메뉴 건너뛰기




Volumn 50, Issue 2, 1999, Pages 271-279

Maternal and developmental toxicity evaluation of melatonin administered orally to pregnant Sprague-Dawley rats

Author keywords

Development; Mammary gland; Melatonin; Pregnancy; Prenatal toxicity

Indexed keywords

ESTRADIOL; LUTEINIZING HORMONE; MELATONIN; PROGESTERONE; PROLACTIN;

EID: 0344069780     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/50.2.271     Document Type: Article
Times cited : (263)

References (68)
  • 2
    • 0000937686 scopus 로고
    • Test for linear trends in proportions and frequencies
    • Armitage, P. (1955). Test for linear trends in proportions and frequencies. Biometrics 11, 375-386.
    • (1955) Biometrics , vol.11 , pp. 375-386
    • Armitage, P.1
  • 3
    • 0028255909 scopus 로고
    • Effects of exogenous melatonin on prolactin secretion, lactogenesis, and reproductive seasonally of adult female red deer (Cervus elaphus)
    • Asher, G. W., Veldhuizen, F. A., Morrow, C. J., and Duganzich, D. M. (1994). Effects of exogenous melatonin on prolactin secretion, lactogenesis, and reproductive seasonally of adult female red deer (Cervus elaphus). J. Reprod. Fertil 100, 11-19.
    • (1994) J. Reprod. Fertil , vol.100 , pp. 11-19
    • Asher, G.W.1    Veldhuizen, F.A.2    Morrow, C.J.3    Duganzich, D.M.4
  • 4
    • 0002827887 scopus 로고
    • Hypothermia
    • L. Soma, Ed. Williams and Wilkins, Baltimore, MD
    • Blair, E. (1971). Hypothermia. In Textbook of Veterinary Anesthesia (L. Soma, Ed.), pp. 555-579. Williams and Wilkins, Baltimore, MD.
    • (1971) Textbook of Veterinary Anesthesia , pp. 555-579
    • Blair, E.1
  • 5
    • 0028178161 scopus 로고
    • Development of pre-implantation mouse embryos under the influence of pineal indoles
    • Chan, W. Y., and Ng, T. B. (1994). Development of pre-implantation mouse embryos under the influence of pineal indoles. J. Neural Transm. Gen. Sect. 96, 19-29.
    • (1994) J. Neural Transm. Gen. Sect. , vol.96 , pp. 19-29
    • Chan, W.Y.1    Ng, T.B.2
  • 6
    • 0029004088 scopus 로고
    • Changes induced by pineal indoles in post-implantation mouse embryos
    • Chan, W. Y., and Ng, T. B. (1995). Changes induced by pineal indoles in post-implantation mouse embryos. Gen. Pharmacol. 26, 1113-1118.
    • (1995) Gen. Pharmacol. , vol.26 , pp. 1113-1118
    • Chan, W.Y.1    Ng, T.B.2
  • 7
    • 0028216003 scopus 로고
    • Non-neoplastic renal lesions in Sprague-Dawley and Fischer-344 rats
    • Chandra, M., and Frith, C. H. (1993/1994), Non-neoplastic renal lesions in Sprague-Dawley and Fischer-344 rats. Exp. Toxicol. Pathol. 45, 439-447.
    • (1993) Exp. Toxicol. Pathol. , vol.45 , pp. 439-447
    • Chandra, M.1    Frith, C.H.2
  • 9
    • 0026056394 scopus 로고
    • Melatonin administration during pregnancy retards sexual maturation of female offspring in the rat
    • Colmenero, M. D., Díaz, B., Miguel, J. L., Gonzàlez, M. L. I., Esquifino, A., and Marín, B. (1991). Melatonin administration during pregnancy retards sexual maturation of female offspring in the rat. J. Pineal Res. 11, 23-27.
    • (1991) J. Pineal Res. , vol.11 , pp. 23-27
    • Colmenero, M.D.1    Díaz, B.2    Miguel, J.L.3    Gonzàlez, M.L.I.4    Esquifino, A.5    Marín, B.6
  • 10
    • 0029384970 scopus 로고
    • The clinical neuroimmunotherapeutic role of melatonin in oncology
    • Conti, A., and Maestroni, J. M. (1995). The clinical neuroimmunotherapeutic role of melatonin in oncology. J. Pineal Res. 19, 103-110.
