Dll4-selective Notch signaling induces ephrinB2 gene expression in endothelial cells

Biochemical and Biophysical Research Communications

Volumn 341, Issue 3, 2006, Pages 708-714

  Iso, Tatsuya ^a   Maeno, Toshitaka ^a   Oike, Yuichi ^b   Yamazaki, Miki ^a   Doi, Hiroshi ^a   Arai, Masashi ^a   Kurabayashi, Masahiko ^a  

^a GUNMA UNIVERSITY   (Japan)

^b KEIO UNIVERSITY   (Japan)

Author keywords

ALK1; Arterial venous differentiation; Dll4; Endothelial cells; EphB4; EphrinB2; HERP; Jagged1; Notch signaling; TGF

Indexed keywords

CONNEXIN 40; EPHRIN B2; MEMBRANE PROTEIN; NOTCH RECEPTOR; TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1;

ARTICLE; CONTROLLED STUDY; ENDOTHELIUM CELL; GENE EXPRESSION; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN INTERACTION;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BIOLOGICAL MARKERS; CALCIUM-BINDING PROTEINS; CELLS, CULTURED; ENDOTHELIAL CELLS; EPHRIN-B2; GENE EXPRESSION REGULATION; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LIGANDS; MEMBRANE PROTEINS; MICE; RECEPTORS, NOTCH; REPRESSOR PROTEINS; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA;

EID: 31744441971     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2006.01.020     Document Type: Article

References (45)

