-
1
-
-
0017743723
-
Inactivation of the sodium channel. II. Gating current experiments
-
Armstrong, C. M., and F. Bezanilla. 1977. Inactivation of the sodium channel. II. Gating current experiments. J. Gen. Physiol. 70:567-590.
-
(1977)
J. Gen. Physiol.
, vol.70
, pp. 567-590
-
-
Armstrong, C.M.1
Bezanilla, F.2
-
2
-
-
0015902531
-
Destruction of sodium conductance inactivation in squid axons perfused with pronase
-
Armstrong, C. M., F. Bezanilla, and E. Rojas. 1973. Destruction of sodium conductance inactivation in squid axons perfused with pronase. J. Gen. Physiol. 62:375-391.
-
(1973)
J. Gen. Physiol.
, vol.62
, pp. 375-391
-
-
Armstrong, C.M.1
Bezanilla, F.2
Rojas, E.3
-
3
-
-
0030465187
-
Local anesthetics as effectors of allosteric gating
-
Balser, J. R., H. B. Nuss, D. W. Orias, D. C. Johns, E. Marban, G. F. Tomaselli, and J. H. Lawrence. 1996. Local anesthetics as effectors of allosteric gating. J. Clin. Invest. 98:2874-2886.
-
(1996)
J. Clin. Invest.
, vol.98
, pp. 2874-2886
-
-
Balser, J.R.1
Nuss, H.B.2
Orias, D.W.3
Johns, D.C.4
Marban, E.5
Tomaselli, G.F.6
Lawrence, J.H.7
-
4
-
-
0026768325
-
Blockade of cardiac sodium channels. Competition between the permeant ion and antiarrhythmic drugs
-
Barber, M. J., D. J. Wendt, C. F. Starmer, and A. O. Grant. 1992. Blockade of cardiac sodium channels. Competition between the permeant ion and antiarrhythmic drugs. J. Clin. Invest. 90:368-381.
-
(1992)
J. Clin. Invest.
, vol.90
, pp. 368-381
-
-
Barber, M.J.1
Wendt, D.J.2
Starmer, C.F.3
Grant, A.O.4
-
5
-
-
0020624782
-
Lidocaine block of cardiac sodium channels
-
Bean, B. P., C. J. Cohen, and R. W. Tsien. 1983. Lidocaine block of cardiac sodium channels. J. Gen. Physiol. 81:613-642.
-
(1983)
J. Gen. Physiol.
, vol.81
, pp. 613-642
-
-
Bean, B.P.1
Cohen, C.J.2
Tsien, R.W.3
-
6
-
-
0029946602
-
Adjacent pore-lining residues with sodium channels identified by paired cysteine mutagenesis
-
Benitah, J.-P., G. F. Tomaselli, and E. Marban. 1996. Adjacent pore-lining residues with sodium channels identified by paired cysteine mutagenesis. Proc. Natl. Acad. Sci. USA. 93:7392-7396.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 7392-7396
-
-
Benitah, J.-P.1
Tomaselli, G.F.2
Marban, E.3
-
9
-
-
0020630770
-
Voltage- and time-dependent depression of maximum rate of depolarization of guinea-pig ventricular action potential by two new antiarrhythmic drugs, flecainide and lorcainide
-
Campbell, T. J., and E. M. Vaughan Williams. 1983. Voltage- and time-dependent depression of maximum rate of depolarization of guinea-pig ventricular action potential by two new antiarrhythmic drugs, flecainide and lorcainide. Cardiovasc. Res. 17:251-258.
-
(1983)
Cardiovasc. Res.
, vol.17
, pp. 251-258
-
-
Campbell, T.J.1
Vaughan Williams, E.M.2
-
10
-
-
0023910798
-
+ channel of rabbit cardiac Purkinje fibers
-
+ channel of rabbit cardiac Purkinje fibers. Circ. Res. 63:50-60.
-
(1988)
Circ. Res.
, vol.63
, pp. 50-60
-
-
Carmeliet, E.1
-
11
-
-
0024595645
-
+ channels in guinea-pig ventricular myocytes by the local anesthetic penticainide
-
+ channels in guinea-pig ventricular myocytes by the local anesthetic penticainide. J. Physiol. 409:241-262.
