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Volumn 14, Issue 11, 2007, Pages 1851-1859

Hematopoietic stem cells: Generation and self-renewal

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOPOIETIN RECEPTOR; ANGIOTENSIN I; BETA CATENIN; BETA1 INTEGRIN; BONE MORPHOGENETIC PROTEIN; BONE MORPHOGENETIC PROTEIN RECEPTOR 1; CALCIUM ION; CHEMOKINE RECEPTOR CXCR4; CYTOKINE; FRIZZLED PROTEIN; INTEGRIN; JAGGED1; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN; NERVE CELL ADHESION MOLECULE; NOTCH RECEPTOR; NOTCH1 RECEPTOR; PROTEIN BCL 2; PROTEIN P18; PROTEIN P21; SONIC HEDGEHOG PROTEIN; STAT3 PROTEIN; STAT5 PROTEIN; STRESS ACTIVATED PROTEIN KINASE; STROMAL CELL DERIVED FACTOR 1; T CELL FACTOR PROTEIN; TRANSCRIPTION FACTOR ETS; TRANSCRIPTION FACTOR RUNX1; WNT PROTEIN; WNT3A PROTEIN;

EID: 35548932909     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/sj.cdd.4402225     Document Type: Review
Times cited : (89)

References (70)
  • 1
    • 24044484750 scopus 로고    scopus 로고
    • Hematopoiesis in the yolk sac: More than meets the eye
    • McGrath KE, Palis J. Hematopoiesis in the yolk sac: More than meets the eye. Exp Hematol 2005; 33: 1021-1028.
    • (2005) Exp Hematol , vol.33 , pp. 1021-1028
    • McGrath, K.E.1    Palis, J.2
  • 2
    • 0016811829 scopus 로고
    • Role of stem cell migration in initiation of mouse fetal liver haematopolesis
    • Johnson GR, Moore MAS. Role of stem cell migration in initiation of mouse fetal liver haematopolesis. Nature 1975; 258: 726-728.
    • (1975) Nature , vol.258 , pp. 726-728
    • Johnson, G.R.1    Moore, M.A.S.2
  • 3
    • 0032427448 scopus 로고    scopus 로고
    • Hematopoietic induction and respecification of A-P identity by visceral endoderm signaling in the mouse embryo
    • Belaoussoff M, Farrington SM, Baron MH. Hematopoietic induction and respecification of A-P identity by visceral endoderm signaling in the mouse embryo. Devolopment 1998; 125: 5009-5018.
    • (1998) Devolopment , vol.125 , pp. 5009-5018
    • Belaoussoff, M.1    Farrington, S.M.2    Baron, M.H.3
  • 4
    • 2642552297 scopus 로고    scopus 로고
    • Origins of mammalian hematopoiesis: In vivo paradigms and in vitro models
    • Lensch MW, Daley GQ. Origins of mammalian hematopoiesis: in vivo paradigms and in vitro models. Curr Topics Dev Biol 2004; 60: 127-196.
    • (2004) Curr Topics Dev Biol , vol.60 , pp. 127-196
    • Lensch, M.W.1    Daley, G.Q.2
  • 5
    • 3042712917 scopus 로고    scopus 로고
    • Yolk sac-derived primitive erythroblasts enucleate during mammalian embryogenesis
    • Kingsley PD, Malik J, Fantauzzo KA, Palis J. Yolk sac-derived primitive erythroblasts enucleate during mammalian embryogenesis. Blood 2004; 104: 19-25.
    • (2004) Blood , vol.104 , pp. 19-25
    • Kingsley, P.D.1    Malik, J.2    Fantauzzo, K.A.3    Palis, J.4
  • 6
    • 0033405452 scopus 로고
    • Development of erythroid and myeloid progenitors in the yolk sac and embryo proper of the mouse
    • Palis J, Robertson S, Kennedy M, Wall C, Keller G. Development of erythroid and myeloid progenitors in the yolk sac and embryo proper of the mouse. Development 1909; 126: 5073-5084.
    • (1909) Development , vol.126 , pp. 5073-5084
    • Palis, J.1    Robertson, S.2    Kennedy, M.3    Wall, C.4    Keller, G.5
  • 7
    • 0035313155 scopus 로고    scopus 로고
    • Evidence for the presence of murine primitive megakaryocytopoiessis in the early yolk sac
    • Xu MJ, Matsuoka S, Yang FC, Ebihara Y, Manabe A, Tanaka R et al. Evidence for the presence of murine primitive megakaryocytopoiessis in the early yolk sac. Blood 2001; 97: 20167-2022.
