Notch regulation of hematopoiesis, endothelial precursor cells, and blood vessel formation: Orchestrating the vasculature

Stem Cells International

Volumn , Issue , 2012, Pages

  Caolo, Vincenza ^a   Molin, Daniel G M ^a   Post, Mark J ^a  

^a MAASTRICHT UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

JAGGED1; NOTCH RECEPTOR; NOTCH1 RECEPTOR; NOTCH2 RECEPTOR; NOTCH4 RECEPTOR;

ANGIOGENESIS; CELL ACTIVITY; CELL DIFFERENTIATION; CELL POPULATION; CELL RENEWAL; ENDOTHELIAL PROGENITOR CELL; ENZYME REGULATION; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; HUMAN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVIEW; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE;

EID: 84858252962     PISSN: None     EISSN: 16879678     Source Type: Journal    
DOI: 10.1155/2012/805602     Document Type: Review

References (84)

1. Conway E. M., Collen D., Carmeliet P., Molecular mechanisms of blood vessel growth Cardiovascular Research 2001 49 3 507 521 (Pubitemid 32146414)
2. Jain R. K., Molecular regulation of vessel maturation Nature Medicine 2003 9 6 685 693 (Pubitemid 36749217)
3. Djonov V., Baum O., Burri P. H., Vascular remodeling by intussusceptive angiogenesis Cell and Tissue Research 2003 314 1 107 117 (Pubitemid 37409917)
4. Burri P. H., Djonov V., Intussusceptive angiogenesisthe alternative to capillary sprouting Molecular Aspects of Medicine 2002 23 6 S1 S27
5. Weinmaster G., Notch signal transduction: a real Rip and more Current Opinion in Genetics and Development 2000 10 4 363 369 (Pubitemid 30450038)
6. Hurlbut G. D., Kankel M. W., Lake R. J., Artavanis-Tsakonas S., Crossing paths with Notch in the hyper-network Current Opinion in Cell Biology 2007 19 2 166 175 (Pubitemid 46386408)
7. Bray S. J., Notch signalling: a simple pathway becomes complex Nature Reviews Molecular Cell Biology 2006 7 9 678 689 (Pubitemid 44268213)
8. Iso T., Kedes L., Hamamori Y., HES and HERP families: multiple effectors of the Notch signaling pathway Journal of Cellular Physiology 2003 194 3 237 255 (Pubitemid 36176887)
9. Lai E. C., Keeping a good pathway down: transcriptional repression of Notch pathway target genes by CSL proteins EMBO Reports 2002 3 9 840 845 (Pubitemid 35154108)
10. Fischer A., Gessler M., Hey genes in cardiovascular development Trends in Cardiovascular Medicine 2003 13 6 221 226 (Pubitemid 36960168)
11. Ehebauer M., Hayward P., Martinez-Arias A., Notch signaling pathway Science's STKE 2006 2006 364 cm7
12. Krebs L. T., Xue Y., Norton C. R., Shutter J. R., Maguire M., Sundberg J. P., Gallahan D., Closson V., Kitajewski J., Callahan R., Smith G. H., Stark K. L., Gridley T., Notch signaling is essential for vascular morphogenesis in mice Genes and Development 2000 14 11 1343 1352 (Pubitemid 30397078)
13. Xue Y., Gao X., Lindsell C. E., Norton C. R., Chang B., Hicks C., Gendron-Maguire M., Rand E. B., Weinmaster G., Gridley T., Embryonic lethality and vascular defects in mice lacking the Notch ligand Jagged1 Human Molecular Genetics 1999 8 5 723 730 (Pubitemid 29189039)
14. Huppert S. S., Le A., Schroeter E. H., Mumm J. S., Saxena M. T., Milner L. A., Kopan R., Embryonic lethality in mice homozygous for a processing-deficient allele of Notch1 Nature 2000 405 6789 966 970 (Pubitemid 30435055)
15. De Angelis M. H., McIntyre J., Gossler A., Maintenance of somite borders in mice requires the Delta homologue Dll1 Nature 1997 386 6626 717 721 (Pubitemid 27193492)
