-
1
-
-
0036445885
-
Vascular patterning by Eph receptor tyrosine kinases and ephrins
-
10.1006/scdb.2001.0289, 11969371
-
Adams RH. Vascular patterning by Eph receptor tyrosine kinases and ephrins. Semin Cell Dev Biol 2002, 13(1):55-60. 10.1006/scdb.2001.0289, 11969371.
-
(2002)
Semin Cell Dev Biol
, vol.13
, Issue.1
, pp. 55-60
-
-
Adams, R.H.1
-
2
-
-
20344396123
-
Eph receptor signalling casts a wide net on cell behaviour
-
10.1038/nrm1662, 15928710
-
Pasquale EB. Eph receptor signalling casts a wide net on cell behaviour. Nat Rev Mol Cell Biol 2005, 6(6):462-475. 10.1038/nrm1662, 15928710.
-
(2005)
Nat Rev Mol Cell Biol
, vol.6
, Issue.6
, pp. 462-475
-
-
Pasquale, E.B.1
-
3
-
-
34247615569
-
Bidirectional Eph-ephrin signaling during axon guidance
-
10.1016/j.tcb.2007.03.004, 17420126
-
Egea J, Klein R. Bidirectional Eph-ephrin signaling during axon guidance. Trends Cell Biol 2007, 17(5):230-238. 10.1016/j.tcb.2007.03.004, 17420126.
-
(2007)
Trends Cell Biol
, vol.17
, Issue.5
, pp. 230-238
-
-
Egea, J.1
Klein, R.2
-
4
-
-
41149102101
-
Development of Continuous and Discrete Neural Maps
-
10.1016/j.neuron.2007.10.014, 17964246
-
Luo L, Flanagan JG. Development of Continuous and Discrete Neural Maps. Neuron 2007, 56(2):284-300. 10.1016/j.neuron.2007.10.014, 17964246.
-
(2007)
Neuron
, vol.56
, Issue.2
, pp. 284-300
-
-
Luo, L.1
Flanagan, J.G.2
-
5
-
-
33344471782
-
Eph receptor and ephrin ligand-mediated interactions during angiogenesis and tumor progression
-
10.1016/j.yexcr.2005.10.028, 16330025
-
Heroult M, Schaffner F, Augustin HG. Eph receptor and ephrin ligand-mediated interactions during angiogenesis and tumor progression. Exp Cell Res 2006, 312(5):642-650. 10.1016/j.yexcr.2005.10.028, 16330025.
-
(2006)
Exp Cell Res
, vol.312
, Issue.5
, pp. 642-650
-
-
Heroult, M.1
Schaffner, F.2
Augustin, H.G.3
-
6
-
-
41149084179
-
Eph-ephrin bidirectional signaling in physiology and disease
-
10.1016/j.cell.2008.03.011, 18394988
-
Pasquale EB. Eph-ephrin bidirectional signaling in physiology and disease. Cell 2008, 133(1):38-52. 10.1016/j.cell.2008.03.011, 18394988.
-
(2008)
Cell
, vol.133
, Issue.1
, pp. 38-52
-
-
Pasquale, E.B.1
-
7
-
-
0035855819
-
The SH2/SH3 adaptor Grb4 transduces B-ephrin reverse signals
-
10.1038/35093123, 11557983
-
Cowan CA, Henkemeyer M. The SH2/SH3 adaptor Grb4 transduces B-ephrin reverse signals. Nature 2001, 413:174-179. 10.1038/35093123, 11557983.
-
(2001)
Nature
, vol.413
, pp. 174-179
-
-
Cowan, C.A.1
Henkemeyer, M.2
-
8
-
-
0042591409
-
Tyrosine phosphorylation of the well packed ephrinB cytoplasmic beta-hairpin for reverse signaling. Structural consequences and binding properties
-
10.1074/jbc.M210625200, 12606549
-
Song J. Tyrosine phosphorylation of the well packed ephrinB cytoplasmic beta-hairpin for reverse signaling. Structural consequences and binding properties. J Biol Chem 2003, 278:24714-24720. 10.1074/jbc.M210625200, 12606549.
-
(2003)
J Biol Chem
, vol.278
, pp. 24714-24720
-
-
Song, J.1
-
9
-
-
0032480889
-
Crystal structure of the ligand-binding domain of the receptor tyrosine kinase EphB2
-
10.1038/24904, 9853759
-
Himanen JP, Henkemeyer M, Nikolov DB. Crystal structure of the ligand-binding domain of the receptor tyrosine kinase EphB2. Nature 1998, 396:486-491. 10.1038/24904, 9853759.