    • (2001) Blood , vol.97 , pp. 20167-22022
    • Xu, M.J.1    Matsuoka, S.2    Yang, F.C.3    Ebihara, Y.4    Manabe, A.5    Tanaka, R.6
  • 8
    • 33846907357 scopus 로고    scopus 로고
    • The megakaryocyte lineage originates from hemangioblast precursors and is an integral component both of primitive and of definitive hematopoiesis
    • Tober J, Koniski A, McGrath KE, Vemishetti R, Emerson R, de Mesy-Bentley KK et al. The megakaryocyte lineage originates from hemangioblast precursors and is an integral component both of primitive and of definitive hematopoiesis. Blood 2007; 109: 1433-1441.
    • (2007) Blood , vol.109 , pp. 1433-1441
    • Tober, J.1    Koniski, A.2    McGrath, K.E.3    Vemishetti, R.4    Emerson, R.5    de Mesy-Bentley, K.K.6
  • 9
    • 0014744817 scopus 로고
    • Ontogeny of the haemopoietic system: Yolk sac origin of in vivo and in vitro colony forming cells in the developing mouse embryo
    • Moore MAS, Metcalf D. Ontogeny of the haemopoietic system: Yolk sac origin of in vivo and in vitro colony forming cells in the developing mouse embryo. Br J Haematol 1970; 18: 279-296.
    • (1970) Br J Haematol , vol.18 , pp. 279-296
    • Moore, M.A.S.1    Metcalf, D.2
  • 10
    • 0001776644 scopus 로고
    • Fetal hematopoietic origins of the adult hematolymphoid system
    • Clarkson B ed, Cold Spring Harbor Laboratory Press: Cold Spring Harbor, New York
    • Weissman I, Papaloannou V, Gardner R. Fetal hematopoietic origins of the adult hematolymphoid system. In: Clarkson B (ed). Differentiation of Normal and Neoplastic Hematopoetic Cells. Cold Spring Harbor Laboratory Press: Cold Spring Harbor, New York, 1978 pp 33-47.
    • (1978) Differentiation of Normal and Neoplastic Hematopoetic Cells , pp. 33-47
    • Weissman, I.1    Papaloannou, V.2    Gardner, R.3
  • 11
    • 0026343035 scopus 로고
    • In vitro development of murine T cells from prethymic and preliver embryonic yolk sac hematopoietic stem cells
    • Liu CP, Auerbach R. In vitro development of murine T cells from prethymic and preliver embryonic yolk sac hematopoietic stem cells. Development 1991; 113: 1315-1323.
    • (1991) Development , vol.113 , pp. 1315-1323
    • Liu, C.P.1    Auerbach, R.2
  • 12
    • 0016785660 scopus 로고
    • On the origin of haemopoietic stem cells in the avian embryo: An experimental approach
    • Dieterien-Lièvre F. On the origin of haemopoietic stem cells in the avian embryo: An experimental approach. J Embryol Exp Morphol 1975; 33: 607-619.
    • (1975) J Embryol Exp Morphol , vol.33 , pp. 607-619
    • Dieterien-Lièvre, F.1
  • 13
    • 0028909563 scopus 로고
    • Intraembryonic origin of hepatic hematopoiesis in Xenopus laevis
    • Chen XD, Turpen JB. Intraembryonic origin of hepatic hematopoiesis in Xenopus laevis. J Immunol 1985; 154: 2557-2567.
    • (1985) J Immunol , vol.154 , pp. 2557-2567
    • Chen, X.D.1    Turpen, J.B.2
  • 14
    • 0027178567 scopus 로고
    • An early pre-liver intraembryonic source of CFU-S in the developing mouse
    • Medvinsky AL, Samoylina NL, Muller AM, Dzierzak EA. An early pre-liver intraembryonic source of CFU-S in the developing mouse. Nature 1993; 364: 64-67.
    • (1993) Nature , vol.364 , pp. 64-67
    • Medvinsky, A.L.1    Samoylina, N.L.2    Muller, A.M.3    Dzierzak, E.A.4
  • 15
    • 0027321323 scopus 로고
    • Differentiation and characterization of B-cell precursors detected in the yolk sac and embryo body of embryos beginning at the 10- to 12-somite stage
    • Cumano A, Furlonger C, Paige CJ. Differentiation and characterization of B-cell precursors detected in the yolk sac and embryo body of embryos beginning at the 10- to 12-somite stage. Proc Natl Acad Sci (USA) 1993; 90: 6429-6433.