16. McCright B., Shen L., Lozier J., Lan Y., Maguire M., Herzlinger D., Weinmaster G., Jiang R., Gridley T., Defects in development of the kidney, heart and eye vasculature in mice homozygous for a hypomorphic Notch2 mutation Development 2001 128 4 491 502 (Pubitemid 32229592)
17. Suchting S., Freitas C., Le Noble F., Benedito R., Bréant C., Duarte A., Eichmann A., The Notch ligand Delta-like 4 negatively regulates endothelial tip cell formation and vessel branching Proceedings of the National Academy of Sciences of the United States of America 2007 104 9 3225 3230 (Pubitemid 46364141)
18. Krebs L. T., Shutter J. R., Tanigaki K., Honjo T., Stark K. L., Gridley T., Haploinsufficient lethality and formation of arteriovenous malformations in Notch pathway mutants Genes and Development 2004 18 20 2469 2473 (Pubitemid 39362888)
19. Gale N. W., Dominguez M. G., Noguera I., Pan L., Hughes V., Valenzuela D. M., Murphy A. J., Adams N. C., Lin H. C., Holash J., Thurston G., Yancopoulos G. D., Haploinsufficiency of delta-like 4 ligand results in embryonic lethality due to major defects in arterial and vascular development Proceedings of the National Academy of Sciences of the United States of America 2004 101 45 15949 15954 (Pubitemid 39507907)
20. Warthen D. M., Moore E. C., Kamath B. M., Morrissette J. J. D., Sanchez P., Piccoli D. A., Krantz I. D., Spinner N. B., Jagged1 (JAG1) mutations in Alagille syndrome: increasing the mutation detection rate Human Mutation 2006 27 5 436 443 (Pubitemid 43673330)
21. Kalaria R. N., Viitanen M., Kalimo H., Dichgans M., Tabira T., The pathogenesis of CADASIL: an update Journal of the Neurological Sciences 2004 226 1-2 35 39 (Pubitemid 39505402)
22. Joutel A., Corpechot C., Ducros A., Vahedi K., Chabriat H., Mouton P., Alamowitch S., Domenga V., Cecillion M., Marechal E., Maciazek J., Vayssiere C., Cruaud C., Cabanis E. A., Ruchoux M. M., Weissanbach J., Bach J. F., Bousser M. G., Tournier-Lasserve E., Notch3 mutations in CADASIL, a hereditary adult-onset condition causing stroke and dementia Nature 1996 383 6602 707 710 (Pubitemid 26360644)
23. Godin I., Cumano A., The hare and the tortoise: an embryonic haematopoietic race Nature Reviews Immunology 2002 2 8 593 604 (Pubitemid 37328734)
24. Kumano K., Chiba S., Kunisato A., Sata M., Saito T., Nakagami-Yamaguchi E., Yamaguchi T., Masuda S., Shimizu K., Takahashi T., Ogawa S., Hamada Y., Hirai H., Notch1 but not Notch2 is essential for generating hematopoietic stem cells from endothelial cells Immunity 2003 18 5 699 711 (Pubitemid 36588586)
25. Robert-Moreno A., Espinosa L., de la Pompa J. L., Bigas A., RBPj -dependent Notch function regulates Gata2 and is essential for the formation of intra-embryonic hematopoietic cells Development 2005 132 5 1117 1126 (Pubitemid 40484944)
26. Kumano K., Chiba S., Shimizu K., Yamagata T., Hosoya N., Saito T., Takahashi T., Hamada Y., Hirai H., Notch1 inhibits differentiation of hematopoietic cells by sustaining GATA-2 expression Blood 2001 98 12 3283 3289
27. Robert-Moreno A., Guiu J., Ruiz-Herguido C., Lpez M. E., Inglés-Esteve J., Riera L., Tipping A., Enver T., Dzierzak E., Gridley T., Espinosa L., Bigas A., Impaired embryonic haematopoiesis yet normal arterial development in the absence of the Notch ligand Jagged1 EMBO Journal 2008 27 13 1886 1895 (Pubitemid 351960210)
28. Duncan A. W., Rattis F. M., DiMascio L. N., Congdon K. L., Pazianos G., Zhao C., Yoon K., Cook J. M., Willert K., Gaiano N., Reya T., Integration of Notch and Wnt signaling in hematopoietic stem cell maintenance Nature Immunology 2005 6 3 314 322 (Pubitemid 41724769)
