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Volumn 27, Issue 10, 2010, Pages 1865-1873

N-acetylcysteine improves hemodynamics and reduces oxidative stress in the brains of newborn piglets with hypoxia-reoxygenation injury

Author keywords

carotid blood flow; hypoxia; N acetylcysteine; newborn; piglet

Indexed keywords

ACETYLCYSTEINE; ANESTHETIC AGENT; CASPASE 3; GLUTATHIONE; LACTIC ACID; LIPOXYGENASE; SEDATIVE AGENT;

EID: 77958172570     PISSN: 08977151     EISSN: None     Source Type: Journal    
DOI: 10.1089/neu.2010.1325     Document Type: Article
Times cited : (23)

References (40)
  • 1
    • 34748887764 scopus 로고    scopus 로고
    • Neuroprotective effects of propofol in acute cerebral injury
    • Adembri, C., Venturi, L., and Pellegrini-Giampietro, D. E. (2007). Neuroprotective effects of propofol in acute cerebral injury. CNS Drug Rev. 13, 333-351.
    • (2007) CNS Drug Rev. , vol.13 , pp. 333-351
    • Adembri, C.1    Venturi, L.2    Pellegrini-Giampietro, D.E.3
  • 2
    • 0035036258 scopus 로고    scopus 로고
    • Therapeutic potential of N-acetylcysteine in age-related mitochondrial neurodegenerative diseases
    • Banaclocha, M. M. (2001). Therapeutic potential of N-acetylcysteine in age-related mitochondrial neurodegenerative diseases. Med. Hypo. 56, 472-477.
    • (2001) Med. Hypo , vol.56 , pp. 472-477
    • Banaclocha, M.M.1
  • 3
    • 5444245109 scopus 로고    scopus 로고
    • Peroxynitrite inhibits relaxation and induces pulmonary artery muscle contraction in the newborn rat
    • Belik, J., Jankov, R. P., Pan, J., and Tanswell, A. K. (2004). Peroxynitrite inhibits relaxation and induces pulmonary artery muscle contraction in the newborn rat. Free Radical Biol. Med. 37, 384-392.
    • (2004) Free Radical Biol. Med. , vol.37 , pp. 384-392
    • Belik, J.1    Jankov, R.P.2    Pan, J.3    Tanswell, A.K.4
  • 4
    • 74449093727 scopus 로고    scopus 로고
    • Seizures are associated with brain injury severity in a neonatal model of hypoxia-ischemia
    • Björkman, S. T., Miller, S. M., Rose, S. E., Burke, C., and Colditz, P. B. (2010). Seizures are associated with brain injury severity in a neonatal model of hypoxia-ischemia. Neuroscience 166, 157-167.
    • (2010) Neuroscience , vol.166 , pp. 157-167
    • Björkman, S.T.1    Miller, S.M.2    Rose, S.E.3    Burke, C.4    Colditz, P.B.5
  • 6
    • 33646506832 scopus 로고    scopus 로고
    • Effect of N-acetylcysteine on blood and tissue lipid peroxidation in lipopolysaccharideinduced obstructive jaundice
    • Caglikulekci, M., Dirlik, M., Pata, C., Plasse, M., Tamer, L., Ogetman, Z., and Ercan, B. (2006). Effect of N-acetylcysteine on blood and tissue lipid peroxidation in lipopolysaccharideinduced obstructive jaundice. J. Invest. Surg. 19, 175-184.
    • (2006) J. Invest. Surg. , vol.19 , pp. 175-184
    • Caglikulekci, M.1    Dirlik, M.2    Pata, C.3    Plasse, M.4    Tamer, L.5    Ogetman, Z.6    Ercan, B.7
  • 9
    • 0035219323 scopus 로고    scopus 로고
    • The pathophysiology, diagnosis, and management of acute hepatic encephalopathy
    • Colquhoun, S. D., Lipkin, C., and Connelly, C. A. (2001). The pathophysiology, diagnosis, and management of acute hepatic encephalopathy. Adv. Intern. Med. 46, 155-176.
    • (2001) Adv. Intern. Med. , vol.46 , pp. 155-176
    • Colquhoun, S.D.1    Lipkin, C.2    Connelly, C.A.3
  • 11
