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Volumn 160, Issue 4, 2012, Pages

Which neuroprotective agents are ready for bench to bedside translation in the newborn infant?

Author keywords

[No Author keywords available]

Indexed keywords

7 NITROINDAZOLE; ACETYLCYSTEINE; ALLOPURINOL; ALPHA TOCOPHEROL; ASCORBIC ACID; DEHYDROASCORBIC ACID; ERYTHROPOIETIN; HJ 619; IMIDAZOLE; JI 8; MELATONIN; NITRIC OXIDE SYNTHASE INHIBITOR; TETRAHYDROBIOPTERIN; UNCLASSIFIED DRUG; XENON;

EID: 84858337595     PISSN: 00223476     EISSN: 10976833     Source Type: Journal    
DOI: 10.1016/j.jpeds.2011.12.052     Document Type: Note
Times cited : (140)

References (158)
  • 1
    • 77954315863 scopus 로고    scopus 로고
    • Epidemiology of neonatal encephalopathy and hypoxic-ischaemic encephalopathy
    • J. Kurinczuk, M. White-Koning, and N. Badawi Epidemiology of neonatal encephalopathy and hypoxic-ischaemic encephalopathy Early Hum Dev 86 2010 329 338
    • (2010) Early Hum Dev , vol.86 , pp. 329-338
    • Kurinczuk, J.1    White-Koning, M.2    Badawi, N.3
  • 2
    • 24044548649 scopus 로고    scopus 로고
    • Neuropsychological and educational problems at school age associated with neonatal encephalopathy
    • N. Marlow, A. Rose, C. Rands, and E.S. Draper Neuropsychological and educational problems at school age associated with neonatal encephalopathy Arch Dis Child Fetal Neonatal Ed 90 2005 F380 F387
    • (2005) Arch Dis Child Fetal Neonatal Ed , vol.90
    • Marlow, N.1    Rose, A.2    Rands, C.3    Draper, E.S.4
  • 3
    • 0024602050 scopus 로고
    • School performance of survivors of neonatal encephalopathy associated with birth asphyxia at term
    • C.M. Robertson, N.N. Finer, and M.G. Grace School performance of survivors of neonatal encephalopathy associated with birth asphyxia at term J Pediatr 114 1989 753 760
    • (1989) J Pediatr , vol.114 , pp. 753-760
    • Robertson, C.M.1    Finer, N.N.2    Grace, M.G.3
  • 4
    • 77149149663 scopus 로고    scopus 로고
    • Neurological outcomes at 18 months of age after moderate hypothermia for perinatal hypoxic ischaemic encephalopathy: Synthesis and meta-analysis of trial data
    • A. Edwards, P. Brocklehurst, A. Gunn, H. Halliday, E. Juszczak, and M. Levene Neurological outcomes at 18 months of age after moderate hypothermia for perinatal hypoxic ischaemic encephalopathy: synthesis and meta-analysis of trial data BMJ 340 2010 C363
    • (2010) BMJ , vol.340 , pp. 363
    • Edwards, A.1    Brocklehurst, P.2    Gunn, A.3    Halliday, H.4    Juszczak, E.5    Levene, M.6
  • 5
    • 13844321255 scopus 로고    scopus 로고
    • Selective head cooling with mild systemic hypothermia after neonatal encephalopathy: Multicentre randomised trial
    • P. Gluckman, J. Wyatt, D. Azzopardi, R. Ballard, A. Edwards, and D. Ferriero Selective head cooling with mild systemic hypothermia after neonatal encephalopathy: multicentre randomised trial Lancet 365 2005 663 670
    • (2005) Lancet , vol.365 , pp. 663-670
    • Gluckman, P.1    Wyatt, J.2    Azzopardi, D.3    Ballard, R.4    Edwards, A.5    Ferriero, D.6
  • 6
    • 77954311938 scopus 로고    scopus 로고
    • Experimental treatments for hypoxic ischaemic encephalopathy
    • D. Kelen, and N.J. Robertson Experimental treatments for hypoxic ischaemic encephalopathy Early Hum Dev 86 2010 369 377
    • (2010) Early Hum Dev , vol.86 , pp. 369-377
    • Kelen, D.1    Robertson, N.J.2
  • 7
    • 77955982977 scopus 로고    scopus 로고
    • Synergistic neuroprotective therapies with hypothermia
    • M. Cilio, and D. Ferriero Synergistic neuroprotective therapies with hypothermia Semin Fetal Neonatal Med 15 2010 293 298
    • (2010) Semin Fetal Neonatal Med , vol.15 , pp. 293-298
    • Cilio, M.1    Ferriero, D.2
  • 8
    • 0026611041 scopus 로고
    • Protection against hippocampal CA1 cell loss by post-ischaemic hypothermia is dependent on delay of initiation and duration
    • M. Carroll, and O. Beek Protection against hippocampal CA1 cell loss by post-ischaemic hypothermia is dependent on delay of initiation and duration Metab Brain Dis 7 1992 45 50
    • (1992) Metab Brain Dis , vol.7 , pp. 45-50
    • Carroll, M.1    Beek, O.2
  • 9
    • 0031789208 scopus 로고    scopus 로고
    • Neuroprotection with prolonged head cooling started before postischemic seizures in fetal sheep
    • A. Gunn, T. Gunn, M. Gunning, C. Williams, and P. Gluckman Neuroprotection with prolonged head cooling started before postischemic seizures in fetal sheep Pediatrics 102 1998 1098 1106
    • (1998) Pediatrics , vol.102 , pp. 1098-1106
    • Gunn, A.1    Gunn, T.2    Gunning, M.3    Williams, C.4    Gluckman, P.5
  • 11
    • 0037477629 scopus 로고    scopus 로고
    • Activation of innate immunity in the CNS triggers neurodegeneration through a Toll-like receptor 4-dependent pathway
    • S.M.L. Lehnardt, P. Follett, F.E. Jensen, R. Ratan, P.A. Rosenberg, and J.J. Volpe Activation of innate immunity in the CNS triggers neurodegeneration through a Toll-like receptor 4-dependent pathway PNAS 100 2003 8514 8519
    • (2003) PNAS , vol.100 , pp. 8514-8519
    • Lehnardt, S.M.L.1    Follett, P.2    Jensen, F.E.3    Ratan, R.4    Rosenberg, P.A.5    Volpe, J.J.6
  • 13
    • 0032488370 scopus 로고    scopus 로고
    • Antepartum risk factors for newborn encephalopathy: The Western Australian case-control study
    • N. Badawi, J.J. Kurinczuk, J.M. Keogh, L.M. Alessandri, F. O'Sullivan, and P.R. Burton Antepartum risk factors for newborn encephalopathy: the Western Australian case-control study BMJ 317 1998 1549 1553
    • (1998) BMJ , vol.317 , pp. 1549-1553
    • Badawi, N.1    Kurinczuk, J.J.2    Keogh, J.M.3    Alessandri, L.M.4    O'Sullivan, F.5    Burton, P.R.6
  • 14
    • 4644316075 scopus 로고    scopus 로고
    • Comparison of intrapartum fetal heart rate tracings in patients with neonatal seizures vs. no seizures: What are the differences?
