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Volumn 4, Issue 3, 2011, Pages 247-259

Contribution of bone tissue modulus to breast cancer metastasis to bone

Author keywords

Breast cancer; Mechanotransduction; Modulus; PTHrP; Rigidity; Tumor induced bone disease

Indexed keywords

DENOSUMAB; FASUDIL; FIBRONECTIN; INTEGRIN; MITOGEN ACTIVATED PROTEIN KINASE; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPONTIN; PARATHYROID HORMONE RELATED PROTEIN; PROTEIN TYROSINE KINASE; RHO KINASE; TRANSCRIPTION FACTOR GLI2; TRANSCRIPTION FACTOR RUNX2; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 3; VITRONECTIN; VITRONECTIN RECEPTOR;

EID: 84856467831     PISSN: 18752292     EISSN: 18752284     Source Type: Journal    
DOI: 10.1007/s12307-011-0078-3     Document Type: Review
Times cited : (21)

References (128)
  • 5
    • 78650304106 scopus 로고    scopus 로고
    • Advances in the biology of bone metastasis: How the skeleton affects tumor behavior
    • Sterling JA, Edwards JR, Martin TJ, Mundy GR (2011) Advances in the biology of bone metastasis: how the skeleton affects tumor behavior. Bone 48:6-15
    • (2011) Bone , vol.48 , pp. 6-15
    • Sterling, J.A.1    Edwards, J.R.2    Martin, T.J.3    Mundy, G.R.4
  • 7
    • 33745588297 scopus 로고    scopus 로고
    • PARP regulates TGF-β receptor type II expression in estrogen receptor-positive breast cancer cell lines
    • Sterling JA, Wu L, Banerji SS (2006) Parp regulates tgf-beta receptor type ii expression in estrogen receptor-positive breast cancer cell lines. Anticancer Res 26:1893-1901 (Pubitemid 43989447)
    • (2006) Anticancer Research , vol.26 , Issue.3 A , pp. 1893-1901
    • Sterling, J.A.1    Wu, L.2    Banerji, S.S.3
  • 8
    • 0031974364 scopus 로고    scopus 로고
    • A kinase-defective transforming growth factor-beta receptor type ii is a dominantnegative regulator for human breast carcinoma mcf-7 cells
    • Ko Y, Koli KM, Banerji SS, Li W, Zborowska E, Willson JK, Brattain MG, Arteaga CL (1998) A kinase-defective transforming growth factor-beta receptor type ii is a dominantnegative regulator for human breast carcinoma mcf-7 cells. Int J Oncol 12:87-94
    • (1998) Int J Oncol , vol.12 , pp. 87-94
    • Ko, Y.1    Koli, K.M.2    Banerji, S.S.3    Li, W.4    Zborowska, E.5    Willson, J.K.6    Brattain, M.G.7    Arteaga, C.L.8
  • 10
    • 0034658725 scopus 로고    scopus 로고
    • Molecular mechanism of osteolytic bone metastases
    • Guise TA (2000) Molecular mechanisms of osteolytic bone metastases. Cancer 88:2892-2898 (Pubitemid 30413169)
    • (2000) Cancer , vol.88 , Issue.12 SUPPL. , pp. 2892-2898
    • Guise, T.A.1
  • 12
    • 0037025352 scopus 로고    scopus 로고
    • Transforming growth factor-β stimulates parathyroid hormone-related protein and osteolytic metastases via Smad and mitogen-activated protein kinase signaling pathways
    • DOI 10.1074/jbc.M202561200
    • Kakonen SM, Selander KS, Chirgwin JM, Yin JJ, Burns S, Rankin WA, Grubbs BG, Dallas M, Cui Y, Guise TA (2002) Transforming growth factor-beta stimulates parathyroid hormone-related protein and osteolytic metastases via smad and mitogen-activated protein kinase signaling pathways. J Biol Chem 277:24571-24578 (Pubitemid 34951984)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.27 , pp. 24571-24578
    • Kakonen, S.-M.1    Selander, K.S.2    Chirgwin, J.M.3    Yin, J.J.4    Burns, S.5    Rankin, W.A.6    Grubbs, B.G.7    Dallas, M.8    Cui, Y.9    Guise, T.A.10
  • 13
  • 15
    • 33747890209 scopus 로고    scopus 로고
    • The Hedgehog signaling molecule Gli2 induces parathyroid hormone-related peptide expression and osteolysis in metastatic human breast cancer cells
    • DOI 10.1158/0008-5472.CAN-06-0452
    • Sterling JA, Oyajobi BA (2006) The hedgehog signaling molecule gli2 induces parathyroid hormone-related peptide expression and osteolysis in metastatic human breast cancer cells. Cancer Res 66:7548-7553 (Pubitemid 44289210)
    • (2006) Cancer Research , vol.66 , Issue.15 , pp. 7548-7553
    • Sterling, J.A.1    Oyajobi, B.O.2    Grubbs, B.3    Padalecki, S.S.4    Munoz, S.A.5    Gupta, A.6    Story, B.7    Zhao, M.8    Mundy, G.R.9
  • 17
    • 25444473106 scopus 로고    scopus 로고
    • The Runx2 osteogenic transcription factor regulates matrix metalloproteinase 9 in bone metastatic cancer cells and controls cell invasion
    • DOI 10.1128/MCB.25.19.8581-8591.2005
    • Pratap J, Javed A, Languino LR, van Wijnen AJ, Stein JL, Stein GS, Lian JB (2005) The runx2 osteogenic transcription factor regulates matrix metalloproteinase 9 in bone metastatic cancer cells and controls cell invasion. Mol Cell Biol 25:8581-8591 (Pubitemid 41369178)
