Plasticity of CYP2B enzymes: Structural and solution biophysical methods

Current Drug Metabolism

Volumn 13, Issue 2, 2012, Pages 167-176

  Wilderman, P Ross ^a   Halpert, James R ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

Crystallography; CYP2B; Cytochrome P450; Deuterium exchange mass spectrometry; Molecular dynamics simulation; Molecular modeling; NMR

Indexed keywords

BIFONAZOLE; CLOPIDOGREL; CYTOCHROME P450 2B; LEUCINE; TICLOPIDINE; TYROSINE;

ARTICLE; BINDING AFFINITY; CRYSTAL STRUCTURE; CRYSTALLIZATION; DENSITY; DIMERIZATION; ELECTRON TRANSPORT; ENZYME ACTIVE SITE; HYDROGEN BOND; HYDROPHOBICITY; LIGAND BINDING; MASS SPECTROMETRY; MOLECULAR DOCKING; MOLECULAR DYNAMICS; NUCLEAR MAGNETIC RESONANCE; OXIDATION; PLASTICITY; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN ENGINEERING; PROTEIN EXPRESSION; PROTEIN STABILITY; PROTEIN STRUCTURE; SITE DIRECTED MUTAGENESIS; X RAY CRYSTALLOGRAPHY;

ANIMALS; ARYL HYDROCARBON HYDROXYLASES; CRYSTALLOGRAPHY, X-RAY; HUMANS; MODELS, MOLECULAR; PROTEIN CONFORMATION; PROTEIN ENGINEERING; SPECTRUM ANALYSIS; STEROID HYDROXYLASES;

EID: 84857539181     PISSN: 13892002     EISSN: 18755453     Source Type: Journal    
DOI: 10.2174/138920012798918417     Document Type: Article

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