-
1
-
-
34547176642
-
Unravelling the pathogenesis of inflammatory bowel disease
-
Xavier RJ, Podolsky DK, (2007) Unravelling the pathogenesis of inflammatory bowel disease. Nature 448: 427-434.
-
(2007)
Nature
, vol.448
, pp. 427-434
-
-
Xavier, R.J.1
Podolsky, D.K.2
-
2
-
-
38649115342
-
Microbial influences in inflammatory bowel diseases
-
Sartor RB, (2008) Microbial influences in inflammatory bowel diseases. Gastroenterology 134: 577-594.
-
(2008)
Gastroenterology
, vol.134
, pp. 577-594
-
-
Sartor, R.B.1
-
3
-
-
48349136889
-
Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease
-
Barrett JC, Hansoul S, Nicolae DL, Cho JH, Duerr RH, et al. (2008) Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease. Nat Genet 40: 955-26.
-
(2008)
Nat Genet
, vol.40
, pp. 926-955
-
-
Barrett, J.C.1
Hansoul, S.2
Nicolae, D.L.3
Cho, J.H.4
Duerr, R.H.5
-
4
-
-
79952195585
-
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47
-
Anderson CA, Boucher G, Lees CW, Franke A, D'Amato M, et al. (2011) Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47. Nat Genet 43: 246-52.
-
(2011)
Nat Genet
, vol.43
, pp. 246-252
-
-
Anderson, C.A.1
Boucher, G.2
Lees, C.W.3
Franke, A.4
D'Amato, M.5
-
5
-
-
78649489009
-
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
-
Franke A, McGovern DP, Barrett JC, Wang K, Radford-Smith GL, et al. (2010) Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. Nat Genet 42: 1118-25.
-
(2010)
Nat Genet
, vol.42
, pp. 1118-1125
-
-
Franke, A.1
McGovern, D.P.2
Barrett, J.C.3
Wang, K.4
Radford-Smith, G.L.5
-
6
-
-
84969213492
-
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
-
Wellcome Trust Case Control Consortium
-
Wellcome Trust Case Control Consortium (2007) Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 47: 61-87.
-
(2007)
Nature
, vol.47
, pp. 61-87
-
-
-
7
-
-
44349173654
-
Replication of signals from recent studies of Crohn's disease identifies previously unknown disease loci for ulcerative colitis
-
Franke A, Balschun T, Karlsen TH, Hedderich J, May S, et al. (2008) Replication of signals from recent studies of Crohn's disease identifies previously unknown disease loci for ulcerative colitis. Nat Genet 40: 713-5.
-
(2008)
Nat Genet
, vol.40
, pp. 713-715
-
-
Franke, A.1
Balschun, T.2
Karlsen, T.H.3
Hedderich, J.4
May, S.5
-
8
-
-
59749094752
-
TNFSF15 polymorphisms are associated with susceptibility to inflammatory bowel disease in a new European cohort
-
Thiébaut R, Kotti S, Jung C, Merlin F, Colombel JF, et al. (2009) TNFSF15 polymorphisms are associated with susceptibility to inflammatory bowel disease in a new European cohort. Am J Gastroenterol 104: 384-91.
-
(2009)
Am J Gastroenterol
, vol.104
, pp. 384-391
-
-
Thiébaut, R.1
Kotti, S.2
Jung, C.3
Merlin, F.4
Colombel, J.F.5
-
9
-
-
59149087627
-
Ulcerative colitis-risk loci on chromosomes 1p36 and 12q15 found by genome-wide association study
-
Silverberg MS, Cho JH, Rioux JD, McGovern DP, Wu J, et al. (2009) Ulcerative colitis-risk loci on chromosomes 1p36 and 12q15 found by genome-wide association study. Nat Genet 41: 216-20.
-
(2009)
Nat Genet
, vol.41
, pp. 216-220
-
-
Silverberg, M.S.1
Cho, J.H.2
Rioux, J.D.3
McGovern, D.P.4
Wu, J.5
-
10
-
-
52949091918
-
Loci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel disease
-
Kugathasan S, Baldassano RN, Bradfield JP, Sleiman PM, Imielinski M, et al. (2008) Loci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel disease. Nat Genet 40: 1211-1215.