29. Radtke F., Wilson A., Stark G., Bauer M., Van Meerwijk J., MacDonald H. R., Aguet M., Deficient T cell fate specification in mice with an induced inactivation of Notch1 Immunity 1999 10 5 547 558 (Pubitemid 29262657)
30. Mancini S. J. C., Mantei N., Dumortier A., Suter U., MacDonald H. R., Radtke F., Jagged1-dependent Notch signaling is dispensable for hematopoietic stem cell self-renewal and differentiation Blood 2005 105 6 2340 2342 (Pubitemid 40387028)
31. Maillard I., Koch U., Dumortier A., Shestova O., Xu L., Sai H., Pross S. E., Aster J. C., Bhandoola A., Radtke F., Pear W. S., Canonical Notch signaling is dispensable for the maintenance of adult hematopoietic stem cells Cell Stem Cell 2008 2 4 356 366 (Pubitemid 351455243)
32. Varnum-Finney B., Xu L., Brashem-Stein C., Nourigat C., Flowers D., Bakkour S., Pear W. S., Bernstein I. D., Pluripotent, cytokine-dependent, hematopoietic stem cells are immortalized by constitutive Notch1 signaling Nature Medicine 2000 6 11 1278 1281
33. Stier S., Cheng T., Dombkowski D., Carlesso N., Scadden D. T., Notch1 activation increases hematopoietic stem cell self-renewal in vivo and favors lymphoid over myeloid lineage outcome Blood 2002 99 7 2369 2378 (Pubitemid 34525422)
34. Vercauteren S. M., Sutherland H. J., Constitutively active Notch4 promotes early human hematopoietic progenitor cell maintenance while inhibiting differentiation and causes lymphoid abnormalities in vivo Blood 2004 104 8 2315 2322 (Pubitemid 39331828)
35. Karanu F. N., Murdoch B., Gallacher L., Wu D. M., Koremoto M., Sakano S., Bhatia M., The Notch ligand Jagged-1 represents a novel growth factor of human hematopoietic stem cells Journal of Experimental Medicine 2000 192 9 1365 1372
36. Varnum-Finney B., Brashem-Stein C., Bernstein I. D., Combined effects of Notch signaling and cytokines induce a multiple log increase in precursors with lymphoid and myeloid reconstituting ability Blood 2003 101 5 1784 1789 (Pubitemid 36237574)
37. Kunisato A., Chiba S., Nakagami-Yamaguchi E., Kumano K., Saito T., Masuda S., Yamaguchi T., Osawa M., Kageyama R., Nakauchi H., Nishikawa M., Hirai H., HES-1 preserves purified hematopoietic stem cells ex vivo and accumulates side population cells in vivo Blood 2003 101 5 1777 1783 (Pubitemid 36237573)
38. Asahara T., Murohara T., Sullivan A., Silver M., Van Der Zee R., Li T., Witzenbichler B., Schatteman G., Isner J. M., Isolation of putative progenitor endothelial cells for angiogenesis Science 1997 275 5302 964 967 (Pubitemid 27087709)
39. Yin T., Li L., The stem cell niches in bone Journal of Clinical Investigation 2006 116 5 1195 1201
40. Huang X., Cho S., Spangrude G. J., Hematopoietic stem cells: generation and self-renewal Cell Death and Differentiation 2007 14 11 1851 1859 (Pubitemid 350011661)
41. Calvi L. M., Osteoblastic activation in the hematopoietic stem cell niche Annals of the New York Academy of Sciences 2006 1068 1 477 488 (Pubitemid 43824176)
42. Weber J. M., Forsythe S. R., Christianson C. A., Frisch B. J., Gigliotti B. J., Jordan C. T., Milner L. A., Guzman M. L., Calvi L. M., Parathyroid hormone stimulates expression of the Notch ligand Jagged1 in osteoblastic cells Bone 2006 39 3 485 493 (Pubitemid 44149274)
43. Chitteti B. R., Cheng Y. H., Poteat B., Rodriguez-Rodriguez S., Goebel W. S., Carlesso N., Kacena M. A., Srour E. F., Impact of interactions of cellular components of the bone marrow microenvironment on hematopoietic stem and progenitor cell function Blood 2010 115 16 3239 3248