-
(1989)
J. Physiol.
, vol.409
, pp. 241-262
-
-
Carmeliet, E.1
Nilius, B.2
Vereecke, J.3
-
13
-
-
0028946271
-
Effects of intracellular calcium on sodium current density in cultured neonatal rat cardiac cyocytes
-
483.2
-
Chiamvimonvat, N., M. E. Kargacin, R. B. Clark, and H. J. Duff. 1995. Effects of intracellular calcium on sodium current density in cultured neonatal rat cardiac cyocytes. J. Physiol. 483.2:307-318.
-
(1995)
J. Physiol.
, pp. 307-318
-
-
Chiamvimonvat, N.1
Kargacin, M.E.2
Clark, R.B.3
Duff, H.J.4
-
14
-
-
0023698796
-
Evidence for two components of sodium channel block by lidocaine in isolated cardiac myocytes
-
Clarkson, C. W., C. H. Follmer, R. E. Ten Eick, L. M. Hondeghem, and J. Z. Yeh. 1988. Evidence for two components of sodium channel block by lidocaine in isolated cardiac myocytes. Circ. Res. 63:869-878.
-
(1988)
Circ. Res.
, vol.63
, pp. 869-878
-
-
Clarkson, C.W.1
Follmer, C.H.2
Ten Eick, R.E.3
Hondeghem, L.M.4
Yeh, J.Z.5
-
15
-
-
0027247907
-
Voltage-dependent sodium channels
-
Cohen, S. A., and R. L. Barchi. 1993. Voltage-dependent sodium channels. Internat. Rev. Cytol. 137C:55-103.
-
(1993)
Internat. Rev. Cytol.
, vol.137 C
, pp. 55-103
-
-
Cohen, S.A.1
Barchi, R.L.2
-
16
-
-
0016792109
-
Mechanism of frequency-dependent inhibition of sodium currents in frog myelinated nerve by the lidocaine derivative GEA 968
-
Courtney, K. R. 1975. Mechanism of frequency-dependent inhibition of sodium currents in frog myelinated nerve by the lidocaine derivative GEA 968. J. Pharmacol. Exp. Ther. 195:225-236.
-
(1975)
J. Pharmacol. Exp. Ther.
, vol.195
, pp. 225-236
-
-
Courtney, K.R.1
-
17
-
-
0024433878
-
Blockade of rabbit atrial sodium channels by lidocaine: Characterization of continuous and frequency-dependent blocking
-
Gilliam, F. R., C. F. Starmer, and A. O. Grant. 1989. Blockade of rabbit atrial sodium channels by lidocaine: characterization of continuous and frequency-dependent blocking. Circ. Res. 65:723-739.
-
(1989)
Circ. Res.
, vol.65
, pp. 723-739
-
-
Gilliam, F.R.1
Starmer, C.F.2
Grant, A.O.3
-
18
-
-
0027361325
-
+ channels by a quaternary ammonium ion: Catalysis by a transition-intermediate state?
-
+ channels by a quaternary ammonium ion: catalysis by a transition-intermediate state? J. Physiol. 471:319-341.
-
(1993)
J. Physiol.
, vol.471
, pp. 319-341
-
-
Gingrich, K.J.1
Beardsley, D.2
Yue, D.T.3
-
19
-
-
0032079030
-
Multiple pathways regulate the expression of genes encoding sodium channel subunits in developing neurons
-
Giraud, P., G. Alcaraz, F. Jullien, B. Sampo, E. Jover, F. Couraud, and B. Dargent. 1998. Multiple pathways regulate the expression of genes encoding sodium channel subunits in developing neurons. Mol. Brain Res. 56:238-255.
-
(1998)
Mol. Brain Res.
, vol.56
, pp. 238-255
-
-
Giraud, P.1
Alcaraz, G.2
Jullien, F.3
Sampo, B.4
Jover, E.5
Couraud, F.6
Dargent, B.7
-
20
-
-
0002653574
-
Stable expression of the IFM/QQQ inactivation-deficient mutant Na channel in mammalian cells and its block by disopyramide
-
Abstr.
-
Grant, A. O., R. Chandra, and C. Keller. 1998. Stable expression of the IFM/QQQ inactivation-deficient mutant Na channel in mammalian cells and its block by disopyramide. Circulation. 98:55 (Abstr.).