-
(1998)
Nature
, vol.396
, pp. 486-491
-
-
Himanen, J.P.1
Henkemeyer, M.2
Nikolov, D.B.3
-
10
-
-
35548948069
-
Cell-cell signalling via Eph receptors and ephrins
-
10.1016/j.ceb.2007.08.004, 17928214
-
Himanen JP, Saha N, Nikolov DB. Cell-cell signalling via Eph receptors and ephrins. Curr Opin Cell Biol 2007, 19(5):534-542. 10.1016/j.ceb.2007.08.004, 17928214.
-
(2007)
Curr Opin Cell Biol
, vol.19
, Issue.5
, pp. 534-542
-
-
Himanen, J.P.1
Saha, N.2
Nikolov, D.B.3
-
11
-
-
0035924322
-
Crystal structure of an Eph receptor-ephrin complex
-
10.1038/414933a, 11780069
-
Himanen JP, Rajashankar KR, Lackmann M, Cowan CA, Henkemeyer M, Nikolov DB. Crystal structure of an Eph receptor-ephrin complex. Nature 2001, 414:933-938. 10.1038/414933a, 11780069.
-
(2001)
Nature
, vol.414
, pp. 933-938
-
-
Himanen, J.P.1
Rajashankar, K.R.2
Lackmann, M.3
Cowan, C.A.4
Henkemeyer, M.5
Nikolov, D.B.6
-
12
-
-
67650079305
-
Ligand recognition by A-class Eph receptors: crystal structures of the EphA2 ligand-binding domain and the EphA2/ephrin-A1 complex
-
10.1038/embor.2009.91, 2727437, 19525919
-
Himanen JP, Goldgur Y, Miao H, Myshkin E, Guo H, Buck M, Nguyen M, Rajashankar KR, Wang B, Nikolov DB. Ligand recognition by A-class Eph receptors: crystal structures of the EphA2 ligand-binding domain and the EphA2/ephrin-A1 complex. EMBO Rep 2009, 10:722-8. 10.1038/embor.2009.91, 2727437, 19525919.
-
(2009)
EMBO Rep
, vol.10
, pp. 722-728
-
-
Himanen, J.P.1
Goldgur, Y.2
Miao, H.3
Myshkin, E.4
Guo, H.5
Buck, M.6
Nguyen, M.7
Rajashankar, K.R.8
Wang, B.9
Nikolov, D.B.10
-
13
-
-
70349774556
-
Structural plasticity of eph receptor A4 facilitates cross-class ephrin signaling
-
10.1016/j.str.2009.07.018, 2832735, 19836338
-
Bowden TA, Aricescu AR, Nettleship JE, Siebold C, Rahman-Huq N, Owens RJ, Stuart DI, Jones EY. Structural plasticity of eph receptor A4 facilitates cross-class ephrin signaling. Structure 2009, 17:1386-97. 10.1016/j.str.2009.07.018, 2832735, 19836338.
-
(2009)
Structure
, vol.17
, pp. 1386-1397
-
-
Bowden, T.A.1
Aricescu, A.R.2
Nettleship, J.E.3
Siebold, C.4
Rahman-Huq, N.5
Owens, R.J.6
Stuart, D.I.7
Jones, E.Y.8
-
14
-
-
57649186979
-
Crystal structure and NMR binding reveal that two small molecule antagonists target the high affinity ephrin-binding channel of the EphA4 receptor
-
10.1074/jbc.M804114200, 2662028, 18708347
-
Qin H, Shi J, Noberini R, Pasquale EB, Song J. Crystal structure and NMR binding reveal that two small molecule antagonists target the high affinity ephrin-binding channel of the EphA4 receptor. J Biol Chem 2008, 283:29473-29484. 10.1074/jbc.M804114200, 2662028, 18708347.
-
(2008)
J Biol Chem
, vol.283
, pp. 29473-29484
-
-
Qin, H.1
Shi, J.2
Noberini, R.3
Pasquale, E.B.4
Song, J.5
-
15
-
-
77956262547
-
Crystal structure of the ligand-binding domain of the promiscuous EphA4 receptor reveals two distinct conformations
-
10.1016/j.bbrc.2010.07.109, 2949057, 20678482
-
Singla N, Goldgur Y, Xu K, Paavilainen S, Nikolov DB, Himanen JP. Crystal structure of the ligand-binding domain of the promiscuous EphA4 receptor reveals two distinct conformations. Biochem Biophys Res Commun 2010, 399:555-559. 10.1016/j.bbrc.2010.07.109, 2949057, 20678482.
-
(2010)
Biochem Biophys Res Commun
, vol.399
, pp. 555-559
-
-
Singla, N.1
Goldgur, Y.2
Xu, K.3
Paavilainen, S.4
Nikolov, D.B.5
Himanen, J.P.6
-
16
-
-
77950516909
-
An extracellular steric seeding mechanism for Eph-ephrin signaling platform assembly
-
10.1038/nsmb.1782, 20228801
-
Seiradake E, Harlos K, Sutton G, Aricescu AR, Jones EY. An extracellular steric seeding mechanism for Eph-ephrin signaling platform assembly. Nat Struct Mol Biol 2010, 17(4):398-402. 10.1038/nsmb.1782, 20228801.