    • (1993) Proc Natl Acad Sci (USA) , vol.90 , pp. 6429-6433
    • Cumano, A.1    Furlonger, C.2    Paige, C.J.3
  • 16
    • 0028842147 scopus 로고
    • Emergence of multipotent hemopoietic cells in the yolk sac and paraaortic splanchnopleura in mouse embryos, beginning at 8.5 days postcoitus
    • Godin I, Dieterlen-Lievre F, Cumano A. Emergence of multipotent hemopoietic cells in the yolk sac and paraaortic splanchnopleura in mouse embryos, beginning at 8.5 days postcoitus. Proc Natl Acad Sci (USA) 1995; 92: 773-777.
    • (1995) Proc Natl Acad Sci (USA) , vol.92 , pp. 773-777
    • Godin, I.1    Dieterlen-Lievre, F.2    Cumano, A.3
  • 17
    • 0034813102 scopus 로고    scopus 로고
    • Intraembryonic, but not yolk sac hematopoietic precursors, isolated before circulation, provide long-term multilineage reconstitution
    • Cumano A, Ferraz JC, Klaine M, Di Santo JP, Godin I. Intraembryonic, but not yolk sac hematopoietic precursors, isolated before circulation, provide long-term multilineage reconstitution. Immunity 2001; 15: 477-485.
    • (2001) Immunity , vol.15 , pp. 477-485
    • Cumano, A.1    Ferraz, J.C.2    Klaine, M.3    Di Santo, J.P.4    Godin, I.5
  • 18
    • 35548978802 scopus 로고    scopus 로고
    • Circulation plays an essential role in distributing mammalian yolk sac definitive hematopoietic progenitor cells to the embryo proper; Using the ncx1 knockout mouse model to prevent circulation
    • Lux C, McGrath K, Conway S, Palis J, Yoder MC. Circulation plays an essential role in distributing mammalian yolk sac definitive hematopoietic progenitor cells to the embryo proper; Using the ncx1 knockout mouse model to prevent circulation. Blood 2005; 106 154a.
    • (2005) Blood , vol.106
    • Lux, C.1    McGrath, K.2    Conway, S.3    Palis, J.4    Yoder, M.C.5
  • 19
    • 35548940956 scopus 로고    scopus 로고
    • Rac1 regulates migration of yolk sac hematopoietic progenitors into the blood, a process essential for subsequent seeding of fetal liver hematopoiesis
    • Ghiaur G, Ferkowicz MJ, Bailey J, Yoder MC, Williams DA. Rac1 regulates migration of yolk sac hematopoietic progenitors into the blood, a process essential for subsequent seeding of fetal liver hematopoiesis. Blood 2005; 106: 154a.
    • (2005) Blood , vol.106
    • Ghiaur, G.1    Ferkowicz, M.J.2    Bailey, J.3    Yoder, M.C.4    Williams, D.A.5
  • 20
    • 0035412395 scopus 로고    scopus 로고
    • Generation of definitive hematopoietic stem cells from murine early yolk sac and paraaortic splanchnopleures by aorta-gonad-mesonephros region-derived stromal cells
    • Matsuoka S, Tsuji K, Hisakawa H, Xu M, Ebihara Y, Ishii T et al. Generation of definitive hematopoietic stem cells from murine early yolk sac and paraaortic splanchnopleures by aorta-gonad-mesonephros region-derived stromal cells. Blood 2001; 98: 6-12.
    • (2001) Blood , vol.98 , pp. 6-12
    • Matsuoka, S.1    Tsuji, K.2    Hisakawa, H.3    Xu, M.4    Ebihara, Y.5    Ishii, T.6
  • 21
    • 0036848557 scopus 로고    scopus 로고
    • Quantitative developmental anatomy of definitive haematopoietic stem cells/long-term repopulating units (HSC/RUs); role of the aorta-gonad-mesonephros (AGM) region and the yolk sac in colonisation of the mouse embryonic liver
    • Kumaravelu P, Hook L, Morrison AM, Ure J, Zhao S, Zuyev S et al. Quantitative developmental anatomy of definitive haematopoietic stem cells/long-term repopulating units (HSC/RUs); role of the aorta-gonad-mesonephros (AGM) region and the yolk sac in colonisation of the mouse embryonic liver. Development 2002; 129: 4891-4899.
