PTPN2 gene variants are associated with susceptibility to both Crohn's disease and ulcerative colitis supporting a common genetic disease background

PLoS ONE

Volumn 7, Issue 3, 2012, Pages

  Glas, Jürgen ^a,b,c   Wagner, Johanna ^a,b   Seiderer, Julia ^a   Olszak, Torsten ^a,d   Wetzke, Martin ^a,b,e   Beigel, Florian ^a   Tillack, Cornelia ^a   Stallhofer, Johannes ^a   Friedrich, Matthias ^a,b   Steib, Christian ^a   Göke, Burkhard ^a   Ochsenkühn, Thomas ^a   Karbalai, Nazanin ^f   Diegelmann, Julia ^a,b   Czamara, Darina ^f   Brand, Stephan ^a  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b UNIVERSITY OF MUNICH   (Germany)

^c RWTH AACHEN UNIVERSITY   (Germany)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

^e HANNOVER MEDICAL SCHOOL   (Germany)

^f MAX PLANCK INSTITUTE OF PSYCHIATRY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN; HEAT SHOCK TRANSCRIPTION FACTOR 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; STEROL REGULATORY ELEMENT BINDING PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GATA 1; TRANSCRIPTION FACTOR GATA 2; TRANSCRIPTION FACTOR GATA 3; UNCLASSIFIED DRUG; NON RECEPTOR PROTEIN TYROSINE PHOSPHATASE 2; PTPN2 PROTEIN, HUMAN;

ADOLESCENT; ADULT; AGED; ARTICLE; ATG16L1 GENE; BINDING SITE; CHILD; COHORT ANALYSIS; CONTROLLED STUDY; CROHN DISEASE; FEMALE; GENE; GENE FREQUENCY; GENE FUNCTION; GENE INTERACTION; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC EPISTASIS; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOTYPE PHENOTYPE CORRELATION; HAPLOTYPE; HUMAN; IL23R GENE; IMMUNE RESPONSE; MAJOR CLINICAL STUDY; MALE; NOD2 GENE; PRESCHOOL CHILD; PROTEIN BINDING; PTPN2 GENE; SCHOOL CHILD; SINGLE NUCLEOTIDE POLYMORPHISM; ULCERATIVE COLITIS; GENETIC PREDISPOSITION; GENETICS; GENOTYPE; MIDDLE AGED; PHENOTYPE;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; COLITIS, ULCERATIVE; CROHN DISEASE; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HAPLOTYPES; HUMANS; MALE; MIDDLE AGED; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 2; YOUNG ADULT;

EID: 84858642947     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0033682     Document Type: Article

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