44. Kwon S. M., Eguchi M., Wada M., Iwami Y., Hozumi K., Iwaguro H., Masuda H., Kawamoto A., Asahara T., Specific jagged-1 signal from bone marrow microenvironment is required for endothelial progenitor cell development for neovascularization Circulation 2008 118 2 157 165
45. Siekmann A. F., Covassin L., Lawson N. D., Modulation of VEGF signalling output by the Notch pathway BioEssays 2008 30 4 303 313 (Pubitemid 351482328)
46. Jakobsson L., Bentley K., Gerhardt H., VEGFRs and Notch: a dynamic collaboration in vascular patterning Biochemical Society Transactions 2009 37 6 1233 1236
47. Gerhardt H., Golding M., Fruttiger M., Ruhrberg C., Lundkvist A., Abramsson A., Jeltsch M., Mitchell C., Alitalo K., Shima D., Betsholtz C., VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia Journal of Cell Biology 2003 161 6 1163 1177 (Pubitemid 36870177)
48. Gerhardt H., Ruhrberg C., Abramsson A., Fujisawa H., Shima D., Betsholtz C., Neuropilin-1 is required for endothelial tip cell guidance in the developing central nervous system Developmental Dynamics 2004 231 3 503 509 (Pubitemid 39410884)
49. Hellstrm M., Phng L. K., Hofmann J. J., Wallgard E., Coultas L., Lindblom P., Alva J., Nilsson A. K., Karlsson L., Gaiano N., Yoon K., Rossant J., Iruela-Arispe M. L., Kalén M., Gerhardt H., Betsholtz C., Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis Nature 2007 445 7129 776 780 (Pubitemid 46279716)
50. Lobov I. B., Renard R. A., Papadopoulos N., Gale N. W., Thurston G., Yancopoulos G. D., Wiegand S. J., Delta-like ligand 4 (DII4) is induced by VEGF as a negative regulator of angiogenic sprouting Proceedings of the National Academy of Sciences of the United States of America 2007 104 9 3219 3224 (Pubitemid 46364140)
51. Ridgway J., Zhang G., Wu Y., Stawicki S., Liang W. C., Chanthery Y., Kowalski J., Watts R. J., Callahan C., Kasman I., Singh M., Chien M., Tan C., Hongo J. A. S., De Sauvage F., Plowman G., Yan M., Inhibition of Dll4 signalling inhibits tumour growth by deregulating angiogenesis Nature 2006 444 7122 1083 1087 (Pubitemid 46018529)
52. Leslie J. D., Ariza-McNaughton L., Bermange A. L., McAdow R., Johnson S. L., Lewis J., Endothelial signalling by the Notch ligand Delta-like 4 restricts angiogenesis Development 2007 134 5 839 844 (Pubitemid 46795675)
53. Siekmann A. F., Lawson N. D., Notch signalling limits angiogenic cell behaviour in developing zebrafish arteries Nature 2007 445 7129 781 784 (Pubitemid 46279717)
54. Noguera-Troise I., Daly C., Papadopoulos N. J., Coetzee S., Boland P., Gale N. W., Chieh Lin H., Yancopoulos G. D., Thurston G., Blockade of Dll4 inhibits tumour growth by promoting non-productive angiogenesis Nature 2006 444 7122 1032 1037 (Pubitemid 46018516)
55. Scehnet J. S., Jiang W., Kumar S. R., Krasnoperov V., Trindade A., Benedito R., Djokovic D., Borges C., Ley E. J., Duarte A., Gill P. S., Inhibition of Dll4-mediated signaling induces proliferation of immature vessels and results in poor tissue perfusion Blood 2007 109 11 4753 4760 (Pubitemid 46827768)
56. Caolo V., Van Den Akker N. M. S., Verbruggen S., Donners M. M. P. C., Swennen G., Schulten H., Waltenberger J., Post M. J., Molin D. G. M., Feed-forward signaling by membrane-bound ligand receptor circuit: the case of notch delta-like 4 ligand in endothelial cells Journal of Biological Chemistry 2010 285 52 40681 40689
57. Delwig A., Rand M. D., Kuz and TACE can activate Notch independent of ligand Cellular and Molecular Life Sciences 2008 65 14 2232 2243
