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Volumn 28, Issue 9, 2003, Pages 1351-1357

Hypoxia-Induced Caspase-3 Activation and DNA Fragmentation in Cortical Neurons of Newborn Piglets: Role of Nitric Oxide

Author keywords

Caspase 3; Hypoxia; Immunoreactivity; Labeling index; Neuronal nitric oxide synthase

Indexed keywords

7 NITROINDAZOLE; ANTISERUM; CASPASE 3; DNA FRAGMENT; NEURONAL NITRIC OXIDE SYNTHASE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; ADENOSINE TRIPHOSPHATE; CASPASE; CREATINE PHOSPHATE;

EID: 0041378072     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1024992214886     Document Type: Article
Times cited : (31)

References (39)
  • 1
    • 0034519396 scopus 로고    scopus 로고
    • Hypoxia-induced generation of nitric oxide free radicals in cerebral cortex of newborn guinea pigs
    • Mishra, O. P., Zanelli, S. A., and Ohnishi, S. T. 2000. Hypoxia-induced generation of nitric oxide free radicals in cerebral cortex of newborn guinea pigs. Neurochem. Res. 25:1559-1565.
    • (2000) Neurochem. Res. , vol.25 , pp. 1559-1565
    • Mishra, O.P.1    Zanelli, S.A.2    Ohnishi, S.T.3
  • 2
    • 0028102427 scopus 로고
    • Nitrosyl hemoglobin production during reperfusion after focal cerebral-ischemia in rats
    • Kumura, E., Yshimine, T., Tanake, S., Hayakawa, T., Shiga, T., and Kosake, H. 1994. Nitrosyl hemoglobin production during reperfusion after focal cerebral-ischemia in rats. Neurosci. Lett. 177:165-167.
    • (1994) Neurosci. Lett. , vol.177 , pp. 165-167
    • Kumura, E.1    Yshimine, T.2    Tanake, S.3    Hayakawa, T.4    Shiga, T.5    Kosake, H.6
  • 3
    • 0028875770 scopus 로고
    • 3-Dimensional imaging of nitric-oxide production in the rat brain subjected to ischemia-hypoxia
    • Kuppusamy, P., Ohnishi, S. T., Numagami, Y., Ohnishi, T., and Zweiger, J. L. 1995. 3-Dimensional imaging of nitric-oxide production in the rat brain subjected to ischemia-hypoxia. J. Cereb. Blood Flow Metab. 15:899-903.
    • (1995) J. Cereb. Blood Flow Metab. , vol.15 , pp. 899-903
    • Kuppusamy, P.1    Ohnishi, S.T.2    Numagami, Y.3    Ohnishi, T.4    Zweiger, J.L.5
  • 5
    • 0027236232 scopus 로고
    • Mechanisms involved in the neuroprotective activity of a nitric oxide synthase inhibitor during focal cerebral ischemia
    • Buisson, A., Margaill, I., Callebert, M., Plotkine, M., and Boulu, R. G. 1993. Mechanisms involved in the neuroprotective activity of a nitric oxide synthase inhibitor during focal cerebral ischemia. J. Neurochem. 61:690-696.
    • (1993) J. Neurochem. , vol.61 , pp. 690-696
    • Buisson, A.1    Margaill, I.2    Callebert, M.3    Plotkine, M.4    Boulu, R.G.5
  • 6
    • 0029927787 scopus 로고    scopus 로고
    • Resistance to neurotoxicity in cortical cultures from neuronal nitric oxide synthase-deficient mice
    • Dawson, V. L., Kizushi, V. M., Huang, P. L., Snyder, S. H., and Dawson, T. M. 1996. Resistance to neurotoxicity in cortical cultures from neuronal nitric oxide synthase-deficient mice. J. Neurosci. 16:2479-2487.
    • (1996) J. Neurosci. , vol.16 , pp. 2479-2487
    • Dawson, V.L.1    Kizushi, V.M.2    Huang, P.L.3    Snyder, S.H.4    Dawson, T.M.5
  • 7
    • 0029780767 scopus 로고    scopus 로고
    • Enlarged infracts in endothelial nitric oxide synthase knockout mice are attenuated by nitro-L-arginine
    • Huang, Z., Huang P. L., Meng, W., Ayata, C., Fishman, M. C., and Moskowitz, M. A. 1996. Enlarged infracts in endothelial nitric oxide synthase knockout mice are attenuated by nitro-L-arginine. J Cereb. Blood Flow Metab. 16:981-987.
    • (1996) J. Cereb. Blood Flow Metab. , vol.16 , pp. 981-987
