Lentiviral-mediated rnai knockdown yields a novel mouse model for studying cyp2b function

Toxicological Sciences

Volumn 125, Issue 2, 2012, Pages 368-381

  Damiri, Basma ^a   Holle, Eric ^a   Yu, Xianzhong ^a   Baldwin, William S ^a  

^a CLEMSON UNIVERSITY   (United States)

Author keywords

Cyp2b; Cytochrome; Metabolism; Organophosphates; P450; Transgenics

Indexed keywords

1,4 BIS(3,5 DICHLORO 2 PYRIDYLOXY)BENZENE; COMPLEMENTARY DNA; CYTOCHROME P450 2B; ENZYME ACTIVATOR; GENOMIC DNA; LENTIVIRUS VECTOR; PARATHION; SHORT HAIRPIN RNA; ZOXAZOLAMINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG METABOLISM; DRUG TOXICITY; GENE SILENCING; GENETIC TRANSFECTION; GENOTYPE; HISTOPATHOLOGY; IMMUNOPRECIPITATION; IN VIVO STUDY; LIVER CELL; MOUSE; NONHUMAN; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; REAL TIME POLYMERASE CHAIN REACTION; RNA EXTRACTION; RNA INTERFERENCE; TRANSGENIC MOUSE; WESTERN BLOTTING;

MURINAE; MUS;

EID: 84856106494     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfr309     Document Type: Article

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