    • K.P. Williams, and F. Galerneau Comparison of intrapartum fetal heart rate tracings in patients with neonatal seizures vs. no seizures: what are the differences? J Perinat Med 32 2004 422 425
    • (2004) J Perinat Med , vol.32 , pp. 422-425
    • Williams, K.P.1    Galerneau, F.2
  • 15
    • 77954310485 scopus 로고    scopus 로고
    • Obstetric aspects of hypoxic ischemic encephalopathy
    • S. Kumar, and S. Paterson-Brown Obstetric aspects of hypoxic ischemic encephalopathy Early Hum Dev 86 2010 339 344
    • (2010) Early Hum Dev , vol.86 , pp. 339-344
    • Kumar, S.1    Paterson-Brown, S.2
  • 16
    • 0037342893 scopus 로고    scopus 로고
    • Intrapartum fetal heart rate patterns in the prediction of neonatal acidemia
    • K.P. Williams, and F. Galerneau Intrapartum fetal heart rate patterns in the prediction of neonatal acidemia Am J Obstet Gynaecol 188 2003 820 823
    • (2003) Am J Obstet Gynaecol , vol.188 , pp. 820-823
    • Williams, K.P.1    Galerneau, F.2
  • 17
    • 34548507757 scopus 로고    scopus 로고
    • The intrapartum deceleration in center stage: A physiologic approach to the interpretation of fetal heart rate changes in labor
    • J. Westgate, B. Wibbens, L. Bennet, G. Wassink, J. Parer, and A. Gunn The intrapartum deceleration in center stage: a physiologic approach to the interpretation of fetal heart rate changes in labor Am J Obstet Gynaecol 197 2007 236.e1 236.e11
    • (2007) Am J Obstet Gynaecol , vol.197
    • Westgate, J.1    Wibbens, B.2    Bennet, L.3    Wassink, G.4    Parer, J.5    Gunn, A.6
  • 18
    • 79959819927 scopus 로고    scopus 로고
    • Cost-effectiveness of cardiotocography plus ST analysis of the fetal electrocardiogram compared with cardiotocography only
    • S. Vijgen, M. Westerhuis, B. Opmeer, G. Visser, K. Moons, and M. Porath Cost-effectiveness of cardiotocography plus ST analysis of the fetal electrocardiogram compared with cardiotocography only Acta Obstet Gynecol Scand 90 2011 772 778
    • (2011) Acta Obstet Gynecol Scand , vol.90 , pp. 772-778
    • Vijgen, S.1    Westerhuis, M.2    Opmeer, B.3    Visser, G.4    Moons, K.5    Porath, M.6
  • 19
    • 0037381830 scopus 로고    scopus 로고
    • Tetrahydrobiopterin precursor sepiapterin provides protection against neurotoxicity of 1-methyl-4-phenylpyridinium in nigral slice cultures
    • J.T. Madsen, P. Jansen, C. Hesslinger, M. Meyer, J. Zimmer, and J.B. Gramsbergen Tetrahydrobiopterin precursor sepiapterin provides protection against neurotoxicity of 1-methyl-4-phenylpyridinium in nigral slice cultures J Neurochem 85 2003 214 223
    • (2003) J Neurochem , vol.85 , pp. 214-223
    • Madsen, J.T.1    Jansen, P.2    Hesslinger, C.3    Meyer, M.4    Zimmer, J.5    Gramsbergen, J.B.6
  • 20
    • 57049119708 scopus 로고    scopus 로고
    • Perivascular nitric oxide and superoxide in neonatal cerebral hypoxia-ischemia
    • R.H. Fabian, J. Perez-Polo, and T.A. Kent Perivascular nitric oxide and superoxide in neonatal cerebral hypoxia-ischemia Am J Physiol Heart Circ Physiol 295 2010 h1809 h1814
    • (2010) Am J Physiol Heart Circ Physiol , vol.295
    • Fabian, R.H.1    Perez-Polo, J.2    Kent, T.A.3
  • 21
    • 70350041395 scopus 로고    scopus 로고
    • Tetrahydrobiopterin in the prevention of hypertonia in hypoxic fetal brain
    • J. Vásquez-Vivar, J. Whitsett, M. Derrick, X. Ji, L. Yu, and S. Tan Tetrahydrobiopterin in the prevention of hypertonia in hypoxic fetal brain Ann Neurol 66 2009 323 331
    • (2009) Ann Neurol , vol.66 , pp. 323-331
    • Vásquez-Vivar, J.1    Whitsett, J.2    Derrick, M.3    Ji, X.4    Yu, L.5    Tan, S.6
  • 22
    • 0019964391 scopus 로고
    • Use of tetrahydropterins in the treatment of hyperphenylalaninemia due to defective synthesis of tetrahydrobiopterin: Evidence that peripherally administered tetrahydropterins enter the brain
    • S. Kaufman, G. Kapatos, R. McInnes, J. Schulman, and W. Rizzo Use of tetrahydropterins in the treatment of hyperphenylalaninemia due to defective synthesis of tetrahydrobiopterin: evidence that peripherally administered tetrahydropterins enter the brain Pediatrics 70 1982 376 380
    • (1982) Pediatrics , vol.70 , pp. 376-380
    • Kaufman, S.1    Kapatos, G.2    McInnes, R.3    Schulman, J.4    Rizzo, W.5
  • 23
    • 77954946690 scopus 로고    scopus 로고
    • Tetrahydrobiopterin as a novel therapeutic intervention for autism
    • R. Frye, L. Huffman, and G.R. Elliott Tetrahydrobiopterin as a novel therapeutic intervention for autism Neurotherapeutics 7 2010 241 249
    • (2010) Neurotherapeutics , vol.7 , pp. 241-249
    • Frye, R.1    Huffman, L.2    Elliott, G.R.3
  • 24
    • 84881046093 scopus 로고    scopus 로고
    • Maternal tetrahydrobiopterin deficiency: The course of two pregnancies and follow-up of two children in a mother with 6-pyruvoyl-tetrahydropterin synthase deficiency
    • 10.1007/s10545-009-1073-4
    • M. Giewska, G. Hnatyszyn, L. Sagan, L. Cyryłowski, C. Zekanowski, and M. Modrzejewska Maternal tetrahydrobiopterin deficiency: the course of two pregnancies and follow-up of two children in a mother with 6-pyruvoyl- tetrahydropterin synthase deficiency J Inherit Metab Dis 2009 10.1007/s10545-009-1073-4
    • (2009) J Inherit Metab Dis
    • Giewska, M.1    Hnatyszyn, G.2    Sagan, L.3    Cyryłowski, L.4    Zekanowski, C.5    Modrzejewska, M.6
  • 25
    • 84897922518 scopus 로고    scopus 로고
    • Long-term follow-up of patients with phenylketonuria receiving tetrahydrobiopterin treatment
    • 10.1007/s10545-010-9058-x
    • F.K. Trefz, D. Scheible, and G. Frauendienst-Egger Long-term follow-up of patients with phenylketonuria receiving tetrahydrobiopterin treatment J Inherit Metab Dis 2010 10.1007/s10545-010-9058-x
    • (2010) J Inherit Metab Dis
    • Trefz, F.K.1    Scheible, D.2    Frauendienst-Egger, G.3
  • 26
    • 0020469050 scopus 로고
    • Atypical phenylketonuria due to biopterin deficiency. Early treatment with tetrahydrobiopterin and neurotransmitter precursors, trials of monotherapy
    • W. Endres, A. Niederwieser, H. Curtius, M. Wang, B. Ohrt, and J. Schaub Atypical phenylketonuria due to biopterin deficiency. Early treatment with tetrahydrobiopterin and neurotransmitter precursors, trials of monotherapy Helv Paediatr Acta 37 1982 489 498
    • (1982) Helv Paediatr Acta , vol.37 , pp. 489-498
    • Endres, W.1    Niederwieser, A.2    Curtius, H.3    Wang, M.4    Ohrt, B.5    Schaub, J.6
  • 28
    • 0024419119 scopus 로고
    • Tetrahydrobiopterin administration in biopterin-deficient progressive dystonia with diurnal variation
    • J. Fink, P. Ravin, C. Argoff, R. Levine, R. Brady, and M. Hallett Tetrahydrobiopterin administration in biopterin-deficient progressive dystonia with diurnal variation Neurology 39 1989 1393 1395
    • (1989) Neurology , vol.39 , pp. 1393-1395
    • Fink, J.1    Ravin, P.2    Argoff, C.3    Levine, R.4    Brady, R.5    Hallett, M.6
  • 29
    • 0042868558 scopus 로고    scopus 로고
    • Autosomal dominant guanosine triphosphate cyclohydrolase i deficiency (Segawa disease)
    • M. Segawa, Y. Nomura, and N. Nishiyama Autosomal dominant guanosine triphosphate cyclohydrolase I deficiency (Segawa disease) Ann Neurol 54 2003 S32 S45
    • (2003) Ann Neurol , vol.54
    • Segawa, M.1    Nomura, Y.2    Nishiyama, N.3
  • 30
    • 34247151073 scopus 로고    scopus 로고
    • Melatonin: Therapeutic and clinical utilization
    • A. Altun, and B. Ugur-Altun Melatonin: therapeutic and clinical utilization Int J Clin Pract 61 2007 835 845
    • (2007) Int J Clin Pract , vol.61 , pp. 835-845
    • Altun, A.1    Ugur-Altun, B.2
  • 32
    • 27644552995 scopus 로고    scopus 로고
    • Antioxidative protection by melatonin: Multiplicity of mechanisms from radical detoxification to radical avoidance
    • R. Hardeland Antioxidative protection by melatonin: multiplicity of mechanisms from radical detoxification to radical avoidance Endocrine 27 2005 119 130
    • (2005) Endocrine , vol.27 , pp. 119-130
    • Hardeland, R.1
  • 35
    • 0018419710 scopus 로고
    • Maternal-fetal transfer of melatonin in the non-human primate
    • S. Reppert, R. Chez, A. Anderson, and D. Klein Maternal-fetal transfer of melatonin in the non-human primate Pediatr Res 13 1979 788 791
    • (1979) Pediatr Res , vol.13 , pp. 788-791
    • Reppert, S.1    Chez, R.2    Anderson, A.3    Klein, D.4
  • 36
    • 0025809709 scopus 로고
    • Lack of effect of melatonin on myometrial electromyographic activity in the pregnant sheep at 138-142 days gestation (term = 147 days gestation)
