Oscillations in cerebral blood flow and cortical oxygenation in Alzheimer's disease

Neurobiology of Aging

Volumn 33, Issue 2, 2012, Pages 428.e21-428.e31

  van Beek, Arenda H E A ^a   Lagro, Joep ^a   Olde Rikkert, Marcel G M ^a   Zhang, Rong ^b   Claassen, Jurgen A H R ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b Institute for Exercise and Environmental Medicine Dallas   (United States)

Author keywords

Alzheimer's disease; Brain tissue oxygenation; Cerebral autoregulation; Cerebrovascular disease; Near infrared spectroscopy; Transcranial Doppler sonography

Indexed keywords

ANGIOTENSIN II ANTAGONIST; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM CHANNEL BLOCKING AGENT; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; HEMOGLOBIN;

AGED; ALZHEIMER DISEASE; ARTICLE; AUTOREGULATION; BLOOD PRESSURE MEASUREMENT; BRAIN BLOOD FLOW; BRAIN VASCULAR RESISTANCE; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; DOPPLER ECHOGRAPHY; FEMALE; HUMAN; HYPERTENSION; MALE; MICROVASCULATURE; NEAR INFRARED SPECTROSCOPY; OSCILLATION; OUTCOME ASSESSMENT; PRIORITY JOURNAL; TISSUE OXYGENATION;

EID: 79959845860     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2010.11.016     Document Type: Article

References (36)