    • (1995) J. Pineal Res. , vol.19 , pp. 103-110
    • Conti, A.1    Maestroni, J.M.2
  • 11
    • 0002444318 scopus 로고
    • Growth factors in mammary gland development and function
    • M. C. Neville and C. W. Daniel, Eds. Plenum Press, New York
    • Dembinski, T. C. and Shiu R. P. (1987) Growth factors in mammary gland development and function. In: The Mammary Gland: Development, Regulation, and Function (M. C. Neville and C. W. Daniel, Eds.), pp. 355-373. Plenum Press, New York.
    • (1987) The Mammary Gland: Development, Regulation, and Function , pp. 355-373
    • Dembinski, T.C.1    Shiu, R.P.2
  • 13
    • 0009663357 scopus 로고
    • A multiple comparison procedure for comparing several treatments with a control
    • Dunnett, C. W. (1955). A multiple comparison procedure for comparing several treatments with a control. J. Am. Stat. Assoc. 50, 1096-1121.
    • (1955) J. Am. Stat. Assoc. , vol.50 , pp. 1096-1121
    • Dunnett, C.W.1
  • 14
    • 0000080398 scopus 로고
    • New tables for multiple comparisons with a control
    • Dunnett, C. W. (1964). New tables for multiple comparisons with a control. Biometrics 20, 482-491.
    • (1964) Biometrics , vol.20 , pp. 482-491
    • Dunnett, C.W.1
  • 16
    • 0022624149 scopus 로고
    • Genetic control of melatonin synthesis in the pineal gland of mice
    • Ebihara, S., Marks, T., Hudson, D. J., Menaker, M. (1986). Genetic control of melatonin synthesis in the pineal gland of mice. Science 231, 491-493.
    • (1986) Science , vol.231 , pp. 491-493
    • Ebihara, S.1    Marks, T.2    Hudson, D.J.3    Menaker, M.4
  • 17
    • 0029132753 scopus 로고
    • Pineal gland and melatonin affect testicular status in the adult marsh rice rat (Oryzomys palustris)
    • Edmonds, K. E., and Stetson, M. H. (1995). Pineal gland and melatonin affect testicular status in the adult marsh rice rat (Oryzomys palustris). Gen. Comp. Endocrinol. 99, 265-274.
    • (1995) Gen. Comp. Endocrinol. , vol.99 , pp. 265-274
    • Edmonds, K.E.1    Stetson, M.H.2
  • 19
    • 0027429994 scopus 로고
    • The significance of the metabolism of the neurohormone melatonin: Antioxidative protection and formation of bioactive substances
    • Hardeland, R., Reiter, R. J., Poeggeler, B., and Tan, D.-X. (1993). The significance of the metabolism of the neurohormone melatonin: Antioxidative protection and formation of bioactive substances. Neurosci. Biobehav. Rev. 17, 347-357.
    • (1993) Neurosci. Biobehav. Rev. , vol.17 , pp. 347-357
    • Hardeland, R.1    Reiter, R.J.2    Poeggeler, B.3    Tan, D.-X.4
  • 20
    • 0029056752 scopus 로고
    • The effect of pregnancy on rat urinary tract dynamics
    • Hsia, T. Y., and Shortliffe, L. M. (1995). The effect of pregnancy on rat urinary tract dynamics. J. Urol. 154(2 Pt 2), 684-689.
    • (1995) J. Urol. , vol.154 , Issue.2 PART 2 , pp. 684-689
    • Hsia, T.Y.1    Shortliffe, L.M.2
  • 21
    • 0027313442 scopus 로고
    • The contribution of extrapineal sites of melatonin synthesis to circulating melatonin levels in higher vertebrates
    • Huether, G. (1993). The contribution of extrapineal sites of melatonin synthesis to circulating melatonin levels in higher vertebrates. Experientia 49, 665-670.
    • (1993) Experientia , vol.49 , pp. 665-670
    • Huether, G.1
  • 22
    • 0018942209 scopus 로고
    • Glomerular dynamics in rats with hereditary hydronephrosis
    • Humes, H. D., Dieppa, R. A., and Brenner, B. M. (1980). Glomerular dynamics in rats with hereditary hydronephrosis. Invest. Urol. 18, 46-51.