    • (2005) Molecular and Cellular Biology , vol.25 , Issue.19 , pp. 8581-8591
    • Pratap, J.1    Javed, A.2    Languino, L.R.3    Van Wijnen, A.J.4    Stein, J.L.5    Stein, G.S.6    Lian, J.B.7
  • 20
    • 0042707678 scopus 로고    scopus 로고
    • Interleukin-8 stimulation of osteoclastogenesis and bone resorption is a mechanism for the increased osteolysis of metastatic bone disease
    • DOI 10.1016/S8756-3282(03)00086-3
    • Bendre MS, Montague DC, Peery T, Akel NS, Gaddy D, Suva LJ (2003) Interleukin-8 stimulation of osteoclastogenesis and bone resorption is a mechanism for the increased osteolysis of metastatic bone disease. Bone 33:28-37 (Pubitemid 36952685)
    • (2003) Bone , vol.33 , Issue.1 , pp. 28-37
    • Bendre, M.S.1    Montague, D.C.2    Peery, T.3    Akel, N.S.4    Gaddy, D.5    Suva, L.J.6
  • 21
    • 0036853893 scopus 로고    scopus 로고
    • Guanosine nucleotides inhibit different syndromes of PTHrP excess caused by human cancers in vivo
    • DOI 10.1172/JCI200211936
    • Gallwitz WE, Guise TA (2002) Guanosine nucleotides inhibit different syndromes of pthrp excess caused by human cancers in vivo. J Clin Invest 110:1559-1572 (Pubitemid 35396925)
    • (2002) Journal of Clinical Investigation , vol.110 , Issue.10 , pp. 1559-1572
    • Gallwitz, W.E.1    Guise, T.A.2    Mundy, G.R.3
  • 23
    • 0032717355 scopus 로고    scopus 로고
    • Ablation of the PTHrP gene or the PTH/PTHrP receptor gene leads to distinct abnormalities in bone development
    • Lanske B, Amling M, Neff L, Guiducci J, Baron R, Kronenberg HM (1999) Ablation of the pthrp gene or the pth/pthrp receptor gene leads to distinct abnormalities in bone development. J Clin Invest 104:399-407 (Pubitemid 29534324)
    • (1999) Journal of Clinical Investigation , vol.104 , Issue.4 , pp. 399-407
    • Lanske, B.1    Amling, M.2    Neff, L.3    Guiducci, J.4    Baron, R.5    Kronenberg, H.M.6
  • 24
    • 0031923474 scopus 로고    scopus 로고
    • Rescue of the parathyroid hormone-related protein knockout mouse demonstrates that parathyroid hormone-related protein is essential for mammary gland development
    • Wysolmerski JJ, Philbrick WM, Dunbar ME, Lanske B, Kronenberg H, Broadus AE (1998) Rescue of the parathyroid hormone-related protein knockout mouse demonstrates that parathyroid hormone-related protein is essential for mammary gland development. Development 125:1285-1294 (Pubitemid 28203943)
    • (1998) Development , vol.125 , Issue.7 , pp. 1285-1294
    • Wysolmerski, J.J.1    Philbrick, W.M.2    Dunbar, M.E.3    Lanske, B.4    Kronenberg, H.5    Karaplis, A.6    Broadus, A.E.7
  • 25
    • 0344825793 scopus 로고    scopus 로고
    • Low estrogen and high parathyroid hormone-related peptide levels contribute to accelerated bone resorption and bone loss in lactating mice
    • DOI 10.1210/en.2003-0892
    • VanHouten JN, Wysolmerski JJ (2003) Low estrogen and high parathyroid hormone-related peptide levels contribute to accelerated bone resorption and bone loss in lactating mice. Endocrinology 144:5521-5529 (Pubitemid 37476082)
    • (2003) Endocrinology , vol.144 , Issue.12 , pp. 5521-5529
    • Vanhouten, J.N.1    Wysolmerski, J.J.2
  • 26
    • 0026773422 scopus 로고
    • Parathyroid hormone-related protein in the rat urinary bladder: A smooth muscle relaxant produced locally in response to mechanical stretch
    • Yamamoto M, Harm SC, Grasser WA, Thiede MA (1992) Parathyroid hormone-related protein in the rat urinary bladder: a smooth muscle relaxant produced locally in response to mechanical stretch. Proc Natl Acad Sci USA 89:5326-5330
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 5326-5330
    • Yamamoto, M.1    Harm, S.C.2    Grasser, W.A.3    Thiede, M.A.4
  • 27
    • 0028229537 scopus 로고
    • Synergistic stimulation of parathyroid hormone-related peptide gene expression by mechanical stretch and angiotensin II in rat aortic smooth muscle cells
    • Noda M, Katoh T, Takuwa N, Kumada M, Kurokawa K, Takuwa Y (1994) Synergistic stimulation of parathyroid hormone-related peptide gene expression by mechanical stretch and angiotensin ii in rat aortic smooth muscle cells. J Biol Chem 269:17911-17917 (Pubitemid 24206182)
    • (1994) Journal of Biological Chemistry , vol.269 , Issue.27 , pp. 17911-17917
    • Nodat, M.1    Katoh, T.2    Takuwa, N.3    Kumada, M.4    Kurokawa, K.5    Takuwa, Y.6
  • 28
    • 0028196849 scopus 로고
    • Mechanical stimuli induce vascular parathyroid hormone-related protein gene expression in vivo and in vitro
    • DOI 10.1210/en.134.5.2230
