Sci USA 96:5257-5262.
33. Schurmans S, Schiffmann S, Gurden H, Lemaire M, Lipp H, Schwam V, Pochet R, Imperato A, Bohme G, Parmentier M (1997) Impaired long-term potentiation induction in dentate gyrus of calretinin-deficient mice. Proc Natl Acad Sci USA 94:10415-10420.
34. Silver RA, Traynelis S, Cull-Candy S (1992) Rapid time course of miniature and evoked excitatory currents at cerebellar synapses in situ. Nature 355:163-166.
35. 2+ chelator inhibits spike repolarization in hippocampal neurons. Brain Res 435:387-392.
36. Stuenkel EL (1994) Regulation of intracellular calcium and calcium buffering properties of rat isolated neurohypophysial nerve endings. J Physiol (Lond) 481:251-271.
37. Tatsumi H, Katayama Y (1993) Regulation of the intracellular free calcium concentration in acutely dissociated neurons from rat nucleus basalis. J Physiol (Lond) 464:165-181.
38. Traub RD, Llinas R (1979) Hippocampal pyramidal cells: significance of dendritic ionic conductances for neuronal functioning and epileptogenesis. J Neurophysiol 42:476-496.
39. Zuhlke RD, Pitt G, Deisseroth K, Tsien R, Reuter H (1999) Calmodulin supports both inactivation and facilitation of L-type calcium channels. Nature 399:159-162.