1. H.U. Wang, Z.F. Chen, and D.J. Anderson Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor Eph-B4 Cell 93 1998 741 753
2. S.S. Gerety, H.U. Wang, Z.F. Chen, and D.J. Anderson Symmetrical mutant phenotypes of the receptor EphB4 and its specific transmembrane ligand ephrin-B2 in cardiovascular development Mol. Cell 4 1999 403 414
3. J. Torres-Vazquez, M. Kamei, and B.M. Weinstein Molecular distinction between arteries and veins Cell Tissue Res. 314 2003 43 59
4. T. Iso, Y. Hamamori, and L. Kedes Notch signaling in vascular development Arterioscler. Thromb. Vasc. Biol. 23 2003 543 553
5. C.J. Shawber, and J. Kitajewski Notch function in the vasculature: insights from zebrafish, mouse and man Bioessays 26 2004 225 234
6. F. Lebrin, M. Deckers, P. Bertolino, and P. Ten Dijke TGF-beta receptor function in the endothelium Cardiovasc. Res. 65 2005 599 608
7. S. Artavanis-Tsakonas, M.D. Rand, and R.J. Lake Notch signaling: cell fate control and signal integration in development Science 284 1999 770 776
8. N. Villa, L. Walker, C.E. Lindsell, J. Gasson, M.L. Iruela-Arispe, and G. Weinmaster Vascular expression of Notch pathway receptors and ligands is restricted to arterial vessels Mech. Dev. 108 2001 161 164
9. N.D. Lawson, N. Scheer, V.N. Pham, C.H. Kim, A.B. Chitnis, J.A. Campos-Ortega, and B.M. Weinstein Notch signaling is required for arterial-venous differentiation during embryonic vascular development Development 128 2001 3675 3683
10. T.P. Zhong, S. Childs, J.P. Leu, and M.C. Fishman Gridlock signalling pathway fashions the first embryonic artery Nature 414 2001 216 220
11. A. Duarte, M. Hirashima, R. Benedito, A. Trindade, P. Diniz, E. Bekman, L. Costa, D. Henrique, and J. Rossant Dosage-sensitive requirement for mouse Dll4 in artery development Genes Dev. 18 2004 2474 2478
12. L.T. Krebs, J.R. Shutter, K. Tanigaki, T. Honjo, K.L. Stark, and T. Gridley Haploinsufficient lethality and formation of arteriovenous malformations in Notch pathway mutants Genes Dev. 18 2004 2469 2473
13. N.W. Gale, M.G. Dominguez, I. Noguera, L. Pan, V. Hughes, D.M. Valenzuela, A.J. Murphy, N.C. Adams, H.C. Lin, J. Holash, G. Thurston, and G.D. Yancopoulos Haploinsufficiency of delta-like 4 ligand results in embryonic lethality due to major defects in arterial and vascular development Proc. Natl. Acad. Sci. USA 101 2004 15949 15954
14. A. Fischer, N. Schumacher, M. Maier, M. Sendtner, and M. Gessler The Notch target genes Hey1 and Hey2 are required for embryonic vascular development Genes Dev. 18 2004 901 911
15. H. Kokubo, S. Miyagawa-Tomita, M. Nakazawa, Y. Saga, and R.L. Johnson Mouse hesr1 and hesr2 genes are redundantly required to mediate Notch signaling in the developing cardiovascular system Dev. Biol. 278 2005 301 309
16. D.W. Johnson, J.N. Berg, M.A. Baldwin, C.J. Gallione, I. Marondel, S.J. Yoon, T.T. Stenzel, M. Speer, M.A. Pericak-Vance, A. Diamond, A.E. Guttmacher, C.E. Jackson, L. Attisano, R. Kucherlapati, M.E. Porteous, and D.A. Marchuk Mutations in the activin receptor-like kinase 1 gene in hereditary haemorrhagic telangiectasia type 2 Nat. Genet. 13 1996 189 195
17. L.D. Urness, L.K. Sorensen, and D.Y. Li Arteriovenous malformations in mice lacking activin receptor-like kinase-1 Nat. Genet. 26 2000 328 331
18. T. Seki, J. Yun, and S.P. Oh Arterial endothelium-specific activin receptor-like kinase 1 expression suggests its role in arterialization and vascular remodeling Circ. Res. 93 2003 682 689
19. C. Dahlqvist, A. Blokzijl, G. Chapman, A. Falk, K. Dannaeus, C.F. Ibanez, and U. Lendahl Functional Notch signaling is required for BMP4-induced inhibition of myogenic differentiation Development 130 2003 6089 6099
20. T. Takizawa, W. Ochiai, K. Nakashima, and T. Taga Enhanced gene activation by Notch and BMP signaling cross-talk Nucleic Acids Res. 31 2003 5723 5731
21. F. Itoh, S. Itoh, M.J. Goumans, G. Valdimarsdottir, T. Iso, G.P. Dotto, Y. Hamamori, L. Kedes, M. Kato, and P. ten Dijke Pt Synergy and antagonism between Notch and BMP receptor signaling pathways in endothelial cells EMBO J. 23 2004 541 551
22. M. Noseda, G. McLean, K. Niessen, L. Chang, I. Pollet, R. Montpetit, R. Shahidi, K. Dorovini-Zis, L. Li, B. Beckstead, R.E. Durand, P.A. Hoodless, and A. Karsan Notch activation results in phenotypic and functional changes consistent with endothelial-to-mesenchymal transformation Circ. Res. 94 2004 910 917
23. L.A. Timmerman, J. Grego-Bessa, A. Raya, E. Bertran, J.M. Perez-Pomares, J. Diez, S. Aranda, S. Palomo, F. McCormick, J.C. Izpisua-Belmonte, and J.L. de la Pompa Notch promotes epithelial-mesenchymal transition transition during cardiac development and oncogenic transformation Genes Dev. 18 2004 99 115
