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Volumn 124, Issue 2, 2009, Pages

Erythropoietin improved neurologic outcomes in newborns with hypoxic-ischemic encephalopathy

Author keywords

Asphyxia; Erythropoietin; Hypoxic ischemic encephalopathy; Neonates

Indexed keywords

ERYTHROPOIETIN; RECOMBINANT ERYTHROPOIETIN;

EID: 67749137294     PISSN: 00314005     EISSN: 10984275     Source Type: Journal    
DOI: 10.1542/peds.2008-3553     Document Type: Article
Times cited : (300)

References (45)
  • 1
    • 0036112347 scopus 로고    scopus 로고
    • Mechanisms of hypoxic neurodegeneration in the developing brain
    • Johnston MV, Nakajima W, Hagberg H. Mechanisms of hypoxic neurodegeneration in the developing brain. Neuroscientist. 2002;8(3):212-220
    • (2002) Neuroscientist , vol.8 , Issue.3 , pp. 212-220
    • Johnston, M.V.1    Nakajima, W.2    Hagberg, H.3
  • 2
    • 26444452073 scopus 로고    scopus 로고
    • Whole-body hypothermia for neonates with hypoxic-ischemic encephalopathy
    • Shankaran S, Laptook AR, Ehrenkranz RA, et al. Whole-body hypothermia for neonates with hypoxic-ischemic encephalopathy. N Engl J Med. 2005;353(15):1574 -1584
    • (2005) N Engl J Med , vol.353 , Issue.15 , pp. 1574-1584
    • Shankaran, S.1    Laptook, A.R.2    Ehrenkranz, R.A.3
  • 3
    • 13844321255 scopus 로고    scopus 로고
    • Selective head cooling with mild systemic hypothermia after neonatal encephalopathy: Multicentre randomised trial
    • Gluckman PD, Wyatt JS, Azzopardi D, et al. Selective head cooling with mild systemic hypothermia after neonatal encephalopathy: multicentre randomised trial. Lancet. 2005;365(9460):663- 670
    • (2005) Lancet , vol.365 , Issue.9460 , pp. 663-670
    • Gluckman, P.D.1    Wyatt, J.S.2    Azzopardi, D.3
  • 4
    • 0031789208 scopus 로고    scopus 로고
    • Neuroprotection with prolonged head cooling started before postischemic seizures in fetal sheep
    • Gunn AJ, Gunn TR, Gunning MI, Williams CE, Gluckman PD. Neuroprotection with prolonged head cooling started before postischemic seizures in fetal sheep. Pediatrics. 1998;102(5): 1098 -1106
    • (1998) Pediatrics , vol.102 , Issue.5 , pp. 1098-1106
    • Gunn, A.J.1    Gunn, T.R.2    Gunning, M.I.3    Williams, C.E.4    Gluckman, P.D.5
  • 5
    • 84965084773 scopus 로고
    • The influence of the thermal environment upon the survival of newly born premature infants
    • Silverman WA, Fertig JW, Berger AP. The influence of the thermal environment upon the survival of newly born premature infants. Pediatrics. 1958;22(5):876-886
    • (1958) Pediatrics , vol.22 , Issue.5 , pp. 876-886
    • Silverman, W.A.1    Fertig, J.W.2    Berger, A.P.3
  • 6
    • 0028210933 scopus 로고
    • The effect of epoetin β(recombinant human erythropoietin) on the need for transfusion in very-low-birth-weight infants
    • Maier RF, Obladen M, Scigalla P, et al. The effect of epoetin β(recombinant human erythropoietin) on the need for transfusion in very-low-birth-weight infants. N Engl J Med. 1994;330(17):1173-1178
    • (1994) N Engl J Med , vol.330 , Issue.17 , pp. 1173-1178
    • Maier, R.F.1    Obladen, M.2    Scigalla, P.3
  • 7
    • 16244423165 scopus 로고    scopus 로고
    • Neurodevelopmental outcome and growth at 18 to 22 months' corrected age in extremely low birth weight infants treated with early erythropoietin and iron