-
(2010)
Nat Struct Mol Biol
, vol.17
, Issue.4
, pp. 398-402
-
-
Seiradake, E.1
Harlos, K.2
Sutton, G.3
Aricescu, A.R.4
Jones, E.Y.5
-
17
-
-
77954627688
-
Architecture of Eph receptor clusters
-
Himanen JP, Yermekbayeva L, Janes PW, Walker JR, Xu K, Atapattu L, Rajashankar KR, Mensinga A, Lackmann M, Nikolov DB, Dhe-Paganon S. Architecture of Eph receptor clusters. Proc Natl Acad Sci USA 2010, 24:10860-5.
-
(2010)
Proc Natl Acad Sci USA
, vol.24
, pp. 10860-10865
-
-
Himanen, J.P.1
Yermekbayeva, L.2
Janes, P.W.3
Walker, J.R.4
Xu, K.5
Atapattu, L.6
Rajashankar, K.R.7
Mensinga, A.8
Lackmann, M.9
Nikolov, D.B.10
Dhe-Paganon, S.11
-
18
-
-
73649128536
-
Structural characterization of the EphA4-Ephrin-B2 complex reveals new features enabling Eph-ephrin binding promiscuity
-
10.1074/jbc.M109.064824, 2804212, 19875447
-
Qin H, Noberini R, Huan X, Shi J, Pasquale EB, Song J. Structural characterization of the EphA4-Ephrin-B2 complex reveals new features enabling Eph-ephrin binding promiscuity. J Biol Chem 2010, 285:644-654. 10.1074/jbc.M109.064824, 2804212, 19875447.
-
(2010)
J Biol Chem
, vol.285
, pp. 644-654
-
-
Qin, H.1
Noberini, R.2
Huan, X.3
Shi, J.4
Pasquale, E.B.5
Song, J.6
-
19
-
-
33748781688
-
Structural and biophysical characterization of the EphB4*ephrinB2 protein-protein interaction and receptor specificity
-
10.1074/jbc.M605766200, 16867992
-
Chrencik JE, Brooun A, Kraus ML, Recht MI, Kolatkar AR, Han GW, Seifert JM, Widmer H, Auer M, Kuhn P. Structural and biophysical characterization of the EphB4*ephrinB2 protein-protein interaction and receptor specificity. J Biol Chem 2006, 281:28185-92. 10.1074/jbc.M605766200, 16867992.
-
(2006)
J Biol Chem
, vol.281
, pp. 28185-28192
-
-
Chrencik, J.E.1
Brooun, A.2
Kraus, M.L.3
Recht, M.I.4
Kolatkar, A.R.5
Han, G.W.6
Seifert, J.M.7
Widmer, H.8
Auer, M.9
Kuhn, P.10
-
20
-
-
11144354644
-
Repelling class discrimination: ephrin-A5 binds to and activates EphB2 receptor signaling
-
10.1038/nn1237, 15107857
-
Himanen JP, Chumley MJ, Lackmann M, Li C, Barton WA, Jeffrey PD, Vearing C, Geleick D, Feldheim DA, Boyd AW, Henkemeyer M, Nikolov DB. Repelling class discrimination: ephrin-A5 binds to and activates EphB2 receptor signaling. Nat Neurosci 2004, 7:501-509. 10.1038/nn1237, 15107857.
-
(2004)
Nat Neurosci
, vol.7
, pp. 501-509
-
-
Himanen, J.P.1
Chumley, M.J.2
Lackmann, M.3
Li, C.4
Barton, W.A.5
Jeffrey, P.D.6
Vearing, C.7
Geleick, D.8
Feldheim, D.A.9
Boyd, A.W.10
Henkemeyer, M.11
Nikolov, D.B.12
-
21
-
-
37549017344
-
Three-dimensional structure of the EphB2 receptor in complex with an antagonistic peptide reveals a novel mode of inhibition
-
10.1074/jbc.M706340200, 17897949
-
Chrencik JE, Brooun A, Recht MI, Nicola G, Davis LK, Abagyan R, Widmer H, Pasquale EB, Kuhn P. Three-dimensional structure of the EphB2 receptor in complex with an antagonistic peptide reveals a novel mode of inhibition. J Biol Chem 2007, 282:36505-13. 10.1074/jbc.M706340200, 17897949.