    • (2002) Development , vol.129 , pp. 4891-4899
    • Kumaravelu, P.1    Hook, L.2    Morrison, A.M.3    Ure, J.4    Zhao, S.5    Zuyev, S.6
  • 22
    • 34247601504 scopus 로고    scopus 로고
    • Cell tracing shows the contribution of the yolk sac to adult haematopoiesis
    • Samokhvalov IM, Samokhvalova NI, Nishikawa S. Cell tracing shows the contribution of the yolk sac to adult haematopoiesis. Nature 2007; 446: 1056-1061.
    • (2007) Nature , vol.446 , pp. 1056-1061
    • Samokhvalov, I.M.1    Samokhvalova, N.I.2    Nishikawa, S.3
  • 25
    • 14644437071 scopus 로고    scopus 로고
    • The murine placenta contains hematopoietic stem cells within the vascular labyrinth region
    • Ottersbach K, Dzierzak E. The murine placenta contains hematopoietic stem cells within the vascular labyrinth region. Dev Cell 2005; 8: 377-387.
    • (2005) Dev Cell , vol.8 , pp. 377-387
    • Ottersbach, K.1    Dzierzak, E.2
  • 26
    • 33645469482 scopus 로고    scopus 로고
    • Stem calls and their niches
    • Moore KA, Lemischka IR. Stem calls and their niches. Science 2006; 311: 1880-1885.
    • (2006) Science , vol.311 , pp. 1880-1885
    • Moore, K.A.1    Lemischka, I.R.2
  • 27
    • 0034177619 scopus 로고    scopus 로고
    • Expansion of hematopoietic stem cells in the developing liver of a mouse embryo
    • Ema H, Nakauchi H. Expansion of hematopoietic stem cells in the developing liver of a mouse embryo. Blood 2000; 95: 2284-2288.
    • (2000) Blood , vol.95 , pp. 2284-2288
    • Ema, H.1    Nakauchi, H.2
  • 28
    • 0031008521 scopus 로고    scopus 로고
    • In vitro maintenance of highly purified, transplantable hematopoietic stem cells
    • Moore KA, Ema H, Lemischka IR. In vitro maintenance of highly purified, transplantable hematopoietic stem cells. Blood 1997; 89: 4337-4347.
    • (1997) Blood , vol.89 , pp. 4337-4347
    • Moore, K.A.1    Ema, H.2    Lemischka, I.R.3
  • 30
    • 1642371165 scopus 로고    scopus 로고
    • Insulin-like growth factor 2 expressed in a novel fetal liver cell population is a growth factor for hematopoletic stem cells
    • Zhang CC, Lodish HF. Insulin-like growth factor 2 expressed in a novel fetal liver cell population is a growth factor for hematopoletic stem cells. Blood 2004; 103: 2513-2521.
    • (2004) Blood , vol.103 , pp. 2513-2521
    • Zhang, C.C.1    Lodish, H.F.2
  • 31
    • 32244436673 scopus 로고    scopus 로고
    • Angiopoietin-like proteins stimulate ex vivo expansion of hematopoietic stem cells
    • Zhang CC, Kaba M, Ge G, Xie K, Tong W, Hug C et al. Angiopoietin-like proteins stimulate ex vivo expansion of hematopoietic stem cells. Nat Med 2006; 12: 240-245.
    • (2006) Nat Med , vol.12 , pp. 240-245
    • Zhang, C.C.1    Kaba, M.2    Ge, G.3    Xie, K.4    Tong, W.5    Hug, C.6
  • 32
    • 0030914867 scopus 로고    scopus 로고
    • Quiescence, cycling, and turnover in the primitive hematopoietic stem cell compartment
    • Bradford GB, Williams B, Rossi R, Bertoncello I. Quiescence, cycling, and turnover in the primitive hematopoietic stem cell compartment. Exp Hematol 1997; 25: 445-453.
    • (1997) Exp Hematol , vol.25 , pp. 445-453
    • Bradford, G.B.1    Williams, B.2    Rossi, R.3    Bertoncello, I.4
  • 33
    • 0032980506 scopus 로고    scopus 로고
    • In vivo proliferation and cell cycle kinetics of long-term self-renewing hematopoietic stem cells
    • Cheshier SH, Morrison SJ, Liao X, Weissman IL. In vivo proliferation and cell cycle kinetics of long-term self-renewing hematopoietic stem cells. Proc Natl Acad Sci (USA) 1999; 96: 3120-3125.
