Stretch-induced PTH-related protein gene expression in osteoblasts

Journal of Bone and Mineral Research

Volumn 20, Issue 8, 2005, Pages 1454-1461

  Chen, Xuesong ^a   Macica, Carolyn M ^a   Ng, Kong Wah ^b   Broadus, Arthur E ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b ST VINCENT S HOSPITAL   (Australia)

Author keywords

Anabolic effect; Ion channels; Mechanical loading; Osteoblast; PTH related protein

Indexed keywords

CALCIUM; CALCIUM CHANNEL L TYPE; CATION; GADOLINIUM; GENE PRODUCT; HYPOTONIC SOLUTION; NIFEDIPINE; PARATHYROID HORMONE RELATED PROTEIN;

ANIMAL CELL; ARTICLE; BIOMECHANICS; BONE MASS; BONE STRUCTURE; CELL DIFFERENTIATION; CONTROLLED STUDY; GENE; GENE FUNCTION; MECHANOTRANSDUCTION; NONHUMAN; OSTEOBLAST; POLYMERASE CHAIN REACTION; PTHRP GENE; RAT; TREK2 GENE; WEIGHT BEARING;

EID: 22744432069     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/jbmr.2005.20.8.1454     Document Type: Article

References (34)

1. Ahlborg HG, Johnell O, Turner CH, Rannevik CH, Karlsson MK 2003 Bone loss and bone size after menopause. N Engl J Med 349:327-334.
2. Seeman E 2003 Periosteal bone formation-a neglected determinant of bone strength. N Engl J Med 349:320-323.
3. Broadus AE, Mangin M, Ikeda K, Insogna KL, Weir EC, Burtis WJ, Stewart AF 1988 Humoral hypercalcemia of cancer. Identification of a novel parathyroid hormone-like peptide. N Engl J Med 319:556-563.
4. Strewler GJ 2000 The physiology of parathyroid hormone-related protein. N Engl J Med 342:177-185.
5. Horwitz MJ, Tedesco MB, Gundberg C, Garcia-Ocana A, Stewart AF 2003 Short-term, high-dose parathyroid hormone-related protein as a skeletal anabolic agent for the treatment of postmenopausal osteoporosis. J Clin Endocrinol Metab 88:569-575.
6. Suda N, Gillespie MT, Traianedes K, Zhou H, Ho PW, Hards DK, Allan EH, Martin TJ, Moseley JM 1996 Expression of parathyroid hormone-related protein in cells of osteoblast lineage. J Cell Physiol 166:94-104.
7. Liu F, Malaval L, Aubin JE 2003 Global amplification polymerase chain reaction reveals novel transitional stages during osteoprogenitor differentiation. J Cell Sci 116:1787-1796.
8. Candeliere GA, Liu F, Aubin JE 2001 Individual osteoblasts in the developing calvaria express different gene repertoires. Bone 28:351-361.
9. Kartsogiannis V, Moseley J, McKelvie B, Chou ST, Hards DK, Ng KW, Martin TJ, Zhou H 1997 Temporal expression of PTHrP during endochondral bone formation in mouse and intramembranous bone formation in an in vivo rabbit model. Bone 21:385-392.
10. Miao D, He B, Tong XK, Goltzman D, Karaplis AC 2002 Conditional knockout of PTHrP in osteoblasts leads to premature osteoporosis. J Bone Miner Res 17:S1;S138.
11. Turner CH, Robling AG, Duncan RL, Burr DB 2002 Do bone cells behave like a neuronal network? Calcif Tissue Int 70:435-442.
12. Forwood MR, Owan I, Takano Y, Turner CH 1996 Increased bone formation in rat tibiae after a single short period of dynamic loading in vivo. Am J Physiol 270:E419-E423.
13. Chow JW, Wilson AJ, Chambers TJ, Fox SW 1998 Mechanical loading stimulates bone formation by reactivation of bone lining cells in 13-week-old rats. J Bone Miner Res 13:1760-1767.
14. Dobnig H, Turner RT 1995 Evidence that intermittent treatment with parathyroid hormone increases bone formation in adult rats by activation of bone lining cells. Endocrinology 136:3632-3638.