    • D. Sadowsky, S. Yellon, M. Mitchell, and P. Nathanielsz Lack of effect of melatonin on myometrial electromyographic activity in the pregnant sheep at 138-142 days gestation (term = 147 days gestation) Endocronology 128 1991 1812 1818
    • (1991) Endocronology , vol.128 , pp. 1812-1818
    • Sadowsky, D.1    Yellon, S.2    Mitchell, M.3    Nathanielsz, P.4
  • 37
    • 0023777881 scopus 로고
    • Plasma, cerebrospinal fluid, and brain distribution of 14C-melatonin in rat: A biochemical and autoradiographic study
    • P. Vitte, C. Harthe, P. Lestage, B. Claustrat, and P. Bobillier Plasma, cerebrospinal fluid, and brain distribution of 14C-melatonin in rat: a biochemical and autoradiographic study J Pineal Res 5 1988 437 453
    • (1988) J Pineal Res , vol.5 , pp. 437-453
    • Vitte, P.1    Harthe, C.2    Lestage, P.3    Claustrat, B.4    Bobillier, P.5
  • 39
    • 0036135872 scopus 로고    scopus 로고
    • Melatoninergic neuroprotection of the murine periventricular white matter against neonatal excitotoxic challenge
    • I. Husson, B. Mespls, P. Bac, J. Vamecq, P. Evrard, and P. Gressens Melatoninergic neuroprotection of the murine periventricular white matter against neonatal excitotoxic challenge Ann Neurol 51 2002 82 92
    • (2002) Ann Neurol , vol.51 , pp. 82-92
    • Husson, I.1    Mespls, B.2    Bac, P.3    Vamecq, J.4    Evrard, P.5    Gressens, P.6
  • 40
    • 0344069780 scopus 로고    scopus 로고
    • Maternal and developmental toxicity evaluation of melatonin administered orally to pregnant Sprague-Dawley rats
    • G. Jahnke, M. Marr, C. Myers, R. Wilson, G. Travlos, and C. Price Maternal and developmental toxicity evaluation of melatonin administered orally to pregnant Sprague-Dawley rats Toxicol Sci 50 1999 271 279
    • (1999) Toxicol Sci , vol.50 , pp. 271-279
    • Jahnke, G.1    Marr, M.2    Myers, C.3    Wilson, R.4    Travlos, G.5    Price, C.6
  • 41
    • 84858343110 scopus 로고    scopus 로고
    • Improved neuroprotection with melatonin-augmented hypothermia vs hypothermia alone in a perinatal asphysia model
    • N. Robertson, E. Powell, S. Faulkner, A. Bainbridge, M. Chandrasekaran, and M. Hristova Improved neuroprotection with melatonin-augmented hypothermia vs hypothermia alone in a perinatal asphysia model EPAS 2012
    • (2012) EPAS
    • Robertson, N.1    Powell, E.2    Faulkner, S.3    Bainbridge, A.4    Chandrasekaran, M.5    Hristova, M.6
  • 42
    • 33846463411 scopus 로고    scopus 로고
    • Melatonin reduces inflammation and cell death in white matter in the mid-gestation fetal sheep following umbilical cord occlusion
    • A.K. Welin, P. Svedin, R. Lapatto, B. Sultan, H. Hagberg, and P. Gressens Melatonin reduces inflammation and cell death in white matter in the mid-gestation fetal sheep following umbilical cord occlusion Pediatr Res 61 2007 153 158
    • (2007) Pediatr Res , vol.61 , pp. 153-158
    • Welin, A.K.1    Svedin, P.2    Lapatto, R.3    Sultan, B.4    Hagberg, H.5    Gressens, P.6
  • 43
    • 0030278981 scopus 로고    scopus 로고
    • Use of melatonin in the treatment of paediatric sleep disorders
    • J. Jan, and M. O'Donnell Use of melatonin in the treatment of paediatric sleep disorders J Pineal Res 21 1996 193 199
    • (1996) J Pineal Res , vol.21 , pp. 193-199
    • Jan, J.1    O'Donnell, M.2
  • 45
    • 2342535627 scopus 로고    scopus 로고
    • Melatonin as an antioxidant: Biochemical mechanisms and pathophysiological implications in humans
    • R. Reiter, D. Tan, J. Mayo, R. Sainz, J. Leon, and Z. Czarnocki Melatonin as an antioxidant: biochemical mechanisms and pathophysiological implications in humans Acta Biochim Pol 50 2003 1129 1146
    • (2003) Acta Biochim Pol , vol.50 , pp. 1129-1146
    • Reiter, R.1    Tan, D.2    Mayo, J.3    Sainz, R.4    Leon, J.5    Czarnocki, Z.6
  • 46
    • 23244440004 scopus 로고    scopus 로고
    • Melatonin provides neuroprotection in the late-gestation fetal sheep brain in response to umbilical cord occlusion
    • S.L. Miller, E.B. Yan, M. Castillo-Meléndez, G. Jenkin, and D.W. Walker Melatonin provides neuroprotection in the late-gestation fetal sheep brain in response to umbilical cord occlusion Dev Neurosci 27 2005 200 210
    • (2005) Dev Neurosci , vol.27 , pp. 200-210
    • Miller, S.L.1    Yan, E.B.2    Castillo-Meléndez, M.3    Jenkin, G.4    Walker, D.W.5
  • 47
    • 68549121055 scopus 로고    scopus 로고
    • Neuroprotective properties of melatonin in a model of birth asphyxia in the spiny mouse (Acomys cahirinus)
    • L.C. Hutton, M. Abbass, H. Dickinson, Z. Ireland, and D.W. Walker Neuroprotective properties of melatonin in a model of birth asphyxia in the spiny mouse (Acomys cahirinus) Dev Neurosci 31 2009 437 451
    • (2009) Dev Neurosci , vol.31 , pp. 437-451
    • Hutton, L.C.1    Abbass, M.2    Dickinson, H.3    Ireland, Z.4    Walker, D.W.5
  • 48
    • 0034755034 scopus 로고    scopus 로고
    • Increased levels of malondialdehyde and nitrite/nitrate in the blood of asphyxiated newborns: Reduction by melatonin
    • F. Fulia, E. Gitto, S. Cuzzocrea, R. Reiter, L. Dugo, and P. Gitto Increased levels of malondialdehyde and nitrite/nitrate in the blood of asphyxiated newborns: reduction by melatonin J Pineal Res 31 2005 343 349
    • (2005) J Pineal Res , vol.31 , pp. 343-349
    • Fulia, F.1    Gitto, E.2    Cuzzocrea, S.3    Reiter, R.4    Dugo, L.5    Gitto, P.6
  • 50
    • 77749336553 scopus 로고    scopus 로고
    • Melatonin protects periventricular white matter from damage due to hypoxia
    • C. Kaur, V. Sivakumar, and E. Ling Melatonin protects periventricular white matter from damage due to hypoxia J Pineal Res 48 2010 185 193
    • (2010) J Pineal Res , vol.48 , pp. 185-193
    • Kaur, C.1    Sivakumar, V.2    Ling, E.3
  • 52
    • 34147182756 scopus 로고    scopus 로고
    • N-acetylcysteine reduces lipopolysaccharide-sensitized hypoxic-ischemic brain injury
    • X. Wang, P. Svedin, C. Nie, R. Lapatto, C. Zhu, and M. Gustavsson N-acetylcysteine reduces lipopolysaccharide-sensitized hypoxic-ischemic brain injury Ann Neurol 61 2007 263 271
    • (2007) Ann Neurol , vol.61 , pp. 263-271
    • Wang, X.1    Svedin, P.2    Nie, C.3    Lapatto, R.4    Zhu, C.5    Gustavsson, M.6
  • 53
    • 0038233014 scopus 로고    scopus 로고
    • Nitric oxide-mediated mitochondrial damage in the brain: Mechanisms and implications for neurodegenerative diseases
    • J. Bolanos, A. Almeida, V. Stewart, S. Peuchen, J. Land, and J. Clark Nitric oxide-mediated mitochondrial damage in the brain: mechanisms and implications for neurodegenerative diseases J Neurochem 68 1997 2227 2240
    • (1997) J Neurochem , vol.68 , pp. 2227-2240
    • Bolanos, J.1    Almeida, A.2    Stewart, V.3    Peuchen, S.4    Land, J.5    Clark, J.6
  • 54
    • 1842665660 scopus 로고    scopus 로고
    • The localization of neuronal nitric oxide synthase may influence its role in neuronal precursor proliferation and synaptic maintenance
    • J. Chen, Y. Tu, C. Moon, V. Matarazzo, A. Palmer, and G. Ronnett The localization of neuronal nitric oxide synthase may influence its role in neuronal precursor proliferation and synaptic maintenance Dev Biol 269 2004 165 182
    • (2004) Dev Biol , vol.269 , pp. 165-182
    • Chen, J.1    Tu, Y.2    Moon, C.3    Matarazzo, V.4    Palmer, A.5    Ronnett, G.6
  • 55
    • 33751002345 scopus 로고    scopus 로고
    • Intervention strategies for neonatal hypoxic-ischemic cerebral injury
    • J. Perlman Intervention strategies for neonatal hypoxic-ischemic cerebral injury Clin Ther 28 2006 1353 1365
    • (2006) Clin Ther , vol.28 , pp. 1353-1365
    • Perlman, J.1
  • 56
    • 0032822818 scopus 로고    scopus 로고
    • Core and penumbral nitric oxide synthase activity during cerebral ischemia and reperfusion in the rat pup
    • S. Ashwal, B. Tone, H. Tian, D. Cole, B. Liwnicz, and W. Pearce Core and penumbral nitric oxide synthase activity during cerebral ischemia and reperfusion in the rat pup Pediatr Res 46 1999 390 400
    • (1999) Pediatr Res , vol.46 , pp. 390-400
    • Ashwal, S.1    Tone, B.2    Tian, H.3    Cole, D.4    Liwnicz, B.5    Pearce, W.6
  • 57
    • 0034040616 scopus 로고    scopus 로고
    • Nitric oxide-related brain damage in acute ischemic stroke
    • J. Castillo, R. Rama, and A. Davalos Nitric oxide-related brain damage in acute ischemic stroke Stroke 31 2000 852 857
    • (2000) Stroke , vol.31 , pp. 852-857
