Spinal anandamide produces analgesia in neuropathic rats: Possible CB 1- and TRPV1-mediated mechanisms

Neuropharmacology

Volumn 62, Issue 4, 2012, Pages 1746-1755

  Starowicz, K ^a   Makuch, W ^a   Osikowicz, M ^a   Piscitelli, F ^b   Petrosino, S ^b   Di Marzo, V ^b   Przewlocka, B ^a  

^a INSTITUTE OF PHARMACOLOGY   (Poland)

^b CNR Consiglio Nazionale delle Ricerche   (Italy)

Author keywords

Anandamide (AEA); Cannabinoid type 1 receptor (CB 1); Fatty acid amide hydrolase (FAAH); Neuropathic pain; Spinal cord; Transient receptor potential vanilloid type 1 (TRPV1)

Indexed keywords

ANANDAMIDE; CANNABINOID 1 RECEPTOR; CYCLOHEXYLCARBAMIC ACID 3' CARBAMOYLBIPHENYL 3 YL ESTER; VANILLOID RECEPTOR 1;

ALLODYNIA; ANALGESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG MECHANISM; DRUG POTENTIATION; DRUG RECEPTOR BINDING; DRUG TARGETING; HYPERALGESIA; LOW DRUG DOSE; MALE; NEUROPATHIC PAIN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; RECEPTOR BLOCKING;

ANALGESIA; ANIMALS; ARACHIDONIC ACIDS; ENDOCANNABINOIDS; HYPERALGESIA; MALE; NEURALGIA; PAIN MEASUREMENT; POLYUNSATURATED ALKAMIDES; RATS; RATS, WISTAR; RECEPTOR, CANNABINOID, CB1; SCIATIC NERVE; TRPV CATION CHANNELS;

EID: 84856442156     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2011.11.021     Document Type: Article

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