    • (1980) Invest. Urol. , vol.18 , pp. 46-51
    • Humes, H.D.1    Dieppa, R.A.2    Brenner, B.M.3
  • 23
    • 0013942077 scopus 로고
    • Influence of hormones on lobulo-alveolar differentiation of mouse mammary glands in vitro
    • Ichinose, R. R. and Nandi, S. (1966). Influence of hormones on lobulo-alveolar differentiation of mouse mammary glands in vitro. J. Endocrinol. 35, 331-340.
    • (1966) J. Endocrinol. , vol.35 , pp. 331-340
    • Ichinose, R.R.1    Nandi, S.2
  • 24
    • 0000941980 scopus 로고
    • A distribution-free k-sample test against ordered alternatives
    • Jonckheere, A. R. (1954). A distribution-free k-sample test against ordered alternatives. Biometrika 41, 133-145.
    • (1954) Biometrika , vol.41 , pp. 133-145
    • Jonckheere, A.R.1
  • 25
    • 0005918077 scopus 로고
    • Pineal function in pregnancy: Studies in sheep and man
    • C. D. Matthews and R. F Seamark, Eds., Elsevier/North-Holland Biomedical Press, New York
    • Kennaway, D. J., Matthews, C. D., and Seamark, R. F. (1981). Pineal function in pregnancy: Studies in sheep and man. In: Pineal Function (C. D. Matthews and R. F Seamark, Eds.), pp. 123-136, Elsevier/North-Holland Biomedical Press, New York.
    • (1981) Pineal Function , pp. 123-136
    • Kennaway, D.J.1    Matthews, C.D.2    Seamark, R.F.3
  • 26
    • 0021747849 scopus 로고
    • Daily afternoon administration of melatonin does not irrevers-ibly inhibit sexual maturation in the male rat
    • Lang, U., Aubert, M. L., Rivest, R. W., Vinas-Bradtke, J. C., and Sizonenko, P. C. (1984). Daily afternoon administration of melatonin does not irrevers-ibly inhibit sexual maturation in the male rat. Endocrinology 115, 2303-2310.
    • (1984) Endocrinology , vol.115 , pp. 2303-2310
    • Lang, U.1    Aubert, M.L.2    Rivest, R.W.3    Vinas-Bradtke, J.C.4    Sizonenko, P.C.5
  • 27
    • 0005715010 scopus 로고
    • Anesthesia in laboratory and zoo animals
    • Lea and Febiger, Philadelphia
    • Lumb, W. V., and Jones, E. W. (1973). Anesthesia in laboratory and zoo animals. In Veterinary Anesthesia, pp. 452-453. Lea and Febiger, Philadelphia.
    • (1973) Veterinary Anesthesia , pp. 452-453
    • Lumb, W.V.1    Jones, E.W.2
  • 28
    • 0000799322 scopus 로고
    • Comparison of single and double staining for evaluation of skeletal development: The effects of ethylene glycol (EG) in CD rats
    • Marr, M. C., Myers, C. B., George, J. D., and Price, C. J. (1988). Comparison of single and double staining for evaluation of skeletal development: The effects of ethylene glycol (EG) in CD rats. Teratology 37, 476.
    • (1988) Teratology , vol.37 , pp. 476
    • Marr, M.C.1    Myers, C.B.2    George, J.D.3    Price, C.J.4
  • 29
    • 0026325588 scopus 로고
    • Circadian myometrial and endocrine rhythms in the pregnant rhesus macaque: Effects of constant light and timed melatonin infusion
    • Matsumoto, T., Hess, D. L., Kaushal, K. M., Valenzuela, G. J., Yellon, S. M., and Ducsay, C. A. (1991). Circadian myometrial and endocrine rhythms in the pregnant rhesus macaque: Effects of constant light and timed melatonin infusion. Am J. Obstet. Gynecol. 165, 1777-1784.