    • 0031750386 scopus 로고    scopus 로고
    • Oxidative stress and altered endothelial cell function in preeclampsia
    • Davidge, S. T. (1998). Oxidative stress and altered endothelial cell function in preeclampsia. Semin Reprod Endocrinol. 16, 65-73.
    • (1998) Semin. Reprod. Endocrinol. , vol.16 , pp. 65-73
    • Davidge, S.T.1
  • 12
    • 0037195723 scopus 로고    scopus 로고
    • Regulation of brain's vascular responses to oxygen
    • Demchenko, I. T., Oury, T. D., Crapo, J. D., and Piantadosi, C. A. (2002). Regulation of brain's vascular responses to oxygen. Circ. Res. 91, 1031-1037.
    • (2002) Circ. Res. , vol.91 , pp. 1031-1037
    • Demchenko, I.T.1    Oury, T.D.2    Crapo, J.D.3    Piantadosi, C.A.4
  • 13
    • 0028916027 scopus 로고
    • N-acetylcysteine (D-and L-stereoisomers) prevents apoptotic death of neuronal cells
    • Ferrari, G., Yan, C. Y., and Greene, L. A. (1995). N-acetylcysteine (D-and L-stereoisomers) prevents apoptotic death of neuronal cells. J. Neurosci. 15, 2857-2866.
    • (1995) J. Neurosci. , vol.15 , pp. 2857-2866
    • Ferrari, G.1    Yan, C.Y.2    Greene, L.A.3
  • 14
    • 0030067559 scopus 로고    scopus 로고
    • Carotid arterial blood flow in the bovine fetus as a continuous measure of cerebral blood flow
    • Gratton, R., Carmichael, L., Homan, J., and Richardson, B. (1996). Carotid arterial blood flow in the bovine fetus as a continuous measure of cerebral blood flow. J. Soc. Gynecol. Invest. 3, 60-65.
    • (1996) J. Soc. Gynecol. Invest. , vol.3 , pp. 60-65
    • Gratton, R.1    Carmichael, L.2    Homan, J.3    Richardson, B.4
  • 16
  • 17
    • 14644437067 scopus 로고    scopus 로고
    • Doxycycline reduced cleaved caspase-3 and microglial activation in an animal model of neonatal hypoxia-ischemia
    • Jantzie, L. L., Cheung, P. Y., and Todd, K. G. (2005). Doxycycline reduced cleaved caspase-3 and microglial activation in an animal model of neonatal hypoxia-ischemia. J. Cereb. Blood Flow Metab. 25, 314-324.
    • (2005) J. Cereb. Blood Flow Metab. , vol.25 , pp. 314-324
    • Jantzie, L.L.1    Cheung, P.Y.2    Todd, K.G.3
  • 18
    • 33646688898 scopus 로고    scopus 로고
    • Combination of systemic hypothermia and N-acetylcysteine attenuates hypoxic-ischemic brain injury in neonatal rats
    • Jatana, M., Singh, I., Singh, A. K., and Jenkins, D. (2006). Combination of systemic hypothermia and N-acetylcysteine attenuates hypoxic-ischemic brain injury in neonatal rats. Pediatr. Res. 59, 684-689.
    • (2006) Pediatr. Res. , vol.59 , pp. 684-689
    • Jatana, M.1    Singh, I.2    Singh, A.K.3    Jenkins, D.4
  • 19
    • 34548691604 scopus 로고    scopus 로고
    • N-acetylcysteine improves the hemodynamics and oxidative stress in hypoxic newborn pigs reoxygenated with 100% oxygen
    • Johnson, S. T., Bigam, D. L., Emara, M., Obaid, L., Slack, G., Korbutt, G., Jewell, L. D., Van Aerde, J., and Cheung, P. Y. (2007). N-acetylcysteine improves the hemodynamics and oxidative stress in hypoxic newborn pigs reoxygenated with 100% oxygen. Shock 28, 484-490.
    • (2007) Shock , vol.28 , pp. 484-490
    • Johnson, S.T.1    Bigam, D.L.2    Emara, M.3    Obaid, L.4    Slack, G.5    Korbutt, G.6    Jewell, L.D.7    Van Aerde, J.8    Cheung, P.Y.9
  • 20
    • 2342562573 scopus 로고    scopus 로고
    • Administration of N-acetylcysteine after focal cerebral ischemia protects brain and reduces inflammation in rat model of experimental stroke