-
(1998)
Circulation
, vol.98
, pp. 55
-
-
Grant, A.O.1
Chandra, R.2
Keller, C.3
-
21
-
-
0024419958
-
Blockade of cardiac sodium channels by lidocaine: Single channel analysis
-
Grant, A. O., M. A. Dietz, F. R. Gilliam, and C. F. Starmer. 1989. Blockade of cardiac sodium channels by lidocaine: single channel analysis. Circ. Res. 65:1247-1262.
-
(1989)
Circ. Res.
, vol.65
, pp. 1247-1262
-
-
Grant, A.O.1
Dietz, M.A.2
Gilliam, F.R.3
Starmer, C.F.4
-
22
-
-
0030473474
-
The role of inactivation in open-channel block of the sodium channel: Studies with inactivation-deficient mutant channels
-
Grant, A. O., J. E. John, V. V. Nesterenko, and C. F. Starmer. 1996. The role of inactivation in open-channel block of the sodium channel: studies with inactivation-deficient mutant channels. Mol. Pharmacol. 50: 1643-1650.
-
(1996)
Mol. Pharmacol.
, vol.50
, pp. 1643-1650
-
-
Grant, A.O.1
John, J.E.2
Nesterenko, V.V.3
Starmer, C.F.4
-
23
-
-
0023176453
-
Mechanisms of closure of cardiac sodium channels in rabbit ventricular myocytes: Single-channel analysis
-
Grant, A. O., and C. F. Starmer. 1987. Mechanisms of closure of cardiac sodium channels in rabbit ventricular myocytes: single-channel analysis. Circ. Res. 60:897-913.
-
(1987)
Circ. Res.
, vol.60
, pp. 897-913
-
-
Grant, A.O.1
Starmer, C.F.2
-
24
-
-
0027383502
-
Kinetics of interaction of disopyramide with the cardiac sodium channel: Fast dissociation from open channels at normal rest potentials
-
Grant, A. O., D. J. Wendt, Y. Zilberter, and C. F. Starmer. 1993. Kinetics of interaction of disopyramide with the cardiac sodium channel: fast dissociation from open channels at normal rest potentials. J. Membr. Biol. 136:199-214.
-
(1993)
J. Membr. Biol.
, vol.136
, pp. 199-214
-
-
Grant, A.O.1
Wendt, D.J.2
Zilberter, Y.3
Starmer, C.F.4
-
28
-
-
0017332486
-
Local anesthetics: Hydrophilic and hydrophobic pathways for the drug-receptor reaction
-
Hille, B. 1977. Local anesthetics: hydrophilic and hydrophobic pathways for the drug-receptor reaction. J. Gen. Physiol. 69:497-515.
-
(1977)
J. Gen. Physiol.
, vol.69
, pp. 497-515
-
-
Hille, B.1
-
29
-
-
0030956162
-
+ channels: Evidence for a trap door mechanism of activation gating
-
+ channels: evidence for a trap door mechanism of activation gating. J. Gen. Physiol. 109:527-535.
-
(1997)
J. Gen. Physiol.
, vol.109
, pp. 527-535
-
-
Holmgren, M.1
Smith, P.L.2
Yellen, G.3
-
30
-
-
0017726385
-
Time- and voltage-dependent interactions of antiarrhythmic drugs with cardiac sodium channels
-
Hondeghem, L. M., and B. G. Katzung. 1977. Time- and voltage-dependent interactions of antiarrhythmic drugs with cardiac sodium channels. Biochim. Biophys. Acta. 472:373-398.
-
(1977)
Biochim. Biophys. Acta
, vol.472
, pp. 373-398
-
-
Hondeghem, L.M.1
Katzung, B.G.2
-
31
-
-
0026318313
-
A source of bias in the analysis of single channel data: Assessing the apparent interaction between channel proteins
-
Hurwitz, J. L., M. A. Dietz, C. F. Starmer, and A. O. Grant. 1991. A source of bias in the analysis of single channel data: assessing the apparent interaction between channel proteins. Comput. Biomed. Res. 24: 584-602.
-
(1991)
Comput. Biomed. Res.