    • Huang, Z.1    Huang, P.L.2    Meng, W.3    Ayata, C.4    Fishman, M.C.5    Moskowitz, M.A.6
  • 8
    • 0031020172 scopus 로고    scopus 로고
    • Bright and dark sides of nitric oxide in ischemic brain injury
    • Iadecola, C. 1997. Bright and dark sides of nitric oxide in ischemic brain injury. Trends Neurosci. 20:132-139.
    • (1997) Trends Neurosci. , vol.20 , pp. 132-139
    • Iadecola, C.1
  • 9
    • 0027178135 scopus 로고
    • Mechanisms of nitric oxide-mediated neurotoxicity in primary brain cultures
    • Dawson, V. L., Dawson, T. M., Bartley, D. A., Uhl, G. R., and Snyder, S. H. 1993. Mechanisms of nitric oxide-mediated neurotoxicity in primary brain cultures. J. Neurosci. 13:2651-2661.
    • (1993) J. Neurosci. , vol.13 , pp. 2651-2661
    • Dawson, V.L.1    Dawson, T.M.2    Bartley, D.A.3    Uhl, G.R.4    Snyder, S.H.5
  • 11
    • 0030931876 scopus 로고    scopus 로고
    • Caspases: The executioners of apoptosis
    • Cohen, G. 1997. Caspases: The executioners of apoptosis. Biochem. J. 326:1-16.
    • (1997) Biochem. J. , vol.326 , pp. 1-16
    • Cohen, G.1
  • 12
    • 0036019165 scopus 로고    scopus 로고
    • Mechanisms of cell death in neurodegenerative diseases: Fashion, fiction, and facts
    • Graeber, M. B. and Moran, L. B. 2002. Mechanisms of cell death in neurodegenerative diseases: Fashion, fiction, and facts. Brain Pathol. 12:385-390.
    • (2002) Brain Pathol. , vol.12 , pp. 385-390
    • Graeber, M.B.1    Moran, L.B.2
  • 13
    • 0029956641 scopus 로고    scopus 로고
    • Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice
    • Kuida, K., Zheng, T. S., Na, S., Kuan, C., Yang, D., Karasuyama, H., Rakic, P., and Flavell, R. A. 1996. Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice. Nature 384:368-372.
    • (1996) Nature , vol.384 , pp. 368-372
    • Kuida, K.1    Zheng, T.S.2    Na, S.3    Kuan, C.4    Yang, D.5    Karasuyama, H.6    Rakic, P.7    Flavell, R.A.8
  • 14
    • 0035086441 scopus 로고    scopus 로고
    • Effect of graded hypoxia on cerebral cortical genomic DNA fragmentation in newborn piglets
    • Akhter, W., Ashraf, Q. M., Zanelli, S. A., Mishra, O. P., and Delivoria-Papadopoulos, M. 2001. Effect of graded hypoxia on cerebral cortical genomic DNA fragmentation in newborn piglets. Biol. Neonate. 79:187-193.
    • (2001) Biol. Neonate. , vol.79 , pp. 187-193
    • Akhter, W.1    Ashraf, Q.M.2    Zanelli, S.A.3    Mishra, O.P.4    Delivoria-Papadopoulos, M.5
  • 15
    • 0036155239 scopus 로고    scopus 로고
    • Nitration of Bax and Bcl-2 proteins during hypoxia in cerebral cortex of newborn piglets and the effect of nitric oxide synthase inhibition
    • Ashraf, Q. M., Zubrow, A. B., Mishra, O. P., and Delivoria-Papadopoulos, M. 2002. Nitration of Bax and Bcl-2 proteins during hypoxia in cerebral cortex of newborn piglets and the effect of nitric oxide synthase inhibition. Biol. Neonate. 81:65-72.
    • (2002) Biol. Neonate. , vol.81 , pp. 65-72
    • Ashraf, Q.M.1    Zubrow, A.B.2    Mishra, O.P.3    Delivoria-Papadopoulos, M.4
  • 16
    • 0036934616 scopus 로고    scopus 로고
    • Caspase-3 activation and caspase-like proteolytic activity in human perinatal hypoxicischemic brain injury
    • Berl.
    • Rossiter, J. P., Anderson, L. L., Yang, F., and Cole, G. M. 2002. Caspase-3 activation and caspase-like proteolytic activity in human perinatal hypoxicischemic brain injury. Acta Neuropathol. (Berl.) 103:66-73.
    • (2002) Acta Neuropathol. , vol.103 , pp. 66-73
    • Rossiter, J.P.1    Anderson, L.L.2    Yang, F.3    Cole, G.M.4
  • 18
    • 0024378999 scopus 로고
    • Nitric oxide mediates glutamate-linked enhancement of cGMP levels in the cerebellum
