Unrestrained mammalian target of rapamycin complexes 1 and 2 increase expression of phosphatase and tensin homolog deleted on chromosome 10 to regulate phosphorylation of Akt kinase

Journal of Biological Chemistry

Volumn 287, Issue 6, 2012, Pages 3808-3822

  Das, Falguni ^b   Ghosh Choudhury, Nandini ^a,b   Dey, Nirmalya ^b   Mandal, Chandi Charan ^b   Mahimainathan, Lenin ^b   Kasinath, Balakuntalam S ^b   Abboud, Hanna E ^b   Choudhury, Goutam Ghosh ^a,b  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^b Mays Cancer Center at UT Health San Antonio   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

293 CELLS; AKT PHOSPHORYLATION; AUTOSOMAL DOMINANTS; CELL-AUTONOMOUS FUNCTION; COMPLEX 1; CONSTITUTIVELY ACTIVES; DOWN-REGULATION; HAMARTOMA; HYDROPHOBIC MOTIF SITES; INSULIN RESISTANCE; MAMMALIAN TARGET; MAMMALIAN TARGET OF RAPAMYCIN (MTOR); MOUSE EMBRYONIC FIBROBLASTS; PTEN EXPRESSION; RAPAMYCIN; TRANSCRIPTIONAL MECHANISMS; TUBEROUS SCLEROSIS; UP-REGULATION;

CELL CULTURE; CHROMOSOMES; FIBROBLASTS; MAMMALS; PHOSPHATASES; PHOSPHORYLATION; TRANSCRIPTION FACTORS;

ANTIBIOTICS;

HYPOXIA INDUCIBLE FACTOR 1ALPHA; MAMMALIAN TARGET OF RAPAMYCIN; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 2; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; RAPAMYCIN; TUBERIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; EMBRYO; FIBROBLAST; GENE EXPRESSION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; TRANSCRIPTION REGULATION; TRANSLATION REGULATION;

ANIMALS; CHROMOSOMES, HUMAN, PAIR 10; EMBRYO, MAMMALIAN; FIBROBLASTS; GENE DELETION; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MICE; MICE, KNOCKOUT; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TUBEROUS SCLEROSIS; TUMOR SUPPRESSOR PROTEINS; UP-REGULATION;

MAMMALIA; RAPTORES;

EID: 84856701139     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.246397     Document Type: Article

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