    • Pirola CJ,Wang HM, StrgacichMI, Kamyar A, Cercek B, Forrester JS, Clemens TL, Fagin JA (1994) Mechanical stimuli induce vascular parathyroid hormone-related protein gene expression in vivo and in vitro. Endocrinology 134:2230-2236 (Pubitemid 24142967)
    • (1994) Endocrinology , vol.134 , Issue.5 , pp. 2230-2236
    • Pirola, C.J.1    Wang, H.-M.2    Strgacich, M.I.3    Kamyar, A.4    Cercek, B.5    Forrester, J.S.6    Clemens, T.L.7    Fagin, J.A.8
  • 30
    • 0028294988 scopus 로고
    • Expression of parathyroid hormone-related peptide in relation to perturbations of gastric motility in the rat
    • DOI 10.1210/en.134.4.1936
    • Ito M, Ohtsuru A, Enomoto H, Ozeki S, Nakashima M, Nakayama T, Shichijo K, Sekine I, Yamashita S (1994) Expression of parathyroid hormone-related peptide in relation to perturbations of gastric motility in the rat. Endocrinology 134:1936-1942 (Pubitemid 24110758)
    • (1994) Endocrinology , vol.134 , Issue.4 , pp. 1936-1942
    • Ito, M.1    Ohtsuru, A.2    Enomoto, H.3    Ozeki, S.-I.4    Nakashima, M.5    Nakayama, T.6    Shichijo, K.7    Sekine, I.8    Yamashita, S.9
  • 32
    • 22744432069 scopus 로고    scopus 로고
    • Stretch-induced PTH-related protein gene expression in osteoblasts
    • DOI 10.1359/JBMR.050325
    • Chen X, Macica CM, Ng KW, Broadus AE (2005) Stretchinduced pth-related protein gene expression in osteoblasts. J Bone Miner Res 20:1454-1461 (Pubitemid 41033529)
    • (2005) Journal of Bone and Mineral Research , vol.20 , Issue.8 , pp. 1454-1461
    • Chen, X.1    Macica, C.M.2    Ng, K.W.3    Broadus, A.E.4
  • 33
    • 0028885716 scopus 로고
    • Dual role for the latent transforming growth factor-beta binding protein in storage of latent tgf-beta in the extracellular matrix and as a structural matrix protein
    • Dallas SL, Miyazono K, Skerry TM, Mundy GR, Bonewald LF (1995) Dual role for the latent transforming growth factor-beta binding protein in storage of latent tgf-beta in the extracellular matrix and as a structural matrix protein. J Cell Biol 131:539-549
    • (1995) J Cell Biol , vol.131 , pp. 539-549
    • Dallas, S.L.1    Miyazono, K.2    Skerry, T.M.3    Mundy, G.R.4    Bonewald, L.F.5
  • 34
    • 0141499870 scopus 로고    scopus 로고
    • Bone matrix proteins: Their function, regulation, and relationship to osteoporosis
    • Young MF (2003) Bone matrix proteins: their function, regulation, and relationship to osteoporosis. Osteoporos Int 14(Suppl 3):S35-S42
    • (2003) Osteoporos Int , vol.14 , Issue.SUPPL. 3
    • Young, M.F.1
  • 35
    • 0034056341 scopus 로고    scopus 로고
    • Cellular and molecular basis of preferential metastasis of breast cancer to bone
    • Yoneda T (2000) Cellular and molecular basis of preferential metastasis of breast cancer to bone. J Orthop Sci 5:75-81 (Pubitemid 30133795)
    • (2000) Journal of Orthopaedic Science , vol.5 , Issue.1 , pp. 75-81
    • Yoneda, T.1
  • 36
    • 0031445986 scopus 로고    scopus 로고
    • Attachment characteristics and involvement of integrins in adhesion of breast cancer cell lines to extracellular bone matrix components
    • van der P, Vloedgraven H, Papapoulos S, Lowick C, Grzesik W, Kerr J, Robey PG (1997) Attachment characteristics and involvement of integrins in adhesion of breast cancer cell lines to extracellular bone matrix components. Lab Invest 77:665-675 (Pubitemid 28018788)
    • (1997) Laboratory Investigation , vol.77 , Issue.6 , pp. 665-675
    • Van Der Pluijm, G.1    Vloedgraven, H.2    Papapoulos, S.3    Lowik, C.4    Grzesik, W.5    Kerr, J.6    Robey, P.G.7
  • 37
    • 0029937529 scopus 로고    scopus 로고
    • Integrin alpha v beta 3 expression by bone-residing breast cancer metastases
    • Liapis H, Flath A, Kitazawa S (1996) Integrin alpha v beta 3 expression by bone-residing breast cancer metastases. Diagn Mol Pathol 5:127-135
    • (1996) Diagn Mol Pathol , vol.5 , pp. 127-135
    • Liapis, H.1    Flath, A.2    Kitazawa, S.3
  • 38
    • 34548680519 scopus 로고    scopus 로고
    • Prostate cancer specific integrin αvβ3 modulates bone metastatic growth and tissue remodeling
    • DOI 10.1038/sj.onc.1210429, PII 1210429
    • McCabe NP, De S, Vasanji A, Brainard J, Byzova TV (2007) Prostate cancer specific integrin alphavbeta3 modulates bone metastatic growth and tissue remodeling. Oncogene 26:6238-6243 (Pubitemid 47414368)
    • (2007) Oncogene , vol.26 , Issue.42 , pp. 6238-6243
    • McCabe, N.P.1    De, S.2    Vasanji, A.3    Brainard, J.4    Byzova, T.V.5
  • 39
    • 0034000614 scopus 로고    scopus 로고
    • An antisense oligonucleotide targeting the αV integrin gene inhibits adhesion and induces apoptosis in breast cancer cells