-
(2008)
Nat Genet
, vol.40
, pp. 1211-1215
-
-
Kugathasan, S.1
Baldassano, R.N.2
Bradfield, J.P.3
Sleiman, P.M.4
Imielinski, M.5
-
11
-
-
0037043658
-
Inflammatory bowel disease
-
Podolsky DK, (2002) Inflammatory bowel disease. N Engl J Med 347: 417-29.
-
(2002)
N Engl J Med
, vol.347
, pp. 417-429
-
-
Podolsky, D.K.1
-
12
-
-
84894353884
-
Toward an integrated clinical, molecular and serological classification of inflammatory bowel disease: Report of a Working Party of the 2005 Montreal World Congress of Gastroenterology
-
Silverberg MS, Satsangi J, Ahmad T, Arnott ID, Bernstein CN, et al. (2005) Toward an integrated clinical, molecular and serological classification of inflammatory bowel disease: Report of a Working Party of the 2005 Montreal World Congress of Gastroenterology. Can J Gastroenterol 19 (Suppl A): 5-36.
-
(2005)
Can J Gastroenterol
, vol.19
, Issue.SUPPL. A
, pp. 5-36
-
-
Silverberg, M.S.1
Satsangi, J.2
Ahmad, T.3
Arnott, I.D.4
Bernstein, C.N.5
-
13
-
-
22044445381
-
Inflammatory bowel disease in children and adolescents: recommendations for diagnosis-the Porto criteria
-
IBD Working Group of the European Society for Paediatric Gastroenterology, Hepatology and Nutrition
-
IBD Working Group of the European Society for Paediatric Gastroenterology, Hepatology and Nutrition (2005) Inflammatory bowel disease in children and adolescents: recommendations for diagnosis-the Porto criteria. J Pediatr Gastroenterol Nutr 41: 1-7.
-
(2005)
J Pediatr Gastroenterol Nutr
, vol.41
, pp. 1-7
-
-
-
14
-
-
0028267896
-
Frequency of glucocorticoid resistance and dependency in Crohn's disease
-
Munkholm P, Langholz E, Davidsen M, Binder V, (1994) Frequency of glucocorticoid resistance and dependency in Crohn's disease. Gut 35: 360-2.
-
(1994)
Gut
, vol.35
, pp. 360-362
-
-
Munkholm, P.1
Langholz, E.2
Davidsen, M.3
Binder, V.4
-
15
-
-
0034903792
-
The natural history of corticosteroid therapy for inflammatory bowel disease: a population-based study
-
Faubion WA Jr, Loftus EV Jr, Harmsen WS, Zinsmeister AR, Sandborn WJ, (2001) The natural history of corticosteroid therapy for inflammatory bowel disease: a population-based study. Gastroenterology 121: 255-60.
-
(2001)
Gastroenterology
, vol.121
, pp. 255-260
-
-
Faubion Jr., W.A.1
Loftus Jr., E.V.2
Harmsen, W.S.3
Zinsmeister, A.R.4
Sandborn, W.J.5
-
16
-
-
70649113728
-
Common variants at five new loci associated with early-onset inflammatory bowel disease
-
Imielinski M, Baldassano RN, Griffiths A, Russell RK, Annese V, et al. (2009) Common variants at five new loci associated with early-onset inflammatory bowel disease. Nat Genet 41: 1335-1340.
-
(2009)
Nat Genet
, vol.41
, pp. 1335-1340
-
-
Imielinski, M.1
Baldassano, R.N.2
Griffiths, A.3
Russell, R.K.4
Annese, V.5
-
17
-
-
70649103789
-
Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region
-
The UK IBD Genetics Consortium, the Wellcome Trust Case Control Consortium 2
-
The UK IBD Genetics Consortium, the Wellcome Trust Case Control Consortium 2, (2009) Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region. Nat Genet 12: 1330-1334.
-
(2009)
Nat Genet
, vol.12
, pp. 1330-1334
-
-
-
18
-
-
77950298959
-
Genome-wide association identifies multiple ulcerative colitis susceptibility loci
-
McGovern DP, Gardet A, Törkvist L, Goyette P, Essers J, et al. (2010) Genome-wide association identifies multiple ulcerative colitis susceptibility loci. Nat Genet 42: 332-7.