    • (1999) Proc Natl Acad Sci (USA) , vol.96 , pp. 3120-3125
    • Cheshier, S.H.1    Morrison, S.J.2    Liao, X.3    Weissman, I.L.4
  • 34
    • 28544436371 scopus 로고    scopus 로고
    • Global analysis of proliferation and cell cycle gene-expression in the regulation of hematopoietic stem and progenitor cell fates
    • Passegue E, Wagers AJ, Giuriato S, Anderson WC, Weissman IL. Global analysis of proliferation and cell cycle gene-expression in the regulation of hematopoietic stem and progenitor cell fates. J Exp Med 2005; 202: 1599-1611.
    • (2005) J Exp Med , vol.202 , pp. 1599-1611
    • Passegue, E.1    Wagers, A.J.2    Giuriato, S.3    Anderson, W.C.4    Weissman, I.L.5
  • 35
    • 34249056493 scopus 로고    scopus 로고
    • High incidence of non-random template strand segregation and asymmetric fate determination in dividing stem cells and their progeny
    • Conboy MJ, Karasov AO, Rando TA. High incidence of non-random template strand segregation and asymmetric fate determination in dividing stem cells and their progeny. PLoS Biol 2007; 5: E102.
    • (2007) PLoS Biol , vol.5
    • Conboy, M.J.1    Karasov, A.O.2    Rando, T.A.3
  • 36
    • 0018102359 scopus 로고
    • The relationship between the spleen colony-forming cell and tha haemopoietic stem cell
    • Schofield R. The relationship between the spleen colony-forming cell and tha haemopoietic stem cell. Blood Cells 1978; 4: 7-25.
    • (1978) Blood Cells , vol.4 , pp. 7-25
    • Schofield, R.1
  • 37
    • 33644827383 scopus 로고    scopus 로고
    • Bone-marrow haematopoietic-stem-cell niches
    • Wilson A, Trumpp A. Bone-marrow haematopoietic-stem-cell niches. Nat Rev Immunol 2006; 6: 93-106.
    • (2006) Nat Rev Immunol , vol.6 , pp. 93-106
    • Wilson, A.1    Trumpp, A.2
  • 38
    • 0035991663 scopus 로고    scopus 로고
    • Transplanted hematopoietic cells seed in clusters in recipient bone marrow in vivo
    • Askenasy N, Zorina T, Farkas DL, Shalit I. Transplanted hematopoietic cells seed in clusters in recipient bone marrow in vivo. Stem Cells 2002; 20: 301-310.
    • (2002) Stem Cells , vol.20 , pp. 301-310
    • Askenasy, N.1    Zorina, T.2    Farkas, D.L.3    Shalit, I.4
  • 39
    • 0030051856 scopus 로고    scopus 로고
    • Human osteoblasts support human hematopoietic progenitor cells in vitro bone marrow cultures
    • Taichman RS, Reilly MJ, Emerson SG. Human osteoblasts support human hematopoietic progenitor cells in vitro bone marrow cultures. Blood 1996; 87: 518-524.
    • (1996) Blood , vol.87 , pp. 518-524
    • Taichman, R.S.1    Reilly, M.J.2    Emerson, S.G.3
  • 40
    • 0242363225 scopus 로고    scopus 로고
    • Identification of the haematopoietic stem cell niche and control of the niche size
    • Zhang J, Niu C, Ye L, Huang H, He X, Tong WG et al. Identification of the haematopoietic stem cell niche and control of the niche size. Nature 2003; 425: 836-841.
    • (2003) Nature , vol.425 , pp. 836-841
    • Zhang, J.1    Niu, C.2    Ye, L.3    Huang, H.4    He, X.5    Tong, W.G.6
  • 42
    • 1942457308 scopus 로고    scopus 로고
    • Hematopoieses is severely altered in mice with an induced osteoblast deficiency
    • Visnjic D, Kalajzic Z, Rowe DW, Katavic V, Lorenzo J, Aguila HL. Hematopoieses is severely altered in mice with an induced osteoblast deficiency. Blood 2004; 103: 3258-3264.
    • (2004) Blood , vol.103 , pp. 3258-3264
    • Visnjic, D.1    Kalajzic, Z.2    Rowe, D.W.3    Katavic, V.4    Lorenzo, J.5    Aguila, H.L.6
  • 43
    • 0033672656 scopus 로고    scopus 로고
    • Fetal and adult hematopoietic stem cells require beta1 integrin function for colonizing fetal liver, spleen, and bone marrow
    • Potocnik AJ, Brakebusch C, Fassler R. Fetal and adult hematopoietic stem cells require beta1 integrin function for colonizing fetal liver, spleen, and bone marrow: Immunity 2000; 12: 653-663.