    • Khan, M., Sekhon, B., Jatana, M., Giri, S., Gilg, A. G., Sekhon, C., Singh, I., and Singh, A. K. (2004). Administration of N-acetylcysteine after focal cerebral ischemia protects brain and reduces inflammation in rat model of experimental stroke. J. Neurosci. Res. 76, 519-527.
    • (2004) J. Neurosci. Res. , vol.76 , pp. 519-527
    • Khan, M.1    Sekhon, B.2    Jatana, M.3    Giri, S.4    Gilg, A.G.5    Sekhon, C.6    Singh, I.7    Singh, A.K.8
  • 21
    • 33845499287 scopus 로고    scopus 로고
    • Caspases and their many biological functions
    • Kumar, S. (2007). Caspases and their many biological functions. Cell Death Differ. 14, 1-2.
    • (2007) Cell. Death Differ , vol.14 , pp. 1-2
    • Kumar, S.1
  • 23
    • 0034112915 scopus 로고    scopus 로고
    • Cerebral perfusion, cardiac output, and arterial pressure in patients with fulminant hepatic failure
    • Larsen, F. S., Strauss, G., Knudsen, G. M., Herzog, T. M., Hansen, B. A., and Secher, N. H. (2000). Cerebral perfusion, cardiac output, and arterial pressure in patients with fulminant hepatic failure. Crit. Care Med. 28, 996-1000.
    • (2000) Crit. Care Med. , vol.28 , pp. 996-1000
    • Larsen, F.S.1    Strauss, G.2    Knudsen, G.M.3    Herzog, T.M.4    Hansen, B.A.5    Secher, N.H.6
  • 24
    • 38149038522 scopus 로고    scopus 로고
    • Postresuscitation N-acetylcysteine treatment reduces cerebral hydrogen peroxide in the hypoxic piglet brain
    • Lee, T. F., Jantzie, L. L., Todd, K. G., and Cheung, P. Y. (2008a). Postresuscitation N-acetylcysteine treatment reduces cerebral hydrogen peroxide in the hypoxic piglet brain. Intensive Care Med. 34, 190-197.
    • (2008) Intensive Care Med. , vol.34 , pp. 190-197
    • Lee, T.F.1    Jantzie, L.L.2    Todd, K.G.3    Cheung, P.Y.4
  • 25
    • 55749101366 scopus 로고    scopus 로고
    • Effects of postresuscitation N-acetylcysteine on cerebral free radical production and perfusion during reoxygenation of hypoxic newborn piglets
    • Lee, T. F., Tymafichuk, C. N., Bigam, D. L., and Cheung, P. Y. (2008b). Effects of postresuscitation N-acetylcysteine on cerebral free radical production and perfusion during reoxygenation of hypoxic newborn piglets. Pediatr. Res. 64, 256-261.
    • (2008) Pediatr. Res. , vol.64 , pp. 256-261
    • Lee, T.F.1    Tymafichuk, C.N.2    Bigam, D.L.3    Cheung, P.Y.4
  • 26
    • 54349116734 scopus 로고    scopus 로고
    • Cerebral function monitoring in neonates with perinatal asphyxia-preliminary results
    • Lukaskova, J., Tomsikova, Z., and Kokstein, Z. (2008). Cerebral function monitoring in neonates with perinatal asphyxia-preliminary results. Neuroendocrinol. Lett. 29, 522-528.
    • (2008) Neuroendocrinol. Lett. , vol.29 , pp. 522-528
    • Lukaskova, J.1    Tomsikova, Z.2    Kokstein, Z.3
  • 27
    • 0032922184 scopus 로고    scopus 로고
    • Correlation of flow probe determinations of common carotid artery blood flow and internal carotid artery blood flow with microsphere determinations of cerebral blood flow in piglets
    • Meadow, W., Rudinsky, B., Raju, T., John, E., Fornell, L., and Shankararao, R. (1999). Correlation of flow probe determinations of common carotid artery blood flow and internal carotid artery blood flow with microsphere determinations of cerebral blood flow in piglets. Pediatr. Res. 45, 324-330.