    • Ohls RK, Ehrenkranz RA, Das A, et al. Neurodevelopmental outcome and growth at 18 to 22 months' corrected age in extremely low birth weight infants treated with early erythropoietin and iron. Pediatrics. 2004;114(5):1287-1291
    • (2004) Pediatrics , vol.114 , Issue.5 , pp. 1287-1291
    • Ohls, R.K.1    Ehrenkranz, R.A.2    Das, A.3
  • 8
    • 0034641710 scopus 로고    scopus 로고
    • Erythropoietin crosses the blood-brain barrier to protect against experimental brain injury
    • Brines ML, Ghezzi P, Keenan S, et al. Erythropoietin crosses the blood-brain barrier to protect against experimental brain injury. Proc Natl Acad Sci U S A. 2000;97(19):10526 -10531
    • (2000) Proc Natl Acad Sci U S A , vol.97 , Issue.19 , pp. 10526-10531
    • Brines, M.L.1    Ghezzi, P.2    Keenan, S.3
  • 9
    • 40649100555 scopus 로고    scopus 로고
    • High levels of erythropoietin are associated with protection against neurological sequelae in African children with cerebral malaria
    • Casals-Pascual C, Idro R, Gicheru N, et al. High levels of erythropoietin are associated with protection against neurological sequelae in African children with cerebral malaria. Proc Natl Acad Sci U S A. 2008;105(7):2634 -2639
    • (2008) Proc Natl Acad Sci U S A , vol.105 , Issue.7 , pp. 2634-2639
    • Casals-Pascual, C.1    Idro, R.2    Gicheru, N.3
  • 10
    • 8644228438 scopus 로고    scopus 로고
    • The nonerythropoietic asialoerythropoietin protects against neonatal hypoxia-ischemia as potently as erythropoietin
    • Wang X, Zhu C, Wang X, et al. The nonerythropoietic asialoerythropoietin protects against neonatal hypoxia-ischemia as potently as erythropoietin. J Neurochem. 2004;91(4):900 -910
    • (2004) J Neurochem , vol.91 , Issue.4 , pp. 900-910
    • Wang, X.1    Zhu, C.2    Wang, X.3
  • 11
    • 17844393791 scopus 로고    scopus 로고
    • Erythropoietin improves functional and histological outcome in neonatal stroke
    • Chang YS, Mu D, Wendland M, et al. Erythropoietin improves functional and histological outcome in neonatal stroke. Pediatr Res. 2005;58(1):106 -111
    • (2005) Pediatr Res , vol.58 , Issue.1 , pp. 106-111
    • Chang, Y.S.1    Mu, D.2    Wendland, M.3
  • 12
    • 33846428477 scopus 로고    scopus 로고
    • Safety of high-dose recombinant erythropoietin in a neonatal rat model
    • McPherson RJ, Demers EJ, Juul SE. Safety of high-dose recombinant erythropoietin in a neonatal rat model. Neonatology. 2007;91(1):36-43
    • (2007) Neonatology , vol.91 , Issue.1 , pp. 36-43
    • McPherson, R.J.1    Demers, E.J.2    Juul, S.E.3
  • 13
    • 33646121270 scopus 로고    scopus 로고
    • Gender differences in long-term beneficial effects of erythropoietin given after neonatal stroke in postnatal day-7 rats
    • Wen TC, Rogido M, Peng H, Genetta T, Moore J, Sola A. Gender differences in long-term beneficial effects of erythropoietin given after neonatal stroke in postnatal day-7 rats. Neuroscience. 2006; 139(3):803- 811
    • (2006) Neuroscience , vol.139 , Issue.3 , pp. 803-811
    • Wen, T.C.1    Rogido, M.2    Peng, H.3    Genetta, T.4    Moore, J.5    Sola, A.6
  • 14
    • 33646099794 scopus 로고    scopus 로고
    • Erythropoietin concentrations and neurodevelopmental outcome in preterm infants
    • Available at
    • Bierer R, Peceny MC, Hartenberger CH, Ohls RK. Erythropoietin concentrations and neurodevelopmental outcome in preterm infants. Pediatrics. 2006;118(3). Available at: www.pediatrics.org/cgi/ content/full/118/3/e635