, vol.24
, pp. 584-602
-
-
Hurwitz, J.L.1
Dietz, M.A.2
Starmer, C.F.3
Grant, A.O.4
-
32
-
-
0026717921
-
Disopyramide block of cardiac sodium current after removal of the fast inactivation process in guinea pig ventricular myocytes
-
Koumi, S.-I., R. Sato, I. Hisatome, H. Hayakawa, H. Okumura, and R. Katori. 1992. Disopyramide block of cardiac sodium current after removal of the fast inactivation process in guinea pig ventricular myocytes. J. Phamacol. Exp. Ther. 261:1167-1174.
-
(1992)
J. Phamacol. Exp. Ther.
, vol.261
, pp. 1167-1174
-
-
Koumi, S.-I.1
Sato, R.2
Hisatome, I.3
Hayakawa, H.4
Okumura, H.5
Katori, R.6
-
33
-
-
0028258554
-
+ channels must deactivate to recover from inactivation
-
+ channels must deactivate to recover from inactivation. Neuron. 12:819-829.
-
(1994)
Neuron.
, vol.12
, pp. 819-829
-
-
Kuo, C.-C.1
Bean, B.D.2
-
34
-
-
0029737304
-
Single-channel analysis of inactivation-defective rat skeletal muscle sodium channels containing the F1304Q mutation
-
Lawrence, J. H., D. W. Orias, J. R. Baiser, H. B. Nuss, G. F. Tomaselli, B. O'Rourke, and E. Marban. 1996. Single-channel analysis of inactivation-defective rat skeletal muscle sodium channels containing the F1304Q mutation. Biophys. J. 71:1285-1294.
-
(1996)
Biophys. J.
, vol.71
, pp. 1285-1294
-
-
Lawrence, J.H.1
Orias, D.W.2
Baiser, J.R.3
Nuss, H.B.4
Tomaselli, G.F.5
O'Rourke, B.6
Marban, E.7
-
35
-
-
0028051874
-
Relationship between structure and sodium channel blockade by lidocaine and its amino-alkyl derivatives
-
Liu, L., D. J. Wendt, and A. O. Grant. 1994. Relationship between structure and sodium channel blockade by lidocaine and its amino-alkyl derivatives. J. Cardiovasc. Pharmacol. 24:803-812.
-
(1994)
J. Cardiovasc. Pharmacol.
, vol.24
, pp. 803-812
-
-
Liu, L.1
Wendt, D.J.2
Grant, A.O.3
-
36
-
-
0020646202
-
The charge carried by single-channel currents of rat cultured muscle cells in the presence of local anesthetics
-
Neher, E. 1983. The charge carried by single-channel currents of rat cultured muscle cells in the presence of local anesthetics. J. Physiol. (Lond.). 339:663-678.
-
(1983)
J. Physiol. (Lond.)
, vol.339
, pp. 663-678
-
-
Neher, E.1
-
37
-
-
0026587481
-
States and sites of actions of flecainide on guinea-pig cardiac sodium channels
-
Nitta, J.-I., A. Sunami, F. Marumo, and M. Hiraoka. 1992. States and sites of actions of flecainide on guinea-pig cardiac sodium channels. Eur. J. Pharmacol. 214:191-197.
-
(1992)
Eur. J. Pharmacol.
, vol.214
, pp. 191-197
-
-
Nitta, J.-I.1
Sunami, A.2
Marumo, F.3
Hiraoka, M.4
-
38
-
-
0020635302
-
Voltage- and use-dependent effects of lidocaine on sodium current in rat single ventricular cells
-
Sanchez-Chapula, J., Y. Tsuda, and I. R. Josephson. 1983. Voltage- and use-dependent effects of lidocaine on sodium current in rat single ventricular cells. Circ. Res. 52:557-565.
-
(1983)
Circ. Res.
, vol.52
, pp. 557-565
-
-
Sanchez-Chapula, J.1
Tsuda, Y.2
Josephson, I.R.3
-
39
-
-
0022409621
-
Phasic ion channel blockade: A kinetic and parameter estimation procedure
-
Starmer, C. F., and A. O. Grant. 1985. Phasic ion channel blockade: a kinetic and parameter estimation procedure. Mol. Pharmacol. 28: 348-356.
-
(1985)
Mol. Pharmacol.