1. Aaslid R., Markwalder T.M., Nornes H. Noninvasive transcranial Doppler ultrasound recording of flow velocity in basal cerebral arteries. J. Neurosurg 1982, 57:769-774.
2. Brown C.M., Marthol H., Zikeli U., Ziegler D., Hilz M.J. A simple deep breathing test reveals altered cerebral autoregulation in type 2 diabetic patients. Diabetologia 2008, 51:756-761.
3. Chow N., Bell R.D., Deane R., Streb J.W., Chen J., Brooks A., Van N.W., Miano J.M., Zlokovic B.V. Serum response factor and myocardin mediate arterial hypercontractility and cerebral blood flow dysregulation in Alzheimer's phenotype. Proc. Natl. Acad. Sci. U. S. A. 2007, 104:823-828.
4. Claassen J.A., az-Arrastia R., Martin-Cook K., Levine B.D., Zhang R. Altered cerebral hemodynamics in early Alzheimer disease: a pilot study using transcranial doppler. J. Alzheimers Dis 2009, 17:621-629.
5. Claassen J.A., Colier W.N., Jansen R.W. Reproducibility of cerebral blood volume measurements by near infrared spectroscopy in 16 healthy elderly subjects. Physiol. Meas 2006, 27:255-264.
6. Claassen J.A., Levine B.D., Zhang R. Dynamic cerebral autoregulation during repeated squat-stand maneuvers. J. Appl. Physiol 2009, 106:153-160.
7. Claassen J.A., van Beek A.H., Olde R.M.G. Short review: acetylcholinesterase-inhibitors in Alzheimer's disease have opposing effects on blood pressure and cerebral perfusion. J. Nutr. Health Aging 2009, 13:231-233.
8. Estrup T.M., Paulson O.B., Strandgaard S. No effect of angiotensin II AT(2)-receptor antagonist PD 123319 on cerebral blood flow autoregulation. J. Renin Angiotensin Aldosterone Syst 2001, 2:188-192.
9. Farkas E., Luiten P.G. Cerebral microvascular pathology in aging and Alzheimer's disease. Prog. Neurobiol 2001, 64:575-611.
10. Giller C.A., Bowman G., Dyer H., Mootz L., Krippner W. Cerebral arterial diameters during changes in blood pressure and carbon dioxide during craniotomy. Neurosurgery 1993, 32:737-741.
11. Giller C.A., Mueller M. Linearity and non-linearity in cerebral hemodynamics. Med. Eng. Phys 2003, 25:633-646.
12. Hamner J.W., Cohen M.A., Mukai S., Lipsitz L.A., Taylor J.A. Spectral indices of human cerebral blood flow control: responses to augmented blood pressure oscillations. J. Physiol 2004, 559:965-973.
13. Han B.H., Zhou M.L., Abousaleh F., Brendza R.P., Dietrich H.H., Koenigsknecht-Talboo J., Cirrito J.R., Milner E., Holtzman D.M., Zipfel G.J. Cerebrovascular dysfunction in amyloid precursor protein transgenic mice: contribution of soluble and insoluble amyloid-beta peptide, partial restoration via gamma-secretase inhibition. J. Neurosci 2008, 28:13542-13550.
14. Heinke W., Zysset S., Hund-Georgiadis M., Olthoff D., von Cramon D.Y. The effect of esmolol on cerebral blood flow, cerebral vasoreactivity, and cognitive performance: a functional magnetic resonance imaging study. Anesthesiology 2005, 102:41-50.
15. Iadecola C., Park L., Capone C. Threats to the mind: aging, amyloid, and hypertension. Stroke 2009, 40:S40-S44.
16. Kim Y.S., Immink R.V., Stok W.J., Karemaker J.M., Secher N.H., Van Lieshout J.J. Dynamic cerebral autoregulatory capacity is affected early in Type 2 diabetes. Clin. Sci. Lond 2008, 115:255-262.
17. Lipsitz L.A., Mukai S., Hamner J., Gagnon M., Babikian V. Dynamic regulation of middle cerebral artery blood flow velocity in aging and hypertension. Stroke 2000, 31:1897-1903.
18. Mandeville J.B., Marota J.J., Ayata C., Zaharchuk G., Moskowitz M.A., Rosen B.R., Weisskoff R.M. Evidence of a cerebrovascular postarteriole windkessel with delayed compliance. J. Cereb. Blood Flow Metab 1999, 19:679-689.
19. Marthol H., Zikeli U., Brown C.M., Tutaj M., Hilz M.J. Cardiovascular and cerebrovascular responses to lower body negative pressure in type 2 diabetic patients. J. Neurol. Sci 2007, 252:99-105.
20. McKhann G., Drachman D., Folstein M., Katzman R., Price D., Stadlan E.M. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 1984, 34:939-944.
21. Nagata K., Sato M., Satoh Y., Watahiki Y., Kondoh Y., Sugawara M., Box G., Wright D., Leung S., Yuya H., Shimosegawa E. Hemodynamic aspects of Alzheimer's disease. Ann. N. Y. Acad. Sci 2002, 977:391-402.
22. Newell D.W., Aaslid R., Lam A., Mayberg T.S., Winn H.R. Comparison of flow and velocity during dynamic autoregulation testing in humans. Stroke 1994, 25:793-797.
23. Obrig H., Neufang M., Wenzel R., Kohl M., Steinbrink J., Einhaupl K., Villringer A. Spontaneous low frequency oscillations of cerebral hemodynamics and metabolism in human adults. Neuroimage 2000, 12:623-639.
24. Pandita-Gunawardena N.D., Clarke S.E. Amlodipine lowers blood pressure without affecting cerebral blood flow as measured by single photon emission computed tomography in elderly hypertensive subjects. Age Ageing 1999, 28:451-457.
25. Reinhard M., Wehrle-Wieland E., Grabiak D., Roth M., Guschlbauer B., Timmer J., Weiller C., Hetzel A. Oscillatory cerebral hemodynamics-the macro- vsmicrovascular level. J. Neurol. Sci 2006, 250:103-109.
26. Rowley A.B., Payne S.J., Tachtsidis I., Ebden M.J., Whiteley J.P., Gavaghan D.J., Tarassenko L., Smith M., Elwell C.E., Delpy D.T. Synchronization between arterial blood pressure and cerebral oxyhaemoglobin concentration investigated by wavelet cross-correlation. Physiol. Meas 2007, 28:161-173.
27. Schroeter M.L., Schmiedel O., von Cramon D.Y. Spontaneous low-frequency oscillations decline in the aging brain. J. Cereb. Blood Flow Metab 2004, 24:1183-1191.
28. Serrador J.M., Picot P.A., Rutt B.K., Shoemaker J.K., Bondar R.L. MRI measures of middle cerebral artery diameter in conscious humans during simulated orthostasis. Stroke 2000, 31:1672-1678.
29. van Beek A.H., Claassen J.A., Rikkert M.G., Jansen R.W. Cerebral autoregulation: an overview of current concepts and methodology with special focus on the elderly. J. Cereb. Blood Flow Metab 2008, 28:1071-1085.
30. van Beek A.H., Olde R.M.G., Pasman J.W., Hopman M.T., Claassen J.A. Dynamic cerebral autoregulation in the old using a repeated sit-stand maneuver. Ultrasound Med. Biol 2010, 36:192-201.
31. Viswanathan A., Rocca W.A., Tzourio C. Vascular risk factors and dementia: how to move forward?. Neurology 2009, 72:368-374.
32. Wu Z., Guo H., Chow N., Sallstrom J., Bell R.D., Deane R., Brooks A.I., Kanagala S., Rubio A., Sagare A., Liu D., Li F., Armstrong D., Gasiewicz T., Zidovetzki R., Song X., Hofman F., Zlokovic B.V. Role of the MEOX2 homeobox gene in neurovascular dysfunction in Alzheimer disease. Nat. Med 2005, 11:959-965.
33. Zhang R., Behbehani K., Levine B.D. Dynamic pressure-flow relationship of the cerebral circulation during acute increase in arterial pressure. J. Physiol 2009, 587:2567-2577.
34. Zhang R., Witkowski S., Fu Q., Claassen J.A., Levine B.D. Cerebral Hemodynamics After Short- and Long-Term Reduction in Blood Pressure in Mild and Moderate Hypertension. Hypertension 2007, 49:1149-1155.
35. Zhang R., Zuckerman J.H., Giller C.A., Levine B.D. Transfer function analysis of dynamic cerebral autoregulation in humans. Am. J. Physiol 1998, 274:H233-H241.
36. Zlokovic B.V., Yamada S., Holtzman D., Ghiso J., Frangione B. Clearance of amyloid beta-peptide from brain: transport or metabolism?. Nat. Med 2000, 6:718.