Integrin expression in breast cancer cytology: A novel predictor of axillary metastasis

European Journal of Surgical Oncology

Volumn 22, Issue 3, 1996, Pages 254-258

  Gui, G P H ^a   Wells, C A ^a   Yeomans, P ^a   Jordan, S E ^a   Vinson, G P ^b   Carpenter, R ^a,c  

^a ST BARTHOLOMEW S HOSPITAL   (United Kingdom)

^b QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^c ROYAL LONDON HOSPITAL   (United Kingdom)

Author keywords

Breast carcinoma; Fine needle aspiration cytology; Immunohistochemistry; Integrins

Indexed keywords

INTEGRIN; PROTEIN SUBUNIT;

ADULT; AGED; ARTICLE; ASPIRATION BIOPSY; AXILLARY LYMPH NODE; BREAST CANCER; CANCER ADJUVANT THERAPY; CANCER CELL; CELL ADHESION; CLINICAL TRIAL; CYTOLOGY; DIAGNOSTIC VALUE; EXTRACELLULAR MATRIX; FEMALE; FROZEN SECTION; HISTOLOGY; HUMAN; IMMUNOCYTOCHEMISTRY; IMMUNOHISTOCHEMISTRY; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION;

EID: 0030011206     PISSN: 07487983     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0748-7983(96)80013-8     Document Type: Article

References (31)

1. Hynes RO. Integrins: a family of cell surface receptors. Cell 1987; 48: 549-54.
2. Albelda SM, Buck CA. Integrins and other cell adhesion molecules. FASEB J 1990; 4: 2868-80.
3. Koukoulis GK, Virtanen I, Korhonen M, Laitenen L, Quaranta V, Gould VE. Immunohistochemical localisation of integrins in the normal, hyperplastic, and neoplastic breast. Am J Pathol 1991; 139: 787-99.
4. Pignatelli M, Smith MEF, Bodmer WF. Low expression of collagen receptors in moderate and poorly differentiated colorectal adenocarcinomas. Br J Cancer 1990; 61: 636-8.
5. Hall PA, Coates P, Lemoine NR, Horton MA. Characterization of integrin chains in normal and neoplastic human pancreas. J Pathol 1991; 165: 33-41.
6. Albelda SM, Mette SA, Elder DE, et al. Integrin distribution in malignant melanoma: association of the β3 subunit with tumour progression. Cancer Res 1990; 50: 6757-64.
7. Peltonen J, Larjava H, Jaakkola S, et al. Localisation of integrin receptors for fibronectin, collagen, and laminin in human skin. Variable expression in basal and squamous cell carcinomas. J Clin Invest 1989; 84: 1916-23.
8. Gui GPH, Wells CA, Browne PD, et al. Integrin expression in primary breast cancer and its relation to axillary nodal status. Surgery 1995; 117: 102-8.
9. Kissin MW, Thompson EM, Price AB, Slavin G, Klark AE. The inadequacy of axillary sampling in breast cancer. Lancet 1982; 1: 1210-1.
10. Robinson IA, McKee G, Nicholson A, D'Arcy J, Jackson PA, Cook MG, Kissin MW. Prognostic value of cytological grading of fine-needle aspirates from breast carcinoma. Lancet 1994; 343: 947-9.
11. Hemler ME, Sanchez-Madrid F, Flotte TJ, et al. Glycoproteins of 210,000 and 130,000 M.W. on activated T cells: cell distribution and antigenic relation to components on resting cells and T cell lines. J Immunol 1984; 132: 3011-8.
12. Carter WG, Wayner EA, Bouchard TS, Kaur P. The role of integrins α2β1 and α3β1 in cell-cell and cell-substrate adhesion of human epidermal cells. J Cell Biol 1990; 110: 1387-404.
13. Sonnenberg A, Janssen H, Hogervorst F, Calafat J, Hilgers J. A complex of platelet glycoproteins Ic and IIa identified by a rat monoclonal antibody. J Biol Chem 1987; 262: 10376-83.
14. Cheresh DA. Human endothelial cells synthesize and express an Arg-Gly-Asp-directed receptor involved in attachment to fibrinogen and von Willebrand factor. Proc Natl Acad Sci USA 1987; 84: 6471-5.
15. r 140,000 fibronectin receptor complex in normal and virus-transformed human fibroblasts and in fibrosarcoma cells: identical localisation and Function. Int J Cancer 1989; 43: 1126-36.
16. Metzelaar MJ, Korteweg J, Sixma JJ, Nieuwenhaus HK. Biochemical characterization of PECAM-1 (CD31 antigen) on human platelets. Thromb Haem 1991; 66: 700-7.
17. Weinecker A, Chen A, Agrez M, et al. Role of the integrin αvβ6 in cell attachment to fibronectin. Heterologous expression of intact and secreted forms of the receptor. J Biol Chem 1994; 269: 6940-8.
18. Elston CW. Grading of invasive carcinoma of the breast. In: Page DL, Anderson TJ (eds) Diagnostic Histopathology of the Breast. Edinburgh: Churchill Livingstone, 1987: 300-11.
19. Dedhar S, Saulnier R. Alterations in integrin receptor expression on chemically transformed human cells: specific enhancement of laminin and collagen receptors. J Cell Biol 1990; 110: 481-9.
20. Zutter MM, Mazoujian G, Santoro SA. Decreased expression of integrin adhesive protein receptors in adenocarcinoma of the breast. Am J Pathol 1990; 137: 863-70.
21. Pignatelli M, Cardillo MR, Hanby A, Stamp GWH. Integrins and their accessory adhesion molecules in mammary carcinomas: loss of polarization in poorly differentiated tumours. Hum Pathol 1992; 23: 1159-66.
22. Steele RJC, Forrest APM, Gipson T, et al. The efficacy of lower axillary sampling in obtaining lymph node status in breast cancer: a controlled randomised trial. Br J Surg 1985; 72: 368-9.
23. Sacks NPM, Barr LC, Allan SM, Baum M. The role of axillary dissection in operable breast cancer. The Breast 1992; 1: 41-9.
24. Fentiman I, Mansel R. The axilla: not a no-go zone. Lancet 1991; 337: 221-3.
25. Kissin MW, Querco della Rovere G, Easton, Westbury G. Risk of lymphoedema following the treatment of breast cancer. Br J Surg 1986; 73: 580-4.
26. Nemato T, Vana J, Bedwani R, et al. Management and survival of female breast cancer: results of a national survey by American College of Surgeons. Cancer 1980; 45: 2917-24.
27. Recht A, Connally S, Schmitt J, et al. Conservative surgery and radiation therapy for early breast cancer: results, controversies and unsolved problems. Semin Oncol 1986; 13: 434-9.
28. Haybittle J, Blamey R, Elston C. A prognostic index in primary breast cancer. Br J Cancer 1982; 45: 361-6.
29. Todd J, Darle C, Williams M, et al. Confirmation of a prognostic index in primary breast cancer. Br J Cancer 1987; 56: 489-92.
30. Morgan D, Sibbering D, Galea M, Ellis, I, Elston C, Blamey R. Selection for adjuvant therapy using the Nottingham Prognostic index. Breast 1993; 2: 206.
31. Hart IR, Saini A. Biology of tumour metastasis. Lancet 1992; 339: 1453-7.