58. Hofmann J. J., Luisa Iruela-Arispe M., Notch expression patterns in the retina: an eye on receptor-ligand distribution during angiogenesis Gene Expression Patterns 2007 7 4 461 470 (Pubitemid 46177950)
59. Bentley K., Gerhardt H., Bates P. A., Agent-based simulation of notch-mediated tip cell selection in angiogenic sprout initialisation Journal of Theoretical Biology 2008 250 1 25 36 (Pubitemid 350160711)
60. Bentley K., Mariggi G., Gerhardt H., Bates P. A., Tipping the balance: robustness of tip cell selection, migration and fusion in angiogenesis PLoS Computational Biology 2009 5 10
61. Jakobsson L., Franco C. A., Bentley K., Collins R. T., Ponsioen B., Aspalter I. M., Rosewell I., Busse M., Thurston G., Medvinsky A., Schulte-Merker S., Gerhardt H., Endothelial cells dynamically compete for the tip cell position during angiogenic sprouting Nature Cell Biology 2010 12 10 943 953
62. Williams C. K., Li J. L., Murga M., Harris A. L., Tosato G., Up-regulation of the Notch ligand Delta-like 4 inhibits VEGF-induced endothelial cell function Blood 2006 107 3 931 939 (Pubitemid 43156289)
63. Tammela T., Zarkada G., Nurmi H., Jakobsson L., Heinolainen K., Tvorogov D., Zheng W., Franco C. A., Murtomki A., Aranda E., Miura N., Yl-Herttuala S., Fruttiger M., Mkinen T., Eichmann A., Pollard J. W., Gerhardt H., Alitalo K., VEGFR-3 controls tip to stalk conversion at vessel fusion sites by reinforcing Notch signalling Nature Cell Biology 2011 13 10 1202 1213
64. Lawson N. D., Vogel A. M., Weinstein B. M., Sonic hedgehog and vascular endothelial growth factor act upstream of the Notch pathway during arterial endothelial differentiation Developmental Cell 2002 3 1 127 136 (Pubitemid 34778401)
65. Lawson N. D., Scheer N., Pham V. N., Kim C. H., Chitnis A. B., Campos-Ortega J. A., Weinstein B. M., Notch signaling is required for arterial-venous differentiation during embryonic vascular development Development 2001 128 19 3675 3683 (Pubitemid 32998917)
66. Duarte A., Hirashima M., Benedito R., Trindade A., Diniz P., Bekman E., Costa L., Henrique D., Rossant J., Dosage-sensitive requirement for mouse Dll4 in artery development Genes and Development 2004 18 20 2474 2478 (Pubitemid 39362889)
67. Fischer A., Schumacher N., Maier M., Sendtner M., Gessler M., The Notch target genes Hey1 and Hey2 are required for embryonic vascular development Genes and Development 2004 18 8 901 911 (Pubitemid 38529659)
68. Kokubo H., Miyagawa-Tomita S., Nakazawa M., Saga Y., Johnson R. L., Mouse hesr1 and hesr2 genes are redundantly required to mediate Notch signaling in the developing cardiovascular system Developmental Biology 2005 278 2 301 309 (Pubitemid 40175030)
69. Van Den Akker N. M. S., Caolo V., Wisse L. J., Peters P. P. W. M., Poelmann R. E., Carmeliet P., Molin D. G. M., Gittenberger-De Groot A. C., Developmental coronary maturation is disturbed by aberrant cardiac vascular endothelial growth factor expression and Notch signalling Cardiovascular Research 2008 78 2 366 375 (Pubitemid 351556095)
70. Liu Z. J., Shirakawa T., Li Y., Soma A., Oka M., Dotto G. P., Fairman R. M., Velazquez O. C., Herlyn M., Regulation of Notch1 and Dll4 by vascular endothelial growth factor in arterial endothelial cells: implications for modulating arteriogenesis and angiogenesis Molecular and Cellular Biology 2003 23 1 14 25 (Pubitemid 36008497)
71. Lanner F., Sohl M., Farnebo F., Functional arterial and venous fate is determined by graded VEGF signaling and notch status during embryonic stem cell differentiation Arteriosclerosis, Thrombosis, and Vascular Biology 2007 27 3 487 493