    • Castillo, J.1    Rama, R.2    Davalos, A.3
  • 58
    • 0041378072 scopus 로고    scopus 로고
    • Hypoxia-induced caspase-3 activation and DNA fragmentation in cortical neurons of newborn piglets: Role of nitric oxide
    • N. Parikh, C. Katsetos, Q. Ashraf, S. Haider, A. Legido, and M. Delivoria-Papadopoulos Hypoxia-induced caspase-3 activation and DNA fragmentation in cortical neurons of newborn piglets: role of nitric oxide Neurochem Res 28 2003 1351 1357
    • (2003) Neurochem Res , vol.28 , pp. 1351-1357
    • Parikh, N.1    Katsetos, C.2    Ashraf, Q.3    Haider, S.4    Legido, A.5    Delivoria- Papadopoulos, M.6
  • 59
    • 21444442708 scopus 로고    scopus 로고
    • Nitric oxide synthase inhibitors in experimental ischemic stroke and their effects on infarct size and cerebral blood flow: A systematic review
    • M. Willmot, C. Gibson, L. Gray, S. Murphy, and P. Bath Nitric oxide synthase inhibitors in experimental ischemic stroke and their effects on infarct size and cerebral blood flow: a systematic review Free Radic Biol Med 39 2005 412 425
    • (2005) Free Radic Biol Med , vol.39 , pp. 412-425
    • Willmot, M.1    Gibson, C.2    Gray, L.3    Murphy, S.4    Bath, P.5
  • 60
    • 61449263657 scopus 로고    scopus 로고
    • Discovery of highly potent and selective inhibitors of neuronal nitric oxide synthase by fragment hopping
    • H. Ji, H. Li, P. Martasek, L. Roman, T. Poulos, and R. Silverman Discovery of highly potent and selective inhibitors of neuronal nitric oxide synthase by fragment hopping J Med Chem 52 2009 779 797
    • (2009) J Med Chem , vol.52 , pp. 779-797
    • Ji, H.1    Li, H.2    Martasek, P.3    Roman, L.4    Poulos, T.5    Silverman, R.6
  • 61
    • 41149145121 scopus 로고    scopus 로고
    • Minimal pharmacophoric elements and fragment hopping, an approach directed at molecular diversity and isozyme selectivity. Design of selective neuronal nitric oxide synthase inhibitors
    • H. Ji, B. Stanton, J. Igarashi, H. Li, P. Martasek, and L. Roman Minimal pharmacophoric elements and fragment hopping, an approach directed at molecular diversity and isozyme selectivity. Design of selective neuronal nitric oxide synthase inhibitors J Am Chem Soc 130 2008 3900 3914
    • (2008) J Am Chem Soc , vol.130 , pp. 3900-3914
    • Ji, H.1    Stanton, B.2    Igarashi, J.3    Li, H.4    Martasek, P.5    Roman, L.6
  • 62
    • 62549102043 scopus 로고    scopus 로고
    • Selective neuronal nitric oxide synthase inhibitors and the prevention of cerebral palsy
    • H. Ji, S. Tan, J. Igarashi, H. Li, M. Derrick, and P. Martasek Selective neuronal nitric oxide synthase inhibitors and the prevention of cerebral palsy Ann Neurol 65 2009 209 217
    • (2009) Ann Neurol , vol.65 , pp. 209-217
    • Ji, H.1    Tan, S.2    Igarashi, J.3    Li, H.4    Derrick, M.5    Martasek, P.6
  • 63
    • 80255131292 scopus 로고    scopus 로고
    • Neuronal NOS inhibition prevents cerebral palsy following hypoxia-ischemia in fetal rabbits: Comparison between JI-8 and 7-nitroindazole
    • L. Yu, M. Derrick, H. Ji, R. Silverman, J. Whitsett, and J. Vasquez-Vivar Neuronal NOS inhibition prevents cerebral palsy following hypoxia-ischemia in fetal rabbits: Comparison between JI-8 and 7-nitroindazole Dev Neurosci 33 2011 312 319
    • (2011) Dev Neurosci , vol.33 , pp. 312-319
    • Yu, L.1    Derrick, M.2    Ji, H.3    Silverman, R.4    Whitsett, J.5    Vasquez-Vivar, J.6
  • 64
    • 0036957263 scopus 로고    scopus 로고
    • Inhibition of nNOS and iNOS following hypoxia-ischaemia improves long-term outcome but does not influence the inflammatory response in the neonatal rat brain
    • E.R. van den Tweel, C. Peeters-Scholte, F. van Bel, C.J. Heijnen, and F. Groenendaal Inhibition of nNOS and iNOS following hypoxia-ischaemia improves long-term outcome but does not influence the inflammatory response in the neonatal rat brain Dev Neurosci 24 2002 389 395
    • (2002) Dev Neurosci , vol.24 , pp. 389-395
    • Van Den Tweel, E.R.1    Peeters-Scholte, C.2    Van Bel, F.3    Heijnen, C.J.4    Groenendaal, F.5
  • 65
    • 34547484898 scopus 로고    scopus 로고
    • Nitric oxide synthase isoform inhibition before whole body ischemia reperfusion in pigs: Vital or protective?
    • J. Adams, D. Wu, J. Bassuk, J. Arias, H. Lozano, and P. Kurlansky Nitric oxide synthase isoform inhibition before whole body ischemia reperfusion in pigs: vital or protective? Resuscitation 74 2007 516 525
    • (2007) Resuscitation , vol.74 , pp. 516-525
    • Adams, J.1    Wu, D.2    Bassuk, J.3    Arias, J.4    Lozano, H.5    Kurlansky, P.6
  • 66
    • 34548324512 scopus 로고    scopus 로고
    • Gender-dependent pathways of hypoxia-ischemia-induced cell death and neuroprotection in the immature P3 rat
    • C.H. Nijboer, A. Kavelaars, F. van Bel, C.J. Heijnen, and F. Groenendaal Gender-dependent pathways of hypoxia-ischemia-induced cell death and neuroprotection in the immature P3 rat Dev Neurosci 29 2007 385 392
    • (2007) Dev Neurosci , vol.29 , pp. 385-392
    • Nijboer, C.H.1    Kavelaars, A.2    Van Bel, F.3    Heijnen, C.J.4    Groenendaal, F.5
  • 67
    • 33846441658 scopus 로고    scopus 로고
    • Gender-specific neuroprotection by 2-iminobiotin after hypoxia-ischemia in the neonatal rat via a nitric oxide independent pathway
    • C.H. Nijboer, F. Groenendaal, A. Kavelaars, H.H. Hagberg, F. van Bel, and C.J. Heijnen Gender-specific neuroprotection by 2-iminobiotin after hypoxia-ischemia in the neonatal rat via a nitric oxide independent pathway J Cereb Blood Flow Metab 27 2007 282 292
    • (2007) J Cereb Blood Flow Metab , vol.27 , pp. 282-292
    • Nijboer, C.H.1    Groenendaal, F.2    Kavelaars, A.3    Hagberg, H.H.4    Van Bel, F.5    Heijnen, C.J.6
  • 69
    • 1642457188 scopus 로고    scopus 로고
    • Two-pore-domain K+ channels are a novel target for the anesthetic gases xenon, nitrous oxide, and cyclopropane
    • M. Gruss, T.J. Bushell, D.P. Bright, W.R. Lieb, A. Mathie, and N.P. Franks Two-pore-domain K+ channels are a novel target for the anesthetic gases xenon, nitrous oxide, and cyclopropane Mol Pharmacol 65 2004 443 452
    • (2004) Mol Pharmacol , vol.65 , pp. 443-452
    • Gruss, M.1    Bushell, T.J.2    Bright, D.P.3    Lieb, W.R.4    Mathie, A.5    Franks, N.P.6
  • 70
    • 0034992405 scopus 로고    scopus 로고
    • Participation of the Ca(2+)-calmodulin-activated Kinase II in the control of metaphase-anaphase transition in human cells
    • C.P. Petzelt, S. Kodirov, G. Taschenberger, and W.J. Kox Participation of the Ca(2+)-calmodulin-activated Kinase II in the control of metaphase-anaphase transition in human cells Cell Biol Int 25 2001 403 409
    • (2001) Cell Biol Int , vol.25 , pp. 403-409
    • Petzelt, C.P.1    Kodirov, S.2    Taschenberger, G.3    Kox, W.J.4
  • 71
  • 72
    • 65249167552 scopus 로고    scopus 로고
    • Xenon preconditioning protects against renal ischemic-reperfusion injury via HIF-1alpha activation
    • D. Ma, T. Lim, J. Xu, H. Tang, Y. Wan, and H. Zhao Xenon preconditioning protects against renal ischemic-reperfusion injury via HIF-1alpha activation J Am Soc Nephrol 20 2009 713 720
    • (2009) J Am Soc Nephrol , vol.20 , pp. 713-720
    • Ma, D.1    Lim, T.2    Xu, J.3    Tang, H.4    Wan, Y.5    Zhao, H.6
  • 75
    • 67649522015 scopus 로고    scopus 로고
    • General anesthetics and the developing brain
    • G. Istaphanous, and A. Loepke General anesthetics and the developing brain Curr Opin Anaesthesiol 22 2009 368 373
    • (2009) Curr Opin Anaesthesiol , vol.22 , pp. 368-373
    • Istaphanous, G.1    Loepke, A.2
  • 76
    • 0030993036 scopus 로고    scopus 로고
    • Xenon provides faster emergence from anesthesia than does nitrous oxidesevoflurane or nitrous oxide-isoflurane
    • T. Goto, H. Saito, M. Shinkai, Y. Nakata, F. Ichinose, and S. Morita Xenon provides faster emergence from anesthesia than does nitrous oxidesevoflurane or nitrous oxide-isoflurane Anaesthesiology 86 1997 1273 1278
    • (1997) Anaesthesiology , vol.86 , pp. 1273-1278
    • Goto, T.1    Saito, H.2    Shinkai, M.3    Nakata, Y.4    Ichinose, F.5    Morita, S.6
  • 77
    • 23244461697 scopus 로고    scopus 로고
    • Xenon and hypothermia combine to provide neuroprotection from neonatal asphyxia
    • D. Ma, M. Hossain, A. Chow, M. Arshad, R. Battson, and R. Sanders Xenon and hypothermia combine to provide neuroprotection from neonatal asphyxia Ann Neurol 58 2005 182 193
    • (2005) Ann Neurol , vol.58 , pp. 182-193
