Rigidity sensing at the leading edge through αvβ3 integrins and RPTPα

Biophysical Journal

Volumn 90, Issue 5, 2006, Pages 1804-1809

  Jiang, Guoying ^a   Huang, Angela H ^a   Cai, Yunfei ^a   Tanase, Monica ^a   Sheetz, Michael P ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; BETA1 INTEGRIN; COLLAGEN TYPE 4; FIBRONECTIN; INTEGRIN; POLYACRYLAMIDE; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE PHOSPHATASE SHP 2; TALIN; CELL SURFACE RECEPTOR; LEUKOCYTE COMMON ANTIGEN RELATED PHOSPHATASE; LEUKOCYTE COMMON ANTIGEN-RELATED PHOSPHATASE; PROTEIN TYROSINE PHOSPHATASE; VITRONECTIN RECEPTOR;

ARTICLE; BINDING AFFINITY; CALCULATION; CELL LINE; CYTOSKELETON; ENZYME ACTIVATION; LASER; PROTEIN LOCALIZATION; RIGIDITY; ANIMAL; CELL ADHESION; CELL CULTURE; CELL MOTION; CYTOLOGY; ELASTICITY; EXTRACELLULAR MATRIX; FIBROBLAST; HARDNESS; MECHANICAL STRESS; MECHANOTRANSDUCTION; METABOLISM; MOUSE; PHYSIOLOGY;

ANIMALS; CELL ADHESION; CELL MOVEMENT; CELLS, CULTURED; ELASTICITY; EXTRACELLULAR MATRIX; FIBROBLASTS; HARDNESS; INTEGRIN ALPHAVBETA3; MECHANOTRANSDUCTION, CELLULAR; MICE; PROTEIN-TYROSINE-PHOSPHATASE; RECEPTORS, CELL SURFACE; STRESS, MECHANICAL;

EID: 33646155963     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1529/biophysj.105.072462     Document Type: Article

References (33)

