Differential transcriptional profiles mediated by exposure to the cannabinoids cannabidiol and Δ 9-tetrahydrocannabinol in BV-2 microglial cells

British Journal of Pharmacology

Volumn 165, Issue 8, 2012, Pages 2512-2528

  Juknat, Ana ^a   Pietr, Maciej ^b   Kozela, Ewa ^a   Rimmerman, Neta ^b   Levy, Rivka ^b   Coppola, Giovanni ^c   Geschwind, Daniel ^c   Vogel, Zvi ^a,b  

^a TEL AVIV UNIVERSITY   (Israel)

^b WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

9 tetrahydrocannabinol; Cannabidiol; Gene expression; Glutathione depletion; Nuclear factor erythroid 2 related factor 2; Oxidative stress

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; CANNABIDIOL; DRONABINOL; GLUTATHIONE; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; NUCLEAR FACTOR; PROTEASOME; PROTEIN; PROTEIN ELF2ALPHA; PROTEIN GCN2; PROTEIN HMOX1; PROTEIN P8; PROTEIN TRIB3; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ENZYME INHIBITION; GENE ACTIVATION; GENE CONTROL; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE PROBE; GENE PRODUCT; GENETIC TRANSCRIPTION; INFLAMMATION; MICROARRAY ANALYSIS; MICROGLIA; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; NUTRIENT; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEPLETION; SIGNAL TRANSDUCTION; UNINDEXED SEQUENCE; UPREGULATION;

ANIMALS; CANNABIDIOL; CELL LINE; GENE EXPRESSION PROFILING; GLUTATHIONE; MICE; MICROGLIA; OXIDATIVE STRESS; TETRAHYDROCANNABINOL; TRANSCRIPTION, GENETIC;

EID: 84856513007     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2011.01461.x     Document Type: Article

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