    • (1991) Am J. Obstet. Gynecol. , vol.165 , pp. 1777-1784
    • Matsumoto, T.1    Hess, D.L.2    Kaushal, K.M.3    Valenzuela, G.J.4    Yellon, S.M.5    Ducsay, C.A.6
  • 30
    • 0030207941 scopus 로고    scopus 로고
    • The effect of melatonin on cleavage rate of C57BL/6 and CBA/Ca preimplantation embryos cultured in vitro
    • McElhinny, A. S., Davis, F. C., and Warner, C. M. (1996). The effect of melatonin on cleavage rate of C57BL/6 and CBA/Ca preimplantation embryos cultured in vitro. J. Pineal Res. 21, 44-48.
    • (1996) J. Pineal Res. , vol.21 , pp. 44-48
    • McElhinny, A.S.1    Davis, F.C.2    Warner, C.M.3
  • 31
    • 0024546568 scopus 로고
    • Maternal pinealectomy abolishes the diurnal rhythm in plasma melatonin concentrations in the fetal sheep and pregnant ewe during late gestation
    • McMillen, I. C., and Nowak, R. (1988). Maternal pinealectomy abolishes the diurnal rhythm in plasma melatonin concentrations in the fetal sheep and pregnant ewe during late gestation. J. Endocrinol. 120, 459-464.
    • (1988) J. Endocrinol. , vol.120 , pp. 459-464
    • McMillen, I.C.1    Nowak, R.2
  • 32
    • 0027725205 scopus 로고
    • Distribution of melatonin in mammalian tissues: The relative importance of nuclear versus cytosolic localization
    • Menendez-Pelaez, A., and Reiter, R. J. (1993). Distribution of melatonin in mammalian tissues: The relative importance of nuclear versus cytosolic localization. J. Pineal Res. 15, 59-69.
    • (1993) J. Pineal Res. , vol.15 , pp. 59-69
    • Menendez-Pelaez, A.1    Reiter, R.J.2
  • 33
    • 0017704893 scopus 로고
    • The effects of melatonin on skin color and on the release of pituitary hormones
    • Nordlund, J. J., and Lemer, A. B. (1977). The effects of melatonin on skin color and on the release of pituitary hormones. J. Clin. Endocrinol. Metab. 45, 768-774.
    • (1977) J. Clin. Endocrinol. Metab. , vol.45 , pp. 768-774
    • Nordlund, J.J.1    Lemer, A.B.2
  • 34
    • 0344152345 scopus 로고    scopus 로고
    • (CAS No. 73-31-4) Administered by Gavage to Sprague-Dawley (CD*) Rats on Gestational Days 6 through 19. NTP Study No. TRP-97-001. NTP/ NIEHS Contract No. NO1-ES-65405. Final Study Report, June 25, 1997
    • NTP (1997). Developmental Toxicity Screen for Melatonin (CAS No. 73-31-4) Administered by Gavage to Sprague-Dawley (CD*) Rats on Gestational Days 6 through 19. NTP Study No. TRP-97-001. NTP/ NIEHS Contract No. NO1-ES-65405. Final Study Report, June 25, 1997.
    • (1997) Developmental Toxicity Screen for Melatonin
  • 35
    • 0345446009 scopus 로고    scopus 로고
    • (CAS No. 73-31-4) Administered by Gavage to Sprague-Dawley (CD®) Rats on Gestational Days 6 through 19. NTP Study No. TER-96-003. NTP/NIEHS Contract No. N01-ES-65405. Final Study Report (NTIS Accession Number PB98-137300), March 31, 1998
    • NTP (1998). Developmental Toxicity Evaluation of Melatonin (CAS No. 73-31-4) Administered by Gavage to Sprague-Dawley (CD®) Rats on Gestational Days 6 through 19. NTP Study No. TER-96-003. NTP/NIEHS Contract No. N01-ES-65405. Final Study Report (NTIS Accession Number PB98-137300), March 31, 1998.
    • (1998) Developmental Toxicity Evaluation of Melatonin
  • 36
    • 0024948609 scopus 로고
    • Testicular function of sexually immature rats chronically treated with melatonin
    • Olivares, A. N., Valladares, L. E., Bustos-Obregon, E., and Nunez, S. M. (1989). Testicular function of sexually immature rats chronically treated with melatonin. Arch. Biol. Med. Exp. 22, 387-393.