    • Ma, D.1    Hossain, M.2    Chow, A.3    Arshad, M.4    Battson, R.5    Sanders, R.6
  • 78
    • 41149176603 scopus 로고    scopus 로고
    • Xenon and hypothermia combine additively, offering long-term functional and histopathologic neuroprotection after neonatal hypoxia/ischemia
    • C. Hobbs, M. Thoresen, A. Tucker, K. Aquilina, E. Chakkarapani, and J. Dingley Xenon and hypothermia combine additively, offering long-term functional and histopathologic neuroprotection after neonatal hypoxia/ischemia Stroke 39 2008 1307 1313
    • (2008) Stroke , vol.39 , pp. 1307-1313
    • Hobbs, C.1    Thoresen, M.2    Tucker, A.3    Aquilina, K.4    Chakkarapani, E.5    Dingley, J.6
  • 79
    • 13544267798 scopus 로고    scopus 로고
    • Randomized controlled trial of the haemodynamic and recovery effects of xenon or propofol anaesthesia
    • M. Coburn, O. Kunitz, J.H. Baumert, K. Hecker, S. Haaf, and A. Zühlsdorff Randomized controlled trial of the haemodynamic and recovery effects of xenon or propofol anaesthesia Br J Anaesth 94 2005 198 202
    • (2005) Br J Anaesth , vol.94 , pp. 198-202
    • Coburn, M.1    Kunitz, O.2    Baumert, J.H.3    Hecker, K.4    Haaf, S.5    Zühlsdorff, A.6
  • 80
    • 0036171884 scopus 로고    scopus 로고
    • Xenon produces minimal haemodynamic effects in rabbits with chronically compromised left ventricular function
    • B. Preckel, W. Schlack, T. Heibel, and H. Rütten Xenon produces minimal haemodynamic effects in rabbits with chronically compromised left ventricular function Br J Anaesth 88 2002 264 299
    • (2002) Br J Anaesth , vol.88 , pp. 264-299
    • Preckel, B.1    Schlack, W.2    Heibel, T.3    Rütten, H.4
  • 81
    • 0023823663 scopus 로고
    • Intravenous 133Xe clearance in preterm neonates with respiratory distress. Internal validation of CBF infinity as a measure of global cerebral blood flow
    • G. Greisen, and O. Pryds Intravenous 133Xe clearance in preterm neonates with respiratory distress. Internal validation of CBF infinity as a measure of global cerebral blood flow Scand J Clin Lab Invest 48 1988 673 678
    • (1988) Scand J Clin Lab Invest , vol.48 , pp. 673-678
    • Greisen, G.1    Pryds, O.2
  • 83
    • 0036263574 scopus 로고    scopus 로고
    • Effects of xenon on in vitro and in vivo models of neuronal injury
    • S. Wilhelm, D. Ma, M. Maze, and N. Franks Effects of xenon on in vitro and in vivo models of neuronal injury Anaesthesiology 96 2002 1485 1491
    • (2002) Anaesthesiology , vol.96 , pp. 1485-1491
    • Wilhelm, S.1    Ma, D.2    Maze, M.3    Franks, N.4
  • 84
    • 0042324880 scopus 로고    scopus 로고
    • Combination of xenon and isoflurane produces a synergistic protective effect against oxygen-glucose deprivation injury in a neuronal-glial co-culture model
    • D. Ma, M. Hossain, N. Rajakumaraswamy, N.P. Franks, and M. Maze Combination of xenon and isoflurane produces a synergistic protective effect against oxygen-glucose deprivation injury in a neuronal-glial co-culture model Anaesthesiology 99 2003 748 751
    • (2003) Anaesthesiology , vol.99 , pp. 748-751
    • Ma, D.1    Hossain, M.2    Rajakumaraswamy, N.3    Franks, N.P.4    Maze, M.5
  • 85
    • 33644848728 scopus 로고    scopus 로고
    • Xenon provides short-term neuroprotection in neonatal rats when administered after hypoxia-ischemia
    • J. Dingley, J. Tooley, H. Porter, and M. Thoresen Xenon provides short-term neuroprotection in neonatal rats when administered after hypoxia-ischemia Stroke 37 2006 501 506
    • (2006) Stroke , vol.37 , pp. 501-506
    • Dingley, J.1    Tooley, J.2    Porter, H.3    Thoresen, M.4
  • 86
    • 33847736191 scopus 로고    scopus 로고
    • Asynchronous administration of xenon and hypothermia significantly reduces brain infarction in the neonatal rat
    • J.L. Martin, D. Ma, M. Hossain, J. Xu, R.D. Sanders, N.P. Franks, and M. Maze Asynchronous administration of xenon and hypothermia significantly reduces brain infarction in the neonatal rat Br J Anaesth 98 2007 236 240
    • (2007) Br J Anaesth , vol.98 , pp. 236-240
    • Martin, J.L.1    Ma, D.2    Hossain, M.3    Xu, J.4    Sanders, R.D.5    Franks, N.P.6    Maze, M.7
  • 87
    • 63949083970 scopus 로고    scopus 로고
    • Cooling combined with immediate or delayed xenon inhalation provides equivalent long-term neuroprotection after neonatal hypoxia-ischemia
    • Thoresen M, Hobbs CE, HC, Wood T, Chakkarapani E, Dingley J. Cooling combined with immediate or delayed xenon inhalation provides equivalent long-term neuroprotection after neonatal hypoxia-ischemia. J Cereb Blood Flow Metab 2009;29:707-14.
    • (2009) J Cereb Blood Flow Metab , vol.29 , pp. 707-714
    • Thoresen, M.1    Hobbs, C.E.2    Wood, T.3    Chakkarapani, E.4    Dingley, J.5
  • 88
    • 79960834102 scopus 로고    scopus 로고
    • Xenon augmented hypothermia reduces early lactate/NAA and cell death in Perinatal Asphyxia
    • S. Faulkner, A. Bainbridge, T. Kato, M. Chandrasekaran, M. Hristova, and M. Liu Xenon augmented hypothermia reduces early lactate/NAA and cell death in Perinatal Asphyxia Ann Neurol 70 2011 133 150
    • (2011) Ann Neurol , vol.70 , pp. 133-150
    • Faulkner, S.1    Bainbridge, A.2    Kato, T.3    Chandrasekaran, M.4    Hristova, M.5    Liu, M.6
  • 90
    • 56149093066 scopus 로고    scopus 로고
    • Xenon and sevoflurane protect against brain injury in a neonatal asphyxia model
    • Y. Luo, D. Ma, E. Leong, R. Sanders, B. Yu, and M. Hossain Xenon and sevoflurane protect against brain injury in a neonatal asphyxia model Aneasthesiology 109 2008 782 789
    • (2008) Aneasthesiology , vol.109 , pp. 782-789
    • Luo, Y.1    Ma, D.2    Leong, E.3    Sanders, R.4    Yu, B.5    Hossain, M.6
  • 91
    • 62349116245 scopus 로고    scopus 로고
    • Neonatal exposure to sevoflurane induces abnormal social behaviors and deficits in fear conditioning in mice
    • M. Satomoto, Y. Satoh, K. Terui, H. Miyao, K. Takishima, and M. Ito Neonatal exposure to sevoflurane induces abnormal social behaviors and deficits in fear conditioning in mice Anesthesiology 110 2009 628 637
    • (2009) Anesthesiology , vol.110 , pp. 628-637
    • Satomoto, M.1    Satoh, Y.2    Terui, K.3    Miyao, H.4    Takishima, K.5    Ito, M.6
  • 92
    • 66249148382 scopus 로고    scopus 로고
    • The common inhalational anesthetic sevoflurane induces apoptosis and increases beta-amyloid protein levels
    • Y. Dong, G. Zhang, B. Zhang, R. Moir, W. Xia, and E. Marcantonio The common inhalational anesthetic sevoflurane induces apoptosis and increases beta-amyloid protein levels Arch Neurol 66 2009 620 631
    • (2009) Arch Neurol , vol.66 , pp. 620-631
    • Dong, Y.1    Zhang, G.2    Zhang, B.3    Moir, R.4    Xia, W.5    Marcantonio, E.6
  • 93
    • 77953027616 scopus 로고    scopus 로고
    • Anesthetic sevoflurane causes neurotoxicity differently in neonatal naïve and Alzheimer disease transgenic mice
    • Y. Lu, X. Wu, Y. Dong, Z. Xu, Y. Zhang, and Z. Xie Anesthetic sevoflurane causes neurotoxicity differently in neonatal naïve and Alzheimer disease transgenic mice Anesthesiology 112 2010 1404 1416
    • (2010) Anesthesiology , vol.112 , pp. 1404-1416
    • Lu, Y.1    Wu, X.2    Dong, Y.3    Xu, Z.4    Zhang, Y.5    Xie, Z.6
  • 95
    • 67649587151 scopus 로고    scopus 로고
    • Maternal allopurinol during fetal hypoxia lowers cord blood levels of the brain injury marker S-100B
    • H.L. Torrance, M.J. Benders, J.B. Derks, C.M. Rademaker, A.F. Bos, and P. Van Den Berg Maternal allopurinol during fetal hypoxia lowers cord blood levels of the brain injury marker S-100B Pediatrics 124 2009 350 357
    • (2009) Pediatrics , vol.124 , pp. 350-357
    • Torrance, H.L.1    Benders, M.J.2    Derks, J.B.3    Rademaker, C.M.4    Bos, A.F.5    Van Den Berg, P.6
  • 96
    • 77949461630 scopus 로고    scopus 로고
    • Antenatal allopurinol for reduction of birth asphyxia induced brain damage (ALLO-Trial); A randomized double blind placebo controlled multicenter study
    • J.J. Kaandorp, M.J. Benders, C.M. Rademaker, H.L. Torrance, M.A. Oudijk, and T.R. de Haan Antenatal allopurinol for reduction of birth asphyxia induced brain damage (ALLO-Trial); a randomized double blind placebo controlled multicenter study BMC Pregnancy Childbirth 10 2010 8
    • (2010) BMC Pregnancy Childbirth , vol.10 , pp. 8
    • Kaandorp, J.J.1    Benders, M.J.2    Rademaker, C.M.3    Torrance, H.L.4    Oudijk, M.A.5    De Haan, T.R.6
  • 97
    • 0027499214 scopus 로고