-
(2007)
J Biol Chem
, vol.282
, pp. 36505-36513
-
-
Chrencik, J.E.1
Brooun, A.2
Recht, M.I.3
Nicola, G.4
Davis, L.K.5
Abagyan, R.6
Widmer, H.7
Pasquale, E.B.8
Kuhn, P.9
-
22
-
-
32044470909
-
Structure and thermodynamic characterization of the EphB4/Ephrin-B2 antagonist peptide complex reveals the determinants for receptor specificity
-
10.1016/j.str.2005.11.011, 16472751
-
Chrencik JE, Brooun A, Recht MI, Kraus ML, Koolpe M, Kolatkar AR, Bruce RH, Martiny-Baron G, Widmer H, Pasquale EB, Kuhn P. Structure and thermodynamic characterization of the EphB4/Ephrin-B2 antagonist peptide complex reveals the determinants for receptor specificity. Structure 2006, 14:321-30. 10.1016/j.str.2005.11.011, 16472751.
-
(2006)
Structure
, vol.14
, pp. 321-330
-
-
Chrencik, J.E.1
Brooun, A.2
Recht, M.I.3
Kraus, M.L.4
Koolpe, M.5
Kolatkar, A.R.6
Bruce, R.H.7
Martiny-Baron, G.8
Widmer, H.9
Pasquale, E.B.10
Kuhn, P.11
-
23
-
-
47349103543
-
NMR structure and dynamics of human ephrin-B2 ectodomain: the functionally critical C-D and G-H loops are highly dynamic in solution
-
10.1002/prot.21999, 18300229
-
Ran X, Qin H, Liu J, Fan JS, Shi J, Song J. NMR structure and dynamics of human ephrin-B2 ectodomain: the functionally critical C-D and G-H loops are highly dynamic in solution. Proteins 2008, 72:1019-1029. 10.1002/prot.21999, 18300229.
-
(2008)
Proteins
, vol.72
, pp. 1019-1029
-
-
Ran, X.1
Qin, H.2
Liu, J.3
Fan, J.S.4
Shi, J.5
Song, J.6
-
24
-
-
2142764419
-
Eph-ephrin promiscuity is now crystal clear
-
10.1038/nn0504-417, 15114347
-
Pasquale EB. Eph-ephrin promiscuity is now crystal clear. Nat Neurosci 2004, 7(5):417-418. 10.1038/nn0504-417, 15114347.
-
(2004)
Nat Neurosci
, vol.7
, Issue.5
, pp. 417-418
-
-
Pasquale, E.B.1
-
25
-
-
34748829242
-
The EphA4 receptor regulates dendritic spine remodeling by affecting beta1-integrin signaling pathways
-
10.1083/jcb.200610139, 2064660, 17875741
-
Bourgin C, Murai KK, Richter M, Pasquale EB. The EphA4 receptor regulates dendritic spine remodeling by affecting beta1-integrin signaling pathways. J Cell Biol 2007, 178:1295-307. 10.1083/jcb.200610139, 2064660, 17875741.
-
(2007)
J Cell Biol
, vol.178
, pp. 1295-1307
-
-
Bourgin, C.1
Murai, K.K.2
Richter, M.3
Pasquale, E.B.4
-
26
-
-
38449105906
-
The EphA4 receptor regulates neuronal morphology through SPAR-mediated inactivation of Rap GTPases
-
10.1523/JNEUROSCI.2746-07.2007, 18094260
-
Richter M, Murai KK, Bourgin C, Pak DT, Pasquale EB. The EphA4 receptor regulates neuronal morphology through SPAR-mediated inactivation of Rap GTPases. J Neurosci 2007, 27:14205-15. 10.1523/JNEUROSCI.2746-07.2007, 18094260.
-
(2007)
J Neurosci
, vol.27
, pp. 14205-14215
-
-
Richter, M.1
Murai, K.K.2
Bourgin, C.3
Pak, D.T.4
Pasquale, E.B.5
-
27
-
-
42049101832
-
Segregation of axial motor and sensory pathways via heterotypic trans-axonal signaling
-
10.1126/science.1153758, 3158657, 18403711
-
Gallarda BW, Bonanomi D, Müller D, Brown A, Alaynick WA, Andrews SE, Lemke G, Pfaff SL, Marquardt T. Segregation of axial motor and sensory pathways via heterotypic trans-axonal signaling. Science 2008, 320:233-6. 10.1126/science.1153758, 3158657, 18403711.