    • DOI 10.1016/S0959-8049(99)00275-0, PII S0959804999002750
    • Townsend PA, Villanova I, Uhlmann E, Peyman A, Knolle J, Baron R, Teti A, Horton MA (2000) An antisense oligonucleotide targeting the alphav integrin gene inhibits adhesion and induces apoptosis in breast cancer cells. Eur J Cancer 36:397-409 (Pubitemid 30116738)
    • (2000) European Journal of Cancer , vol.36 , Issue.3 , pp. 397-409
    • Townsend, P.A.1    Villanova, I.2    Uhlmann, E.3    Peyman, A.4    Knolle, J.5    Baron, R.6    Teti, A.7    Horton, M.A.8
  • 41
    • 78650304364 scopus 로고    scopus 로고
    • Integrins and bone metastasis: Integrating tumor cell and stromal cell interactions
    • Schneider JG, Amend SR, Weilbaecher KN (2011) Integrins and bone metastasis: integrating tumor cell and stromal cell interactions. Bone 48:54-65
    • (2011) Bone , vol.48 , pp. 54-65
    • Schneider, J.G.1    Amend, S.R.2    Weilbaecher, K.N.3
  • 46
    • 79957521370 scopus 로고    scopus 로고
    • Bone structural components regulating sites of tumor metastasis
    • Sterling JA, Guelcher SA (2011) Bone structural components regulating sites of tumor metastasis. Curr Osteoporos Rep
    • (2011) Curr Osteoporos Rep
    • Sterling, J.A.1    Guelcher, S.A.2
  • 49
    • 0037178784 scopus 로고    scopus 로고
    • Exploring the neighborhood: Adhesion-coupled cell mechanotransducers
    • Geiger B, Bershaksky A (2002) Exploring the neighborhood: adhesion-coupled cell mechanotransducers. Cell 110:139-143
    • (2002) Cell , vol.110 , pp. 139-143
    • Geiger, B.1    Bershaksky, A.2
  • 50
    • 77955580383 scopus 로고    scopus 로고
    • Stretchy proteins on stretchy substrates: The important elements of integrinmediated rigidity sensing
    • Moore SW, Roca-Cusachs P, Sheetz MP (2010) Stretchy proteins on stretchy substrates: the important elements of integrinmediated rigidity sensing. Dev Cell 19:194-206
    • (2010) Dev Cell , vol.19 , pp. 194-206
    • Moore, S.W.1    Roca-Cusachs, P.2    Sheetz, M.P.3
  • 52
    • 22944454223 scopus 로고    scopus 로고
    • The tension mounts: Mechanics meets morphogenesis and malignancy
    • DOI 10.1007/s10911-004-1404-x
    • Paszek MJ, Weaver VM (2004) The tension mounts: mechanics meets morphogenesis and malignancy. J Mammary Gland Biol Neoplasia 9:325-342 (Pubitemid 41149140)
    • (2004) Journal of Mammary Gland Biology and Neoplasia , vol.9 , Issue.4 , pp. 325-342
    • Paszek, M.J.1    Weaver, V.M.2
  • 53
    • 24944436269 scopus 로고    scopus 로고
    • Cell tension, matrix mechanics, and cancer development
    • DOI 10.1016/j.ccr.2005.08.009, PII S1535610805002679
    • Huang SJ, Ingber DE (2005) Cell tension, matrix mechanics, and cancer development. Cancer Cell 8:175-176 (Pubitemid 41317587)
    • (2005) Cancer Cell , vol.8 , Issue.3 , pp. 175-176
    • Huang, S.1    Ingber, D.E.2
  • 54
    • 33947377168 scopus 로고    scopus 로고
    • Effect of mechanical loading on insulin-like growth factor-I gene expression in rat tibia
    • DOI 10.1677/joe.1.06880
    • Reijnders CM, Bravenboer N, Tromp AM, Blankenstein MA, Lips P (2007) Effect of mechanical loading on insulin-like growth factor-i gene expression in rat tibia. J Endocrinol 192:131-140 (Pubitemid 46444403)
    • (2007) Journal of Endocrinology , vol.192 , Issue.1 , pp. 131-140
    • Reijnders, C.M.A.1    Bravenboer, N.2    Tromp, A.M.3    Blankenstein, M.A.4    Lips, P.5
  • 55
    • 78650926548 scopus 로고    scopus 로고
    • Gene expression patterns in bone following mechanical loading
    • Mantila Roosa SM, Liu Y, Turner CH (2011) Gene expression patterns in bone following mechanical loading. J Bone Miner Res 26:100-112
    • (2011) J Bone Miner Res , vol.26 , pp. 100-112
    • Mantila Roosa, S.M.1    Liu, Y.2    Turner, C.H.3
  • 56
    • 0033990244 scopus 로고    scopus 로고
    • Micropipette aspiration of living cells
    • Hochmuth RM (2000) Micropipette aspiration of living cells. J Biomech 33:15-22
    • (2000) J Biomech , vol.33 , pp. 15-22
    • Hochmuth, R.M.1
  • 57
    • 33646155963 scopus 로고    scopus 로고
    • Rigidity sensing at the leading edge through alphavbeta3 integrins and rptpalpha
    • Jiang G, Huang AH, Cai Y, Tanase M, Sheetz MP (2006) Rigidity sensing at the leading edge through alphavbeta3 integrins and rptpalpha. Biophys J 90:1804-1809
    • (2006) Biophys J , vol.90 , pp. 1804-1809
    • Jiang, G.1    Huang, A.H.2    Cai, Y.3    Tanase, M.4    Sheetz, M.P.5
  • 58
    • 28444491145 scopus 로고    scopus 로고
    • Is the mechanical activity of epithelial cells controlled by deformations or forces?