    • Allopurinol administered after inducing hypoxia-ischemia reduces brain injury in 7-day-old rats
    • C. Palmer, J. Towfighi, R.L. Roberts, and D.F. Heitjan Allopurinol administered after inducing hypoxia-ischemia reduces brain injury in 7-day-old rats Pediatr Res 33 1993 405 411
    • (1993) Pediatr Res , vol.33 , pp. 405-411
    • Palmer, C.1    Towfighi, J.2    Roberts, R.L.3    Heitjan, D.F.4
  • 98
    • 0026744079 scopus 로고
    • Allopurinol preserves cerebral energy metabolism during perinatal hypoxia-ischemia: A 31P NMR study in unanesthetized immature rats
    • G.D. Williams, C. Palmer, D.F. Heitjan, and M.B. Smith Allopurinol preserves cerebral energy metabolism during perinatal hypoxia-ischemia: a 31P NMR study in unanesthetized immature rats Neurosci Lett 144 1992 103 106
    • (1992) Neurosci Lett , vol.144 , pp. 103-106
    • Williams, G.D.1    Palmer, C.2    Heitjan, D.F.3    Smith, M.B.4
  • 99
    • 0026056771 scopus 로고
    • A randomized controlled trial of allopurinol in coronary bypass surgery
    • W.D. Johnson, K.L. Kayser, J.B. Brenowitz, and S.F. Saedi A randomized controlled trial of allopurinol in coronary bypass surgery Am Heart J 121 1991 20 24
    • (1991) Am Heart J , vol.121 , pp. 20-24
    • Johnson, W.D.1    Kayser, K.L.2    Brenowitz, J.B.3    Saedi, S.F.4
  • 100
    • 17844407898 scopus 로고    scopus 로고
    • Allopurinol neurocardiac protection trial in infants undergoing heart surgery using deep hypothermic circulatory arrest
    • R.R. Clancy, S.A. McGaurn, J.E. Goin, D.G. Hirtz, W.I. Norwood, and J.W. Gaynor Allopurinol neurocardiac protection trial in infants undergoing heart surgery using deep hypothermic circulatory arrest Pediatrics 108 2001 61 70
    • (2001) Pediatrics , vol.108 , pp. 61-70
    • Clancy, R.R.1    McGaurn, S.A.2    Goin, J.E.3    Hirtz, D.G.4    Norwood, W.I.5    Gaynor, J.W.6
  • 102
    • 44949172545 scopus 로고    scopus 로고
    • Allopurinol for preventing mortality and morbidity in newborn infants with suspected hypoxic-ischaemic encephalopathy
    • T. Chaudhari, and W. McGuire Allopurinol for preventing mortality and morbidity in newborn infants with suspected hypoxic-ischaemic encephalopathy Cochrane Database Sys Rev 2 2008 CD006817
    • (2008) Cochrane Database Sys Rev , vol.2 , pp. 006817
    • Chaudhari, T.1    McGuire, W.2
  • 104
    • 33947331502 scopus 로고    scopus 로고
    • Effect of allopurinol supplementation on nitric oxide levels in asphyxiated newborns
    • T. Gunes, M.A. Ozturk, E. Koklu, K. Kose, and I. Gunes Effect of allopurinol supplementation on nitric oxide levels in asphyxiated newborns Pediatr Neurol 36 2007 17 24
    • (2007) Pediatr Neurol , vol.36 , pp. 17-24
    • Gunes, T.1    Ozturk, M.A.2    Koklu, E.3    Kose, K.4    Gunes, I.5
  • 105
    • 0031930898 scopus 로고    scopus 로고
    • Effect of allopurinol on postasphyxial free radical formation, cerebral hemodynamics, and electrical brain activity
    • F. Van Bel, M. Shadid, R.M. Moison, C.A. Dorrepaal, J. Fontijn, and L. Monteiro Effect of allopurinol on postasphyxial free radical formation, cerebral hemodynamics, and electrical brain activity Pediatrics 101 1998 185 193
    • (1998) Pediatrics , vol.101 , pp. 185-193
    • Van Bel, F.1    Shadid, M.2    Moison, R.M.3    Dorrepaal, C.A.4    Fontijn, J.5    Monteiro, L.6
  • 106
    • 84864873554 scopus 로고    scopus 로고
    • Long-term neuroprotective effects of allopurinol after moderate perinatal asphyxia. Follow-up of two randomised controlled trials
    • In press
    • Kaandorp J, van Bel F, Veen S, Derks J, Groenendaal F, Rijken M, et al. Long-term neuroprotective effects of allopurinol after moderate perinatal asphyxia. Follow-up of two randomised controlled trials. Arch Dis Child. In press 2011.
    • (2011) Arch Dis Child
    • Kaandorp, J.1    Van Bel, F.2    Veen, S.3    Derks, J.4    Groenendaal, F.5    Rijken, M.6
  • 107
    • 0032476697 scopus 로고    scopus 로고
    • Ascorbate prevents the interaction of superoxide and nitric oxide only at very high physiological concentrations
    • T. Jackson, A. Xu, J. Vita, and J.J. Keaney Ascorbate prevents the interaction of superoxide and nitric oxide only at very high physiological concentrations Circ Res 83 1998 916 922
    • (1998) Circ Res , vol.83 , pp. 916-922
    • Jackson, T.1    Xu, A.2    Vita, J.3    Keaney, J.J.4
  • 109
    • 0035949516 scopus 로고    scopus 로고
    • Dehydroascorbic acid, a blood-brain barrier transportable form of vitamin C, mediates potent cerebroprotection in experimental stroke
    • J. Huang, D. Agus, C. Winfree, S. Kiss, W. Mack, and R. McTaggart Dehydroascorbic acid, a blood-brain barrier transportable form of vitamin C, mediates potent cerebroprotection in experimental stroke Proc Natl Acad Sci U S A 98 2001 11720 11724
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 11720-11724
    • Huang, J.1    Agus, D.2    Winfree, C.3    Kiss, S.4    MacK, W.5    McTaggart, R.6
  • 110
    • 33745249870 scopus 로고    scopus 로고
    • Effect of the mitochondrial antioxidant, Mito Vitamin E, on hypoxic-ischemic striatal injury in neonatal rats: A dose-response and stereological study
    • M. Covey, M. Murphy, C. Hobbs, R. Smith, and D. Oorschot Effect of the mitochondrial antioxidant, Mito Vitamin E, on hypoxic-ischemic striatal injury in neonatal rats: a dose-response and stereological study Exp Neurol 199 2006 513 519
    • (2006) Exp Neurol , vol.199 , pp. 513-519
    • Covey, M.1    Murphy, M.2    Hobbs, C.3    Smith, R.4    Oorschot, D.5
  • 111
    • 0032995902 scopus 로고    scopus 로고
    • Methylprednisolone and vitamin e therapy in perinatal hypoxic-ischemic brain damage in rats
    • M. Daneyemez, E. Kurt, A. Cosar, E. Yuce, and T. Ide Methylprednisolone and vitamin E therapy in perinatal hypoxic-ischemic brain damage in rats Neuroscience 92 1999 693 697
    • (1999) Neuroscience , vol.92 , pp. 693-697
    • Daneyemez, M.1    Kurt, E.2    Cosar, A.3    Yuce, E.4    Ide, T.5
  • 112
    • 67349096792 scopus 로고    scopus 로고
    • Ascorbic acid combined with ibuprofen in hypoxic ischemic encephalopathy: A randomized controlled trial
    • H. Aly, L. Abd-Rabboh, M. El-Dib, F. Nawwar, H. Hassan, and M. Aaref Ascorbic acid combined with ibuprofen in hypoxic ischemic encephalopathy: a randomized controlled trial J Perinatol 29 2009 438 443
    • (2009) J Perinatol , vol.29 , pp. 438-443
    • Aly, H.1    Abd-Rabboh, L.2    El-Dib, M.3    Nawwar, F.4    Hassan, H.5    Aaref, M.6
  • 113
    • 0024394697 scopus 로고
    • The antioxidant action of N-acetylcysteine: Its reaction with hydrogen peroxide, hydroxyl radical, superoxide, and hypochlorous acid
    • O. Aruoma, B. Halliwell, B. Hoey, and J. Butler The antioxidant action of N-acetylcysteine: its reaction with hydrogen peroxide, hydroxyl radical, superoxide, and hypochlorous acid Free Radic Biol Med 6 1989 593 597
    • (1989) Free Radic Biol Med , vol.6 , pp. 593-597
    • Aruoma, O.1    Halliwell, B.2    Hoey, B.3    Butler, J.4
  • 115
    • 27944481354 scopus 로고    scopus 로고
    • Effect of N-acetylcysteine on lipopolysaccharide-induced intra-uterine fetal death and intra-uterine growth retardation in mice
    • D. Xu, Y. Chen, H. Wang, L. Zhao, J. Wang, and W. Wei Effect of N-acetylcysteine on lipopolysaccharide-induced intra-uterine fetal death and intra-uterine growth retardation in mice Toxicol Sci 88 2005 525 533
    • (2005) Toxicol Sci , vol.88 , pp. 525-533
    • Xu, D.1    Chen, Y.2    Wang, H.3    Zhao, L.4    Wang, J.5    Wei, W.6
  • 116
    • 76549129490 scopus 로고    scopus 로고
    • The anti-inflammatory agent N-acetyl cysteine exacerbates endotoxin-induced hypoxemia and hypotension and induces polycythemia in the ovine fetus
    • M. Probyn, M. Cock, J. Duncan, M. Tolcos, N. Hale, and A. Shields The anti-inflammatory agent N-acetyl cysteine exacerbates endotoxin-induced hypoxemia and hypotension and induces polycythemia in the ovine fetus Neonatology 98 2010 118 127
    • (2010) Neonatology , vol.98 , pp. 118-127
    • Probyn, M.1    Cock, M.2    Duncan, J.3    Tolcos, M.4    Hale, N.5    Shields, A.6
  • 117
    • 47549090863 scopus 로고    scopus 로고
    • Acetylcysteine for acetaminophen poisoning
    • K. Heard Acetylcysteine for acetaminophen poisoning N Engl J Med 359 2008 285 292
    • (2008) N Engl J Med , vol.359 , pp. 285-292
    • Heard, K.1
  • 118
    • 0030842563 scopus 로고    scopus 로고