24. J. Zavadil, L. Cermak, N. Soto-Nieves, and E.P. Bottinger Integration of TGF-beta/Smad and Jagged1/Notch signalling in epithelial-to-mesenchymal transition EMBO J. 23 2004 1155 1165
25. T. Iso, V. Sartorelli, G. Chung, T. Shichinohe, L. Kedes, and Y. Hamamori Herp, a new primary target of notch regulated by ligand binding Mol. Cell. Biol. 21 2001 6071 6079
26. T. Ota, M. Fujii, T. Sugizaki, M. Ishii, K. Miyazawa, H. Aburatani, and K. Miyazono Targets of transcriptional regulation by two distinct type I receptors for transforming growth factor-beta in human umbilical vein endothelial cells J. Cell. Physiol. 193 2002 299 318
27. C.E. Lindsell, C.J. Shawber, J. Boulter, and G. Weinmaster Jagged: a mammalian ligand that activates Notch1 Cell 80 1995 909 917
28. K. Niwano, M. Arai, K. Tomaru, T. Uchiyama, Y. Ohyama, and M. Kurabayashi Transcriptional stimulation of the eNOS gene by the stable prostacyclin analogue beraprost is mediated through cAMP-responsive element in vascular endothelial cells: close link between PGI2 signal and NO pathways Circ. Res. 93 2003 523 530
29. J.R. Shutter, S. Scully, W. Fan, W.G. Richards, J. Kitajewski, G.A. Deblandre, C.R. Kintner, and K.L. Stark Dll4, a novel Notch ligand expressed in arterial endothelium Genes Dev. 14 2000 1313 1318
30. T. Shichinohe, B.H. Bochner, K. Mizutani, M. Nishida, S. Hegerich-Gilliam, L. Naldini, and N. Kasahara Development of lentiviral vectors for antiangiogenic gene delivery Cancer Gene Ther. 8 2001 879 889
31. D. Amsen, J.M. Blander, G.R. Lee, K. Tanigaki, T. Honjo, and R.A. Flavell Instruction of distinct CD4 T helper cell fates by different notch ligands on antigen-presenting cells Cell 117 2004 515 526
32. S. Rutz, B. Mordmuller, S. Sakano, and A. Scheffold Notch ligands Delta-like1, Delta-like4 and Jagged1 differentially regulate activation of peripheral T helper cells Eur. J. Immunol. 35 2005 2443 2451
33. K. Shimizu, S. Chiba, K. Kumano, N. Hosoya, T. Takahashi, Y. Kanda, Y. Hamada, Y. Yazaki, and H. Hirai Mouse jagged1 physically interacts with notch2 and other notch receptors. Assessment by quantitative methods J. Biol. Chem. 274 1999 32961 32969
34. K. Shimizu, S. Chiba, T. Saito, K. Kumano, and H. Hirai Physical interaction of Delta1, Jagged1, Jagged2 with Notch1 and Notch3 receptors Biochem. Biophys. Res. Commun. 276 2000 385 389
35. D.J. Moloney, V.M. Panin, S.H. Johnston, J. Chen, L. Shao, R. Wilson, Y. Wang, P. Stanley, K.D. Irvine, R.S. Haltiwanger, and T.F. Vogt Fringe is a glycosyltransferase that modifies Notch Nature 406 2000 369 375
36. K. Bruckner, L. Perez, H. Clausen, and S. Cohen Glycosyltransferase activity of Fringe modulates Notch-Delta interactions Nature 406 2000 411 415
37. T. Okajima, and K.D. Irvine Regulation of notch signaling by o-linked fucose Cell 111 2002 893 904
38. V.M. Panin, V. Papayannopoulos, R. Wilson, and K.D. Irvine Fringe modulates Notch-ligand interactions Nature 387 1997 908 912
39. C. Hicks, S.H. Johnston, G. diSibio, A. Collazo, T.F. Vogt, and G. Weinmaster Fringe differentially modulates Jagged1 and Delta1 signalling through Notch1 and Notch2 Nat. Cell Biol. 2 2000 515 520
40. K. Shimizu, S. Chiba, T. Saito, K. Kumano, T. Takahashi, and H. Hirai Manic fringe and lunatic fringe modify different sites of the Notch2 extracellular region, resulting in different signaling modulation J. Biol. Chem. 276 2001 25753 25758
41. L.T. Yang, J.T. Nichols, C. Yao, J.O. Manilay, E.A. Robey, and G. Weinmaster Fringe glycosyltransferases differentially modulate Notch1 proteolysis induced by Delta1 and Jagged1 Mol. Biol. Cell 16 2005 927 942
42. M. Gessler, K.-P. Knobeloch, A. Helisch, K. Amann, N. Schumacher, E. Rohde, A. Fischer, and C. Leimeister Mouse gridlock: no aortic coarctation or deficiency, but fetal cardiac defects in Hey2 -/- mice Curr. Biol. 12 2002 16011604
43. J. Donova, A. Kordylewska, Y.N. Jan, and M.F. Utset Tetralogy of Fallot and other congenital heart defects in Hey2 mutant mice Curr. Biol. 12 2002 1605 1610
44. Y. Sakata, F. Xiang, Z. Chen, Y. Kiriyama, C.N. Kamei, D.I. Simon, and M.T. Chin Transcription factor CHF1/Hey2 regulates neointimal formation in vivo and vascular smooth muscle proliferation and migration in vitro Arterioscler. Thromb. Vasc. Biol. 24 2004 2069 2074
45. T. Seki, K.H. Hong, J. Yun, S.J. Kim, and S.P. Oh Isolation of a regulatory region of activin receptor-like kinase 1 gene sufficient for arterial endothelium-specific expression Circ. Res. 94 2004 e72 e77