    • DOI 10.1529/biophysj.105.071217
    • Saez A, Buguin A, Silberzan P, Ladoux B (2005) Is the mechanical activity of epithelial cells controlled by deformations or forces? Biophys J 89:L52-L54 (Pubitemid 41725585)
    • (2005) Biophysical Journal , vol.89 , Issue.6
    • Saez, A.1    Buguin, A.2    Silberzan, P.3    Ladoux, B.4
  • 59
    • 27944497333 scopus 로고    scopus 로고
    • Tissue cells feel and respond to the stiffness of their substrate
    • DOI 10.1126/science.1116995
    • Discher DE, Janmey P, Wang YL (2005) Tissue cells feel and respond to the stiffness of their substrate. Science 310:1139-1143 (Pubitemid 41681732)
    • (2005) Science , vol.310 , Issue.5751 , pp. 1139-1143
    • Discher, D.E.1    Janmey, P.2    Wang, Y.-L.3
  • 61
    • 72949119294 scopus 로고    scopus 로고
    • Matrix mechanics and receptorligand interactions in cell adhesion
    • Harjanto D, Zaman MH (2010) Matrix mechanics and receptorligand interactions in cell adhesion. Org Biomol Chem 8:299-304
    • (2010) Org Biomol Chem , vol.8 , pp. 299-304
    • Harjanto, D.1    Zaman, M.H.2
  • 62
    • 34247891506 scopus 로고    scopus 로고
    • Structural basis of integrin regulation and signaling
    • DOI 10.1146/annurev.immunol.25.022106.141618
    • Luo BH, Carman CV, Springer TA (2007) Structural basis of integrin regulation and signaling. Annu Rev Immunol 25:619-647 (Pubitemid 46697919)
    • (2007) Annual Review of Immunology , vol.25 , pp. 619-647
    • Luo, B.-H.1    Carman, C.V.2    Springer, T.A.3
  • 65
    • 0027329003 scopus 로고
    • Receptor protein tyrosine phosphatase α activates pp60(c-src) and is involved in neuronal differentiation
    • den Hertog J, Pals CE, Peppelenbosch MP, Tertoolen LG, de Laat SW, Kruijer W (1993) Receptor protein tyrosine phosphatase alpha activates pp 60c-src and is involved in neuronal differentiation. EMBO J 12:3789-3798 (Pubitemid 23282755)
    • (1993) EMBO Journal , vol.12 , Issue.10 , pp. 3789-3798
    • Den Hertog, J.1    Pals, C.E.G.M.2    Peppelenbosch, M.P.3    Tertoolen, L.G.J.4    De Laat, S.W.5    Kruijer, W.6
  • 67
    • 0034161405 scopus 로고    scopus 로고
    • A phosphotyrosine displacement mechanism for activation of Src by PTPα
    • Zheng XM, Resnick RJ, Shalloway D (2000) A phosphotyrosine displacement mechanism for activation of src by ptpalpha. EMBO J 19:964-978 (Pubitemid 30119822)
    • (2000) EMBO Journal , vol.19 , Issue.5 , pp. 964-978
    • Zheng, X.-M.1    Resnick, R.J.2    Shalloway, D.3
  • 68
    • 0032570809 scopus 로고    scopus 로고
    • Mechanical stressing of integrin receptors induces enhanced tyrosine phosphorylation of cytoskeletally anchored proteins
    • DOI 10.1074/jbc.273.9.5081
    • Schmidt C, Pommerenke H, Durr F, Nebe B, Rychly J (1998) Mechanical stressing of integrin receptors induces enhanced tyrosine phosphorylation of cytoskeletally anchored proteins. J Biol Chem 273:5081-5085 (Pubitemid 28108667)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.9 , pp. 5081-5085
    • Schmidt, C.1    Pommerenke, H.2    Durr, F.3    Nebe, B.4    Rychly, J.5
  • 69
    • 84856419673 scopus 로고    scopus 로고
    • Transforming growth factor beta stimulates parathyroid hormone related protein an dosteolytic metastases via smad and mapk signaling pathways
    • Kakonenea SM (2005) Transforming growth factor beta stimulates parathyroid hormone related protein an dosteolytic metastases via smad and mapk signaling pathways. J Biol Chem 227
    • (2005) J Biol Chem , vol.227
    • Kakonenea, S.M.1
  • 70
    • 0027172919 scopus 로고
    • Mechanotransduction across the cell surface and through the cytoskeleton
    • Wang N, Butler JP, Ingber DE (1993) Mechanotransduction across the cell surface and through the cytoskeleton. Science 260:1124-1127 (Pubitemid 23186787)
    • (1993) Science , vol.260 , Issue.5111 , pp. 1124-1127
    • Wang, N.1    Butler, J.P.2    Ingber, D.E.3
  • 71
    • 0037175402 scopus 로고    scopus 로고
    • The relationship between force and focal complex development
    • Galbraith CG, Yamada KM, Sheetz MP (2002) The relationship between force and focal complex development. J Cell Biol 159:695-705
    • (2002) J Cell Biol , vol.159 , pp. 695-705
    • Galbraith, C.G.1    Yamada, K.M.2    Sheetz, M.P.3
  • 72
    • 0242361579 scopus 로고    scopus 로고