    • Placental transfer of N-acetylcysteine following human maternal acetaminophen toxicity
    • R. Horowitz, R. Dart, D. Jarvie, C. Bearer, and U. Gupta Placental transfer of N-acetylcysteine following human maternal acetaminophen toxicity J Toxicol Clin Toxicol 35 1997 447 451
    • (1997) J Toxicol Clin Toxicol , vol.35 , pp. 447-451
    • Horowitz, R.1    Dart, R.2    Jarvie, D.3    Bearer, C.4    Gupta, U.5
  • 120
    • 8444225845 scopus 로고    scopus 로고
    • N-acetylcysteine prevents endotoxin-induced degeneration of oligodendrocyte progenitors and hypomyelination in developing rat brain
    • M.K. Paintlia, A.S. Paintlia, E. Barbosa, I. Singh, and A.K. Singh N-acetylcysteine prevents endotoxin-induced degeneration of oligodendrocyte progenitors and hypomyelination in developing rat brain J Neurosci Res 78 2004 347 361
    • (2004) J Neurosci Res , vol.78 , pp. 347-361
    • Paintlia, M.K.1    Paintlia, A.S.2    Barbosa, E.3    Singh, I.4    Singh, A.K.5
  • 122
    • 45149090560 scopus 로고    scopus 로고
    • Late N-acetylcysteine treatment prevents the deficits induced in the offspring of dams exposed to an immune stress during gestation
    • F. Lanté, J. Meunier, J. Guiramand, M. De Jesus Ferreira, G. Cambonie, and R. Aimar Late N-acetylcysteine treatment prevents the deficits induced in the offspring of dams exposed to an immune stress during gestation Hippocampus 18 2008 602 609
    • (2008) Hippocampus , vol.18 , pp. 602-609
    • Lanté, F.1    Meunier, J.2    Guiramand, J.3    De Jesus Ferreira, M.4    Cambonie, G.5    Aimar, R.6
  • 123
    • 0037376423 scopus 로고    scopus 로고
    • Recombinant peroxiredoxin 5 protects against excitotoxic brain lesions in newborn mice
    • F. Plaisant, A. Clippe, D. Vander Stricht, B. Knoops, and P. Gressens Recombinant peroxiredoxin 5 protects against excitotoxic brain lesions in newborn mice Free Radic Biol Med 34 2003 862 872
    • (2003) Free Radic Biol Med , vol.34 , pp. 862-872
    • Plaisant, F.1    Clippe, A.2    Vander Stricht, D.3    Knoops, B.4    Gressens, P.5
  • 124
    • 77958172570 scopus 로고    scopus 로고
    • N-acetylcysteine improves hemodynamics and reduces oxidative stress in the brains of newborn piglets with hypoxia-reoxygenation injury
    • J. Liu, T. Lee, C. Chen, D. Bagim, and P. Cheung N-acetylcysteine improves hemodynamics and reduces oxidative stress in the brains of newborn piglets with hypoxia-reoxygenation injury J Neurotrauma 27 2010 1865 1873
    • (2010) J Neurotrauma , vol.27 , pp. 1865-1873
    • Liu, J.1    Lee, T.2    Chen, C.3    Bagim, D.4    Cheung, P.5
  • 125
    • 55749101366 scopus 로고    scopus 로고
    • Effects of postresuscitation N-acetylcysteine on cerebral free radical production and perfusion during reoxygenation of hypoxic newborn piglets
    • T. Lee, C. Tymafichuk, D. Bigam, and P. Cheung Effects of postresuscitation N-acetylcysteine on cerebral free radical production and perfusion during reoxygenation of hypoxic newborn piglets Pediatr Res 64 2008 256 261
    • (2008) Pediatr Res , vol.64 , pp. 256-261
    • Lee, T.1    Tymafichuk, C.2    Bigam, D.3    Cheung, P.4
  • 126
    • 33646688898 scopus 로고    scopus 로고
    • Combination of systemic hypothermia and N-acetylcysteine attenuates hypoxic-ischemic brain injury in neonatal rats
    • M. Jatana, I. Singh, A. Singh, and D. Jenkins Combination of systemic hypothermia and N-acetylcysteine attenuates hypoxic-ischemic brain injury in neonatal rats Pediatr Res 59 2006 684 689
    • (2006) Pediatr Res , vol.59 , pp. 684-689
    • Jatana, M.1    Singh, I.2    Singh, A.3    Jenkins, D.4
  • 127
    • 0030636320 scopus 로고    scopus 로고
    • Erythropoietin receptor is expressed in rat hippocampal and cerebral cortical neurons, and erythropoietin prevents in vitro glutamate-induced neuronal death
    • E. Morishita, S. Masuda, M. Nagao, Y. Yasuda, and R. Sasaki Erythropoietin receptor is expressed in rat hippocampal and cerebral cortical neurons, and erythropoietin prevents in vitro glutamate-induced neuronal death Neuroscience 76 1997 105 116
    • (1997) Neuroscience , vol.76 , pp. 105-116
    • Morishita, E.1    Masuda, S.2    Nagao, M.3    Yasuda, Y.4    Sasaki, R.5
  • 128
    • 0031893945 scopus 로고    scopus 로고
    • Erythropoietin and erythropoietin receptor in the developing human central nervous system
    • S. Juul, D. Anderson, Y. Li, and R. Christensen Erythropoietin and erythropoietin receptor in the developing human central nervous system Pediatr Res 43 1998 40 49
    • (1998) Pediatr Res , vol.43 , pp. 40-49
    • Juul, S.1    Anderson, D.2    Li, Y.3    Christensen, R.4
  • 129
    • 0035833541 scopus 로고    scopus 로고
    • Erythropoietin-mediated neuroprotection involves cross-talk between Jak2 and NF-kappaB signalling cascades
    • M. Digicaylioglu, and S. Lipton Erythropoietin-mediated neuroprotection involves cross-talk between Jak2 and NF-kappaB signalling cascades Nature 412 2001 641 647
    • (2001) Nature , vol.412 , pp. 641-647
    • Digicaylioglu, M.1    Lipton, S.2
  • 131
    • 46049118038 scopus 로고    scopus 로고
    • Neural progenitor cells treated with EPO induce angiogenesis through the production of VEGF
    • L. Wang, M. Chopp, S. Gregg, R. Zhang, H. Teng, and A. Jiang Neural progenitor cells treated with EPO induce angiogenesis through the production of VEGF J Cereb Blood Flow Metab 28 2008 1361 1368
    • (2008) J Cereb Blood Flow Metab , vol.28 , pp. 1361-1368
    • Wang, L.1    Chopp, M.2    Gregg, S.3    Zhang, R.4    Teng, H.5    Jiang, A.6
  • 132
    • 17444398206 scopus 로고    scopus 로고
    • Erythropoietin protects primary hippocampal neurons increasing the expression of brain-derived neurotrophic factor
    • B. Viviani, S. Bartesaghi, E. Corsini, P. Villa, P. Ghezzi, and A. Garau Erythropoietin protects primary hippocampal neurons increasing the expression of brain-derived neurotrophic factor J Neurochem 93 2005 412 421
    • (2005) J Neurochem , vol.93 , pp. 412-421
    • Viviani, B.1    Bartesaghi, S.2    Corsini, E.3    Villa, P.4    Ghezzi, P.5    Garau, A.6
  • 133
    • 0029021669 scopus 로고
    • Erythropoietin transplacental passage-review of animal studies
    • J. Widness, R. Schmidt, and S. Sawyer Erythropoietin transplacental passage-review of animal studies J Perinat Med 23 1995 61 70
    • (1995) J Perinat Med , vol.23 , pp. 61-70
    • Widness, J.1    Schmidt, R.2    Sawyer, S.3
  • 134
    • 68349103103 scopus 로고    scopus 로고
    • Erythropoietin sustains cognitive function and brain volume after neonatal stroke
    • F.F. Gonzalez, R. Abel, C.R. Almli, D. Mu, M. Wendland, and D.M. Ferriero Erythropoietin sustains cognitive function and brain volume after neonatal stroke Dev Neurosci 31 2009 403 411
    • (2009) Dev Neurosci , vol.31 , pp. 403-411
    • Gonzalez, F.F.1    Abel, R.2    Almli, C.R.3    Mu, D.4    Wendland, M.5    Ferriero, D.M.6
  • 135
    • 34147098024 scopus 로고    scopus 로고
    • A comparison of high-dose recombinant erythropoietin treatment regimens in brain-injured neonatal rats
    • B.A. Kellert, R.J. McPherson, and S.E. Juul A comparison of high-dose recombinant erythropoietin treatment regimens in brain-injured neonatal rats Pediatr Res 61 2007 451 455
    • (2007) Pediatr Res , vol.61 , pp. 451-455
    • Kellert, B.A.1    McPherson, R.J.2    Juul, S.E.3
  • 136
    • 49849096888 scopus 로고    scopus 로고
    • An approach to using recombinant erythropoietin for neuroprotection in very preterm infants
    • J. Fauchre, C. Dame, R. Vonthein, B. Koller, S. Arri, and M. Wolf An approach to using recombinant erythropoietin for neuroprotection in very preterm infants Pediatrics 122 2008 375 382
    • (2008) Pediatrics , vol.122 , pp. 375-382
    • Fauchre, J.1    Dame, C.2    Vonthein, R.3    Koller, B.4    Arri, S.5    Wolf, M.6
  • 137
    • 49849104424 scopus 로고    scopus 로고
    • A phase I/II trial of high-dose erythropoietin in extremely low birth weight infants: Pharmacokinetics and safety
    • Juul SE, McPherson, RJ, MR, Bauer LA, Ledbetter KJ, Gleason CA, Mayock DE. A phase I/II trial of high-dose erythropoietin in extremely low birth weight infants: pharmacokinetics and safety. Pediatrics 2008;122:383-91.
    • (2008) Pediatrics , vol.122 , pp. 383-391
    • Juul, S.E.1    McPherson, R.J.2    Bauer, L.A.3    Ledbetter, K.J.4    Gleason, C.A.5    Mayock, D.E.6
  • 138
    • 78049279683 scopus 로고    scopus 로고
    • Erythropoietin 2nd cerebral protection after acute injuries: A double-edged sword?