, vol.28
, pp. 348-356
-
-
Starmer, C.F.1
Grant, A.O.2
-
40
-
-
0026016004
-
Lidocaine blockade of continuously and transiently accessible sites in cardiac sodium channels
-
Starmer, C. F., V. V. Nesterenko, A. I. Undrovinas, A. O. Grant, and L. V. Rosenshtraukh. 1991. Lidocaine blockade of continuously and transiently accessible sites in cardiac sodium channels. J. Mol. Cell Cardiol. 23(Suppl 1):73-83.
-
(1991)
J. Mol. Cell Cardiol.
, vol.23
, Issue.1 SUPPL.
, pp. 73-83
-
-
Starmer, C.F.1
Nesterenko, V.V.2
Undrovinas, A.I.3
Grant, A.O.4
Rosenshtraukh, L.V.5
-
41
-
-
0015784454
-
The inhibition of sodium currents in myelinated nerve by quaternary derivatives of lidocaine
-
Strichartz, G. R. 1973. The inhibition of sodium currents in myelinated nerve by quaternary derivatives of lidocaine. J. Gen. Physiol. 62:37-57.
-
(1973)
J. Gen. Physiol.
, vol.62
, pp. 37-57
-
-
Strichartz, G.R.1
-
42
-
-
0026102138
-
+ current by disopyramide and lidocaine in guinea-pig ventricular myocytes
-
+ current by disopyramide and lidocaine in guinea-pig ventricular myocytes. Circ. Res. 68:653-661.
-
(1991)
Circ. Res.
, vol.68
, pp. 653-661
-
-
Sunami, A.1
Fan, Z.2
Nitta, J.-I.3
Hiraoka, M.4
-
44
-
-
0023272484
-
Inhibition of sodium currents by local anesthetics in chloramine-T-treated squid axons
-
Wang, G. K., M. S. Brodwick, and D. C. Eaton. 1987. Inhibition of sodium currents by local anesthetics in chloramine-T-treated squid axons. J. Gen. Physiol. 89:645-667.
-
(1987)
J. Gen. Physiol.
, vol.89
, pp. 645-667
-
-
Wang, G.K.1
Brodwick, M.S.2
Eaton, D.C.3
-
45
-
-
0027265793
-
+ channels by batrachotoxin: Effects on gating, kinetics, and local anesthetic binding
-
+ channels by batrachotoxin: effects on gating, kinetics, and local anesthetic binding. Biophys. J. 65:386-395.
-
(1993)
Biophys. J.
, vol.65
, pp. 386-395
-
-
Wasserstrom, J.A.1
Liberty, K.2
Kelly, J.3
Santucci, P.4
Myers, M.5
-
47
-
-
0023079101
-
Molecular and structural basis of resting and use-dependent block of sodium current defined using disopyramide analogues
-
Yeh, J. Z., and R. Ten-Eick. 1987. Molecular and structural basis of resting and use-dependent block of sodium current defined using disopyramide analogues. Biophys. J. 51:123-135.
-
(1987)
Biophys. J.
, vol.51
, pp. 123-135
-
-
Yeh, J.Z.1
Ten-Eick, R.2
-
48
-
-
0021666771
-
The role of inactivation in the cumulative blockage of voltage-dependent sodium channels by local anesthetics and antiarrhythmics
-
Zaborovskaya, L. D., and B. I. Khodorov. 1984. The role of inactivation in the cumulative blockage of voltage-dependent sodium channels by local anesthetics and antiarrhythmics. Gen. Physiol. Biophys. 3:517-520.
-
(1984)
Gen. Physiol. Biophys.
, vol.3
, pp. 517-520
-
-
Zaborovskaya, L.D.1
Khodorov, B.I.2
-
49
-
-
0028357213
-
Sodium channel blockade: Multiple rest states revealed by channel interactions with disopyramide and quinidine
-
Zilberter, Y. I., C. F. Starmer, and A. O. Grant. 1994. Sodium channel blockade: multiple rest states revealed by channel interactions with disopyramide and quinidine. Am. J. Physiol. Heart Circ. Physiol. 266: H2007-H2017.
-
(1994)
Am. J. Physiol. Heart Circ. Physiol.
, vol.266
-
-
Zilberter, Y.I.1
Starmer, C.F.2
Grant, A.O.3
|