    • (1999) Pediatr. Res. , vol.45 , pp. 324-330
    • Meadow, W.1    Rudinsky, B.2    Raju, T.3    John, E.4    Fornell, L.5    Shankararao, R.6
  • 29
    • 0033119001 scopus 로고    scopus 로고
    • Changes in iron histochemistry after hypoxicischemic brain injury in neonatal rat
    • Palmer, C., Menzies, S. L., Roberts, R. L., Pavlick, G., and Connor, J. R. (1999). Changes in iron histochemistry after hypoxicischemic brain injury in neonatal rat. J. Neurosci. Res. 56, 60-71.
    • (1999) J. Neurosci. Res. , vol.56 , pp. 60-71
    • Palmer, C.1    Menzies, S.L.2    Roberts, R.L.3    Pavlick, G.4    Connor, J.R.5
  • 30
    • 18044375993 scopus 로고    scopus 로고
    • Apoptosis and necrosis in developing cerebellum and brainstem induced after focal cerebral hypoxic-ischemic injury
    • Peng, J. H., Feng, Y., Le Blanc, M. H., Rhodes, P. G., and Parker, J. C. Jr. (2005). Apoptosis and necrosis in developing cerebellum and brainstem induced after focal cerebral hypoxic-ischemic injury. Brain Res. Dev. Brain Res. 156, 87-92.
    • (2005) Brain Res. Dev. Brain Res. , vol.156 , pp. 87-92
    • Peng, J.H.1    Feng, Y.2    Le Blanc, M.H.3    Rhodes, P.G.4    Parker Jr., J.C.5
  • 31
    • 33751002345 scopus 로고    scopus 로고
    • Intervention strategies for neonatal hypoxic-ischemic cerebral injury
    • Perlman, J. M. (2006). Intervention strategies for neonatal hypoxic-ischemic cerebral injury. Clin. Ther. 28, 1353-1365.
    • (2006) Clin. Ther. , vol.28 , pp. 1353-1365
    • Perlman, J.M.1
  • 33
    • 0036222155 scopus 로고    scopus 로고
    • Cerebral resuscitation potentials for cardiac arrest
    • Safar, P., Behringer, W., Böttiger, B. W., and Sterz, F. (2002). Cerebral resuscitation potentials for cardiac arrest. Crit. Care Med. 30 (Suppl.), S140-S144.
    • (2002) Crit. Care Med. , vol.30 , Issue.SUPPL.
    • Safar, P.1    Behringer, W.2    Böttiger, B.W.3    Sterz, F.4
  • 34
    • 0037414415 scopus 로고    scopus 로고
    • N-acetylcysteine protects against injury in a rat model of focal cerebral ischemia
    • Sekhon, B., Sekhon, C., Khan, M., Patel, S. J., Singh, I., and Singh, A. K. (2003). N-acetylcysteine protects against injury in a rat model of focal cerebral ischemia. Brain Res. 971, 1-8.
    • (2003) Brain Res. , vol.971 , pp. 1-8
    • Sekhon, B.1    Sekhon, C.2    Khan, M.3    Patel, S.J.4    Singh, I.5    Singh, A.K.6
  • 38
    • 0028291629 scopus 로고
    • Cerebral blood flow and metabolism in fulminant liver failure
    • Wendon, J. A., Harrison, P. M., Keays, R., and Williams, R. (1994). Cerebral blood flow and metabolism in fulminant liver failure. Hepatology 19, 1407-1413.
    • (1994) Hepatology , vol.19 , pp. 1407-1413
    • Wendon, J.A.1    Harrison, P.M.2    Keays, R.3    Williams, R.4
  • 39
    • 0034775517 scopus 로고    scopus 로고
    • N-acetylcysteine increases cerebral perfusion pressure in pigs with fulminant hepatic failure
    • Ytrebø, L. M., Korvald, C., Nedredal, G. I., Elvenes, O. P., Nielsen Grymyr, O. J., and Revhaug, A. (2001). N-acetylcysteine increases cerebral perfusion pressure in pigs with fulminant hepatic failure. Crit. Care Med. 29, 1989-1995.
    • (2001) Crit. Care Med. , vol.29 , pp. 1989-1995
    • Ytrebø, L.M.1    Korvald, C.2    Nedredal, G.I.3    Elvenes, O.P.4    Grymyr, N.O.J.5    Revhaug, A.6


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