    • L. Velly, L. Pellegrini, B. Guillet, N. Bruder, and P. Pisano Erythropoietin 2nd cerebral protection after acute injuries: a double-edged sword? Pharmacol Ther 128 2010 445 459
    • (2010) Pharmacol Ther , vol.128 , pp. 445-459
    • Velly, L.1    Pellegrini, L.2    Guillet, B.3    Bruder, N.4    Pisano, P.5
  • 139
    • 19444377842 scopus 로고    scopus 로고
    • Erythropoietin prevents long-term sensorimotor deficits and brain injury following neonatal hypoxia-ischemia in rats
    • E. Spandou, Z. Papadopoulou, V. Soubasi, G. Karkavelas, C. Simeonidou, and A. Pazaiti Erythropoietin prevents long-term sensorimotor deficits and brain injury following neonatal hypoxia-ischemia in rats Brain Res 1045 2005 22 30
    • (2005) Brain Res , vol.1045 , pp. 22-30
    • Spandou, E.1    Papadopoulou, Z.2    Soubasi, V.3    Karkavelas, G.4    Simeonidou, C.5    Pazaiti, A.6
  • 140
    • 23244457142 scopus 로고    scopus 로고
    • Erythropoietin protects dopaminergic neurons and improves neurobehavioral outcomes in juvenile rats after neonatal hypoxia-ischemia
    • E. Demers, R. McPherson, and S. Juul Erythropoietin protects dopaminergic neurons and improves neurobehavioral outcomes in juvenile rats after neonatal hypoxia-ischemia Pediatr Res 58 2005 297 301
    • (2005) Pediatr Res , vol.58 , pp. 297-301
    • Demers, E.1    McPherson, R.2    Juul, S.3
  • 141
    • 0142218368 scopus 로고    scopus 로고
    • Protective effect of erythropoietin in neonatal hypoxic ischemia in mice
    • H. Matsushita, M. Johnston, M. Lange, and M. Wilson Protective effect of erythropoietin in neonatal hypoxic ischemia in mice Neuroreport 14 2003 1757 1761
    • (2003) Neuroreport , vol.14 , pp. 1757-1761
    • Matsushita, H.1    Johnston, M.2    Lange, M.3    Wilson, M.4
  • 142
    • 67749137294 scopus 로고    scopus 로고
    • Erythropoietin improved neurologic outcomes in newborns with hypoxic-ischemic encephalopathy
    • C. Zhu, W. Kang, F. Xu, X. Cheng, Z. Zhang, and L. Jia Erythropoietin improved neurologic outcomes in newborns with hypoxic-ischemic encephalopathy Pediatrics 124 2009 e218 e226
    • (2009) Pediatrics , vol.124
    • Zhu, C.1    Kang, W.2    Xu, F.3    Cheng, X.4    Zhang, Z.5    Jia, L.6
  • 144
    • 77953605982 scopus 로고    scopus 로고
    • Importance of erythropoietin in brain protection after cardiac surgery: A pilot study
    • N. Lakic, K. Surlan, A. Jerin, B. Meglic, N. Curk, and M. Bunc Importance of erythropoietin in brain protection after cardiac surgery: a pilot study Heart Surg Forum 13 2010 e185 e189
    • (2010) Heart Surg Forum , vol.13
    • Lakic, N.1    Surlan, K.2    Jerin, A.3    Meglic, B.4    Curk, N.5    Bunc, M.6
  • 145
    • 33750487504 scopus 로고    scopus 로고
    • Nonhematopoietic erythropoietin derivatives prevent motoneuron degeneration in vitro and in vivo
    • T. Mennini, M. De Paola, P. Bigini, C. Mastrotto, E. Fumagalli, and S. Barbera Nonhematopoietic erythropoietin derivatives prevent motoneuron degeneration in vitro and in vivo Mol Med 12 2006 153 160
    • (2006) Mol Med , vol.12 , pp. 153-160
    • Mennini, T.1    De Paola, M.2    Bigini, P.3    Mastrotto, C.4    Fumagalli, E.5    Barbera, S.6
  • 146
    • 57749116047 scopus 로고    scopus 로고
    • Therapeutic potential of erythropoietin and its structural or functional variants in the nervous system
    • A.L. Sirén, T. Fasshauer, C. Bartels, and H. Ehrenreich Therapeutic potential of erythropoietin and its structural or functional variants in the nervous system Neurotherapeutics 6 2009 108 127
    • (2009) Neurotherapeutics , vol.6 , pp. 108-127
    • Sirén, A.L.1    Fasshauer, T.2    Bartels, C.3    Ehrenreich, H.4
  • 148
    • 43749105165 scopus 로고    scopus 로고
    • High-dose erythropoietin alters platelet reactivity and bleeding time in rodents in contrast to the neuroprotective variant carbamyl-erythropoietin (CEPO)
    • A. Kirkeby, L. Torup, L. Bochsen, M. Kjalke, K. Abel, and K. Theilgaard-Monch High-dose erythropoietin alters platelet reactivity and bleeding time in rodents in contrast to the neuroprotective variant carbamyl-erythropoietin (CEPO) Thromb Haemost 99 2008 720 728
    • (2008) Thromb Haemost , vol.99 , pp. 720-728
    • Kirkeby, A.1    Torup, L.2    Bochsen, L.3    Kjalke, M.4    Abel, K.5    Theilgaard-Monch, K.6
  • 149
    • 36148988387 scopus 로고    scopus 로고
    • The Sonic hedgehog pathway mediates carbamylated erythropoietin-enhanced proliferation and differentiation of adult neural progenitor cells
    • L. Wang, Z.G. Zhang, S.R. Gregg, R.L. Zhang, Z. Jiao, and Y. LeTourneau The Sonic hedgehog pathway mediates carbamylated erythropoietin-enhanced proliferation and differentiation of adult neural progenitor cells J Biol Chem 282 2007 32462 32470
    • (2007) J Biol Chem , vol.282 , pp. 32462-32470
    • Wang, L.1    Zhang, Z.G.2    Gregg, S.R.3    Zhang, R.L.4    Jiao, Z.5    Letourneau, Y.6
  • 150
    • 77957097611 scopus 로고    scopus 로고
    • Neuroprotective properties of a novel, non-haematopoietic agonist of the erythropoietin receptor
    • S. Pankratova, D. Kiryushko, K. Sonn, V. Soroka, L.B. Køhler, and M. Rathje Neuroprotective properties of a novel, non-haematopoietic agonist of the erythropoietin receptor Brain 133 2010 2281 2294
    • (2010) Brain , vol.133 , pp. 2281-2294
    • Pankratova, S.1    Kiryushko, D.2    Sonn, K.3    Soroka, V.4    Køhler, L.B.5    Rathje, M.6
  • 151
    • 66649083892 scopus 로고    scopus 로고
    • Antenatal magnesium sulfate and neurologic outcome in preterm infants: A systematic review
    • L. Doyle, C. Crowther, P. Middleton, and S. Marret Antenatal magnesium sulfate and neurologic outcome in preterm infants: a systematic review Obstet Gynecol 113 2009 1327 1333
    • (2009) Obstet Gynecol , vol.113 , pp. 1327-1333
    • Doyle, L.1    Crowther, C.2    Middleton, P.3    Marret, S.4
  • 152
    • 0030638156 scopus 로고    scopus 로고
    • Magnesium sulfate therapy during asphyxia in near-term fetal lambs does not compromise the fetus but does not reduce cerebral injury
    • H. de Haan, A.J. Gunn, C.E. Williams, M.A. Heymann, and P.D. Gluckman Magnesium sulfate therapy during asphyxia in near-term fetal lambs does not compromise the fetus but does not reduce cerebral injury Am J Obstet Gynaecol 176 2009 18 27
    • (2009) Am J Obstet Gynaecol , vol.176 , pp. 18-27
    • De Haan, H.1    Gunn, A.J.2    Williams, C.E.3    Heymann, M.A.4    Gluckman, P.D.5
  • 153
    • 0031019040 scopus 로고    scopus 로고
    • Magnesium sulfate after transient hypoxia-ischemia fails to prevent delayed cerebral energy failure in the newborn piglet
    • J. Penrice, P. Amess, and S. Punwani Magnesium sulfate after transient hypoxia-ischemia fails to prevent delayed cerebral energy failure in the newborn piglet Pediatr Res 41 1997 443 447
    • (1997) Pediatr Res , vol.41 , pp. 443-447
    • Penrice, J.1    Amess, P.2    Punwani, S.3
  • 155
    • 0034722808 scopus 로고    scopus 로고
    • An overview of stroke therapy
    • M. Fisher, and W. Schaebitz An overview of stroke therapy Arch Intern Med 160 2000 3196 3206
    • (2000) Arch Intern Med , vol.160 , pp. 3196-3206
    • Fisher, M.1    Schaebitz, W.2
  • 156
    • 77950908035 scopus 로고    scopus 로고
    • "Control" laboratory rodents are metabolically morbid: Why it matters
    • B. Martin, S. Ji, S. Maudsley, and M. Mattson "Control" laboratory rodents are metabolically morbid: why it matters Proc Natl Acad Sci 107 2010 6127 6133
    • (2010) Proc Natl Acad Sci , vol.107 , pp. 6127-6133
    • Martin, B.1    Ji, S.2    Maudsley, S.3    Mattson, M.4
  • 157
    • 0344065373 scopus 로고    scopus 로고
    • Recommendations for standards regarding preclinical neuroprotective and restorative drug development
    • Stroke therapy academic industry roundtable (Fisher M, chair)
    • Stroke therapy academic industry roundtable (Fisher M, chair) Recommendations for standards regarding preclinical neuroprotective and restorative drug development Stroke 30 1999 2752 2758
    • (1999) Stroke , vol.30 , pp. 2752-2758
  • 158
    • 66849097996 scopus 로고    scopus 로고
    • Update of the stroke therapy academic industry roundtable preclinical recommendations
    • M. Fisher, G. Feuerstein, D. Howells, P. Hurn, T. Kent, and S. Savitz Update of the stroke therapy academic industry roundtable preclinical recommendations Stroke 40 2009 2244 2250
    • (2009) Stroke , vol.40 , pp. 2244-2250
    • Fisher, M.1    Feuerstein, G.2    Howells, D.3    Hurn, P.4    Kent, T.5    Savitz, S.6


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