    • (1989) Arch. Biol. Med. Exp. , vol.22 , pp. 387-393
    • Olivares, A.N.1    Valladares, L.E.2    Bustos-Obregon, E.3    Nunez, S.M.4
  • 37
    • 0023158432 scopus 로고
    • Plasma levels of immunoreactive melatonin, estradiol, progesterone, follicle stimulating hormone, and beta-human chorionic gonadotropin during pregnancy and shortly after parturition in humans
    • Pang, S. F., Tang, P. L., Tang, G. W. K., Yam, A. W. C., and Ng, K. W. (1987). Plasma levels of immunoreactive melatonin, estradiol, progesterone, follicle stimulating hormone, and beta-human chorionic gonadotropin during pregnancy and shortly after parturition in humans. J. Pineal Res. 4, 21-31.
    • (1987) J. Pineal Res. , vol.4 , pp. 21-31
    • Pang, S.F.1    Tang, P.L.2    Tang, G.W.K.3    Yam, A.W.C.4    Ng, K.W.5
  • 38
    • 0027026447 scopus 로고
    • Endocrine manipulation - Toxicological frontiers
    • Peters, A. R. (1992). Endocrine manipulation - toxicological frontiers. J. Reprod. Fertil. 45(suppl.), 193-201.
    • (1992) J. Reprod. Fertil. , vol.45 , Issue.SUPPL. , pp. 193-201
    • Peters, A.R.1
  • 39
    • 0025758136 scopus 로고
    • Pineal melatonin: Cell biology of its synthesis and of its physiological interactions
    • Reiter, R. J. (1991). Pineal melatonin: Cell biology of its synthesis and of its physiological interactions. Endocr. Rev. 12, 151-180.
    • (1991) Endocr. Rev. , vol.12 , pp. 151-180
    • Reiter, R.J.1
  • 40
    • 0004436059 scopus 로고
    • A master sex hormone, and taking melatonin supplements
    • R. J. Reiter and J. Robinson, Eds. Bantam Books, New York
    • Reiter, R. J., and Robinson, J. (1995). A master sex hormone, and Taking melatonin supplements. In Melatonin (R. J. Reiter and J. Robinson, Eds.), pp. 158-171 and 265-281. Bantam Books, New York.
    • (1995) Melatonin , pp. 158-171
    • Reiter, R.J.1    Robinson, J.2
  • 41
    • 0018419710 scopus 로고
    • Maternalfetal transfer of melatonin in the nonhuman primate
    • Reppert, S. M., Chez, R. A., Anderson, A., and Klein, D. C. (1979). Maternalfetal transfer of melatonin in the nonhuman primate. Pediatr. Res. 13, 788-791.
    • (1979) Pediatr. Res. , vol.13 , pp. 788-791
    • Reppert, S.M.1    Chez, R.A.2    Anderson, A.3    Klein, D.C.4
  • 43
    • 0023408076 scopus 로고
    • The female rat as a model describing patterns of pulsatile lh secretion during puberty and their control by melatonin
    • Rivest, R. W. (1987). The female rat as a model describing patterns of pulsatile LH secretion during puberty and their control by melatonin. Gynecol. Endocrinol. 1, 279-293.
    • (1987) Gynecol. Endocrinol. , vol.1 , pp. 279-293
    • Rivest, R.W.1
  • 44
    • 0022523810 scopus 로고
    • Puberty in the rat: Modulation by melatonin and light
    • Rivest, R. W., Aubert, M. L., Lang, U., and Sizonenko, P. C. (1986). Puberty in the rat: modulation by melatonin and light. J. Neural. Transm. 21(suppl.), 81-108.
    • (1986) J. Neural. Transm. , vol.21 , Issue.SUPPL. , pp. 81-108
    • Rivest, R.W.1    Aubert, M.L.2    Lang, U.3    Sizonenko, P.C.4
  • 45
    • 0021996809 scopus 로고
    • Daily administration of melatonin delays rat vaginal opening and disrupts the first estrous cycles: Evidence that these effects are synchronized by the onset of light
    • Rivest, R. W., Lang, U., Aubert, M. L., and Sizonenko, P. C. (1985). Daily administration of melatonin delays rat vaginal opening and disrupts the first estrous cycles: Evidence that these effects are synchronized by the onset of light. Endocrinology 116, 779-787.