-
(2008)
Science
, vol.320
, pp. 233-236
-
-
Gallarda, B.W.1
Bonanomi, D.2
Müller, D.3
Brown, A.4
Alaynick, W.A.5
Andrews, S.E.6
Lemke, G.7
Pfaff, S.L.8
Marquardt, T.9
-
28
-
-
22244469478
-
Eph kinases and ephrins support thrombus growth and stability by regulating integrin outside-in signaling in platelets
-
10.1073/pnas.0404065102, 1174973, 15994237
-
Prevost N, Woulfe DS, Jiang H, Stalker TJ, Marchese P, Ruggeri ZM, Brass LF. Eph kinases and ephrins support thrombus growth and stability by regulating integrin outside-in signaling in platelets. Proc Natl Acad Sci USA 2005, 102:9820-9825. 10.1073/pnas.0404065102, 1174973, 15994237.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 9820-9825
-
-
Prevost, N.1
Woulfe, D.S.2
Jiang, H.3
Stalker, T.J.4
Marchese, P.5
Ruggeri, Z.M.6
Brass, L.F.7
-
29
-
-
8544237780
-
Axonal regeneration and lack of astrocytic gliosis in EphA4-deficient mice
-
10.1523/JNEUROSCI.2981-04.2004, 15537875
-
Goldshmit Y, Galea MP, Wise G, Bartlett PF, Turnley AM. Axonal regeneration and lack of astrocytic gliosis in EphA4-deficient mice. J Neurosci 2004, 24:10064-10073. 10.1523/JNEUROSCI.2981-04.2004, 15537875.
-
(2004)
J Neurosci
, vol.24
, pp. 10064-10073
-
-
Goldshmit, Y.1
Galea, M.P.2
Wise, G.3
Bartlett, P.F.4
Turnley, A.M.5
-
30
-
-
23044477800
-
Ephrin-B3 is a myelin-based inhibitor of neurite outgrowth
-
10.1073/pnas.0504021102, 1175581, 16020529
-
Benson MD, Romero MI, Lush ME, Lu QR, Henkemeyer M, Parada LF. Ephrin-B3 is a myelin-based inhibitor of neurite outgrowth. Proc Natl Acad Sci USA 2005, 102:10694-9. 10.1073/pnas.0504021102, 1175581, 16020529.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 10694-10699
-
-
Benson, M.D.1
Romero, M.I.2
Lush, M.E.3
Lu, Q.R.4
Henkemeyer, M.5
Parada, L.F.6
-
31
-
-
34548405632
-
Eph/ephrin signaling as a potential therapeutic target after central nervous system injury
-
Du J, Fu C, Sretavan DW. Eph/ephrin signaling as a potential therapeutic target after central nervous system injury. Current pharmaceutical design 2007, 13:2507-2518.
-
(2007)
Current pharmaceutical design
, vol.13
, pp. 2507-2518
-
-
Du, J.1
Fu, C.2
Sretavan, D.W.3
-
32
-
-
57649178194
-
Small molecules can selectively inhibit ephrin binding to the EphA4 and EphA2 receptors
-
10.1074/jbc.M804103200, 2570887, 18728010
-
Noberini R, Koolpe M, Peddibhotla S, Dahl R, Su Y, Cosford ND, Roth GP, Pasquale EB. Small molecules can selectively inhibit ephrin binding to the EphA4 and EphA2 receptors. J Biol Chem 2008, 283(43):29461-72. 10.1074/jbc.M804103200, 2570887, 18728010.
-
(2008)
J Biol Chem
, vol.283
, Issue.43
, pp. 29461-29472
-
-
Noberini, R.1
Koolpe, M.2
Peddibhotla, S.3
Dahl, R.4
Su, Y.5
Cosford, N.D.6
Roth, G.P.7
Pasquale, E.B.8
-
33
-
-
3342993181
-
Hydrogen exchange methods to study protein folding
-
10.1016/j.ymeth.2004.03.005, 15283915
-
Krishna MM, Hoang L, Lin Y, Englander SW. Hydrogen exchange methods to study protein folding. Methods 2004, 34:51-64. 10.1016/j.ymeth.2004.03.005, 15283915.
-
(2004)
Methods
, vol.34
, pp. 51-64
-
-
Krishna, M.M.1
Hoang, L.2
Lin, Y.3
Englander, S.W.4
-
34
-
-
0033970020
-
Folding and binding cascades: dynamic landscapes and population shifts
-
2144430, 10739242
-
Kumar S, Ma B, Tsai CJ, Sinha N, Nussinov R. Folding and binding cascades: dynamic landscapes and population shifts. Protein Sci 2000, 9:10-19. 2144430, 10739242.
-
(2000)
Protein Sci
, vol.9
, pp. 10-19
-
-
Kumar, S.1
Ma, B.2
Tsai, C.J.3
Sinha, N.4
Nussinov, R.5
-
35
-
-
18744371588
-
Molecular dynamics and protein function
-
10.1073/pnas.0408930102, 1100762, 15870208
-
Karplus M, Kuriyan J. Molecular dynamics and protein function. Proc Natl Acad Sci USA 2005, 102:6679-6685. 10.1073/pnas.0408930102, 1100762, 15870208.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 6679-6685
-
-
Karplus, M.1
Kuriyan, J.2
-
36
-
-
64849111005
-
Sending Signals Dynamically
-
10.1126/science.1169377, 2921701, 19359576
-
Smock RG, Gierasch LM. Sending Signals Dynamically. Science 2009, 324:198-203. 10.1126/science.1169377, 2921701, 19359576.