1. Lo, C. M., H. B. Wang, M. Dembo, and Y. L. Wang. 2000. Cell movement is guided by the rigidity of the substrate. Biophys. J. 79:144-152.
2. Pelham, R. J. Jr., and Y. Wang. 1997. Cell locomotion and focal adhesions are regulated by substrate flexibility. Proc. Natl. Acad. Sci. USA. 94:13661-13665.
3. Beningo, K. A., C. M. Lo, and Y. L. Wang. 2002. Flexible polyacrylamide substrata for the analysis of mechanical interactions at cell-substratum adhesions. Methods Cell Biol. 69:325-339.
4. Cukierman, E., R. Pankov, D. R. Stevens, and K. M. Yamada. 2001. Taking cell-matrix adhesions to the third dimension. Science. 294:1708-1712.
5. Georges, P. C., and P. A. Janmey. 2005. Cell type-specific response to growth on soft materials. J. Appl. Physiol. 98:1547-1553.
6. Yeung, T., P. C. Georges, L. A. Flanagan, B. Marg, M. Ortiz, M. Funaki, N. Zahir, W. Ming, V. Weaver, and P. A. Janmey. 2005. Effects of substrate stiffness on cell morphology, cytoskeletal structure, and adhesion. Cell Motil. Cytoskeleton. 60:24-34.
7. Sieminski, A. L., R. P. Hebbel, and K. J. Gooch. 2004. The relative magnitudes of endothelial force generation and matrix stiffness modulate capillary morphogenesis in vitro. Exp. Cell Res. 297:574-584.
8. Engler, A. J., M. A. Griffin, S. Sen, C. G. Bonnemann, H. L. Sweeney, and D. E. Discher. 2004. Myotubes differentiate optimally on substrates with tissue-like stiffness: pathological implications for soft or stiff microenvironments. J. Cell Biol. 166:877-887.
9. Semler, E. J., C. S. Ranucci, and P. V. Moghe. 2000. Mechanochemical manipulation of hepatocyte aggregation can selectively induce or repress liver-specific function. Biotechnol. Bioeng. 69:359-369.
10. Wang, H. B., M. Dembo, and Y. L. Wang. 2000. Substrate flexibility regulates growth and apoptosis of normal but not transformed cells. Am. J. Physiol. Cell Physiol. 279:C1345-C1350.
11. Putman, D. L., D. K. Park, J. S. Rhim, A. F. Steuer, and R. C. Ting. 1977. Correlation of cellular aggregation of transformed cells with their growth in soft agar and tumorigenic potential. Proc. Soc. Exp. Biol. Med. 155:487-494.
12. Flanagan, L. A., Y. E. Ju, B. Marg, M. Osterfield, and P. A. Janmey. 2002. Neurite branching on deformable substrates. Neuroreport. 13:2411-2415.
13. Kusaka, K., Y. Harihara, G. Torzilli, K. Kubota, T. Takayama, M. Makuuchi, M. Mori, and S. Omata. 2000. Objective evaluation of liver consistency to estimate hepatic fibrosis and functional reserve for hepatectomy. J. Am. Coll. Surg. 191:47-53.
14. Wong, J. Y., A. Velasco, P. Rajagopala, and Q. Pham. 2003. Directed movement of vascular smooth muscle cells on gradient-compliant hydrogels. Langmuir. 19:1908-1913.
15. Felsenfeld, D. P., D. Choquet, and M. P. Sheetz. 1996. Ligand binding regulates the directed movement of beta1 integrins on fibroblasts. Nature. 383:438-440.
16. Schwarz, U. S., N. Q. Balaban, D. Riveline, A. Bershadsky, B. Geiger, and S. A. Safran. 2002. Calculation of forces at focal adhesions from elastic substrate data: the effect of localized force and the need for regularization. Biophys. J. 83:1380-1394.
17. Mandeville, J. T., and F. R. Maxfield. 1997. Effects of buffering intracellular free calcium on neutrophil migration through three-dimensional matrices. J. Cell. Physiol. 171:168-178.
18. Giannone, G., B. J. Dubin-Thaler, H. G. Dobereiner, N. Kieffer, A. R. Bresnick, and M. P. Sheetz. 2004. Periodic lamellipodial contractions correlate with rearward actin waves. Cell. 116:431-443.
19. Aznavoorian, S., M. L. Stracke, J. Parsons, J. McClanahan, and L. A. Liotta. 1996. Integrin alphavbeta3 mediates chemotactic and haptotactic motility in human melanoma cells through different signaling pathways. J. Biol. Chem. 271:3247-3254.
20. Li, X., B. Chen, S. D. Blystone, K. P. McHugh, F. P. Ross, and D. M. Ramos. 1998. Differential expression of alphav integrins in K1735 melanoma cells. Invasion Metastasis. 18:1-14.
21. Kiosses, W. B., S. J. Shattil, N. Pampori, and M. A. Schwartz. 2001. Rac recruits high-affinity integrin alphavbeta3 to lamellipodia in endothelial cell migration. Nat. Cell Biol. 3:316-320.
22. von Wichert, G., G. Jiang, A. Kostic, K. De Vos, J. Sap, and M. P. Sheetz. 2003. RPTP-alpha acts as a transducer of mechanical force on alphav/beta3-integrin-cytoskeleton linkages. J. Cell Biol. 161:143-153.
23. Ponniah, S., D. Z. Wang, K. L. Lim, and C. J. Pallen. 1999. Targeted disruption of the tyrosine phosphatase PTPalpha leads to constitutive downregulation of the kinases Src and Fyn. Curr. Biol. 9:535-538.
24. Su, J., M. Muranjan, and J. Sap. 1999. Receptor protein tyrosine phosphatase alpha activates Src-family kinases and controls integrin-mediated responses in fibroblasts. Curr. Biol. 9:505-511.
25. Petrone, A., F. Battaglia, C. Wang, A. Dusa, J. Su, D. Zagzag, R. Bianchi, P. Casaccia-Bonnefil, O. Arancio, and J. Sap. 2003. Receptor protein tyrosine phosphatase alpha is essential for hippocampal neuronal migration and long-term potentiation. EMBO J. 22:4121-4131.
26. Jiang, G., G. Giannone, D. R. Critchley, E. Fukumoto, and M. P. Sheetz. 2003. Two-piconewton slip bond between fibronectin and the cytoskeleton depends on talin. Nature. 424:334-337.
27. Chen, B. H., J. T. Tzen, A. R. Bresnick, and H. C. Chen. 2002. Roles of Rho-associated kinase and myosin light chain kinase in morphological and migratory defects of focal adhesion kinase-null cells. J. Biol. Chem. 277:33857-33863.
28. Avizienyte, E., A. W. Wyke, R. J. Jones, G. W. McLean, M. A. Westhoff, V. G. Brunton, and M. C. Frame. 2002. Src-induced deregulation of E-cadherin in colon cancer cells requires integrin signalling. Nat. Cell Biol. 4:632-638.
29. Levinson, H., J. E. Hopper, and H. P. Ehrlich. 2002. Overexpression of integrin alphav promotes human osteosarcoma cell populated collagen lattice contraction and cell migration. J. Cell. Physiol. 193:219-224.
30. Kaido, T., M. Yebra, V. Cirulli, and A. M. Montgomery. 2004. Regulation of human beta-cell adhesion, motility, and insulin secretion by collagen IV and its receptor alpha1beta1. J. Biol. Chem. 279:53762-53769.
31. Giannone, G., G. Jiang, D. H. Sutton, D. R. Critchley, and M. P. Sheetz. 2003. Talin1 is critical for force-dependent reinforcement of initial integrin-cytoskeleton bonds but not tyrosine kinase activation. J. Cell Biol. 163:409-419.
32. Tamada, M., M. P. Sheetz, and Y. Sawada. 2004. Activation of a signaling cascade by cytoskeleton stretch. Dev. Cell. 7:709-718.
33. Abassi, Y. A., M. Rehn, N. Ekman, K. Alitalo, and K. Vuori. 2003. p130Cas couples the tyrosine kinase Bmx/Etk with regulation of the actin cytoskeleton and cell migration. J. Biol. Chem. 278:35636-35643.