Induction of p21 and p27 expression by amino acid deprivation of HepG2 human hepatoma cells involves mRNA stabilization

Biochemical Journal

Volumn 379, Issue 1, 2004, Pages 79-88

  Leung Pineda, Van ^a   Pan, YuanXiang ^a   Chen, Hong ^a   Kilberg, Michael S ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

Amino acid starvation; Cell cycle; Cyclin dependent kinase inhibitor; Cyclins; mRNA stability; Nutrient control

Indexed keywords

AMINO ACIDS; BIOCHEMISTRY; CELL CULTURE; CELLS; GENES; IMAGE SENSORS; PROTEINS; SYNTHESIS (CHEMICAL);

HEPATOMA CELLS; PHOSPHORYLATION; TRANSACTIVATION;

RNA;

AMINO ACID; HISTIDINE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN P21; PROTEIN P27; TARGET OF RAPAMYCIN KINASE;

ARTICLE; CELL CYCLE; CELL CYCLE G1 PHASE; CONTROLLED STUDY; HEPATOMA CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; RNA STABILITY; SIGNAL TRANSDUCTION; TRANSACTIVATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; AMINO ACIDS; CARCINOMA, HEPATOCELLULAR; CELL CYCLE PROTEINS; CELL LINE, TUMOR; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLIN-DEPENDENT KINASE INHIBITOR P27; CYCLINS; ENZYME INHIBITORS; G1 PHASE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, CDC; GENES, REPORTER; HUMANS; LIVER NEOPLASMS; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; NUCLEIC ACID SYNTHESIS INHIBITORS; PROMOTER REGIONS (GENETICS); PROTEIN DEFICIENCY; PROTEIN KINASE INHIBITORS; PROTEIN KINASES; PROTEIN SYNTHESIS INHIBITORS; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA, MESSENGER; RNA, NEOPLASM; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEINS;

MAMMALIA;

EID: 1842833391     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20031383     Document Type: Article

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