    • Bredt, D. S. and Snyder, S. H. 1989. Nitric oxide mediates glutamate-linked enhancement of cGMP levels in the cerebellum. Proc. Natl. Acad. Sci. USA 86:9030-9033.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 9030-9033
    • Bredt, D.S.1    Snyder, S.H.2
  • 20
    • 0016591230 scopus 로고
    • RNA polymerase activity in various classes of nuclei from different regions of rat brain during postnatal development
    • Guiffrida, A. M., Cox, D., and Mathias, A. P. 1975. RNA polymerase activity in various classes of nuclei from different regions of rat brain during postnatal development. J. Neurochem. 24:749-755.
    • (1975) J. Neurochem. , vol.24 , pp. 749-755
    • Guiffrida, A.M.1    Cox, D.2    Mathias, A.P.3
  • 21
    • 0015408250 scopus 로고
    • Fractionation of nuclei from brain by zonal centrifugation and a study of the ribonucleic acid polymerase activity in the various classes of nuclei
    • Austoker, J., Cox, D., and Mathias, A. P. 1972. Fractionation of nuclei from brain by zonal centrifugation and a study of the ribonucleic acid polymerase activity in the various classes of nuclei. Biochem. J. 129:1139-1155.
    • (1972) Biochem. J. , vol.129 , pp. 1139-1155
    • Austoker, J.1    Cox, D.2    Mathias, A.P.3
  • 22
    • 0028964318 scopus 로고
    • Purification of all forms of HeLa cell mitochondrial DNA and assessment of damage to it caused by hydrogen peroxide treatment of mitochondria or cells
    • Higuchi, Y. and Lynn, S. 1995. Purification of all forms of HeLa cell mitochondrial DNA and assessment of damage to it caused by hydrogen peroxide treatment of mitochondria or cells. J. Biol. Chem. 270:7950-7956.
    • (1995) J. Biol. Chem. , vol.270 , pp. 7950-7956
    • Higuchi, Y.1    Lynn, S.2
  • 25
    • 0032906975 scopus 로고    scopus 로고
    • Cellular mechanisms of hypoxic injury in the developing brain
    • Mishra, O. P. and Delivoria-Papadopoulos, M. 1999. Cellular mechanisms of hypoxic injury in the developing brain. Brain Res. Bull. 48:233-238.
    • (1999) Brain Res. Bull. , vol.48 , pp. 233-238
    • Mishra, O.P.1    Delivoria-Papadopoulos, M.2
  • 26
    • 0027294047 scopus 로고
    • Characterization of the novel nitric oxide synthase inhibitor 7-nitro indazole and related indazoles: Antinociceptive and cardiovascular effects
    • Moore, P. K., Wallace, P., Gaffen, Z., Hart, S. L., and Babbedge, R. C. 1993. Characterization of the novel nitric oxide synthase inhibitor 7-nitro indazole and related indazoles: Antinociceptive and cardiovascular effects. Br. J. Pharmacol. 110:219-224.
    • (1993) Br. J. Pharmacol. , vol.110 , pp. 219-224
    • Moore, P.K.1    Wallace, P.2    Gaffen, Z.3    Hart, S.L.4    Babbedge, R.C.5
  • 27
    • 0030795934 scopus 로고    scopus 로고
    • Selective inhibitors of neuronal nitric oxide synthase - Is no NOS really good NOS for the nervous system?
    • Moore, P. K., and Handy, R. L. C. 1997. Selective inhibitors of neuronal nitric oxide synthase - is no NOS really good NOS for the nervous system? Trends Pharmacol. 18:204-211.
    • (1997) Trends Pharmacol. , vol.18 , pp. 204-211
    • Moore, P.K.1    Handy, R.L.C.2
  • 29
    • 0035800586 scopus 로고    scopus 로고
    • Expression of endothelial nitric oxide synthase in the ischemic penumbra: Relationship to expression of neuronal nitric oxide synthase and vascular endothelial growth factor
    • Leker, R. R., Teichner, A., Ovadia, H., Keshet, E., Reinherz, E., and Ben-Hur, T. 2001. Expression of endothelial nitric oxide synthase in the ischemic penumbra: Relationship to expression of neuronal nitric oxide synthase and vascular endothelial growth factor. Brain Res. 909:1-7.