    • Talin1 is critical for force-dependent reinforcement of initial integrin-cytoskeleton bonds but not tyrosine kinase activation
    • DOI 10.1083/jcb.200302001
    • Giannone G, Jiang G, Sutton DH, Critchley DR, Sheetz MP (2003) Talin1 is critical for force-dependent reinforcement of initial integrin-cytoskeleton bonds but not tyrosine kinase activation. J Cell Biol 163:409-419 (Pubitemid 37363140)
    • (2003) Journal of Cell Biology , vol.163 , Issue.2 , pp. 409-419
    • Giannone, G.1    Jiang, G.2    Sutton, D.H.3    Critchley, D.R.4    Sheetz, M.P.5
  • 74
    • 0030994017 scopus 로고    scopus 로고
    • Extracellular matrix rigidity causes strengthening of integrin- cytoskeleton linkages
    • Choquet D, Felsenfeld DP, Sheetz MP (1997) Extracellular matrix rigidity causes strengthening of integrin-cytoskeleton linkages. Cell 88:39-48 (Pubitemid 27180329)
    • (1997) Cell , vol.88 , Issue.1 , pp. 39-48
    • Choquet, D.1    Felsenfeld, D.P.2    Sheetz, M.P.3
  • 75
    • 34250625176 scopus 로고    scopus 로고
    • Force activates smooth muscle α-actin promoter activity through the Rho signaling pathway
    • DOI 10.1242/jcs.001586
    • Zhao XH, Laschinger C, Arora P, Szaszi K, Kapus A, McCulloch CA (2007) Force activates smooth muscle alpha-actin promoter activity through the rho signaling pathway. J Cell Sci 120:1801-1809 (Pubitemid 46930418)
    • (2007) Journal of Cell Science , vol.120 , Issue.10 , pp. 1801-1809
    • Zhao, X.-H.1    Laschinger, C.2    Arora, P.3    Szaszi, K.4    Kapus, A.5    McCulloch, C.A.6
  • 79
    • 33747152561 scopus 로고    scopus 로고
    • Matrix Elasticity Directs Stem Cell Lineage Specification
    • DOI 10.1016/j.cell.2006.06.044, PII S0092867406009615
    • Engler AJ, Sen S, Sweeney HL, Discher DE (2006) Matrix elasticity directs stem cell lineage specification. Cell 126:677-689 (Pubitemid 44233625)
    • (2006) Cell , vol.126 , Issue.4 , pp. 677-689
    • Engler, A.J.1    Sen, S.2    Sweeney, H.L.3    Discher, D.E.4
  • 81
    • 77953651459 scopus 로고    scopus 로고
    • The dependence of mg63 osteoblast responses to (meth)acrylate-based networks on chemical structure and stiffness
    • Smith KE, Hyzy SL, Sunwoo M, Gall KA, Schwartz Z, Boyan BD (2010) The dependence of mg63 osteoblast responses to (meth)acrylate-based networks on chemical structure and stiffness. Biomaterials 31:6131-6141
    • (2010) Biomaterials , vol.31 , pp. 6131-6141
    • Smith, K.E.1    Hyzy, S.L.2    Sunwoo, M.3    Gall, K.A.4    Schwartz, Z.5    Boyan, B.D.6
  • 82
    • 65949097929 scopus 로고    scopus 로고
    • Ecm compliance regulates osteogenesis by influencing mapk signaling downstream of rhoa and rock
    • Khatiwala CB, Kim PD, Peyton SR, Putnam AJ (2009) Ecm compliance regulates osteogenesis by influencing mapk signaling downstream of rhoa and rock. J Bone Miner Res 24:886-898
    • (2009) J Bone Miner Res , vol.24 , pp. 886-898
    • Khatiwala, C.B.1    Kim, P.D.2    Peyton, S.R.3    Putnam, A.J.4
  • 84
    • 39649087588 scopus 로고    scopus 로고
    • Mechanical properties, biocompatibility, and biodegradation of polyurethane networks from lysine polyisocyanates
    • Synthesis
    • Guelcher SA, Dumas J, Srinivasan A, Didier JE, Hollinger JO (2008) Synthesis, mechanical properties, biocompatibility, and biodegradation of polyurethane networks from lysine polyisocyanates. Biomaterials 29:1762-1775
    • (2008) Biomaterials , vol.29 , pp. 1762-1775
    • Guelcher, S.A.1    Dumas, J.2    Srinivasan, A.3    Didier, J.E.4    Hollinger, J.O.5
  • 87
    • 79551484683 scopus 로고    scopus 로고
    • Influence of substrate stiffness on cell-substrate interfacial adhesion and spreading: A mechano-chemical coupling model
    • Huang JH, Peng XL, Xiong CY, Fang J (2011) Influence of substrate stiffness on cell-substrate interfacial adhesion and spreading: a mechano-chemical coupling model. J Coll Interfac Sci 355:503-508
    • (2011) J Coll Interfac Sci , vol.355 , pp. 503-508
    • Huang, J.H.1    Peng, X.L.2    Xiong, C.Y.3    Fang, J.4
  • 88
    • 0018101150 scopus 로고
    • Models for the specific adhesion of cells to cells
    • Bell GI (1978) Models for the specific adhesion of cells to cells. Science 200:618-627
    • (1978) Science , vol.200 , pp. 618-627
    • Bell, G.I.1
  • 90
    • 72949119124 scopus 로고    scopus 로고
    • Integrins in cancer: Biological implications and therapeutic opportunities