    • (2000) Immunity , vol.12 , pp. 653-663
    • Potocnik, A.J.1    Brakebusch, C.2    Fassler, R.3
  • 44
    • 3242669145 scopus 로고    scopus 로고
    • Ti/ angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche
    • Arai F, Hirao A, Ohmura M, Sato H, Matsuoka S, Takubo K et al. Ti/ angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche. Cell 2004; 118: 149-161.
    • (2004) Cell , vol.118 , pp. 149-161
    • Arai, F.1    Hirao, A.2    Ohmura, M.3    Sato, H.4    Matsuoka, S.5    Takubo, K.6
  • 45
    • 0242331643 scopus 로고    scopus 로고
    • Requirement for the TIE family of receptor tyrosine kinases in adult but not fetal hematopoiessis
    • Puri MC, Bemstein A. Requirement for the TIE family of receptor tyrosine kinases in adult but not fetal hematopoiessis. Proc Natl Acad Sci USA 2003; 100: 12753-12758.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 12753-12758
    • Puri, M.C.1    Bemstein, A.2
  • 48
    • 21244463426 scopus 로고    scopus 로고
    • SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells
    • Kiel MJ, Yilmaz OH, Iwashita T, Yilmaz OH, Terhorst C, Morrison SJ. SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells. Cell 2005; 121: 1109-1121.
    • (2005) Cell , vol.121 , pp. 1109-1121
    • Kiel, M.J.1    Yilmaz, O.H.2    Iwashita, T.3    Yilmaz, O.H.4    Terhorst, C.5    Morrison, S.J.6
  • 49
    • 33845445939 scopus 로고    scopus 로고
    • Maintenance of the hematopoietic stem cell pool by CXCL12-CXCR4 chemokine signaling in bone marrow stromal cell niches
    • Sugiyama T, Kohara H, Noda M, Nagasawa T. Maintenance of the hematopoietic stem cell pool by CXCL12-CXCR4 chemokine signaling in bone marrow stromal cell niches. Immunity 2006; 25: 977-988.
    • (2006) Immunity , vol.25 , pp. 977-988
    • Sugiyama, T.1    Kohara, H.2    Noda, M.3    Nagasawa, T.4
  • 50
    • 33645533796 scopus 로고    scopus 로고
    • Lack of alpha4 Integrin expression in stem cells restricts competitive function and self-renewal activity
    • Priestley, GV, Scott LM, Ulyanova T, Papayannopoulou T. Lack of alpha4 Integrin expression in stem cells restricts competitive function and self-renewal activity. Blood 2006; 107: 2959-2967.
    • (2006) Blood , vol.107 , pp. 2959-2967
    • Priestley, G.V.1    Scott, L.M.2    Ulyanova, T.3    Papayannopoulou, T.4
  • 51
    • 0036529989 scopus 로고    scopus 로고
    • Notch1 activation increases hematopoietic stem cell self-renewal in vivo and favors lymphoid over myeloid lineage outcome
    • Stier S, Cheng T, Dombkowski D, Carlesso N, Scadden DT. Notch1 activation increases hematopoietic stem cell self-renewal in vivo and favors lymphoid over myeloid lineage outcome. Blood 2002; 99: 2369-2378.
    • (2002) Blood , vol.99 , pp. 2369-2378
    • Stier, S.1    Cheng, T.2    Dombkowski, D.3    Carlesso, N.4    Scadden, D.T.5
  • 53
    • 15244346226 scopus 로고    scopus 로고
    • Jagged1-dependent Notch signaling is dispensable for hematopoietic stem cell self-renewal and differentiation
    • Mancini SJ, Mantei N, Dumortier A, Suter U, MacDonald HR, Radtke F. Jagged1-dependent Notch signaling is dispensable for hematopoietic stem cell self-renewal and differentiation. Blood 2005; 105: 2340-2342.
    • (2005) Blood , vol.105 , pp. 2340-2342
    • Mancini, S.J.1    Mantei, N.2    Dumortier, A.3    Suter, U.4    MacDonald, H.R.5    Radtke, F.6
  • 54
    • 0037737728 scopus 로고    scopus 로고
    • A role for Wnt signalling in self-renewal of haematopoietic stem cells
    • Reya T, Duncan AW, Aillies L, Domen J, Scherer DC, Willert K et al. A role for Wnt signalling in self-renewal of haematopoietic stem cells. Nature 2003; 423: 409-414.