    • (2006) Pediatrics , vol.118 , Issue.3
    • Bierer, R.1    Peceny, M.C.2    Hartenberger, C.H.3    Ohls, R.K.4
  • 15
    • 0036705708 scopus 로고    scopus 로고
    • Erythropoietin therapy for acute stroke is both safe and beneficial
    • Ehrenreich H, Hasselblatt M, Dembowski C, et al. Erythropoietin therapy for acute stroke is both safe and beneficial. Mol Med. 2002;8(8):495-505
    • (2002) Mol Med , vol.8 , Issue.8 , pp. 495-505
    • Ehrenreich, H.1    Hasselblatt, M.2    Dembowski, C.3
  • 16
    • 0034192225 scopus 로고    scopus 로고
    • Effects of erythropoietin on platelet reactivity and thrombopoiesis in humans
    • Stohlawetz PJ, Dzirlo L, Hergovich N, et al. Effects of erythropoietin on platelet reactivity and thrombopoiesis in humans. Blood. 2000;95(9):2983-2989
    • (2000) Blood , vol.95 , Issue.9 , pp. 2983-2989
    • Stohlawetz, P.J.1    Dzirlo, L.2    Hergovich, N.3
  • 17
    • 0017199855 scopus 로고
    • Neonatal encephalopathy following fetal distress: A clinical and electroencephalographic study
    • Sarnat HB, Sarnat MS. Neonatal encephalopathy following fetal distress: a clinical and electroencephalographic study. Arch Neurol. 1976;33(10):696 -705
    • (1976) Arch Neurol , vol.33 , Issue.10 , pp. 696-705
    • Sarnat, H.B.1    Sarnat, M.S.2
  • 18
    • 0030751162 scopus 로고    scopus 로고
    • The value of a scoring system for hypoxic ischaemic encephalopathy in predicting neurodevelopmental outcome
    • Thompson CM, Puterman AS, Linley LL, et al. The value of a scoring system for hypoxic ischaemic encephalopathy in predicting neurodevelopmental outcome. Acta Paediatr. 1997;86(7):757-761
    • (1997) Acta Paediatr , vol.86 , Issue.7 , pp. 757-761
    • Thompson, C.M.1    Puterman, A.S.2    Linley, L.L.3
  • 19
    • 0022545237 scopus 로고
    • Birth asphyxia in the full-term newborn: Early assessment and outcome
    • Amiel-Tison C, Ellison P. Birth asphyxia in the full-term newborn: early assessment and outcome. Dev Med Child Neurol. 1986;28(5):671- 682
    • (1986) Dev Med Child Neurol , vol.28 , Issue.5 , pp. 671-682
    • Amiel-Tison, C.1    Ellison, P.2
  • 20
    • 0027571364 scopus 로고
    • 20-item neonatal behavioral neurological assessment used in predicting prognosis of asphyxiated newborn
    • Bao XL, Yu RJ, Li ZS. 20-item neonatal behavioral neurological assessment used in predicting prognosis of asphyxiated newborn. Chin Med J (Engl). 1993;106(3):211-215
    • (1993) Chin Med J (Engl) , vol.106 , Issue.3 , pp. 211-215
    • Bao, X.L.1    Yu, R.J.2    Li, Z.S.3
  • 21
    • 0030988386 scopus 로고    scopus 로고
    • Development and reliability of a system to classify gross motor function in children with cerebral palsy
    • Palisano R, Rosenbaum P, Walter S, Russell D, Wood E, Galuppi B. Development and reliability of a system to classify gross motor function in children with cerebral palsy. Dev Med Child Neurol. 1997;39(4):214 -223
    • (1997) Dev Med Child Neurol , vol.39 , Issue.4 , pp. 214-223
    • Palisano, R.1    Rosenbaum, P.2    Walter, S.3    Russell, D.4    Wood, E.5    Galuppi, B.6
  • 22
    • 0003499725 scopus 로고
    • Second Edition. San Antonio, TX: The Psychological Corporation;
    • Bayley N. Bayley Scales of Infant Development, Second Edition. San Antonio, TX: The Psychological Corporation; 1993
    • (1993) Bayley Scales of Infant Development
    • Bayley, N.1
  • 23
    • 19944404414 scopus 로고    scopus 로고