    • (1985) Endocrinology , vol.116 , pp. 779-787
    • Rivest, R.W.1    Lang, U.2    Aubert, M.L.3    Sizonenko, P.C.4
  • 46
    • 0002810930 scopus 로고
    • Treatment of human metastatic malignant melanoma with high dose oral melatonin
    • F. Fraschini, R. J. Reiter, and B. Stankov, Eds. Plenum Press, New York
    • Robinson, W. A., Dreiling, L., Gonzalez, R., and Balmer, C. (1995). Treatment of human metastatic malignant melanoma with high dose oral melatonin. In The Pineal Gland and its Hormones: Fundamentals and Clinical Perspectives (F. Fraschini, R. J. Reiter, and B. Stankov, Eds.), pp. 219-225. Plenum Press, New York.
    • (1995) The Pineal Gland and Its Hormones: Fundamentals and Clinical Perspectives , pp. 219-225
    • Robinson, W.A.1    Dreiling, L.2    Gonzalez, R.3    Balmer, C.4
  • 47
    • 0029741983 scopus 로고    scopus 로고
    • The pineal gland and cancer
    • Ronco, A. L., and Halberg, F. (1996). The pineal gland and cancer. Anticancer Res. 16, 2033-2039.
    • (1996) Anticancer Res. , vol.16 , pp. 2033-2039
    • Ronco, A.L.1    Halberg, F.2
  • 48
    • 34250974627 scopus 로고
    • Farbemethode zum makroskopischen nachweis von implantationsstellen am uterus der ratte
    • Salewski, E. (1964). Farbemethode zum makroskopischen Nachweis von Implantationsstellen am Uterus der Ratte. Naunyn-Schmiedebergs Arch. Exp. Pathol. Pharmakol. 247, 367.
    • (1964) Naunyn-schmiedebergs Arch. Exp. Pathol. Pharmakol. , vol.247 , pp. 367
    • Salewski, E.1
  • 49
    • 0025298677 scopus 로고
    • Influence of melatonin on the mammary gland growth: In vivo and in vitro studies
    • Sanchez-Barcelo, E. J., Mediavilla, M. D., and Tucker, H. A. (1990). Influence of melatonin on the mammary gland growth: In vivo and in vitro studies. Proc. Soc. Exp. Biol. Med. 194, 103-107.
    • (1990) Proc. Soc. Exp. Biol. Med. , vol.194 , pp. 103-107
    • Sanchez-Barcelo, E.J.1    Mediavilla, M.D.2    Tucker, H.A.3
  • 54
    • 0003064131 scopus 로고
    • Detection of visceral alterations in mammalian fetuses
    • Staples, R. E. (1974). Detection of visceral alterations in mammalian fetuses. Teratology 9, 7.
    • (1974) Teratology , vol.9 , pp. 7
    • Staples, R.E.1
  • 55
    • 0021637726 scopus 로고
    • Fresh visceral examination of rat and rabbit fetuses used in teratogenicity testing
    • Stuckhardt, J. L., and Poppe, S. M. (1984). Fresh visceral examination of rat and rabbit fetuses used in teratogenicity testing. Teratog. Carcinog. Mutagen. 4, 181-188.
    • (1984) Teratog. Carcinog. Mutagen. , vol.4 , pp. 181-188
    • Stuckhardt, J.L.1    Poppe, S.M.2
  • 56
    • 0016725610 scopus 로고
    • The effect of the pineal gland on ovulation and pregnancy in the rat
    • Tigchelaar, P. V., and Nalbandov, A. V. (1975). The effect of the pineal gland on ovulation and pregnancy in the rat. Biol. Reprod. 13, 461-469.
    • (1975) Biol. Reprod. , vol.13 , pp. 461-469
    • Tigchelaar, P.V.1    Nalbandov, A.V.2
  • 57
    • 0002611499 scopus 로고    scopus 로고
    • Developmental toxicity testing: Methodology
    • R. D. Hood, Ed. CRC Press, New York
    • Tyl, R. W., and Marr, M. C. (1997). Developmental toxicity testing: Methodology. In Handbook of Developmental Toxicology (R. D. Hood, Ed.), pp. 175-225. CRC Press, New York.
    • (1997) Handbook of Developmental Toxicology , pp. 175-225
    • Tyl, R.W.1    Marr, M.C.2
  • 58
    • 0024065070 scopus 로고
    • Incidence of hydronephrosis among several production colonies of outbred Sprague-Dawley rats
    • Van Winkle, T. J., Womack, J. E., Barbo, W. D., and Davis, T. W. (1988). Incidence of hydronephrosis among several production colonies of outbred Sprague-Dawley rats. Lab. Anim. Sci. 38, 402-406.