-
(2010)
Nat Genet
, vol.42
, pp. 332-337
-
-
McGovern, D.P.1
Gardet, A.2
Törkvist, L.3
Goyette, P.4
Essers, J.5
-
19
-
-
72049130560
-
Investigation of Reported Associations Between the 20q13 and 21q22 Loci and Pediatric-Onset Crohn's Disease in Canadian Children
-
Amre DK, Mack DR, Morgan K, Fujiwara M, Israel D, et al. (2009) Investigation of Reported Associations Between the 20q13 and 21q22 Loci and Pediatric-Onset Crohn's Disease in Canadian Children. Am J Gastroenterol 104: 2824-8.
-
(2009)
Am J Gastroenterol
, vol.104
, pp. 2824-2828
-
-
Amre, D.K.1
Mack, D.R.2
Morgan, K.3
Fujiwara, M.4
Israel, D.5
-
20
-
-
27944464550
-
Single nucleotide polymorphisms in TNFSF15 confer susceptibility to Crohn's disease
-
Yamazaki K, McGovern D, Ragoussis J, Paolucci M, Butler H, et al. (2005) Single nucleotide polymorphisms in TNFSF15 confer susceptibility to Crohn's disease. Hum Mol Genet 14: 3499-3506.
-
(2005)
Hum Mol Genet
, vol.14
, pp. 3499-3506
-
-
Yamazaki, K.1
McGovern, D.2
Ragoussis, J.3
Paolucci, M.4
Butler, H.5
-
21
-
-
46049089270
-
Contribution of TNFSF15 gene variants to Crohn's disease susceptibility confirmed in UK population
-
Tremelling M, Berzuini C, Massey D, Bredin F, Price C, et al. (2008) Contribution of TNFSF15 gene variants to Crohn's disease susceptibility confirmed in UK population. Inflamm Bowel Dis 14: 733-7.
-
(2008)
Inflamm Bowel Dis
, vol.14
, pp. 733-737
-
-
Tremelling, M.1
Berzuini, C.2
Massey, D.3
Bredin, F.4
Price, C.5
-
22
-
-
36749055773
-
TNFSF15 is an ethnic-specific IBD gene
-
Picornell Y, Mei L, Taylor K, Yang H, Targan SR, et al. (2007) TNFSF15 is an ethnic-specific IBD gene. Inflamm Bowel Dis 13: 1333-1338.
-
(2007)
Inflamm Bowel Dis
, vol.13
, pp. 1333-1338
-
-
Picornell, Y.1
Mei, L.2
Taylor, K.3
Yang, H.4
Targan, S.R.5
-
23
-
-
44949240320
-
Association of TNFSF15 with Crohn's disease in Koreans
-
Yang SK, Lim J, Chang HS, Lee I, Li Y, et al. (2008) Association of TNFSF15 with Crohn's disease in Koreans. Am J Gastroenterol 103: 1437-42.
-
(2008)
Am J Gastroenterol
, vol.103
, pp. 1437-1442
-
-
Yang, S.K.1
Lim, J.2
Chang, H.S.3
Lee, I.4
Li, Y.5
-
24
-
-
18344385475
-
TL1A is a TNF-like ligand for DR3 and TR6/DcR3 and functions as a T cell costimulator
-
Migone TS, Zhang J, Luo X, Zhuang L, Chen C, et al. (2002) TL1A is a TNF-like ligand for DR3 and TR6/DcR3 and functions as a T cell costimulator. Immunity 16: 479-92.
-
(2002)
Immunity
, vol.16
, pp. 479-492
-
-
Migone, T.S.1
Zhang, J.2
Luo, X.3
Zhuang, L.4
Chen, C.5
-
25
-
-
2942652655
-
Potential role for TL1A, the new TNF-family member and potent costimulator of IFN-gamma, in mucosal inflammation
-
Prehn JL, Mehdizadeh S, Landers CJ, Luo X, Cha SC, et al. (2004) Potential role for TL1A, the new TNF-family member and potent costimulator of IFN-gamma, in mucosal inflammation. Clin Immunol 112: 66-77.