    • Moderate hypothermia in neonatal encephalopathy: Efficacy outcomes
    • Eicher DJ, Wagner CL, Katikaneni LP, et al. Moderate hypothermia in neonatal encephalopathy: efficacy outcomes. Pediatr Neurol. 2005;32(1):11-17
    • (2005) Pediatr Neurol , vol.32 , Issue.1 , pp. 11-17
    • Eicher, D.J.1    Wagner, C.L.2    Katikaneni, L.P.3
  • 24
    • 34147098024 scopus 로고    scopus 로고
    • A comparison of high-dose recombinant erythropoietin treatment regimens in brain-injured neonatal rats
    • Kellert BA, McPherson RJ, Juul SE. A comparison of high-dose recombinant erythropoietin treatment regimens in brain-injured neonatal rats. Pediatr Res. 2007;61(4):451- 455
    • (2007) Pediatr Res , vol.61 , Issue.4 , pp. 451-455
    • Kellert, B.A.1    McPherson, R.J.2    Juul, S.E.3
  • 25
    • 33847203208 scopus 로고    scopus 로고
    • Reduced functional deficits, neuroinflammation, and secondary tissue damage after treatment of stroke by nonerythropoietic erythropoietin derivatives
    • Villa P, van Beek J, Larsen AK, et al. Reduced functional deficits, neuroinflammation, and secondary tissue damage after treatment of stroke by nonerythropoietic erythropoietin derivatives. J Cereb Blood Flow Metab. 2007;27(3):552-563
    • (2007) J Cereb Blood Flow Metab , vol.27 , Issue.3 , pp. 552-563
    • Villa, P.1    van Beek, J.2    Larsen, A.K.3
  • 26
    • 33750107287 scopus 로고    scopus 로고
    • Erythropoietin is neuroprotective against NMDA-receptormediated excitotoxic brain injury in newborn mice
    • Keller M, Yang J, Griesmaier E, et al. Erythropoietin is neuroprotective against NMDA-receptormediated excitotoxic brain injury in newborn mice. Neurobiol Dis. 2006;24(2):357-366
    • (2006) Neurobiol Dis , vol.24 , Issue.2 , pp. 357-366
    • Keller, M.1    Yang, J.2    Griesmaier, E.3
  • 28
    • 1842613593 scopus 로고    scopus 로고
    • Erythropoietin concentrations in cerebrospinal fluid of nonhuman primates and fetal sheep following high-dose recombinant erythropoietin
    • Juul SE, McPherson RJ, Farrell FX, Jolliffe L, Ness DJ, Gleason CA. Erythropoietin concentrations in cerebrospinal fluid of nonhuman primates and fetal sheep following high-dose recombinant erythropoietin. Biol Neonate. 2004;85(2):138 -144
    • (2004) Biol Neonate , vol.85 , Issue.2 , pp. 138-144
    • Juul, S.E.1    McPherson, R.J.2    Farrell, F.X.3    Jolliffe, L.4    Ness, D.J.5    Gleason, C.A.6
  • 29
    • 20044369962 scopus 로고    scopus 로고
    • The pharmacokinetics of erythropoietin in the cerebrospinal fluid after intravenous administration of recombinant human erythropoietin
    • Xenocostas A, Cheung WK, Farrell F, et al. The pharmacokinetics of erythropoietin in the cerebrospinal fluid after intravenous administration of recombinant human erythropoietin. Eur J Clin Pharmacol. 2005;61(3):189 -195
    • (2005) Eur J Clin Pharmacol , vol.61 , Issue.3 , pp. 189-195
    • Xenocostas, A.1    Cheung, W.K.2    Farrell, F.3
  • 30
    • 0032753235 scopus 로고    scopus 로고
    • Erythropoietin in the cerebrospinal fluid of neonates who sustained CNS injury
    • Juul SE, Stallings SA, Christensen RD. Erythropoietin in the cerebrospinal fluid of neonates who sustained CNS injury. Pediatr Res. 1999;46(5):543-547
    • (1999) Pediatr Res , vol.46 , Issue.5 , pp. 543-547
    • Juul, S.E.1    Stallings, S.A.2    Christensen, R.D.3
  • 31
    • 17744377429 scopus 로고    scopus 로고