72. Zhang G., Zhou J., Fan Q., Zheng Z., Zhang F., Liu X., Hu S., Arterial-venous endothelial cell fate is related to vascular endothelial growth factor and Notch status during human bone mesenchymal stem cell differentiation FEBS Letters 2008 582 19 2957 2964
73. You L. R., Lin F. J., Lee C. T., DeMayo F. J., Tsai M. J., Tsai S. Y., Suppression of Notch signalling by the COUP-TFII transcription factor regulates vein identity Nature 2005 435 7038 98 104 (Pubitemid 40655915)
74. Iso T., Maeno T., Oike Y., Yamazaki M., Doi H., Arai M., Kurabayashi M., Dll4-selective Notch signaling induces ephrinB2 gene expression in endothelial cells Biochemical and Biophysical Research Communications 2006 341 3 708 714 (Pubitemid 43177547)
75. Carlson T. R., Yan Y., Wu X., Lam M. T., Tang G. L., Beverly L. J., Messina L. M., Capobianco A. J., Werb Z., Wang R., Endothelial expression of constitutively active Notch4 elicits reversible arteriovenous malformations in adult mice Proceedings of the National Academy of Sciences of the United States of America 2005 102 28 9884 9889 (Pubitemid 40993662)
76. Majesky M. W., Developmental basis of vascular smooth muscle diversity Arteriosclerosis, Thrombosis, and Vascular Biology 2007 27 6 1248 1258 (Pubitemid 46809412)
77. Domenga V., Fardoux P., Lacombe P., Monet M., Maciazek J., Krebs L. T., Klonjkowski B., Berrou E., Mericskay M., Li Z., Tournier-Lasserve E., Gridley T., Joutel A., Notch3 is required for arterial identity and maturation of vascular smooth muscle cells Genes and Development 2004 18 22 2730 2735 (Pubitemid 39507766)
78. Moessler H., Mericskay M., Li Z., Nagl S., Paulin D., Small J. V., The SM 22 promoter directs tissue-specific expression in arterial but not in venous or visceral smooth muscle cells in transgenic mice Development 1996 122 8 2415 2425 (Pubitemid 26265601)
79. Doi H., Iso T., Sato H., Yamazaki M., Matsui H., Tanaka T., Manabe I., Arai M., Nagai R., Kurabayashi M., Jagged1-selective notch signaling induces smooth muscle differentiation via a RBP-J -dependent pathway Journal of Biological Chemistry 2006 281 39 28555 28564 (Pubitemid 44506998)
80. Liu H., Kennard S., Lilly B., NOTCH3 expression is induced in mural cells through an autoregulatory loop that requires Endothelial-expressed JAGGED1 Circulation Research 2009 104 4 466 475
81. High F. A., Lu M. M., Pear W. S., Loomes K. M., Kaestner K. H., Epstein J. A., Endothelial expression of the Notch ligand Jagged1 is required for vascular smooth muscle development Proceedings of the National Academy of Sciences of the United States of America 2008 105 6 1955 1959 (Pubitemid 351439446)
82. Doi H., Iso T., Yamazaki M., Akiyama H., Kanai H., Sato H., Kawai-Kowase K., Tanaka T., Maeno T., Okamoto E. I., Arai M., Kedes L., Kurabayashi M., HERP1 inhibits myocardin-induced vascular smooth muscle cell differentiation by interfering with SRF binding to CArG box Arteriosclerosis, Thrombosis, and Vascular Biology 2005 25 11 2328 2334 (Pubitemid 41552650)
83. Tang Y., Urs S., Liaw L., Hairy-related transcription factors inhibit notch-induced smooth muscle -actin expression by interfering with notch intracellular domain/CBF-1 complex interaction with the CBF-1-binding site Circulation Research 2008 102 6 661 668 (Pubitemid 351457858)
84. Proweller A., Pear W. S., Parmacek M. S., Notch signaling represses myocardin-induced smooth muscle cell differentiation Journal of Biological Chemistry 2005 280 10 8994 9004 (Pubitemid 40409591)