-
(2009)
Science
, vol.324
, pp. 198-203
-
-
Smock, R.G.1
Gierasch, L.M.2
-
37
-
-
77957231785
-
Induced fit, conformational selection and independent dynamic segments: an extended view of binding events
-
10.1016/j.tibs.2010.04.009, 3018770, 20541943
-
Csermely P, Palotai R, Nussinov R. Induced fit, conformational selection and independent dynamic segments: an extended view of binding events. Trends Biochem Sci 2010, 35:539-546. 10.1016/j.tibs.2010.04.009, 3018770, 20541943.
-
(2010)
Trends Biochem Sci
, vol.35
, pp. 539-546
-
-
Csermely, P.1
Palotai, R.2
Nussinov, R.3
-
38
-
-
79958136745
-
A Role for Both Conformational Selection and Induced Fit in Ligand Binding by the LAO Protein
-
10.1371/journal.pcbi.1002054, 3102756, 21637799
-
Silva DA, Bowman GR, Sosa-Peinado A, Huang X. A Role for Both Conformational Selection and Induced Fit in Ligand Binding by the LAO Protein. PLoS Comput Biol 2011, 7:e1002054. 10.1371/journal.pcbi.1002054, 3102756, 21637799.
-
(2011)
PLoS Comput Biol
, vol.7
-
-
Silva, D.A.1
Bowman, G.R.2
Sosa-Peinado, A.3
Huang, X.4
-
39
-
-
79952463416
-
Dynamically-driven inactivation of the catalytic machinery of the SARS 3C-like protease by the N214A mutation on the extra domain
-
10.1371/journal.pcbi.1001084, 3044768, 21390281
-
Shi J, Han N, Lim L, Lua S, Sivaraman J, Wang L, Mu Y, Song J. Dynamically-driven inactivation of the catalytic machinery of the SARS 3C-like protease by the N214A mutation on the extra domain. PLoS Comput Biol 2011, 7:e1001084. 10.1371/journal.pcbi.1001084, 3044768, 21390281.
-
(2011)
PLoS Comput Biol
, vol.7
-
-
Shi, J.1
Han, N.2
Lim, L.3
Lua, S.4
Sivaraman, J.5
Wang, L.6
Mu, Y.7
Song, J.8
-
40
-
-
80055113691
-
Structural, Stability, Dynamic and Binding Properties of the ALS-Causing T46I Mutant of the hVAPB MSP Domain as Revealed by NMR and MD Simulations
-
10.1371/journal.pone.0027072, 3206076, 22069488
-
Lua S, et al. Structural, Stability, Dynamic and Binding Properties of the ALS-Causing T46I Mutant of the hVAPB MSP Domain as Revealed by NMR and MD Simulations. PLoS ONE 2011, 6:e27072. 10.1371/journal.pone.0027072, 3206076, 22069488.
-
(2011)
PLoS ONE
, vol.6
-
-
Lua, S.1
-
41
-
-
0001289724
-
Einfluss der Configuration auf die Wirkung der Enzyme
-
Fischer E. Einfluss der Configuration auf die Wirkung der Enzyme. Ber Dtsch Chem Ges 1894, 27:2984-2993.
-
(1894)
Ber Dtsch Chem Ges
, vol.27
, pp. 2984-2993
-
-
Fischer, E.1
-
42
-
-
0001858251
-
Application of a Theory of Enzyme Specificity to Protein Synthesis
-
10.1073/pnas.44.2.98, 335371, 16590179
-
Koshland DE. Application of a Theory of Enzyme Specificity to Protein Synthesis. Proc Natl Acad Sci USA 1958, 44:98-104. 10.1073/pnas.44.2.98, 335371, 16590179.
-
(1958)
Proc Natl Acad Sci USA
, vol.44
, pp. 98-104
-
-
Koshland, D.E.1
-
43
-
-
33750337737
-
Protein complex formation by acetylcholinesterase and the neurotoxin fasciculin-2 appears to involve an induced-fit mechanism
-
10.1073/pnas.0605355103, 1591298, 17021015
-
Bui JM, McCammon JA. Protein complex formation by acetylcholinesterase and the neurotoxin fasciculin-2 appears to involve an induced-fit mechanism. Proc Natl Acad Sci USA 2006, 103:15451-15456. 10.1073/pnas.0605355103, 1591298, 17021015.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 15451-15456
-
-
Bui, J.M.1
McCammon, J.A.2
-
44
-
-
33846625611
-
Fly-casting in protein-DNA binding: frustration between protein folding and electrostatics facilitates target recognition
-
10.1021/ja065531n, 17243791
-
Levy Y, Onuchic JN, Wolynes PG. Fly-casting in protein-DNA binding: frustration between protein folding and electrostatics facilitates target recognition. J Am Chem Soc 2007, 129:738-739. 10.1021/ja065531n, 17243791.