    • Erythropoietin levels in serum and cerebrospinal fluid of neonates with hypoxic-ischemic encephalopathy
    • Chen N, Mao J, Du Y. Erythropoietin levels in serum and cerebrospinal fluid of neonates with hypoxic-ischemic encephalopathy. Chin J Contemp Pediatr. 2005;7(2):107-111
    • (2005) Chin J Contemp Pediatr , vol.7 , Issue.2 , pp. 107-111
    • Chen, N.1    Mao, J.2    Du, Y.3
  • 32
    • 17144400836 scopus 로고    scopus 로고
    • Clinical pharmacokinetics of lyophilized recombinant human erythropoietin-α following single-dose subcutaneous administration in premature newborns
    • Melo AM, Costa MT, Porta V, Vaz FA. Clinical pharmacokinetics of lyophilized recombinant human erythropoietin-α following single-dose subcutaneous administration in premature newborns. J Matern Fetal Neonatal Med. 2005;17(1):55-58
    • (2005) J Matern Fetal Neonatal Med , vol.17 , Issue.1 , pp. 55-58
    • Melo, A.M.1    Costa, M.T.2    Porta, V.3    Vaz, F.A.4
  • 33
    • 0842329753 scopus 로고    scopus 로고
    • Erythropoietin: A candidate compound for neuroprotection in schizophrenia
    • Ehrenreich H, Degner D, Meller J, et al. Erythropoietin: a candidate compound for neuroprotection in schizophrenia. Mol Psychiatry. 2004;9(1):42-54
    • (2004) Mol Psychiatry , vol.9 , Issue.1 , pp. 42-54
    • Ehrenreich, H.1    Degner, D.2    Meller, J.3
  • 34
    • 0034912641 scopus 로고    scopus 로고
    • Changes in erythropoietin pharmacokinetics following busulfan-induced bone marrow ablation in sheep: Evidence for bone marrow as a major erythropoietin elimination pathway
    • Chapel S, Veng-Pedersen P, Hohl RJ, Schmidt RL, McGuire EM, Widness JA. Changes in erythropoietin pharmacokinetics following busulfan-induced bone marrow ablation in sheep: evidence for bone marrow as a major erythropoietin elimination pathway. J Pharmacol Exp Ther. 2001;298(2): 820-824
    • (2001) J Pharmacol Exp Ther , vol.298 , Issue.2 , pp. 820-824
    • Chapel, S.1    Veng-Pedersen, P.2    Hohl, R.J.3    Schmidt, R.L.4    McGuire, E.M.5    Widness, J.A.6
  • 35
    • 34249048850 scopus 로고    scopus 로고
    • Pharmacokinetics of high-dose recombinant erythropoietin in plasma and brain of neonatal rats
    • Statler PA, McPherson RJ, Bauer LA, Kellert BA, Juul SE. Pharmacokinetics of high-dose recombinant erythropoietin in plasma and brain of neonatal rats. Pediatr Res. 2007;61(6):671- 675
    • (2007) Pediatr Res , vol.61 , Issue.6 , pp. 671-675
    • Statler, P.A.1    McPherson, R.J.2    Bauer, L.A.3    Kellert, B.A.4    Juul, S.E.5
  • 36
    • 0035957426 scopus 로고    scopus 로고
    • Erythropoietin prevents neuronal apoptosis after cerebral ischemia and metabolic stress
    • Sirén AL, Fratelli M, Brines M, et al. Erythropoietin prevents neuronal apoptosis after cerebral ischemia and metabolic stress. Proc Natl Acad Sci U S A. 2001;98(7):4044-4049
    • (2001) Proc Natl Acad Sci U S A , vol.98 , Issue.7 , pp. 4044-4049
    • Sirén, A.L.1    Fratelli, M.2    Brines, M.3
  • 37
    • 34548295610 scopus 로고    scopus 로고
    • Erythropoietin enhances long-term neuroprotection and neurogenesis in neonatal stroke
    • Gonzalez FF, McQuillen P, Mu D, et al. Erythropoietin enhances long-term neuroprotection and neurogenesis in neonatal stroke. Dev Neurosci. 2007;29(4 -5):321-330
    • (2007) Dev Neurosci , vol.29 , Issue.4 -5 , pp. 321-330
    • Gonzalez, F.F.1    McQuillen, P.2    Mu, D.3
  • 38
    • 0141784841 scopus 로고    scopus 로고