    • Desgrosellier JS, Cheresh DA Integrins in cancer: biological implications and therapeutic opportunities. Nat Rev Cancer 10:9-22
    • Nat Rev Cancer , vol.10 , pp. 9-22
    • Desgrosellier, J.S.1    Cheresh, D.A.2
  • 92
    • 33747086130 scopus 로고    scopus 로고
    • Beta3 integrin and src facilitate transforming growth factor-beta mediated induction of epithelial-mesenchymal transition in mammary epithelial cells
    • Galliher AJ, Schiemann WP (2006) Beta3 integrin and src facilitate transforming growth factor-beta mediated induction of epithelial-mesenchymal transition in mammary epithelial cells. Breast Canc Res 8:R42
    • (2006) Breast Canc Res , vol.8
    • Galliher, A.J.1    Schiemann, W.P.2
  • 93
    • 33644967727 scopus 로고    scopus 로고
    • Cellular adaptation to mechanical stress: Role of integrins, rho, cytoskeletal tension and mechanosensitive ion channels
    • Matthews BD, Overby DR, Mannix R, Ingber DE (2006) Cellular adaptation to mechanical stress: role of integrins, rho, cytoskeletal tension and mechanosensitive ion channels. J Cell Sci 119:508-518
    • (2006) J Cell Sci , vol.119 , pp. 508-518
    • Matthews, B.D.1    Overby, D.R.2    Mannix, R.3    Ingber, D.E.4
  • 95
    • 33751335857 scopus 로고    scopus 로고
    • Force Sensing by Mechanical Extension of the Src Family Kinase Substrate p130Cas
    • DOI 10.1016/j.cell.2006.09.044, PII S009286740601405X
    • Sawada Y, Tamada M, Dubin-Thaler BJ, Cherniavskaya O, Sakai R, Tanaka S, Sheetz MP (2006) Force sensing by mechanical extension of the src family kinase substrate p130cas. Cell 127:1015-1026 (Pubitemid 44803062)
    • (2006) Cell , vol.127 , Issue.5 , pp. 1015-1026
    • Sawada, Y.1    Tamada, M.2    Dubin-Thaler, B.J.3    Cherniavskaya, O.4    Sakai, R.5    Tanaka, S.6    Sheetz, M.P.7
  • 96
    • 66849101632 scopus 로고    scopus 로고
    • Adhesion signaling - Crosstalk between integrins, src and rho
    • Huveneers S, Danen EH (2009) Adhesion signaling - crosstalk between integrins, src and rho. J Cell Sci 122:1059-1069
    • (2009) J Cell Sci , vol.122 , pp. 1059-1069
    • Huveneers, S.1    Danen, E.H.2
  • 97
    • 2942722790 scopus 로고    scopus 로고
    • A small molecule antagonist of the alphavbeta3 integrin suppresses mda-mb-435 skeletal metastasis
    • Harms ea (2004) A small molecule antagonist of the alphavbeta3 integrin suppresses mda-mb-435 skeletal metastasis. Clin Exp Met 21:119-128
    • (2004) Clin Exp Met , vol.21 , pp. 119-128
    • Harms, E.A.1
  • 99
    • 0041513490 scopus 로고    scopus 로고
    • C-src tyrosine kinase activity is associated with tumor colonization in bone and lung in an animal model of human breast cancer metastasis
    • Myoui ANR, Williams PJ, Hiraga T, Tamura D, Michigami T et al (2003) C-src tyrosine kinase activity is associated with tumor colonization in bone and lung in an animal model of human breast cancer metastasis. Cancer Res 63:5028-5033 (Pubitemid 37022641)
    • (2003) Cancer Research , vol.63 , Issue.16 , pp. 5028-5033
    • Myoui, A.1    Nishimura, R.2    Williams, P.J.3    Hiraga, T.4    Tamura, D.5    Michigami, T.6    Mundy, G.R.7    Yoneda, T.8
  • 100
    • 0024095296 scopus 로고
    • Fibronectin receptor exhibits high lateral mobility in embryonic locomoting cells but is immobile in focal contacts and fibrillar streaks in stationary cells
    • Duband JL, Nuckolls GH, Ishihara A, Hasegawa T, Yamada KM, Thiery JP, Jacobson K (1988) Fibronectin receptor exhibits high lateral mobility in embryonic locomoting cells but is immobile in focal contacts and fibrillar streaks in stationary cells. J Cell Biol 107:1385-1396
    • (1988) J Cell Biol , vol.107 , pp. 1385-1396
    • Duband, J.L.1    Nuckolls, G.H.2    Ishihara, A.3    Hasegawa, T.4    Yamada, K.M.5    Thiery, J.P.6    Jacobson, K.7
  • 101
    • 0033175564 scopus 로고    scopus 로고
    • Selective regulation of integrin-cytoskeleton interactions by the tyrosine kinase Src
    • Felsenfeld DP, Schwartzberg PL, Venegas A, Tse R, Sheetz MP (1999) Selective regulation of integrin-cytoskeleton interactions by the tyrosine kinase src. Nat Cell Biol 1:200-206 (Pubitemid 129500938)
    • (1999) Nature Cell Biology , vol.1 , Issue.4 , pp. 200-206
    • Felsenfeld, D.P.1    Schwartzberg, P.L.2    Venegas, A.3    Tse, R.4    Sheetz, M.P.5
  • 102