    • (2001) Brain Res. , vol.909 , pp. 1-7
    • Leker, R.R.1    Teichner, A.2    Ovadia, H.3    Keshet, E.4    Reinherz, E.5    Ben-Hur, T.6
  • 31
    • 0343060358 scopus 로고    scopus 로고
    • Roles of nitric oxide in brain hypoxia-ischemia
    • Bolanos, J. P. and Almeida, A. 1999. Roles of nitric oxide in brain hypoxia-ischemia. Biochem. Biophys. Acta 1411:415-436.
    • (1999) Biochem. Biophys. Acta , vol.1411 , pp. 415-436
    • Bolanos, J.P.1    Almeida, A.2
  • 32
    • 0037135265 scopus 로고    scopus 로고
    • Nitration is a mechanism of regulation of the NMDA receptor function during hypoxia
    • Zanelli, S. A., Ashraf, Q. M., and Mishra, O. P. 2002. Nitration is a mechanism of regulation of the NMDA receptor function during hypoxia. Neuroscience 112:869-877.
    • (2002) Neuroscience , vol.112 , pp. 869-877
    • Zanelli, S.A.1    Ashraf, Q.M.2    Mishra, O.P.3
  • 33
    • 0031666555 scopus 로고    scopus 로고
    • Involvement of Bcl-2 family and caspase-3-like protease in NO-mediated neuronal apoptosis
    • Tamatani, M., Ogawa, S., Niitsu, Y., and Tohyama, M. 1998. Involvement of Bcl-2 family and caspase-3-like protease in NO-mediated neuronal apoptosis. J. Neurochem. 71:1588-1596.
    • (1998) J. Neurochem. , vol.71 , pp. 1588-1596
    • Tamatani, M.1    Ogawa, S.2    Niitsu, Y.3    Tohyama, M.4
  • 34
    • 0036838504 scopus 로고    scopus 로고
    • Nitric oxide-mediated expression of Bax protein and DNA fragmentation during hypoxia in neuronal nuclei from newborn piglets
    • Zubrow, A. B., Delivoria-Papadopoulos, M., Ashraf, Q. M., Ballesteros, J. R., Fritz, K. I., and Mishra, O. P. 2001. Nitric oxide-mediated expression of Bax protein and DNA fragmentation during hypoxia in neuronal nuclei from newborn piglets. Brain Res. 954:60-67.
    • (2001) Brain Res. , vol.954 , pp. 60-67
    • Zubrow, A.B.1    Delivoria-Papadopoulos, M.2    Ashraf, Q.M.3    Ballesteros, J.R.4    Fritz, K.I.5    Mishra, O.P.6
  • 35
    • 0032724653 scopus 로고    scopus 로고
    • Caspase-3 is the primary activator of apoptotic DNA fragmentation via DNA fragmentation factor-45/Inhibitor of caspase-activated DNAse inactivation
    • Wolf, B. B., Schuler, M., Echeverri, F., and Green, D. R. 1999. Caspase-3 is the primary activator of apoptotic DNA fragmentation via DNA fragmentation factor-45/Inhibitor of caspase-activated DNAse inactivation. J. Biol. Chem. 274:30651-30656.
    • (1999) J. Biol. Chem. , vol.274 , pp. 30651-30656
    • Wolf, B.B.1    Schuler, M.2    Echeverri, F.3    Green, D.R.4
  • 36
    • 0031888955 scopus 로고    scopus 로고
    • A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD
    • Enari, M., Sakahira, H., Yokoyama, H., Okawa, K., Iwamatsu, A., and Nagata, S. 1998. A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD. Nature 391:43-50.
    • (1998) Nature , vol.391 , pp. 43-50
    • Enari, M.1    Sakahira, H.2    Yokoyama, H.3    Okawa, K.4    Iwamatsu, A.5    Nagata, S.6
  • 37
    • 0031889132 scopus 로고    scopus 로고
    • Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis
    • Sakahira, H., Enari, M., and Nagata, S. 1998. Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis. Nature 391:96-99.
    • (1998) Nature , vol.391 , pp. 96-99
    • Sakahira, H.1    Enari, M.2    Nagata, S.3
  • 38
    • 0030916417 scopus 로고    scopus 로고
    • DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis
    • Liu, X., Zou, H., Slaughter, C., and Wang, X. 1997. DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis. Cell 89:175-184.
    • (1997) Cell , vol.89 , pp. 175-184
    • Liu, X.1    Zou, H.2    Slaughter, C.3    Wang, X.4


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