-
(2004)
Clin Immunol
, vol.112
, pp. 66-77
-
-
Prehn, J.L.1
Mehdizadeh, S.2
Landers, C.J.3
Luo, X.4
Cha, S.C.5
-
26
-
-
34347338690
-
Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility
-
Parkes M, Barrett JC, Prescott NJ, Tremelling M, Anderson CA, et al. (2007) Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility. Nat Genet 39: 830-2.
-
(2007)
Nat Genet
, vol.39
, pp. 830-832
-
-
Parkes, M.1
Barrett, J.C.2
Prescott, N.J.3
Tremelling, M.4
Anderson, C.A.5
-
27
-
-
44349136821
-
Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease
-
Fisher SA, Tremelling M, Anderson CA, Gwilliam R, Bumpstead S, et al. (2008) Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease. Nat Genet 40: 710-2.
-
(2008)
Nat Genet
, vol.40
, pp. 710-712
-
-
Fisher, S.A.1
Tremelling, M.2
Anderson, C.A.3
Gwilliam, R.4
Bumpstead, S.5
-
28
-
-
0343570496
-
NKX2.3 is required for MAdCAM-1 expression and homing of lymphocytes in spleen and mucosa-associated lymphoid tissue
-
Pabst O, Förster R, Lipp M, Engel H, Arnold HH, (2000) NKX2.3 is required for MAdCAM-1 expression and homing of lymphocytes in spleen and mucosa-associated lymphoid tissue. EMBO J 2: 2015-23.
-
(2000)
EMBO J
, vol.2
, pp. 2015-2023
-
-
Pabst, O.1
Förster, R.2
Lipp, M.3
Engel, H.4
Arnold, H.H.5
-
29
-
-
34347341846
-
Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes
-
Todd JA, Walker NM, Cooper JD, Smyth DJ, Downes K, et al. (2007) Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes. Nat Genet 7: 857-64.
-
(2007)
Nat Genet
, vol.7
, pp. 857-864
-
-
Todd, J.A.1
Walker, N.M.2
Cooper, J.D.3
Smyth, D.J.4
Downes, K.5
-
30
-
-
62049085384
-
Confirmation of multiple Crohn's disease susceptibility loci in a large Dutch-Belgian cohort
-
Weersma RK, Stokkers PC, Cleynen I, Wolfkamp SC, Henckaerts L, et al. (2009) Confirmation of multiple Crohn's disease susceptibility loci in a large Dutch-Belgian cohort. Am J Gastroenterol 104: 630-8.
-
(2009)
Am J Gastroenterol
, vol.104
, pp. 630-638
-
-
Weersma, R.K.1
Stokkers, P.C.2
Cleynen, I.3
Wolfkamp, S.C.4
Henckaerts, L.5
-
31
-
-
77951782697
-
Susceptibility loci reported in genome-wide association studies are associated with Crohn's disease in Canadian children
-
Amre DK, Mack DR, Morgan K, Israel D, Deslandres C, et al. (2010) Susceptibility loci reported in genome-wide association studies are associated with Crohn's disease in Canadian children. Aliment Pharmacol Ther 31: 1186-91.
-
(2010)
Aliment Pharmacol Ther
, vol.31
, pp. 1186-1191
-
-
Amre, D.K.1
Mack, D.R.2
Morgan, K.3
Israel, D.4
Deslandres, C.5
-
32
-
-
0030007093
-
Contribution of genes of the major histocompatibility complex to susceptibility and disease phenotype in inflammatory bowel disease
-
Satsangi J, Welsh KI, Bunce M, Julier C, Farrant JM, et al. (1996) Contribution of genes of the major histocompatibility complex to susceptibility and disease phenotype in inflammatory bowel disease. Lancet 4: 1212-7.
-
(1996)
Lancet
, vol.4
, pp. 1212-1217
-
-
Satsangi, J.1
Welsh, K.I.2
Bunce, M.3
Julier, C.4
Farrant, J.M.5
-
33
-
-
0033910870
-
Genomewide search in Canadian families with inflammatory bowel disease reveals two novel susceptibility loci
-
Rioux JD, Silverberg MS, Daly MJ, Steinhart AH, McLeod RS, et al. (2000) Genomewide search in Canadian families with inflammatory bowel disease reveals two novel susceptibility loci. Am J Hum Genet 66: 1863-70.