-
(2007)
J Am Chem Soc
, vol.129
, pp. 738-739
-
-
Levy, Y.1
Onuchic, J.N.2
Wolynes, P.G.3
-
45
-
-
0033784534
-
Induced fit in RNA-protein recognition
-
10.1038/79575, 11017187
-
Williamson JR. Induced fit in RNA-protein recognition. Nat Struct Biol 2000, 7:834-837. 10.1038/79575, 11017187.
-
(2000)
Nat Struct Biol
, vol.7
, pp. 834-837
-
-
Williamson, J.R.1
-
46
-
-
0036147568
-
Multiple diverse ligands binding at a single protein site: a matter of pre-existing populations
-
2373439, 11790828
-
Ma B, Shatsky M, Wolfson HJ, Nussinov R. Multiple diverse ligands binding at a single protein site: a matter of pre-existing populations. Protein Sci 2002, 11:184-197. 2373439, 11790828.
-
(2002)
Protein Sci
, vol.11
, pp. 184-197
-
-
Ma, B.1
Shatsky, M.2
Wolfson, H.J.3
Nussinov, R.4
-
47
-
-
0037470496
-
Antibody multispecificity mediated by conformational diversity
-
10.1126/science.1079731, 12610298
-
James LC, Roversi P, Tawfik DS. Antibody multispecificity mediated by conformational diversity. Science 2003, 299:1362-1367. 10.1126/science.1079731, 12610298.
-
(2003)
Science
, vol.299
, pp. 1362-1367
-
-
James, L.C.1
Roversi, P.2
Tawfik, D.S.3
-
48
-
-
79960189344
-
Dynamic allostery: linkers are not merely flexible
-
10.1016/j.str.2011.06.002, 21742258
-
Ma B, Tsai CJ, Haliloǧlu T, Nussinov R. Dynamic allostery: linkers are not merely flexible. Structure 2011, 19:907-17. 10.1016/j.str.2011.06.002, 21742258.
-
(2011)
Structure
, vol.19
, pp. 907-917
-
-
Ma, B.1
Tsai, C.J.2
Haliloǧlu, T.3
Nussinov, R.4
-
49
-
-
70350340728
-
The role of dynamic conformational ensembles in biomolecular recognition
-
10.1038/nchembio.232, 2916928, 19841628
-
Boehr DD, Nussinov R, Wright PE. The role of dynamic conformational ensembles in biomolecular recognition. Nat Chem Biol 2009, 5:789-96. 10.1038/nchembio.232, 2916928, 19841628.
-
(2009)
Nat Chem Biol
, vol.5
, pp. 789-796
-
-
Boehr, D.D.1
Nussinov, R.2
Wright, P.E.3
-
50
-
-
0347124700
-
Targeting the EphA4 receptor in the nervous system with biologically active peptides
-
Murai KK, Nguyen LN, Koolpe M, McLennan R, Krull CE, Pasquale EB. Targeting the EphA4 receptor in the nervous system with biologically active peptides. Mol Cell Neurosci 2003, 4:1000-11.
-
(2003)
Mol Cell Neurosci
, vol.4
, pp. 1000-1011
-
-
Murai, K.K.1
Nguyen, L.N.2
Koolpe, M.3
McLennan, R.4
Krull, C.E.5
Pasquale, E.B.6
-
51
-
-
79953306876
-
Lithocholic acid is an Eph-ephrin ligand interfering with Eph-kinase activation
-
10.1371/journal.pone.0018128, 3068151, 21479221
-
Giorgio C, Hassan Mohamed I, Flammini L, Barocelli E, Incerti M, Lodola A, Tognolini M. Lithocholic acid is an Eph-ephrin ligand interfering with Eph-kinase activation. PLoS One 2011, 6(3):e18128. 10.1371/journal.pone.0018128, 3068151, 21479221.
-
(2011)
PLoS One
, vol.6
, Issue.3
-
-
Giorgio, C.1
Hassan Mohamed, I.2
Flammini, L.3
Barocelli, E.4
Incerti, M.5
Lodola, A.6
Tognolini, M.7
-
52
-
-
69549120472
-
Conformational selection or induced fit: a flux description of reaction mechanism
-
10.1073/pnas.0907195106, 2728963, 19666553
-
Hammes GG, Chang YC, Oas TG. Conformational selection or induced fit: a flux description of reaction mechanism. Proc Natl Acad Sci USA 2009, 106:13737-13741. 10.1073/pnas.0907195106, 2728963, 19666553.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 13737-13741
-
-
Hammes, G.G.1
Chang, Y.C.2
Oas, T.G.3
-
53
-
-
77949587817
-
From induced fit to conformational selection: a continuum of binding mechanism controlled by the timescale of conformational transitions
-
10.1016/j.bpj.2009.11.029, 2849054, 20303846
-
Zhou HX. From induced fit to conformational selection: a continuum of binding mechanism controlled by the timescale of conformational transitions. Biophys J 2010, 98:L15-17. 10.1016/j.bpj.2009.11.029, 2849054, 20303846.