    • (2003) Nature , vol.423 , pp. 409-414
    • Reya, T.1    Duncan, A.W.2    Aillies, L.3    Domen, J.4    Scherer, D.C.5    Willert, K.6
  • 55
    • 4644274431 scopus 로고    scopus 로고
    • TeVEtv6 is an essential and selective regulator of adult hematopoietic stem cell survival
    • Hock H, Meade E, Medeiros S, Schindler JW, Valk PJ, Fujiwara Y et al. TeVEtv6 is an essential and selective regulator of adult hematopoietic stem cell survival. Genes Dev 2004; 18: 2336-2341.
    • (2004) Genes Dev , vol.18 , pp. 2336-2341
    • Hock, H.1    Meade, E.2    Medeiros, S.3    Schindler, J.W.4    Valk, P.J.5    Fujiwara, Y.6
  • 56
    • 5444224800 scopus 로고    scopus 로고
    • In vitro and in vivo expansion of hematopoietic stem cells
    • Sauvageau G, Iscove NN, Humphries RK. In vitro and in vivo expansion of hematopoietic stem cells. Oncogene 2004; 23: 7223-7232.
    • (2004) Oncogene , vol.23 , pp. 7223-7232
    • Sauvageau, G.1    Iscove, N.N.2    Humphries, R.K.3
  • 57
    • 2542467750 scopus 로고    scopus 로고
    • Hoxb4-deficient mice undergo normal hematopoietic development but exhibit a mild proliferation defect in hematopoietic stem cells
    • Brun AC, Bjornsson JM, Magnusson M, Larsson N, Leveen P, Ehinger M et al. Hoxb4-deficient mice undergo normal hematopoietic development but exhibit a mild proliferation defect in hematopoietic stem cells. Blood 2004; 103: 4126-4133.
    • (2004) Blood , vol.103 , pp. 4126-4133
    • Brun, A.C.1    Bjornsson, J.M.2    Magnusson, M.3    Larsson, N.4    Leveen, P.5    Ehinger, M.6
  • 58
    • 8144220648 scopus 로고    scopus 로고
    • Transcription factor Gfi1 regulates self-renewal and angraftment of hematopoietic stem cells
    • Zeng H, Yucel R, Kosan C, Klein-Hitpass L, Moroy T. Transcription factor Gfi1 regulates self-renewal and angraftment of hematopoietic stem cells. EMBO J 2004; 23: 4116-4125.
    • (2004) EMBO J , vol.23 , pp. 4116-4125
    • Zeng, H.1    Yucel, R.2    Kosan, C.3    Klein-Hitpass, L.4    Moroy, T.5
  • 59
    • 7244231429 scopus 로고    scopus 로고
    • Gfi-1 restricts proliferation and preserves functional integrity of haematopoietic stem calls
    • Hock H, Hamblen MJ, Rooke HM, Schindler JW, Saleque S, Fujiwara Y et al. Gfi-1 restricts proliferation and preserves functional integrity of haematopoietic stem calls. Nature 2004; 431: 1002-1007.
    • (2004) Nature , vol.431 , pp. 1002-1007
    • Hock, H.1    Hamblen, M.J.2    Rooke, H.M.3    Schindler, J.W.4    Saleque, S.5    Fujiwara, Y.6
  • 60
  • 61
    • 2342601849 scopus 로고    scopus 로고
    • In vivo self-renewing divisions of haematopoietic stem cells are increased in the absence of the early G1-phase inhibitor, p18INK4C
    • Yuan Y, Shen H, Franklin DS, Scadden DT, Cheng T. In vivo self-renewing divisions of haematopoietic stem cells are increased in the absence of the early G1-phase inhibitor, p18INK4C. Nat Cell Biol 2004; 6: 436-442.
    • (2004) Nat Cell Biol , vol.6 , pp. 436-442
    • Yuan, Y.1    Shen, H.2    Franklin, D.S.3    Scadden, D.T.4    Cheng, T.5
  • 62
    • 31544463261 scopus 로고    scopus 로고
    • Hematopoietic stem cell exhaustion impacted by p18 INK4C and p21 Cip1/Waf1 in opposite manners
    • Yu H, Yuan Y, Shen H, Cheng T. Hematopoietic stem cell exhaustion impacted by p18 INK4C and p21 Cip1/Waf1 in opposite manners. Blood 2006; 107: 1200-1206.
