Cannabidiol-induced apoptosis in primary lymphocytes is associated with oxidative stress-dependent activation of caspase-8

Toxicology and Applied Pharmacology

Volumn 226, Issue 3, 2008, Pages 260-270

  Wu, Hsin Ying ^a   Chu, Rea Min ^a   Wang, Chia Chi ^a   Lee, Chi Ya ^a   Lin, Shu Hong ^a   Jan, Tong Rong ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

Apoptosis; Cannabidiol; Caspase 8; Lymphocyte; Oxidative stress; Reactive oxygen species

Indexed keywords

ACETYLCYSTEINE; CANNABIDIOL; CASPASE 8; GLUTATHIONE; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; APOPTOSIS; ARTICLE; BAGG ALBINO MOUSE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DIPLOIDY; DNA STRAND BREAKAGE; ENZYME ACTIVATION; ENZYME ACTIVITY; MOUSE; NONHUMAN; OXIDATIVE STRESS; SPLEEN CELL; T LYMPHOCYTE; TIME;

ACETYLCYSTEINE; ANIMALS; APOPTOSIS; CANNABIDIOL; CASPASE 8; CELL NUCLEUS; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; ENZYME INHIBITORS; FREE RADICAL SCAVENGERS; GLUTATHIONE; IMMUNOLOGIC FACTORS; MALE; MICE; MICE, INBRED BALB C; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; SPLEEN;

MUS;

EID: 38649110505     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2007.09.012     Document Type: Article

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