-
(2010)
Biophys J
, vol.98
-
-
Zhou, H.X.1
-
54
-
-
9944237833
-
Complementarity of structure ensembles in protein-protein binding
-
10.1016/j.str.2004.09.014, 15576027
-
Grunberg R, et al. Complementarity of structure ensembles in protein-protein binding. Structure 2004, 12:2125-2136. 10.1016/j.str.2004.09.014, 15576027.
-
(2004)
Structure
, vol.12
, pp. 2125-2136
-
-
Grunberg, R.1
-
55
-
-
73349117207
-
Conformational selection and induced fit mechanism underlie specificity in noncovalent interactions with ubiquitin
-
10.1073/pnas.0906966106, 2780739, 19887638
-
Wlodarski T, Zagrovic B. Conformational selection and induced fit mechanism underlie specificity in noncovalent interactions with ubiquitin. Proc Natl Acad Sci USA 2009, 106:19346-19351. 10.1073/pnas.0906966106, 2780739, 19887638.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 19346-19351
-
-
Wlodarski, T.1
Zagrovic, B.2
-
56
-
-
0031059866
-
Methods in enzymology
-
Academic Press, New York, NY, Carter Jr CW, Sweet RM
-
Otwinowski Z, Minor W. Methods in enzymology. 1997, 276:307-326. Academic Press, New York, NY, Carter Jr CW, Sweet RM.
-
(1997)
, vol.276
, pp. 307-326
-
-
Otwinowski, Z.1
Minor, W.2
-
57
-
-
0028103275
-
The CCP4 Suite: Programs for Protein Crystallography
-
Collaborative computational project, No. 4
-
Collaborative computational project, No. 4 The CCP4 Suite: Programs for Protein Crystallography. Acta Cryst D 1994, 50:760-763. Collaborative computational project, No. 4.
-
(1994)
Acta Cryst D
, vol.50
, pp. 760-763
-
-
-
58
-
-
46249092554
-
GROMACS 4: Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular Simulation
-
Hess B, Kutzner C, van der Spoel D, Lindahl E. GROMACS 4: Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular Simulation. J Chem Theory Comput 2008, 4:435-447.
-
(2008)
J Chem Theory Comput
, vol.4
, pp. 435-447
-
-
Hess, B.1
Kutzner, C.2
van der Spoel, D.3
Lindahl, E.4
-
59
-
-
77953513118
-
Improved side-chain torsion potentials for the Amber ff99SB protein force field
-
2970904, 20408171
-
Lindorff-Larsen K, Piana S, Palmo K, Maragakis P, Klepeis JL, Dror RO, Shaw DE. Improved side-chain torsion potentials for the Amber ff99SB protein force field. Proteins 2010, 78:1950-8. 2970904, 20408171.
-
(2010)
Proteins
, vol.78
, pp. 1950-1958
-
-
Lindorff-Larsen, K.1
Piana, S.2
Palmo, K.3
Maragakis, P.4
Klepeis, J.L.5
Dror, R.O.6
Shaw, D.E.7
-
60
-
-
0003944111
-
Molecular Modeling and Simulation: An Interdisciplinary Guide
-
New York: Springer-Verlag
-
Schlick T. Molecular Modeling and Simulation: An Interdisciplinary Guide. 2002, New York: Springer-Verlag.
-
(2002)
-
-
Schlick, T.1
-
61
-
-
0000388705
-
LINCS: A linear constraint solver for molecular simulations
-
Hess B, Bekker H, Berendsen HJC, Fraaije GEM. LINCS: A linear constraint solver for molecular simulations. J Comput Chem 1997, 18:1463-1472.
-
(1997)
J Comput Chem
, vol.18
, pp. 1463-1472
-
-
Hess, B.1
Bekker, H.2
Berendsen, H.J.C.3
Fraaije, G.E.M.4
-
62
-
-
0020997912
-
Dictionary of protein secondary structure: pattern recognition of hydrogen-bonded and geometrical features
-
10.1002/bip.360221211, 6667333
-
Kabsch W, Sander C. Dictionary of protein secondary structure: pattern recognition of hydrogen-bonded and geometrical features. Biopolymers 1983, 22:2577-637. 10.1002/bip.360221211, 6667333.
-
(1983)
Biopolymers
, vol.22
, pp. 2577-2637
-
-
Kabsch, W.1
Sander, C.2
|