    • 51049100594 scopus 로고    scopus 로고
    • Talin depletion reveals independence of initial cell spreading from integrin activation and traction
    • Zhang X, Jiang G, Cai Y, Monkley SJ, Critchley DR, Sheetz MP (2008) Talin depletion reveals independence of initial cell spreading from integrin activation and traction. Nat Cell Biol 10:1062-1068
    • (2008) Nat Cell Biol , vol.10 , pp. 1062-1068
    • Zhang, X.1    Jiang, G.2    Cai, Y.3    Monkley, S.J.4    Critchley, D.R.5    Sheetz, M.P.6
  • 103
    • 33747086130 scopus 로고    scopus 로고
    • Beta3 integrin and src facilitate transforming growth factor beta mediated induction of epithelialmesenchumal transition in mammary epithelial cells
    • Galliher AJSW (2006) Beta3 integrin and src facilitate transforming growth factor beta mediated induction of epithelialmesenchumal transition in mammary epithelial cells. Breast Cancer Res 8:R42
    • (2006) Breast Cancer Res , vol.8
    • Ajsw, G.1
  • 105
    • 0032721665 scopus 로고    scopus 로고
    • Role of integrins in cancer: Survey of expression patterns
    • Mizejewski GJ (1999) Role of integrins in cancer: survey of expression patterns. Proc Soc Exp Biol Med 222:124-138
    • (1999) Proc Soc Exp Biol Med , vol.222 , pp. 124-138
    • Mizejewski, G.J.1
  • 106
    • 77952307943 scopus 로고    scopus 로고
    • Evolving data about subtrochanteric fractures and bisphosphonates
    • Shane E Evolving data about subtrochanteric fractures and bisphosphonates. N Engl J Med 362:1825-1827
    • N Engl J Med , vol.362 , pp. 1825-1827
    • Shane, E.1
  • 109
    • 33646079184 scopus 로고    scopus 로고
    • Inhibition of RANKL as a treatment for osteoporosis: Preclinical and early clinical studies
    • DOI 10.1007/s11914-006-0012-7
    • McClung MR (2006) Inhibition of rankl as a treatment for osteoporosis: preclinical and early clinical studies. Curr Osteoporos Rep 4:28-33 (Pubitemid 44623945)
    • (2006) Current Osteoporosis Reports , vol.4 , Issue.1 , pp. 28-33
    • McClung, M.R.1
  • 116
    • 67349091089 scopus 로고    scopus 로고
    • Transforming growth factorbeta signaling: Emerging stem cell target in metastatic breast cancer?
    • Tan AR, Alexe G, Reiss M (2009) Transforming growth factorbeta signaling: emerging stem cell target in metastatic breast cancer? Breast Canc Res Treat 115:453-495
    • (2009) Breast Canc Res Treat , vol.115 , pp. 453-495
    • Tan, A.R.1    Alexe, G.2    Reiss, M.3
  • 117
    • 70350724182 scopus 로고    scopus 로고
    • Rhoa/rho-kinase signaling: A therapeutic target in pulmonary hypertension
    • Barman SA, Zhu S, White RE (2009) Rhoa/rho-kinase signaling: a therapeutic target in pulmonary hypertension. Vasc Health Risk Manag 5:663-671
    • (2009) Vasc Health Risk Manag , vol.5 , pp. 663-671
    • Barman, S.A.1    Zhu, S.2    White, R.E.3
  • 118
    • 41749091574 scopus 로고    scopus 로고
    • Applications for rock kinase inhibition
    • Olson MF (2008) Applications for rock kinase inhibition. Curr Opin Cell Biol 20:242-248
    • (2008) Curr Opin Cell Biol , vol.20 , pp. 242-248
    • Olson, M.F.1
  • 119
    • 33645072205 scopus 로고    scopus 로고
    • Treatment for advanced tumors: Src reclaims center stage
    • Summy JM, Gallick GE (2006) Treatment for advanced tumors: Src reclaims center stage. Clin Canc Res 12:1398-1401
    • (2006) Clin Canc Res , vol.12 , pp. 1398-1401
    • Summy, J.M.1    Gallick, G.E.2
  • 121
    • 72949119124 scopus 로고    scopus 로고
    • Integrins in cancer: Biological implications and therapeutic opportunities
    • Desgrosellier JSCD (2010) Integrins in cancer: biological implications and therapeutic opportunities. Nat Rev Cancer 10:9-22
    • (2010) Nat Rev Cancer , vol.10 , pp. 9-22
    • Jscd, D.1
  • 123
  • 128
    • 34248584887 scopus 로고    scopus 로고
    • 284 in TGF-β type II receptor and regulates TGF-β stimulation of p38 MAPK during breast cancer cell proliferation and invasion
    • DOI 10.1158/0008-5472.CAN-06-3851
    • Galliher AJ, Schiemann WP (2007) Src phosphorylates tyr284 in tgf-beta type ii receptor and regulates tgf-beta stimulation of p38 mapk during breast cancer cell proliferation and invasion. Cancer Res 67:3752-3758 (Pubitemid 46762161)
    • (2007) Cancer Research , vol.67 , Issue.8 , pp. 3752-3758
    • Galliher, A.J.1    Schiemann, W.P.2


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