15. Miyauchi A, Notoya K, Mikuni-Takagaki Y, Takagi Y, Goto M, Miki Y, Takano-Yamamoto T, Jinnai K, Takahashi K, Kumegawa M, Chihara K, Fujita T 2000 Parathyroid hormone-activated volume-sensitive calcium influx pathways in mechanically loaded osteocytes. J Biol Chem 275:3335-3342.
16. Duncan RL, Kizer N, Barry ELR, Friedman PA, Hruska KA 1996 Antisense oligodeoxynucleotide inhibition of a swelling-activated cation channel in osteoblast-like osteosarcoma cells. Proc Natl Acad Sci USA 93:1864-1869.
17. Duncan RL, Hruska KA 1994 Chronic, intermittent loading alters mechanosensitive channel characteristics in osteoblast-like cells. Am J Physiol 267:F909-F916.
18. Kizer N, Harter L, Hruska K, Alvarez U, Duncan R 1999 Volume regulatory decrease in UMR-106.01 cells is mediated by specific alphal subunits of L-type calcium channels. Cell Biochem Biophys 31:65-79.
19. Patel AJ, Lazdunski M, Honore E 2001 Lipid and mechanogated 2P domain K(+) channels. Curr Opin Cell Biol 13:422-428.
20. Daifotis AG, Weir EC, Dreyer BE, Broadus AE 1992 Stretch-induced parathyroid hormone-related peptide gene expression in the rat uterus. J Biol Chem 267:23455-23458.
21. Zhou H, Hammonds RG Jr, Findlay DM, Fuller PJ, Martin TJ, Ng KW 1991 Retinoic acid modulation of mRNA levels in malignant, nontransformed, and immortalized osteoblasts. J Bone Miner Res 6:767-777.
22. Yang KH, DePapp AE, Soifer NE, Dreyer BE, Wu TL, Porter SE, Bellantoni M, Burtis WJ, Insogna KL, Broadus AE 1994 Parathyroid hormone-related protein: Evidence for isoform-and tissue-specific posttranslational processing. Biochemistry 33:7460-7469.
23. Nilius B, Droogmans G 2003 Amazing chloride channels: An overview. Acta Physiol Scand 177:119-147.
24. Mikuni-Takagaki Y, Suzuki Y, Kawase T, Saito S 1996 Distinct responses of different populations of bone cells to mechanical stress. Endocrinology 137:2028-2035.
25. Kato Y, Boskey A, Spevak L, Dallas M, Hori M, Bonewald LF 2001 Establishment of an osteoid preosteocyte-like cell MLO-A5 that spontaneously mineralizes in culture. J Bone Miner Res 16:1622-1633.
26. Sorkin AM, Dee KC, Knothe Tate ML 2004 "Culture shock" from the bone cell's perspective: Emulating physiological conditions for mechanobiological investigations. Am J Physiol Cell Physiol 287:C1527-C1536.
27. Rubin CT, Lanyon LE 1984 Dynamic strain similarity in vertebrates: an alternative to allometric limb bone scaling. J Theor Biol 107:321-327.
28. Brand RA, Stanford CM, Nicolella DP 2001 Primary adult human bone cells do not respond to tissue (continuum) level strains. J Orthop Sci 6:295-301.
29. Lo C, Ferrier J, Tenenbaum HC, McCulloch CAG 1995 Regulation of cell volume and intracellular pH in hyposmotically swollen rat osteosarcoma cells. Biochem Cell Biol 73:535-544.
30. Philbrick WM, Wysolmerski JJ, Galbraith S. Holt E, Orloff JJ, Yang KH, Vasavada RC, Weir EC, Broadus AE, Stewart AF 1996 Defining the roles of parathyroid hormone-related protein in normal physiology. Physiol Rev 76:127-173.
31. Holt EH, Lu C, Dreyer BE, Dannies PS, Broadus AE 1994 Regulation of parathyroid hormone-related peptide gene expression by estrogen in GH4C1 rat pituitary cells has the pattern of a primary response gene. J Neurochem 62:1239-1246.
32. Macica CM, Broadus AE 2003 PTHrP regulates cerebral blood flow and is neuroprotective. Am J Physiol Regul Integr Comp Physiol 284:R1019-R1020.
33. Deal C 2004 The use of intermittent human parathyroid hormone as a treatment for osteoporosis. Curr Rheumatol Rep 6:49-58.
34. Speake T, Elliott AC 1998 Modulation of calcium signals by intracellular pH in isolated rat pancreatic acinar cells. J Physiol 506:415-430.