-
(2000)
Am J Hum Genet
, vol.66
, pp. 1863-1870
-
-
Rioux, J.D.1
Silverberg, M.S.2
Daly, M.J.3
Steinhart, A.H.4
McLeod, R.S.5
-
34
-
-
73249122274
-
Mapping of multiple susceptibility variants within the MHC region for 7 immune-mediated diseases
-
International MHC and Autoimmunity Genetics Network
-
International MHC and Autoimmunity Genetics Network, Rioux JD, Goyette P, Vyse TJ, Hammarström L, et al. (2009) Mapping of multiple susceptibility variants within the MHC region for 7 immune-mediated diseases. Proc Natl Acad Sci U S A 106: 18680-5.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 18680-18685
-
-
Rioux, J.D.1
Goyette, P.2
Vyse, T.J.3
Hammarström, L.4
-
35
-
-
44349136821
-
Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease
-
Fisher SA, Tremelling M, Anderson CA, Gwilliam R, Bumpstead S, et al. (2008) Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease. Nat Genet 40: 710-2.
-
(2008)
Nat Genet
, vol.40
, pp. 710-712
-
-
Fisher, S.A.1
Tremelling, M.2
Anderson, C.A.3
Gwilliam, R.4
Bumpstead, S.5
-
36
-
-
55049111426
-
Sequence variants in IL10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility
-
Franke A, Balschun T, Karlsen TH, Sventoraityte J, Nikolaus S, et al. (2008) Sequence variants in IL10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility. Nat Genet 40: 1319-23.
-
(2008)
Nat Genet
, vol.40
, pp. 1319-1323
-
-
Franke, A.1
Balschun, T.2
Karlsen, T.H.3
Sventoraityte, J.4
Nikolaus, S.5
-
37
-
-
70649086082
-
A genome-wide association study identifies three new susceptibility loci for ulcerative colitis in the Japanese population
-
Asano K, Matsushita T, Umeno J, Hosono N, Takahashi A, et al. (2009) A genome-wide association study identifies three new susceptibility loci for ulcerative colitis in the Japanese population. Nat Genet 41: 1325-9.
-
(2009)
Nat Genet
, vol.41
, pp. 1325-1329
-
-
Asano, K.1
Matsushita, T.2
Umeno, J.3
Hosono, N.4
Takahashi, A.5
-
38
-
-
34247579326
-
Novel Crohn disease locus identified by genome-wide association maps to a gene desert on 5p13.1 and modulates expression of PTGER4
-
Libioulle C, Louis E, Hansoul S, Sandor C, Farnir F, et al. (2007) Novel Crohn disease locus identified by genome-wide association maps to a gene desert on 5p13.1 and modulates expression of PTGER4. PLoS Genet 3: e58.
-
(2007)
PLoS Genet
, vol.3
-
-
Libioulle, C.1
Louis, E.2
Hansoul, S.3
Sandor, C.4
Farnir, F.5
-
39
-
-
34247554965
-
Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis
-
Rioux JD, Xavier RJ, Taylor KD, Silverberg MS, Goyette P, et al. (2007) Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis. Nat Genet 39: 596-604.
-
(2007)
Nat Genet
, vol.39
, pp. 596-604
-
-
Rioux, J.D.1
Xavier, R.J.2
Taylor, K.D.3
Silverberg, M.S.4
Goyette, P.5
-
40
-
-
70349974546
-
Established genetic risk factors do not distinguish early and later onset Crohn's disease
-
Essers JB, Lee JJ, Kugathasan S, Stevens CR, Grand RJ, et al. (2009) Established genetic risk factors do not distinguish early and later onset Crohn's disease. Inflamm Bowel Dis 15: 1508-14.
-
(2009)
Inflamm Bowel Dis
, vol.15
, pp. 1508-1514
-
-
Essers, J.B.1
Lee, J.J.2
Kugathasan, S.3
Stevens, C.R.4
Grand, R.J.5
|