    • (1988) Lab. Anim. Sci. , vol.38 , pp. 402-406
    • Van Winkle, T.J.1    Womack, J.E.2    Barbo, W.D.3    Davis, T.W.4
  • 59
    • 0014713516 scopus 로고
    • Estrous cycle changes after prenatal and neonatal injections of melatonin in normal and androgen-sterilized female rats
    • Vaughan, M. K., O'Steen, W. K., and Vaughan, G. M. (1970). Estrous cycle changes after prenatal and neonatal injections of melatonin in normal and androgen-sterilized female rats. Neuroendocrinology 6, 10-18.
    • (1970) Neuroendocrinology , vol.6 , pp. 10-18
    • Vaughan, M.K.1    O'Steen, W.K.2    Vaughan, G.M.3
  • 60
    • 0017083846 scopus 로고
    • Fertility patterns in female mice following treatment with arginine vasotocin or melatonin
    • Vaughan, M. K., Reiter, R. J., and Vaughan, G. M. (1976). Fertility patterns in female mice following treatment with arginine vasotocin or melatonin. Int. J. Fert. 21, 65-68.
    • (1976) Int. J. Fert. , vol.21 , pp. 65-68
    • Vaughan, M.K.1    Reiter, R.J.2    Vaughan, G.M.3
  • 61
    • 0026542361 scopus 로고
    • Evidence that circadian variations of circulating melatonin levels in fetal and suckling rats are dependent on maternal melatonin transfer
    • Velàzquez, E., Esquifino, A. I., Zueco, J. A., Ruiz Albusac, J. M., and Blazquez. E. (1992). Evidence that circadian variations of circulating melatonin levels in fetal and suckling rats are dependent on maternal melatonin transfer. Neuroendocrinology 55, 321-326.
    • (1992) Neuroendocrinology , vol.55 , pp. 321-326
    • Velàzquez, E.1    Esquifino, A.I.2    Zueco, J.A.3    Ruiz Albusac, J.M.4    Blazquez, E.5
  • 62
    • 0003119852 scopus 로고
    • Prolactin: Transport, function, and receptors in mammary gland development and differentiation
    • M. C. Neville and C. W. Daniel, Eds. Plenum Press, New York City
    • Vonderhaar, B.K. (1987). Prolactin: Transport, function, and receptors in mammary gland development and differentiation. In The Mammary Gland: Development, Regulation, and Function (M. C. Neville and C. W. Daniel, Eds.) pp. 383-417. Plenum Press, New York City.
    • (1987) The Mammary Gland: Development, Regulation, and Function , pp. 383-417
    • Vonderhaar, B.K.1
  • 64
    • 0020037025 scopus 로고
    • Melatonin and the influence of the pineal gland on timing of the LH surge in rats
    • Walker, R. F., McCamant, S., and Timiras, P. S. (1982). Melatonin and the influence of the pineal gland on timing of the LH surge in rats. Neuroendoerinology 35, 37-42.
    • (1982) Neuroendoerinology , vol.35 , pp. 37-42
    • Walker, R.F.1    McCamant, S.2    Timiras, P.S.3
  • 66
    • 0002990833 scopus 로고
    • Embryological considerations in teratology
    • J. G. Wilson and J. Warkany, Eds. University of Chicago Press, Chicago, IL
    • Wilson, J. G. (1965). Embryological considerations in teratology. In Teratology: Principals and Techniques (J. G. Wilson and J. Warkany, Eds.), pp. 251-277. University of Chicago Press, Chicago, IL.
    • (1965) Teratology: Principals and Techniques , pp. 251-277
    • Wilson, J.G.1
  • 68
    • 0015545409 scopus 로고
    • Inhibition of ovulation by melatonin in the cyclic rat
    • Ying, S.-Y., and Greep, R. O. (1973). Inhibition of ovulation by melatonin in the cyclic rat. Endocrinology 92, 333-335.
    • (1973) Endocrinology , vol.92 , pp. 333-335
    • Ying, S.-Y.1    Greep, R.O.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.