    • (2006) Blood , vol.107 , pp. 1200-1206
    • Yu, H.1    Yuan, Y.2    Shen, H.3    Cheng, T.4
  • 63
    • 22344444393 scopus 로고    scopus 로고
    • Selective activation of STAT5 unveils its role in stem cell self-renewal in normal and leukemic hematopoiesis
    • Kato Y, Iwama A, Tadokoro Y, Shimoda K, Minoguchi M, Aldra S et al. Selective activation of STAT5 unveils its role in stem cell self-renewal in normal and leukemic hematopoiesis. J Exp Med 2005; 202: 169-179.
    • (2005) J Exp Med , vol.202 , pp. 169-179
    • Kato, Y.1    Iwama, A.2    Tadokoro, Y.3    Shimoda, K.4    Minoguchi, M.5    Aldra, S.6
  • 64
    • 33747204587 scopus 로고    scopus 로고
    • Unique effects of Stat3 on the early phase of hematopoietic stem cell regeneration
    • Chung YJ, Park BB, Kang YJ, Kim TM, Eaves CJ, Oh IH. Unique effects of Stat3 on the early phase of hematopoietic stem cell regeneration. Blood 2006; 108: 1208-1215.
    • (2006) Blood , vol.108 , pp. 1208-1215
    • Chung, Y.J.1    Park, B.B.2    Kang, Y.J.3    Kim, T.M.4    Eaves, C.J.5    Oh, I.H.6
  • 65
    • 10344258563 scopus 로고    scopus 로고
    • Enhanced self-renewal of hematopoietic stem cells mediated by the polycomb gene product Bmi-1
    • Iwama A, Oguro H, Negishi M, Kato Y, Morita, Y, Tsukui H et al. Enhanced self-renewal of hematopoietic stem cells mediated by the polycomb gene product Bmi-1. Immunity 2004; 21: 843-851.
    • (2004) Immunity , vol.21 , pp. 843-851
    • Iwama, A.1    Oguro, H.2    Negishi, M.3    Kato, Y.4    Morita, Y.5    Tsukui, H.6
  • 66
    • 0037128662 scopus 로고    scopus 로고
    • Polycomb group gene rae28 is required for sustaining activity of hemapoietic stem cells
    • Ohta H, Sawada A, Kim JY, Tokimasa S, Nishiguchi S, Humphries RK et al. Polycomb group gene rae28 is required for sustaining activity of hemapoietic stem cells. J Exp Med 2002; 195: 759-770.
    • (2002) J Exp Med , vol.195 , pp. 759-770
    • Ohta, H.1    Sawada, A.2    Kim, J.Y.3    Tokimasa, S.4    Nishiguchi, S.5    Humphries, R.K.6
  • 67
    • 0038349957 scopus 로고    scopus 로고
    • Bmi-1 is required for maintainance.of adult self-renewing haematopoietic stem cells
    • Park IK, Qian D, Kiel M, Becker MW, Pihalja M, Weissman IL et al. Bmi-1 is required for maintainance.of adult self-renewing haematopoietic stem cells. Nature 2003; 423: 302-305.
    • (2003) Nature , vol.423 , pp. 302-305
    • Park, I.K.1    Qian, D.2    Kiel, M.3    Becker, M.W.4    Pihalja, M.5    Weissman, I.L.6
  • 68
    • 33748859509 scopus 로고    scopus 로고
    • Hematopoletic stem cell and multillineage defects generated by constitutive beta-catenin activation
    • Scheller M, Huelsken J, Rosenbauer F, Taketo MM, Birchmeier W, Tenen DG et al. Hematopoletic stem cell and multillineage defects generated by constitutive beta-catenin activation. Nat Immunol 2006; 7 1037-1047.
    • (2006) Nat Immunol , vol.7 , pp. 1037-1047
    • Scheller, M.1    Huelsken, J.2    Rosenbauer, F.3    Taketo, M.M.4    Birchmeier, W.5    Tenen, D.G.6
  • 70
    • 33748850636 scopus 로고    scopus 로고
    • Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block
    • Kirstetter P, Anderson K, Porse BT, Jacobson SE, Nerlov C. Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block. Nat Imumnol 2006; 7: 1048-1056.
    • (2006) Nat Imumnol , vol.7 , pp. 1048-1056
    • Kirstetter, P.1    Anderson, K.2    Porse, B.T.3    Jacobson, S.E.4    Nerlov, C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.