    • Erythropoietin selectively attenuates cytokine production and inflammation in cerebral ischemia by targeting neuronal apoptosis
    • Villa P, Bigini P, Mennini T, et al. Erythropoietin selectively attenuates cytokine production and inflammation in cerebral ischemia by targeting neuronal apoptosis. J Exp Med. 2003;198(6): 971-975
    • (2003) J Exp Med , vol.198 , Issue.6 , pp. 971-975
    • Villa, P.1    Bigini, P.2    Mennini, T.3
  • 39
    • 13544277142 scopus 로고    scopus 로고
    • The influence of age on apoptotic and other mechanisms of cell death after cerebral hypoxia-ischemia
    • Zhu C, Wang X, Xu F, et al. The influence of age on apoptotic and other mechanisms of cell death after cerebral hypoxia-ischemia. Cell Death Differ. 2005;12(2):162-176
    • (2005) Cell Death Differ , vol.12 , Issue.2 , pp. 162-176
    • Zhu, C.1    Wang, X.2    Xu, F.3
  • 40
    • 7444267966 scopus 로고    scopus 로고
    • Neonatal brain injury
    • Ferriero DM. Neonatal brain injury. N Engl J Med. 2004;351(19):1985-1995
    • (2004) N Engl J Med , vol.351 , Issue.19 , pp. 1985-1995
    • Ferriero, D.M.1
  • 41
    • 0030727371 scopus 로고    scopus 로고
    • Apoptosis in the brains of infants suffering intrauterine cerebral injury
    • Edwards AD, Yue X, Cox P, et al. Apoptosis in the brains of infants suffering intrauterine cerebral injury. Pediatr Res. 1997;42(5):684-689
    • (1997) Pediatr Res , vol.42 , Issue.5 , pp. 684-689
    • Edwards, A.D.1    Yue, X.2    Cox, P.3
  • 42
    • 33947406873 scopus 로고    scopus 로고
    • Apoptosis-inducing factor is a major contributor to neuronal loss induced by neonatal cerebral hypoxia-ischemia
    • Zhu C, Wang X, Huang Z, et al. Apoptosis-inducing factor is a major contributor to neuronal loss induced by neonatal cerebral hypoxia-ischemia. Cell Death Differ. 2007;14(4):775-784
    • (2007) Cell Death Differ , vol.14 , Issue.4 , pp. 775-784
    • Zhu, C.1    Wang, X.2    Huang, Z.3
  • 43
    • 1442329310 scopus 로고    scopus 로고
    • Irradiation attenuates neurogenesis and exacerbates ischemiainduced deficits
    • Raber J, Fan Y, Matsumori Y, et al. Irradiation attenuates neurogenesis and exacerbates ischemiainduced deficits. Ann Neurol. 2004;55(3):381-389
    • (2004) Ann Neurol , vol.55 , Issue.3 , pp. 381-389
    • Raber, J.1    Fan, Y.2    Matsumori, Y.3
  • 44
    • 55749088804 scopus 로고    scopus 로고
    • Voluntary running rescues adult hippocampal neurogenesis after irradiation of the young mouse brain
    • Naylor AS, Bull C, Nilsson MK, et al. Voluntary running rescues adult hippocampal neurogenesis after irradiation of the young mouse brain. Proc Natl Acad Sci U S A. 2008;105(38):14632-14637
    • (2008) Proc Natl Acad Sci U S A , vol.105 , Issue.38 , pp. 14632-14637
    • Naylor, A.S.1    Bull, C.2    Nilsson, M.K.3
  • 45
    • 49849104424 scopus 로고    scopus 로고
    • A phase I/II trial of high-dose erythropoietin in extremely low birth weight infants: Pharmacokinetics and safety
    • Juul SE, McPherson RJ, Bauer LA, Ledbetter KJ, Gleason CA, Mayock DE. A phase I/II trial of high-dose erythropoietin in extremely low birth weight infants: pharmacokinetics and safety. Pediatrics. 2008;122(2):383-391
    • (2008) Pediatrics , vol.122 , Issue.2 , pp. 383-391
    • Juul, S.E.1    McPherson, R.J.2    Bauer, L.A.3    Ledbetter, K.J.4    Gleason, C.A.5    Mayock, D.E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.